The chemical biology of nucleic acids (Wiley, 2010)
Includes bibliographical references and index
With extensive coverage of synthesis techniques and applications, this text describes chemical biology techniques which have gained significant impetus during the last five years. It focuses on the methods for obtaining modified and native nucleic acids, and their biological applications. Topics covered include: chemical synthesis of modified RNAexpansion of the genetic alphabet in nucleic acids by creating new base pairschemical biology of DNA replication: probing DNA polymerase selectivity mechanisms with modified nucleotidesnucleic-acid-temp