Evaluation of drug candidates for preclinical development: pharmacokinetics, metabolism, pharmaceutics, and toxicology
Saved in:
| Format: | Electronic eBook |
|---|---|
| Language: | English |
| Published: |
Hoboken, N.J.
John Wiley & Sons
©2010
|
| Series: | Wiley series in drug discovery and development
|
| Subjects: | |
| Online Access: | FRO01 UBG01 Volltext |
| Item Description: | Includes index Includes bibliographical references and index Explaining the assessment of potential drug compounds, this is an ideal introductory reference for those new to drug discovery. It includes sections on pharmacokinetics and drug metabolism, integration of pharmaceutical development, and predictive safety assessment. Topics include: cost analysis, drug transporters, cytochrome P-450 and drug-drug interactions, plasma protein binding, assessing stability, ways to optimize drug formulation, toxicology and toxicokinetics, and more. Readers will understand why absorption-distribution-metabolism-excretion-toxicology (ADMET) is key in drug developmen |
| Physical Description: | 1 Online-Ressource |
| ISBN: | 9780470574898 0470574895 9780470574881 0470574887 1282684906 9781282684904 |
Staff View
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| 650 | 4 | |a Drug Evaluation, Preclinical | |
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| isbn | 9780470574898 0470574895 9780470574881 0470574887 1282684906 9781282684904 |
| language | English |
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| series2 | Wiley series in drug discovery and development |
| spelling | Evaluation of drug candidates for preclinical development pharmacokinetics, metabolism, pharmaceutics, and toxicology [edited by] Chao Han, Charles B. Davis, Binghe Wang Hoboken, N.J. John Wiley & Sons ©2010 1 Online-Ressource txt rdacontent c rdamedia cr rdacarrier Wiley series in drug discovery and development Includes index Includes bibliographical references and index Explaining the assessment of potential drug compounds, this is an ideal introductory reference for those new to drug discovery. It includes sections on pharmacokinetics and drug metabolism, integration of pharmaceutical development, and predictive safety assessment. Topics include: cost analysis, drug transporters, cytochrome P-450 and drug-drug interactions, plasma protein binding, assessing stability, ways to optimize drug formulation, toxicology and toxicokinetics, and more. Readers will understand why absorption-distribution-metabolism-excretion-toxicology (ADMET) is key in drug developmen Drug Evaluation, Preclinical Drug Discovery Drug Industry / standards Pharmaceutical Preparations / metabolism Pharmacology / methods MEDICAL / Drug Guides bisacsh MEDICAL / Pharmacology bisacsh MEDICAL / Pharmacy bisacsh MEDICAL / Nursing / Pharmacology bisacsh Drug development fast Drugs / Metabolism fast Pharmacokinetics fast Medizin Drug development Pharmacokinetics Drugs / Metabolism Han, Chao Sonstige oth Davis, Charles B. Sonstige oth Wang, Binghe Sonstige oth Erscheint auch als Druck-Ausgabe, Hardcover 978-0-470-04491-9 https://onlinelibrary.wiley.com/doi/book/10.1002/9780470574898 Verlag URL des Erstveröffentlichers Volltext |
| spellingShingle | Evaluation of drug candidates for preclinical development pharmacokinetics, metabolism, pharmaceutics, and toxicology Drug Evaluation, Preclinical Drug Discovery Drug Industry / standards Pharmaceutical Preparations / metabolism Pharmacology / methods MEDICAL / Drug Guides bisacsh MEDICAL / Pharmacology bisacsh MEDICAL / Pharmacy bisacsh MEDICAL / Nursing / Pharmacology bisacsh Drug development fast Drugs / Metabolism fast Pharmacokinetics fast Medizin Drug development Pharmacokinetics Drugs / Metabolism |
| title | Evaluation of drug candidates for preclinical development pharmacokinetics, metabolism, pharmaceutics, and toxicology |
| title_auth | Evaluation of drug candidates for preclinical development pharmacokinetics, metabolism, pharmaceutics, and toxicology |
| title_exact_search | Evaluation of drug candidates for preclinical development pharmacokinetics, metabolism, pharmaceutics, and toxicology |
| title_full | Evaluation of drug candidates for preclinical development pharmacokinetics, metabolism, pharmaceutics, and toxicology [edited by] Chao Han, Charles B. Davis, Binghe Wang |
| title_fullStr | Evaluation of drug candidates for preclinical development pharmacokinetics, metabolism, pharmaceutics, and toxicology [edited by] Chao Han, Charles B. Davis, Binghe Wang |
| title_full_unstemmed | Evaluation of drug candidates for preclinical development pharmacokinetics, metabolism, pharmaceutics, and toxicology [edited by] Chao Han, Charles B. Davis, Binghe Wang |
| title_short | Evaluation of drug candidates for preclinical development |
| title_sort | evaluation of drug candidates for preclinical development pharmacokinetics metabolism pharmaceutics and toxicology |
| title_sub | pharmacokinetics, metabolism, pharmaceutics, and toxicology |
| topic | Drug Evaluation, Preclinical Drug Discovery Drug Industry / standards Pharmaceutical Preparations / metabolism Pharmacology / methods MEDICAL / Drug Guides bisacsh MEDICAL / Pharmacology bisacsh MEDICAL / Pharmacy bisacsh MEDICAL / Nursing / Pharmacology bisacsh Drug development fast Drugs / Metabolism fast Pharmacokinetics fast Medizin Drug development Pharmacokinetics Drugs / Metabolism |
| topic_facet | Drug Evaluation, Preclinical Drug Discovery Drug Industry / standards Pharmaceutical Preparations / metabolism Pharmacology / methods MEDICAL / Drug Guides MEDICAL / Pharmacology MEDICAL / Pharmacy MEDICAL / Nursing / Pharmacology Drug development Drugs / Metabolism Pharmacokinetics Medizin |
| url | https://onlinelibrary.wiley.com/doi/book/10.1002/9780470574898 |
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