Protein-ligand interactions from molecular recognition to drug design:
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Bibliographic Details
Format: Electronic eBook
Language:English
Published: Weinheim Wiley-VCH © 2003
Series:Methods and principles in medicinal chemistry v. 19
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Online Access:FRO01
UBG01
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Item Description:Includes bibliographical references and index
The lock-and-key principle formulated by Emil Fischer as early as the end of the 19th century has still not lost any of its significance for the life sciences. The basic aspects of ligand-protein interaction may be summarized under the term 'molecular recognition' and concern the specificity as well as stability of ligand binding. Molecular recognition is thus a central topic in the development of active substances, since stability and specificity determine whether a substance can be used as a drug. Nowadays, computer-aided prediction and intelligent molecular design make a large contribution
Physical Description:1 Online-Ressource (xx, 242 pages)
ISBN:3527605517
9783527605514
3527305211
9783527305216
3527601813
9783527601813

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