Drug bioavailability: estimation of solubility, permeability, absorption and bioavailability
Gespeichert in:
| Format: | Elektronisch E-Book |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
Weinheim
Wiley-VCH
©2003
|
| Schriftenreihe: | Methods and principles in medicinal chemistry
v. 18 |
| Schlagworte: | |
| Online-Zugang: | FRO01 UBG01 URL des Erstveröffentlichers |
| Beschreibung: | Includes bibliographical references and index The peroral application (swallowing) of a medicine means that the body must first resorb the active substance before it can begin to take effect. The efficacy of drug uptake depends on the one hand on the chemical characteristics of the active substance, above all on its solubility and membrane permeability. On the other hand, it is determined by the organism's ability to absorb pharmaceuticals by way of specific transport proteins or to excrete them. Since many pharmacologically active substances are poorly suited for oral intake, a decisive criterion for the efficacy of a medicine is its so- |
| Beschreibung: | 1 Online-Ressource (xxiv, 579 pages) |
| ISBN: | 3527601473 9783527601479 3527605150 9783527605156 9783527304387 352730438X |
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| 490 | 0 | |a Methods and principles in medicinal chemistry |v v. 18 | |
| 500 | |a Includes bibliographical references and index | ||
| 500 | |a The peroral application (swallowing) of a medicine means that the body must first resorb the active substance before it can begin to take effect. The efficacy of drug uptake depends on the one hand on the chemical characteristics of the active substance, above all on its solubility and membrane permeability. On the other hand, it is determined by the organism's ability to absorb pharmaceuticals by way of specific transport proteins or to excrete them. Since many pharmacologically active substances are poorly suited for oral intake, a decisive criterion for the efficacy of a medicine is its so- | ||
| 650 | 4 | |a Biological Availability | |
| 650 | 4 | |a Pharmaceutical Preparations / administration & dosage | |
| 650 | 4 | |a Pharmaceutical Preparations / metabolism | |
| 650 | 4 | |a Pharmacokinetics | |
| 650 | 7 | |a MEDICAL / Pharmacology |2 bisacsh | |
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Datensatz im Suchindex
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| dewey-full | 615/.7 |
| dewey-hundreds | 600 - Technology (Applied sciences) |
| dewey-ones | 615 - Pharmacology and therapeutics |
| dewey-raw | 615/.7 |
| dewey-search | 615/.7 |
| dewey-sort | 3615 17 |
| dewey-tens | 610 - Medicine and health |
| discipline | Medizin |
| format | Electronic eBook |
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| indexdate | 2024-07-10T07:24:28Z |
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| isbn | 3527601473 9783527601479 3527605150 9783527605156 9783527304387 352730438X |
| language | English |
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| series2 | Methods and principles in medicinal chemistry |
| spelling | Drug bioavailability estimation of solubility, permeability, absorption and bioavailability edited by Han van de Waterbeemd, Hans Lennernäs and Per Artursson Weinheim Wiley-VCH ©2003 1 Online-Ressource (xxiv, 579 pages) txt rdacontent c rdamedia cr rdacarrier Methods and principles in medicinal chemistry v. 18 Includes bibliographical references and index The peroral application (swallowing) of a medicine means that the body must first resorb the active substance before it can begin to take effect. The efficacy of drug uptake depends on the one hand on the chemical characteristics of the active substance, above all on its solubility and membrane permeability. On the other hand, it is determined by the organism's ability to absorb pharmaceuticals by way of specific transport proteins or to excrete them. Since many pharmacologically active substances are poorly suited for oral intake, a decisive criterion for the efficacy of a medicine is its so- Biological Availability Pharmaceutical Preparations / administration & dosage Pharmaceutical Preparations / metabolism Pharmacokinetics MEDICAL / Pharmacology bisacsh Drugs / Bioavailability fast Medizin Drugs / Bioavailability Bioverfügbarkeit (DE-588)4145660-9 gnd rswk-swf Arzneimittel (DE-588)4003115-9 gnd rswk-swf Pharmazeutische Chemie (DE-588)4132158-3 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content Pharmazeutische Chemie (DE-588)4132158-3 s Arzneimittel (DE-588)4003115-9 s Bioverfügbarkeit (DE-588)4145660-9 s DE-604 Waterbeemd, Han van de Sonstige oth Lennernäs, Hans Sonstige oth Artursson, Per Sonstige oth https://onlinelibrary.wiley.com/doi/book/10.1002/3527601473 Verlag URL des Erstveröffentlichers Volltext |
| spellingShingle | Drug bioavailability estimation of solubility, permeability, absorption and bioavailability Biological Availability Pharmaceutical Preparations / administration & dosage Pharmaceutical Preparations / metabolism Pharmacokinetics MEDICAL / Pharmacology bisacsh Drugs / Bioavailability fast Medizin Drugs / Bioavailability Bioverfügbarkeit (DE-588)4145660-9 gnd Arzneimittel (DE-588)4003115-9 gnd Pharmazeutische Chemie (DE-588)4132158-3 gnd |
| subject_GND | (DE-588)4145660-9 (DE-588)4003115-9 (DE-588)4132158-3 (DE-588)4143413-4 |
| title | Drug bioavailability estimation of solubility, permeability, absorption and bioavailability |
| title_auth | Drug bioavailability estimation of solubility, permeability, absorption and bioavailability |
| title_exact_search | Drug bioavailability estimation of solubility, permeability, absorption and bioavailability |
| title_full | Drug bioavailability estimation of solubility, permeability, absorption and bioavailability edited by Han van de Waterbeemd, Hans Lennernäs and Per Artursson |
| title_fullStr | Drug bioavailability estimation of solubility, permeability, absorption and bioavailability edited by Han van de Waterbeemd, Hans Lennernäs and Per Artursson |
| title_full_unstemmed | Drug bioavailability estimation of solubility, permeability, absorption and bioavailability edited by Han van de Waterbeemd, Hans Lennernäs and Per Artursson |
| title_short | Drug bioavailability |
| title_sort | drug bioavailability estimation of solubility permeability absorption and bioavailability |
| title_sub | estimation of solubility, permeability, absorption and bioavailability |
| topic | Biological Availability Pharmaceutical Preparations / administration & dosage Pharmaceutical Preparations / metabolism Pharmacokinetics MEDICAL / Pharmacology bisacsh Drugs / Bioavailability fast Medizin Drugs / Bioavailability Bioverfügbarkeit (DE-588)4145660-9 gnd Arzneimittel (DE-588)4003115-9 gnd Pharmazeutische Chemie (DE-588)4132158-3 gnd |
| topic_facet | Biological Availability Pharmaceutical Preparations / administration & dosage Pharmaceutical Preparations / metabolism Pharmacokinetics MEDICAL / Pharmacology Drugs / Bioavailability Medizin Bioverfügbarkeit Arzneimittel Pharmazeutische Chemie Aufsatzsammlung |
| url | https://onlinelibrary.wiley.com/doi/book/10.1002/3527601473 |
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