Verfügbarkeit: Chromosomal Translocations and Genome Rearrangements in Cancer

Chromosomal Translocations and Genome Rearrangements in Cancer:

Gespeichert in:

Bibliographische Detailangaben
Format:	Elektronisch E-Book
Sprache:	English
Veröffentlicht:	Cham Springer 2015
Schlagworte:	Medicine Cancer research Human genetics Molecular biology Cell biology Biomedicine Cancer Research Cell Biology Human Genetics Molecular Medicine Medizin
Online-Zugang:	TUM01 UBT01 Volltext Inhaltsverzeichnis Abstract
Beschreibung:	1 Online Ressource (IX, 490 p. 72 illus., 69 illus. in color)
ISBN:	9783319199832
DOI:	10.1007/978-3-319-19983-2

Internformat

MARC


LEADER	00000nmm a2200000zc 4500
001	BV043309453
003	DE-604
005	20160125
007	cr\|uuu---uuuuu
008	160125s2015 \|\|\|\| o\|\|u\| \|\|\|\|\|\|eng d
020			\|a 9783319199832 \|c Online \|9 978-3-319-19983-2
024	7		\|a 10.1007/978-3-319-19983-2 \|2 doi
035			\|a (OCoLC)934179153
035			\|a (DE-599)BVBBV043309453
040			\|a DE-604 \|b ger \|e aacr
041	0		\|a eng
049			\|a DE-91 \|a DE-703
082	0		\|a 614.5999 \|2 23
084			\|a WG 1940 \|0 (DE-625)148511: \|2 rvk
084			\|a BIO 000 \|2 stub
245	1	0	\|a Chromosomal Translocations and Genome Rearrangements in Cancer \|c Janet D. Rowley, Michelle M. Le Beau, Terence H. Rabbitts, ed.
264		1	\|a Cham \|b Springer \|c 2015
300			\|a 1 Online Ressource (IX, 490 p. 72 illus., 69 illus. in color)
336			\|b txt \|2 rdacontent
337			\|b c \|2 rdamedia
338			\|b cr \|2 rdacarrier
650		4	\|a Medicine
650		4	\|a Cancer research
650		4	\|a Human genetics
650		4	\|a Molecular biology
650		4	\|a Cell biology
650		4	\|a Biomedicine
650		4	\|a Cancer Research
650		4	\|a Cell Biology
650		4	\|a Human Genetics
650		4	\|a Molecular Medicine
650		4	\|a Medizin
700	1		\|a Rowley, Janet D. \|d 1925-2013 \|e Sonstige \|0 (DE-588)1081463120 \|4 oth
700	1		\|a Le Beau, Michelle M. \|e Sonstige \|0 (DE-588)1081463392 \|4 oth
700	1		\|a Rabbitts, Terence H. \|e Sonstige \|4 oth
776	0	8	\|i Erscheint auch als \|n Druckausgabe \|z 978-3-319-19982-5
856	4	0	\|u https://doi.org/10.1007/978-3-319-19983-2 \|x Verlag \|3 Volltext
856	4	2	\|m Springer Fremddatenuebernahme \|q application/pdf \|u http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=028730142&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA \|3 Inhaltsverzeichnis
856	4	2	\|m Springer Fremddatenuebernahme \|q application/pdf \|u http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=028730142&sequence=000003&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA \|3 Abstract
912			\|a ZDB-2-SBL
940	1		\|q ZDB-2-SBL_2015
999			\|a oai:aleph.bib-bvb.de:BVB01-028730142
966	e		\|u https://doi.org/10.1007/978-3-319-19983-2 \|l TUM01 \|p ZDB-2-SBL \|x Verlag \|3 Volltext
966	e		\|u https://doi.org/10.1007/978-3-319-19983-2 \|l UBT01 \|p ZDB-2-SBL \|x Verlag \|3 Volltext

Datensatz im Suchindex

_version_	1804175846287605760
adam_text	CHROMOSOMAL TRANSLOCATIONS AND GENOME REARRANGEMENTS IN CANCER / : 2015 TABLE OF CONTENTS / INHALTSVERZEICHNIS PART I INTRODUCTION A SHORT HISTORY OF CHROMOSOME REARRANGEMENTS AND GENE FUSIONS IN CANCER PART II GENERAL MOLECULAR GENETICS METHODS IN DISCOVERY OF CHROMOSOME STRUCTURE MECHANISM OF RECURRENT CHROMOSOMAL TRANSLOCATIONS CHROMOSOME TRANSLOCATIONS, CANCER INITIATION AND CLONAL EVOLUTION.-CHROMOSOMAL FRAGILE SITES AND CANCER COPY NUMBER CHANGES IN CARCINOMAS: APPLICATIONS PART III LEUKAEMIA/LYMPHOMA CHRONIC MYELOID LEUKAEMIA IMMUNOGLOBULIN AND MYC REARRANGEMENTS IN MULTIPLE MYELOMA PATHOGENESIS GENETIC ALTERATIONS IN B CELL LYMPHOMA CHROMOSOMAL TRANSLOCATIONS AND GENE REARRANGEMENTS IN ACUTE LYMPHOBLASTIC LEUKAEMIA CELLULAR AND MOLECULAR BASIS OF MLL LEUKAEMIAS: FROM TRANSFORMATION MECHANISMS TO NOVEL THERAPEUTIC STRATEGIES ACUTE PROMYELOCYTIC LEUKAEMIA: FROM A SPECIFIC TRANSLOCATION TO CURE BY TARGETED THERAPIES CHROMOSOME ABNORMALITIES IN AML AND THEIR CLINICAL IMPORTANCE PART IV SARCOMAS FUSION ONCOGENES OF SARCOMAS TRANSLOCATIONS IN EWING SARCOMA PART V EPITHELIAL TUMOURS RET AND THYROID CARCINOMAS GENE FUSIONS IN PROSTATE CANCER CHROMOSOMAL TRANSLOCATIONS IN LUNG CANCER COLON & OVARIAN TRANSLOCATIONS PART VI OTHER ASPECTS PRE-CLINICAL MODELING OF CHROMOSOMAL TRANSLOCATIONS AND INVERSIONS PROTEIN COMPLEX HIERARCHY & TRANSLOCATION GENE PRODUCTS ABERRANT TRANSCRIPTIONAL PROGRAMMING IN BLOOD CANCERS INDEX DIESES SCHRIFTSTUECK WURDE MASCHINELL ERZEUGT. CHROMOSOMAL TRANSLOCATIONS AND GENOME REARRANGEMENTS IN CANCER / : 2015 ABSTRACT / INHALTSTEXT THIS VOLUME COLLATES WORLD EXPERTS’ INSIGHTS INTO THE MOLECULAR BIOLOGY OF CANCER CHROMOSOMES, THEIR ABNORMALITIES AND THE SUBSEQUENT CELLULAR CONSEQUENCES. EXPLORING THEMES INVOLVING ONCOGENES, SUCH AS BY CHROMOSOMAL TRANSLOCATIONS, OTHER GENOME REARRANGEMENTS AND SOMATIC MUTATIONS, THIS BOOK IS A REVIEW OF THE FIELD OF CANCER GENETICS THAT PRESAGES A NEW ERA, AS WHOLE GENOME SEQUENCING BECOMES MORE ACCESSIBLE. THE WORK BEGINS WITH A LOOK AT HISTORICAL THEMES, SUCH AS THE ANALYSIS OF METAPHASE CHROMOSOMES USING MICROSCOPY AND STAINING TECHNIQUES, ADVANCES IN WHICH PROVIDED OUR FIRST BROAD GLIMPSE INTO THE GENETIC ANATOMY OF A MALIGNANT CELL. READERS WILL LEARN ABOUT THE APPLICATION OF DNA MOLECULAR CLONING TECHNIQUES IN THE 1980S, THAT LED TO THE IDENTIFICATION OF THE GENES INVOLVED IN THE PHILADELPHIA AND BURKITT S LYMPHOMA CHROMOSOMAL TRANSLOCATIONS, SOLIDIFYING THE ROLE OF ONCOGENES AND TUMOUR SUPPRESSOR GENES IN CANCER AETIOLOGY VIA CHROMOSOMAL ALTERATIONS, AND WHICH LAUNCHED A FIELD IN CANCER GENETICS. SUBSEQUENT CHAPTERS BRING THE READER UP TO DATE BY REVIEWING RECENT DEVELOPMENTS IN THE FIELD, WITH DEDICATED SECTIONS ON LEUKAEMIA/LYMPHOMA, SARCOMAS AND EPITHELIAL TUMOURS. CONTRIBUTIONS FEATURE NUMEROUS COLOUR TABLES AND ILLUSTRATIONS AND THIS VOLUME WILL PROVIDE A BASIS FOR UNDERSTANDING CANCER CHROMOSOMES FOR MANY YEARS TO COME DIESES SCHRIFTSTUECK WURDE MASCHINELL ERZEUGT.
any_adam_object	1
author_GND	(DE-588)1081463120 (DE-588)1081463392
building	Verbundindex
bvnumber	BV043309453
classification_rvk	WG 1940
classification_tum	BIO 000
collection	ZDB-2-SBL
ctrlnum	(OCoLC)934179153 (DE-599)BVBBV043309453
dewey-full	614.5999
dewey-hundreds	600 - Technology (Applied sciences)
dewey-ones	614 - Forensic medicine; incidence of disease
dewey-raw	614.5999
dewey-search	614.5999
dewey-sort	3614.5999
dewey-tens	610 - Medicine and health
discipline	Biologie Medizin
doi_str_mv	10.1007/978-3-319-19983-2
format	Electronic eBook
fullrecord	<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>02369nmm a2200553zc 4500</leader><controlfield tag="001">BV043309453</controlfield><controlfield tag="003">DE-604</controlfield><controlfield tag="005">20160125 </controlfield><controlfield tag="007">cr\|uuu---uuuuu</controlfield><controlfield tag="008">160125s2015 \|\|\|\| o\|\|u\| \|\|\|\|\|\|eng d</controlfield><datafield tag="020" ind1=" " ind2=" "><subfield code="a">9783319199832</subfield><subfield code="c">Online</subfield><subfield code="9">978-3-319-19983-2</subfield></datafield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1007/978-3-319-19983-2</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(OCoLC)934179153</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-599)BVBBV043309453</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-604</subfield><subfield code="b">ger</subfield><subfield code="e">aacr</subfield></datafield><datafield tag="041" ind1="0" ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="049" ind1=" " ind2=" "><subfield code="a">DE-91</subfield><subfield code="a">DE-703</subfield></datafield><datafield tag="082" ind1="0" ind2=" "><subfield code="a">614.5999</subfield><subfield code="2">23</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">WG 1940</subfield><subfield code="0">(DE-625)148511:</subfield><subfield code="2">rvk</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">BIO 000</subfield><subfield code="2">stub</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Chromosomal Translocations and Genome Rearrangements in Cancer</subfield><subfield code="c">Janet D. Rowley, Michelle M. Le Beau, Terence H. Rabbitts, ed.</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="a">Cham</subfield><subfield code="b">Springer</subfield><subfield code="c">2015</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">1 Online Ressource (IX, 490 p. 72 illus., 69 illus. in color)</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Medicine</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Cancer research</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Human genetics</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Molecular biology</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Cell biology</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Biomedicine</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Cancer Research</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Cell Biology</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Human Genetics</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Molecular Medicine</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Medizin</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Rowley, Janet D.</subfield><subfield code="d">1925-2013</subfield><subfield code="e">Sonstige</subfield><subfield code="0">(DE-588)1081463120</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Le Beau, Michelle M.</subfield><subfield code="e">Sonstige</subfield><subfield code="0">(DE-588)1081463392</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Rabbitts, Terence H.</subfield><subfield code="e">Sonstige</subfield><subfield code="4">oth</subfield></datafield><datafield tag="776" ind1="0" ind2="8"><subfield code="i">Erscheint auch als</subfield><subfield code="n">Druckausgabe</subfield><subfield code="z">978-3-319-19982-5</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://doi.org/10.1007/978-3-319-19983-2</subfield><subfield code="x">Verlag</subfield><subfield code="3">Volltext</subfield></datafield><datafield tag="856" ind1="4" ind2="2"><subfield code="m">Springer Fremddatenuebernahme</subfield><subfield code="q">application/pdf</subfield><subfield code="u">http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=028730142&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA</subfield><subfield code="3">Inhaltsverzeichnis</subfield></datafield><datafield tag="856" ind1="4" ind2="2"><subfield code="m">Springer Fremddatenuebernahme</subfield><subfield code="q">application/pdf</subfield><subfield code="u">http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=028730142&sequence=000003&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA</subfield><subfield code="3">Abstract</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">ZDB-2-SBL</subfield></datafield><datafield tag="940" ind1="1" ind2=" "><subfield code="q">ZDB-2-SBL_2015</subfield></datafield><datafield tag="999" ind1=" " ind2=" "><subfield code="a">oai:aleph.bib-bvb.de:BVB01-028730142</subfield></datafield><datafield tag="966" ind1="e" ind2=" "><subfield code="u">https://doi.org/10.1007/978-3-319-19983-2</subfield><subfield code="l">TUM01</subfield><subfield code="p">ZDB-2-SBL</subfield><subfield code="x">Verlag</subfield><subfield code="3">Volltext</subfield></datafield><datafield tag="966" ind1="e" ind2=" "><subfield code="u">https://doi.org/10.1007/978-3-319-19983-2</subfield><subfield code="l">UBT01</subfield><subfield code="p">ZDB-2-SBL</subfield><subfield code="x">Verlag</subfield><subfield code="3">Volltext</subfield></datafield></record></collection>
id	DE-604.BV043309453
illustrated	Not Illustrated
indexdate	2024-07-10T07:22:46Z
institution	BVB
isbn	9783319199832
language	English
oai_aleph_id	oai:aleph.bib-bvb.de:BVB01-028730142
oclc_num	934179153
open_access_boolean
owner	DE-91 DE-BY-TUM DE-703
owner_facet	DE-91 DE-BY-TUM DE-703
physical	1 Online Ressource (IX, 490 p. 72 illus., 69 illus. in color)
psigel	ZDB-2-SBL ZDB-2-SBL_2015
publishDate	2015
publishDateSearch	2015
publishDateSort	2015
publisher	Springer
record_format	marc
spelling	Chromosomal Translocations and Genome Rearrangements in Cancer Janet D. Rowley, Michelle M. Le Beau, Terence H. Rabbitts, ed. Cham Springer 2015 1 Online Ressource (IX, 490 p. 72 illus., 69 illus. in color) txt rdacontent c rdamedia cr rdacarrier Medicine Cancer research Human genetics Molecular biology Cell biology Biomedicine Cancer Research Cell Biology Human Genetics Molecular Medicine Medizin Rowley, Janet D. 1925-2013 Sonstige (DE-588)1081463120 oth Le Beau, Michelle M. Sonstige (DE-588)1081463392 oth Rabbitts, Terence H. Sonstige oth Erscheint auch als Druckausgabe 978-3-319-19982-5 https://doi.org/10.1007/978-3-319-19983-2 Verlag Volltext Springer Fremddatenuebernahme application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=028730142&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis Springer Fremddatenuebernahme application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=028730142&sequence=000003&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA Abstract
spellingShingle	Chromosomal Translocations and Genome Rearrangements in Cancer Medicine Cancer research Human genetics Molecular biology Cell biology Biomedicine Cancer Research Cell Biology Human Genetics Molecular Medicine Medizin
title	Chromosomal Translocations and Genome Rearrangements in Cancer
title_auth	Chromosomal Translocations and Genome Rearrangements in Cancer
title_exact_search	Chromosomal Translocations and Genome Rearrangements in Cancer
title_full	Chromosomal Translocations and Genome Rearrangements in Cancer Janet D. Rowley, Michelle M. Le Beau, Terence H. Rabbitts, ed.
title_fullStr	Chromosomal Translocations and Genome Rearrangements in Cancer Janet D. Rowley, Michelle M. Le Beau, Terence H. Rabbitts, ed.
title_full_unstemmed	Chromosomal Translocations and Genome Rearrangements in Cancer Janet D. Rowley, Michelle M. Le Beau, Terence H. Rabbitts, ed.
title_short	Chromosomal Translocations and Genome Rearrangements in Cancer
title_sort	chromosomal translocations and genome rearrangements in cancer
topic	Medicine Cancer research Human genetics Molecular biology Cell biology Biomedicine Cancer Research Cell Biology Human Genetics Molecular Medicine Medizin
topic_facet	Medicine Cancer research Human genetics Molecular biology Cell biology Biomedicine Cancer Research Cell Biology Human Genetics Molecular Medicine Medizin
url	https://doi.org/10.1007/978-3-319-19983-2 http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=028730142&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=028730142&sequence=000003&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA
work_keys_str_mv	AT rowleyjanetd chromosomaltranslocationsandgenomerearrangementsincancer AT lebeaumichellem chromosomaltranslocationsandgenomerearrangementsincancer AT rabbittsterenceh chromosomaltranslocationsandgenomerearrangementsincancer

Verfügbarkeit

Es ist kein Print-Exemplar vorhanden.

Fernleihe Bestellen Achtung: Nicht im THWS-Bestand! Volltext öffnen

MARC

Datensatz im Suchindex

Es ist kein Print-Exemplar vorhanden.

Ähnliche Einträge