Biopsy diagnosis of peripheral neuropathy:
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| Previous Title: | Biopsy diagnosis of peripheral neuropathy |
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| Main Authors: | , |
| Format: | Book |
| Language: | English |
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Cham ; Heidelberg ; New York ; Dordrecht ; London
Springer
2015
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| Edition: | 2. ed. |
| Series: | Pathology
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| Subjects: | |
| Online Access: | Cover Inhaltsverzeichnis |
| Item Description: | Literaturangaben |
| Physical Description: | XXI, 486 S. Ill., graf. Darst. 29 cm |
| ISBN: | 9783319073101 |
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| 245 | 1 | 0 | |a Biopsy diagnosis of peripheral neuropathy |c Juan M. Bilbao ; Robert E. Schmidt |
| 250 | |a 2. ed. | ||
| 264 | 1 | |a Cham ; Heidelberg ; New York ; Dordrecht ; London |b Springer |c 2015 | |
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| 650 | 4 | |a Neurosciences | |
| 650 | 4 | |a Neurology | |
| 650 | 4 | |a Neurosurgery | |
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Titel: Biopsy diagnosis of peripheral neuropathy
Autor: Bilbao, Juan M
Jahr: 2015
Contents
1 Peripheral Neuropathy and the Role of Nerve Biopsy.1
1.1 Epidemiology of Peripheral Neuropathy.1
1.1.1 Etiologies of Peripheral Neuropathy.1
1.1.2 Cryptogenic Peripheral Neuropathy.2
1.2 Usefulness of Nerve Biopsy in Evaluation of Peripheral Neuropathy.3
1.2.1 Review of Experience at St. Michael's Hospital.3
1.2.2 Literature Data on the Usefulness of Nerve Biopsy.5
1.3 Indications for Nerve Biopsy.5
1.3.1 Clinical and Electrophysiological Criteria Cannot
Exclude the Need for Biopsy.6
1.3.2 Nerve Biopsy Has Limited Usefulness in Suspected CIDP.6
1.3.3 Suggested Guidelines for Use of Nerve Biopsy.7
1.4 Site of Biopsy.7
1.4.1 Alternative Biopsy Sites.7
1.4.2 Nerve to Be Biopsied.S
1.4.3 Combined Muscle and Nerve Biopsy.8
1.4.4 Fascicular vs. Whole Nerve Biopsy.9
1.5 Sequelae of Nerve Biopsy.9
1.5.1 Delayed Healing, Wound Infections, and Neuroma Formation.9
1.5.2 Temporary Discomfort.9
1.5.3 Lasting Discomfort.9
1.6 Future Directions.9
1.6.1 Skin Biopsy.9
1.6.2 Imaging of the Peripheral Nervous System.14
1.6.3 Molecular Techniques.15
References.18
2 Normal Anatomy of the Peripheral (Sural) Nerve.21
2.1 Normal Peripheral Nerve Structure and Function.21
2.1.1 Macroscopic Anatomy of the Sural Nerve.21
2.1.2 The Microscopic Architecture of Nerves.22
2.1.3 Other Endoneurial Cell Content.29
2.2 Age-Related Changes.36
2.2.1 Aged Individuals.36
2.2.2 Early Life.37
2.2.3 Age-Related "Degenerative" Changes.38
References.39
3 Quantitative Techniques.43
3.1 Fiber Teasing.43
3.2 The Morphometric Study of Nerve Biopsies.44
3.2.1 Fiber Counts and Histograms.45
3.2.2 Usefulness of Fiber Counts and Histograms in
Assessment of Nerve Biopsy.46
3.2.3 TheG-Ratio.46
3.2.4 Endoneurial Area and Cell Counts.47
3.2.5 Regenerating Clusters.48
3.2.6 Assessment of Unmyelinated Fiber Loss.48
3.2.7 Internode Length.48
3.3 Summary: The Utility of Morphometric Analysis.49
References.49
4 The Axon: Normal Structure and Pathological Alterations.51
4.1 The Normal Axon.51
4.1.1 Contents of the Normal Axon.51
4.1.2 Organization of Axonal Structure.53
4.1.3 Axonal Transport.54
4.1.4 Regulation of Axonal Diameter.56
4.2 Axonal Degeneration.56
4.2.1 Distal Axonopathy.56
4.2.2 Pathological Alterations in Axonopathy.57
4.3 Wallerian Degeneration.63
4.3.1 Changes Distal to Transection.64
4.3.2 Mechanisms of Wallerian Degeneration.72
4.4 Axonal Pathology in Nerve Biopsy Specimens.73
4.4.1 Axonal Inclusions.74
4.5 Axonal Regeneration.75
4.5.1 Mechanisms of Regeneration.75
4.5.2 Histological Hallmarks of Regeneration.79
References.80
5 Schwann Cells and Myelin in the Peripheral Nervous System.85
5.1 Normal Structure and Function of Schwann Cells and Myelin.85
5.1.1 Myelinating Schwann Cells.85
5.1.2 Myelin.89
5.1.3 Nonmyelinating Schwann cells.90
5.1.4 Schwann Cell Inclusions.91
5.2 Demyelination.94
5.2.1 Nonspecific Features of Demyelination.95
5.2.2 Specific Myelin Changes in Primary Demyelinating Neuropathies. 96
5.2.3 Schwannopathy.101
5.2.4 Secondary Demyelination.101
5.2.5 Mechanisms of Demyelination.102
5.3 Remyelination.103
5.3.1 Normal Remyelination.103
5.3.2 Onion-Bulb Formation.104
References.105
6 The Peripheral Nerve Vasculature.Ill
6.1 Normal Structure and Function.Ill
6.1.1 Vascular Anatomy.Ill
6.1.2 Resistance of Peripheral Nerve to Ischemia.113
6.1.3 The Blood-Nerve Barrier.114
6.2 Pathological Alterations.115
6.2.1 Alteration in the Blood-Nerve Barrier in Neuropathy.115
6.2.2 Endoneurial "Edema".116
6.2.3 Significance of Alterations in the Blood-Nerve Barrier.117
6.3 Focal Ischemic Injury of Peripheral Nerves.117
6.3.1 Fascicular Geography of Nerve Damage.118
6.3.2 Involvement of Endoneurial Contents.118
6.4 Chronic Vascular Insufficiency.119
6.5 Chronic Hypoxemia.120
References.120
7 Examination of the Peripheral Nerve Biopsy.123
7.1 Methods.123
7.1.1 Paraffin-Embedded Sections.123
7.1.2 Plastic-Embedded Sections.123
7.1.3 Frozen Sections.124
7.1.4 Fiber Teasing.124
7.2 Approach to Specimen Examination.124
7.2.1 Biopsy Examination.124
7.2.2 Essential Points to Be Addressed by the Examination.124
7.3 Assessment of Specimen Quality.124
7.4 Light Microscopy.127
7.4.1 Examination of the Epineurium.127
7.4.2 Examination of the Perineurium.133
7.4.3 Examination of the Endoneurium.135
7.5 Electron Microscopy.140
7.5.1 Assessment of Unmyelinated Fibers.140
7.5.2 Electron Microscopy: Assessment of Myelin
and Demyelination.142
7.5.3 Axonal Ultrastructural Changes.144
7.5.4 Ultrastructural Examination of Inclusions in Endoneurial Cells.146
7.5.5 The Interstitial Compartment.147
7.6 Immunohistochemical Techniques.147
7.7 Fiber Teasing.148
References.148
8 Clinical Aspects of Peripheral Neuropathy.151
8.1 Clinical Approach to Peripheral Neuropathy.151
8.1.1 Clinical Questions.151
8.2 Classification of Peripheral Neuropathies.154
8.3 Laboratory Testing in Peripheral Neuropathy.155
8.3.1 Electrophysiological Testing.155
References.158
9 The Inflammatory Demyelinating Neuropathies.161
9.1 Guillain-Barré Syndrome.161
9.1.1 Clinical Manifestations.161
9.1.2 Pathology.162
9.1.3 Pathogenesis.169
9.1.4 Differential Diagnosis.174
9.2 Chronic Inflammatory Demyelinating Polyradiculoneuropathy.174
9.2.1 Clinical Manifestations.174
9.2.2 Pathology.175
9.2.3 Pathogenesis.186
9.2.4 Differential Diagnosis.187
9.3 Multifocal Neuropathy with Persistent Conduction Block.190
9.3.1 Clinical Syndrome.190
9.3.2 Findings in Multifocal Motor Neuropathy with
Persistent Conduction Block.190
9.3.3 Pathogenesis.192
References.192
10 Idiopathic Inflammatory Neuropathies.197
10.1 Sarcoidosis.197
10.1.1 Clinical Manifestations.197
10.1.2 Pathology.197
10.1.3 Pathogenesis.199
10.1.4 Differential Diagnosis.199
10.2 Idiopathic Perineuritis.201
10.2.1 Clinical Manifestations.201
10.2.2 Pathology.201
10.2.3 Pathogenesis.205
10.2.4 Differential Diagnosis.205
References.206
11 Infectious Diseases Causing Neuropathy.209
11.1 HIV Infection.209
11.1.1 Distal Symmetrical Polyneuropathy (DSPN).210
11.1.2 Inflammatory Demyelinating Polyneuropathy
in HIV Infection.212
11.1.3 Mononeuropathy Multiplex and Vasculitic Neuropathy in
HIV Infection.212
11.1.4 Cytomegalovirus-Associated Neuropathy.215
11.1.5 Role of Nerve Biopsy in HIV Patients with Neuropathy.216
11.1.6 Differential Diagnosis.216
11.2 Neuropathy Associated with HTLV-I Infection.217
11.2.1 Clinical Features.217
11.2.2 Pathology.217
11.2.3 Pathogenesis.217
11.3 Neuropathy of Lyme Disease (Lyme Neuroborreliosis).217
11.3.1 Clinical Manifestations.217
11.3.2 Pathology.218
11.3.3 Pathogenesis.218
11.3.4 Differential Diagnosis.219
11.4 Non-Lyme Peripheral Neuropathy with Arthropod Stings.219
11.5 Other Infection-Associated Neuropathies.219
11.5.1 Diphtheritic Polyneuropathy.219
11.5.2 Herpes Zoster ("Shingles").220
11.5.3 Syphilitic Neuropathy.220
11.5.4 Neuropathy in Creutzfeldt-Jakob Disease.220
References.222
12 Leprous Neuropathy.225
12.1 Clinical Manifestations.226
12.1.1 Lepromatous Leprosy.226
12.1.2 Tuberculoid Leprosy.227
12.1.3 Borderline Leprosy.227
12.1.4 Pure Neuritic Leprosy.227
12.1.5 Acute Neuritis.228
12.1.6 Treatment of Leprosy.228
12.2 Pathology.228
12.2.1 General Considerations.228
12.2.2 Lepromatous Leprosy.228
12.2.3 Tuberculoid Leprosy.235
12.2.4 Borderline Leprosy.236
12.2.5 Indeterminate Leprosy.237
12.2.6 Primary Neuritic Leprosy.238
12.2.7 Acute Neuritis.238
12.3 Pathogenesis.240
12.3.1 Mechanism of Organism Spread.240
12.3.2 Mechanism of Nerve Injury.240
12.4 Differential Diagnosis.241
References.242
13 Vasculitic Neuropathy.245
13.1 Clinical Manifestations.246
13.1.1 Mononeuritis Multiplex.246
13.1.2 Nonsystemic (Isolated) Peripheral Nervous System
Vasculitis (NSVN).246
13.1.3 Primary Systemic Vasculitis.246
13.1.4 Other Vasculitides.248
13.2 Pathology.249
13.2.1 General Considerations: Sensitivity of Biopsy.249
13.2.2 Some Pathological Considerations.249
13.2.3 Electron Microscopy.252
13.2.4 Immunohistochemistry.252
13.3 Pathogenesis.253
13.3.1 Significance of Size of Involved Vessels.254
13.3.2 Significance of Inflammatory Cell Types.255
13.3.3 Other Elements of Differential Diagnosis.264
13.4 Lymphomatoid Granulomatosis.264
References.268
14 Dysproteinemic Neuropathies.273
14.1 Neuropathy Associated with Paraproteinemia.273
14.1.1 Clinical Manifestations.273
14.1.2 Pathology.275
14.1.3 Pathogenesis.283
14.1.4 Differential Diagnosis.285
14.2 Cryoglobulinemic Neuropathy.288
14.2.1 Clinical Manifestations.288
14.2.2 Pathology.288
14.2.3 Pathogenesis.289
References.289
15 Amyloid Neuropathy.295
15.1 Clinical Manifestations.295
15.1.1 Primary Amyloidosis.295
15.1.2 Hereditary Amyloid Neuropathies.296
15.1.3 Transthyretin.296
15.1.4 Apolipoprotein Al.296
15.1.5 Gelsolin.296
15.1.6 "Sporadic" Amyloid Neuropathy.297
15.1.7 Clinical Features.297
15.1.8 Treatment.297
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15.2 Pathology.298
15.2.1 Utility of Nerve Biopsy.298
15.2.2 General Considerations.298
15.2.3 Light Microscopy.299
15.2.4 Electron Microscopy.300
15.2.5 Immunohistochemistry.300
15.3 Pathogenesis.305
15.4 Differential Diagnosis.306
References.307
16 Neuropathy Associated with Neoplasia.311
16.1 Paraneoplastic Neuropathy.311
16.1.1 Paraneoplastic Subacute Sensory Neuropathy (SSN).311
16.1.2 Paraneoplastic Sensorimotor Neuropathy.314
16.1.3 Other Associations Between Neuropathy and Malignancy.316
16.1.4 Differential Diagnosis.316
16.2 Neuropathy Due to Neoplastic Infiltration.317
16.2.1 Lymphomatous Neuropathy.317
16.2.2 Leukemic Infiltration of the Nerve.318
16.2.3 Multiple Myeloma.323
16.2.4 Differential Diagnosis of Infiltrative Neuropathy.325
16.3 Castleman Disease.325
16.3.1 Clinical Manifestations.325
16.3.2 Pathology.325
16.3.3 Pathogenesis.326
16.4 Angioimmunoblastic T-Cell Lymphoma.326
References.327
17 Neuropathy Associated with Endocrine and Metabolic Disease.331
17.1 Diabetic Neuropathy.331
17.1.1 Clinical Manifestations.331
17.1.2 Pathology.332
17.1.3 Pathogenesis.341
17.2 Neuropathy in Thyroid Disease.344
17.2.1 Clinical Manifestations.344
17.2.2 Pathology.344
17.2.3 Pathophysiology.344
17.2.4 Neuropathy Associated with Hyperthyroidism.344
17.3 Neuropathy in Acromegaly.344
17.3.1 Clinical Manifestations.344
17.3.2 Pathology.345
17.3.3 Pathogenesis.345
17.4 Uremic Neuropathy.345
17.4.1 Clinical Manifestations.345
17.4.2 Pathology.345
17.4.3 Pathogenesis.346
17.5 Neuropathy Associated with Liver Disease.346
17.6 Neuropathy Due to Vitamin Deficiency.346
17.6.1 Thiamine (B0 Deficiency.346
17.6.2 Pyridoxine (B6) Deficiency and Excess.347
17.6.3 Cobalamin (B ,2) Deficiency.347
17.6.4 Tocopherol (Vitamin E) Deficiency.348
17.6.5 Folate Deficiency.348
17.7 Alcoholic Neuropathy.348
17.7.1 Clinical Manifestations.348
17.7.2 Pathology.348
17.7.3 Pathogenesis.349
References.350
18 Toxic Neuropathies. .355
18.1 General Aspects of Toxic Neuropathy.355
18.2 Amiodarone.357
18.2.1 Clinical Manifestations.357
18.2.2 Pathology.359
18.2.3 Pathogenesis.360
18.2.4 Differential Diagnosis.360
18.3 Disulfiram Neuropathy.362
18.3.1 Clinical Manifestations.362
18.3.2 Pathology.363
18.3.3 Pathogenesis.363
18.4 Chemotherapy-Induced Peripheral Neuropathies (CIPN).364
18.5 Misonidazole Neuropathy.364
18.6 Vincristine.367
18.6.1 Clinical Manifestations.367
18.6.2 Pathology.367
18.6.3 Pathogenesis.367
18.7 Hexacarbons.368
18.7.1 Clinical Manifestations.368
18.7.2 Pathology.368
18.7.3 Pathogenesis.368
18.8 Lead.368
18.8.1 Clinical Manifestations.368
18.8.2 Pathology.369
18.8.3 Pathophysiology.369
18.9 Epidemic Toxic Inflammatory Neuropathy.369
18.9.1 Eosinophilia Myalgia Syndrome.369
18.9.2 Toxic Oil Syndrome.370
18.9.3 Pathogenesis.370
18.10 Differential Diagnosis of Toxic Neuropathies.370
18.11 Drug Interactions.370
References.371
19 Genetically Determined Neuropathies.375
19.1 Charcot-Marie-Tooth and Cognate Disorders.375
19.2 CMT-1.376
19.2.1 Clinical Manifestations.376
19.2.2 Pathology.377
19.2.3 Pathogenesis.383
19.2.4 X-Linked CMT.384
19.2.5 Differential Diagnosis.384
19.3 Hereditary Neuropathy with Pressure Palsies.385
19.3.1 Clinical Manifestations.385
19.3.2 Pathology.386
19.3.3 Pathogenesis. .391
19.3.4 Differential Diagnosis.391
19.3.5 Inherited Recurrent Brachial Plexus Neuropathy
(Hereditary Neuralgic Amyotrophy).392
19.4 CMT-2.393
19.4.1 Clinical Manifestations.393
19.4.2 Pathology.393
19.4.3 Pathogenesis.394
19.4.4 Differential Diagnosis.394
19.5 Autosomal Dominant Intermediate CMT.394
19.6 CMT-Associated Demyelinating Neuropathies of Early Onset.398
19.6.1 Light Microscopy.398
19.6.2 Electron Microscopy.398
19.6.3 Pathogenesis.399
19.6.4 CMT Type III with Basal Lamina Onion Bulbs
(CMT-3 BLOB).399
19.6.5 CMT-1 with Basal Lamina Onion Bulbs.400
19.6.6 CMT-3 with Amyelination.402
19.6.7 Reconsideration of the Classification.403
19.7 CMT-4 (Charcot-Marie-Tooth Type 4).403
19.8 Hereditary Sensory Neuropathies.405
19.9 Peripheral Neuropathy Associated with Hereditary Ataxias.406
19.9.1 Friedreich's Ataxia.406
19.9.2 Non-Friedreich's Inherited Spinocerebellar/Cerebellar
Degenerations.407
19.9.3 Abetalipoproteinemia (Bassen-Kornzweig Disease).408
19.9.4 Chediak-Higashi Syndrome.408
19.10 Giant Axonal Neuropathy.408
19.10.1 Clinical Manifestations.408
19.10.2 Pathology.409
19.10.3 Pathogenesis.412
19.10.4 Differential Diagnosis.413
19.11 Refsum Disease (CMT-4).413
19.11.1 Clinical Manifestations.413
19.11.2 Pathology.413
19.11.3 Pathogenesis.414
19.12 Peripheral Neuropathy in Diseases with Defective DNA
Repair Mechanisms.414
19.12.1 Cockayne Syndrome.414
19.12.2 Xeroderma Pigmentosum (XP).415
19.12.3 Ataxia Telangiectasia.415
19.13 Neuropathy with Defective Porphyrin Metabolism.415
19.13.1 Clinical Manifestations.415
19.13.2 Pathology.416
19.13.3 Pathogenesis.417
19.14 Other Genetically Determined Neuropathies.417
19.14.1 Infantile Neuroaxonal Dystrophy.417
19.14.2 The Neuropathy of Oxalosis.418
19.14.3 Peripheral Nerve Changes in Myotonic Dystrophy.419
References.420
20 Storage Diseases.429
20.1 The Sphingolipidoses.429
20.1.1 The Metachromatic Leukodystrophies.429
20.1.2 Globoid Cell Leukodystrophy (Krabbe Disease).436
20.1.3 Fabry Disease.437
20.1.4 Niemann-Pick Disease.444
20.1.5 Färber Disease (FD, Lipogranulomatosis).448
20 1 6 Other Snhinvolinidoses.449
20.2 Adrenoleukodystrophy.451
20.2.1 Clinical Manifestations.451
20.2.2 Pathology.451
20.2.3 Pathogenesis.452
20.3 Neuronal Ceroid Lipofuscinoses (Batten-Kufs Disease).454
20.3.1 Clinical Manifestations.454
20.3.2 Pathology.454
20.4 Tangier Disease (Analphalipoproteinemia).457
20.4.1 Clinical Manifestations.457
20.4.2 Pathology.458
20.4.3 Pathogenesis.459
20.5 Cerebrotendinous Xanthomatosis (Cholestanosis).459
20.5.1 Clinical Manifestations.459
20.5.2 Pathology.459
20.5.3 Pathogenesis.460
20.6 Other Storage Diseases.460
20.6.1 The Mucopolysaccharidoses.460
20.6.2 Glycogen Storage Diseases.460
20.6.3 Sialidosis.461
20.6.4 Wolman Disease.461
20.7 Aspects of Differential Diagnosis in the Storage Diseases.461
References.462
21 Unclassified Neuropathies and Mimics.469
21.1 Neuropathy in Mitochondrial Diseases.469
21.1.1 Clinical Manifestations.469
21.1.2 Pathology.470
21.2 Adult Polyglucosan Body Disease.472
21.2.1 Clinical Manifestations.472
21.2.2 Pathology.472
21.2.3 Pathogenesis.472
21.2.4 Differential Diagnosis.474
21.3 Sensory Neuropathy Syndrome.474
21.3.1 Clinical Manifestations.474
21.3.2 Pathology.475
21.3.3 Pathogenesis.475
21.4 Neuropathy in the Hypereosinophilic Syndrome.475
21.4.1 Clinical Manifestations.475
21.4.2 Pathology.475
21.4.3 Pathogenesis.476
21.5 Motor Neuron Diseases.476
21.5.1 Amyotrophic Lateral Sclerosis.476
21.5.2 Other Motor Neuron Diseases. 476
21.6 Critical Illness Polyneuropathy. 476
21.7 Multiple Symmetrical Lipomatosis (Madelung Disease). 477
21.8 Traumatic Injuries. 477
21.9 Perineurioma. 481
References. 484 |
| any_adam_object | 1 |
| author | Bilbao, Juan M. 1938- Schmidt, Robert E. |
| author_GND | (DE-588)173015794 |
| author_facet | Bilbao, Juan M. 1938- Schmidt, Robert E. |
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| discipline | Medizin |
| edition | 2. ed. |
| format | Book |
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| id | DE-604.BV043228879 |
| illustrated | Illustrated |
| indexdate | 2024-08-14T00:53:47Z |
| institution | BVB |
| isbn | 9783319073101 |
| language | English |
| lccn | 2014946574 |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-028651520 |
| oclc_num | 903280068 |
| open_access_boolean | |
| owner | DE-20 |
| owner_facet | DE-20 |
| physical | XXI, 486 S. Ill., graf. Darst. 29 cm |
| publishDate | 2015 |
| publishDateSearch | 2015 |
| publishDateSort | 2015 |
| publisher | Springer |
| record_format | marc |
| series2 | Pathology |
| spelling | Bilbao, Juan M. 1938- Verfasser (DE-588)173015794 aut Biopsy diagnosis of peripheral neuropathy Juan M. Bilbao ; Robert E. Schmidt 2. ed. Cham ; Heidelberg ; New York ; Dordrecht ; London Springer 2015 XXI, 486 S. Ill., graf. Darst. 29 cm txt rdacontent n rdamedia nc rdacarrier Pathology Literaturangaben Medizin Medicine Neurosciences Neurology Neurosurgery Medicine & Public Health Biopsie (DE-588)4006894-8 gnd rswk-swf Krankheit (DE-588)4032844-2 gnd rswk-swf Peripheres Nervensystem (DE-588)4173794-5 gnd rswk-swf Peripheres Nervensystem (DE-588)4173794-5 s Krankheit (DE-588)4032844-2 s Biopsie (DE-588)4006894-8 s DE-604 Schmidt, Robert E. Verfasser aut Erscheint auch als Online-Ausgabe Biopsy Diagnosis of Peripheral Neuropathy 1. Aufl. im Verl. Butterworth-Heinemann ersch. Biopsy diagnosis of peripheral neuropathy V:DE-576;X:springer image/jpeg http://swbplus.bsz-bw.de/bsz424244470cov.htm Cover HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=028651520&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Bilbao, Juan M. 1938- Schmidt, Robert E. Biopsy diagnosis of peripheral neuropathy Medizin Medicine Neurosciences Neurology Neurosurgery Pathology Medicine & Public Health Biopsie (DE-588)4006894-8 gnd Krankheit (DE-588)4032844-2 gnd Peripheres Nervensystem (DE-588)4173794-5 gnd |
| subject_GND | (DE-588)4006894-8 (DE-588)4032844-2 (DE-588)4173794-5 |
| title | Biopsy diagnosis of peripheral neuropathy |
| title_auth | Biopsy diagnosis of peripheral neuropathy |
| title_exact_search | Biopsy diagnosis of peripheral neuropathy |
| title_full | Biopsy diagnosis of peripheral neuropathy Juan M. Bilbao ; Robert E. Schmidt |
| title_fullStr | Biopsy diagnosis of peripheral neuropathy Juan M. Bilbao ; Robert E. Schmidt |
| title_full_unstemmed | Biopsy diagnosis of peripheral neuropathy Juan M. Bilbao ; Robert E. Schmidt |
| title_old | Biopsy diagnosis of peripheral neuropathy |
| title_short | Biopsy diagnosis of peripheral neuropathy |
| title_sort | biopsy diagnosis of peripheral neuropathy |
| topic | Medizin Medicine Neurosciences Neurology Neurosurgery Pathology Medicine & Public Health Biopsie (DE-588)4006894-8 gnd Krankheit (DE-588)4032844-2 gnd Peripheres Nervensystem (DE-588)4173794-5 gnd |
| topic_facet | Medizin Medicine Neurosciences Neurology Neurosurgery Pathology Medicine & Public Health Biopsie Krankheit Peripheres Nervensystem |
| url | http://swbplus.bsz-bw.de/bsz424244470cov.htm http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=028651520&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
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