Simulations in medicine: pre-clinical and clinical applications
Gespeichert in:
| Weitere Verfasser: | |
|---|---|
| Format: | Buch |
| Sprache: | English |
| Veröffentlicht: |
Berlin ; Boston
de Gruyter
[2015]
|
| Schlagworte: | |
| Online-Zugang: | Inhaltstext Inhaltsverzeichnis |
| Beschreibung: | XVII, 331 Seiten 247 Illustrationen, 5 Diagramme |
| ISBN: | 3110406268 9783110406269 |
Internformat
MARC
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| 245 | 1 | 0 | |a Simulations in medicine |b pre-clinical and clinical applications |c Irena Roterman-Konieczna (ed.) |
| 264 | 1 | |a Berlin ; Boston |b de Gruyter |c [2015] | |
| 264 | 4 | |c © 2015 | |
| 300 | |a XVII, 331 Seiten |b 247 Illustrationen, 5 Diagramme | ||
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Datensatz im Suchindex
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CONTENTS
PREFACE * V
LIST OF AUTHORS XV
PART I: MOLECULAR
LEVEL
MONIKA PIWOWAR AND WIKTOR JURKOWSKI
1 SELECTED ASPECTS OF BIOLOGICAL
NETWORK ANALYSIS * 3
1.1 INTRODUCTION 3
1.2 SELECTED BIOLOGICAL DATABASES * 5
1.2.1 CASE STUDY: GENE EXPRESSION OMNIBUS 6
1.2.2 REGULONDB 9
1.3 TYPES OF BIOLOGICAL NETWORKS 10
1.3.1 RELATIONS BETWEEN MOLECULES AND TYPES OF NETWORKS 10
1.3.2 BIOCHEMICAL PATHWAYS 12
1.4 NETWORK DEVELOPMENT MODELS *14
1.4.1 SELECTED TOOLS FOR ASSEMBLING NETWORKS ON THE BASIS
OF GENE EXPRESSION DATA *14
1.4.2 SELECTED TOOLS FOR RECONSTRUCTION OF NETWORKS
VIA LITERATURE MINING 15
1.5 NETWORK ANALYSIS 16
1.5.1 SELECTED TOOLS 17
1.5.2 CYTOSCAPE ANALYSIS EXAMPLES 23
1.6 SUMMARY 25
PART II: CELLULAR LEVEL
JAKUB WACH,
MARIAN BUBAK, PIOTR NOWAKOWSKI, IRENA ROTERMAN, LESZEK KONIECZNY,
AND KATARZYNA CHTOPAS
2 NEGATIVE FEEDBACK INHIBITION
- FUNDAMENTAL BIOLOGICAL
REGULATION
IN CELLS
AND ORGANISMS * 31
2.1 NEGATIVE FEEDBACK-BASED SYSTEMS SIMULATIONS 41
2.1.1 INTRODUCTION 41
2.1.2 GLOSSARY OF TERMS 41
2.1.3 SOFTWARE MODEL 42
2.1.4 APPLICATION MANUAL 45
2.1.5 OS MODEL EXAMPLE 50
2.1.6 SIMULATION ALGORITHM 52
HTTP://D-NB.INFO/1066332819
VIII
** CONTENTS
IRENA ROTERMAN-KONIECZNA
3 INFORMATION - A TOOL TO INTERPRET THE BIOLOGICAL
PHENOMENA * 57
PART III:
ORGAN LEVEL
ANNA SOCHOCKA AND TOMASZ KAWA
4 THE VIRTUAL
HEART 65
MARC EBNER AND STUART HAMEROFF
5 MODELING
FIGURE/GROUND SEPARATION WITH
SPIKING
NEURONS * 77
5.1 INTRODUCTION * 77
5.2 FIGURE/GROUND SEPARATION 79
5.3 SPIKING NEURAL NETWORKS 81
5.4 LATERAL CONNECTIONS VIA GAP JUNCTIONS 82
5.5 SIMULATION OF A SHEET OF LATERALLY CONNECTED NEURONS 84
5.6 BASIS OF OUR MODEL 91
5.7 CONCLUSION 92
PART IV:
WHOLE BODY
LEVEL
RYSZARD TADEUSIEWICZ
6 SIMULATION-BASED ANALYSIS OF MUSCULOSKELETAL SYSTEM
PROPERTIES *
6.1 INTRODUCTION 99
6.2 COMPONENTS OF A MOTION SIMULATION MODEL 101
6.2.1 SIMULATING THE SKELETON 102
6.2.2 BONE MODEL SIMULATIONS 105
6.2.3 MUSCLE MODELS 110
6.2.4 VELOCITY-DEPENDENT SIMULATIONS OFTHE MUSCLE MODEL 116
6.3 SUMMARY 118
6.4 SIMULATION SOFTWARE AVAILABLE FOR DOWNLOAD 118
PART V:
DIAGNOSTICS PROCEDURE
ANDRZEJ A. KONONOWICZ AND INGA HEGE
7 THE WORLD OF VIRTUAL PATIENTS 121
7.1 INTRODUCTION 121
7.2 WHAT ARE VIRTUAL PATIENTS? *121
7.3 TYPES OF VIRTUAL PATIENT 122
7.4 THE MOTIVATION BEHIND VIRTUAL PATIENTS 125
CONTENTS *
IX
7.5 THEORETICAL UNDERPINNINGS OF VIRTUAL PATIENTS 125
7.5.1 EXPERIENTIAL LEARNING THEORY 126
7.5.2 THEORY OF CLINICAL REASONING 127
7.6 THE TECHNOLOGY BEHIND VIRTUAL PATIENTS 128
7.6.1 VIRTUAL PATIENT SYSTEMS 129
7.6.2 COMPONENTS OF VIRTUAL PATIENTS 130
7.6.3 STANDARDS 132
7.7 HOW TO USE
VIRTUAL PATIENTS? 132
7.7.1 PREPARATION FOR OR FOLLOW-UP OF FACE-TO-FACE TEACHING 133
7.7.2 INTEGRATION INTO A FACE-TO-FACE SESSION 133
7.7.3 ASSESSMENT 133
7.7.4 LEARNING-BY-TEACHING APPROACH 134
7.8 THE FUTURE OF VIRTUAL PATIENTS *134
DICK DAVIES, PEREGRINA ARCIAGA,
PARVATI DEV, AND WM LEROY HEINRICHS
8 INTERACTIVE VIRTUAL
PATIENTS
IN IMMERSIVE CLINICAL
ENVIRONMENTS:
THE POTENTIAL
FOR LEARNING 139
8.1 INTRODUCTION 139
8.2 WHAT ARE VIRTUAL WORLDS? 140
8.3 IMMERSIVE CLINICAL ENVIRONMENTS (VIRTUAL CLINICAL WORLDS) 141
8.4 VIRTUAL PATIENTS 141
8.5 INTERACTIVE VIRTUAL PATIENTS IN IMMERSIVE CLINICAL ENVIRONMENTS *143
8.6 CASE STUDY: USING IMMERSIVE CLINICAL ENVIRONMENTS FOR
INTER-PROFESSIONAL EDUCATION AT CHARLES R. DREW UNIVERSITY
OF MEDICINE 144
8.6.1 INTRODUCTION TO CASE STUDY 144
8.6.2 THE CASE STUDY 145
8.6.3 ASSESSMENT 158
8.6.4 SUMMARY AND LESSONS LEARNED 160
8.7 THE POTENTIAL FOR LEARNING *161
8.7.1 WHY CHOOSE IMMERSIVE CLINICAL ENVIRONMENTS? 161
8.7.2 DECIDE 164
8.7.3 DESIGN 166
8.7.4 DEVELOP 167
8.7.5 DEPLOY 172
8.8 CONCLUSION: "LEARNING BY DOING. TOGETHER" 173
JOANNA JAWOREK-KORJAKOWSKA AND RYSZARD TADEUSIEWICZ
9 MELANOMA THICKNESS PREDICTION
*179
9.1 INTRODUCTION 179
9.2 MOTIVATION 180
9.3 CLINICAL DEFINITION AND IMPORTANCE *181
X
* CONTENTS
9.4 ALGORITHM FOR THE DETERMINATION OF MELANOMA THICKNESS *184
9.5 MELANOMA THICKNESS SIMULATIONS 187
9.6 CONCLUSIONS 192
PART VI:
THERAPY
RYSZARD TADEUSIEWICZ
10 SIMULATING
CANCER CHEMOTHERAPY *197
10.1 SIMULATING UNTREATED CANCER *197
10.2 ENHANCED MODEL OF UNTREATED CANCER 200
10.3 SIMULATING CHEMOTHERAPY * 202
10.4 SIMULATION SOFTWARE AVAILABLE FOR THE READER * 206
PIOTR DUDEK AND JACEK CIESLIK
11 INTRODUCTION TO REVERSE
ENGINEERING AND
RAPID PROTOTYPING
IN MEDICAL
APPLICATIONS 207
11.1 INTRODUCTION 207
11.2 REVERSE ENGINEERING 207
11.2.1 PHASE ONE - INPUTS OF MEDICAL RE 209
11.2.2 PHASE TWO
- DATA ACQUISITION 210
11.2.3 PHASE THREE
- DATA PROCESSING * 212
11.2.4 PHASE FOUR - BIOMEDICAL APPLICATIONS 214
11.3 SOFTWARE FOR MEDICAL RE 215
11.3.1 MIMICS INNOVATION SUITE 215
11.3.2 SIMPLEWARE SCANIP 216
11.3.3 3D-DOCTOR 217
11.3.4 AMIRA 217
11.3.5 OTHER SOFTWARE FOR 3D MODEL RECONSTRUCTION 218
11.3.6 RE AND DIMENSIONAL INSPECTION 219
11.3.7 FREEFORM MODELING 219
11.3.8 FEA SIMULATION AND CAD/CAM SYSTEMS 219
11.4 METHODS OF RAPID PROTOTYPING FOR MEDICAL APPLICATIONS-
ADDITIVE MANUFACTURING 220
11.4.1 LIQUID-BASED RPTECHNOLOGY 222
11.4.2 STEREOLITHOGRAPHY (SLA) 222
11.4.3 POLYMER PRINTING AND JETTING 223
11.4.4 DIGITAL LIGHT PROCESSING (DLP) 224
11.4.5 SOLID SHEET MATERIALS 225
11.4.6 FUSED DEPOSITION MODELING (FDM) 226
11.4.7 SELECTIVE LASER SINTERING (SLS) 227
11.4.8 SELECTIVE LASER
MELTING (SLM) 227
CONTENTS *
XI
11.4.9 ELECTRON BEAM MELTING (EBM) 228
11.4.10 TISSUE ENGINEERING 229
11.5 CASE STUDIES * 230
11.5.1 ONE-STAGE PELVIC TUMOR RECONSTRUCTION 230
11.5.2 ORBITAL RECONSTRUCTION FOLLOWING BLOWOUT FRACTURE 232
11.6 SUMMARY 233
ZDZISLAW WISNIOWSKI, JAKUB DQBROS, AND JACEK DYGUT
12 COMPUTER SIMULATIONS IN SURGICAL EDUCATION 235
12.1 INTRODUCTION 235
12.2 OVERVIEW OF APPLICATIONS 235
12.2.1 GRAY'S ANATOMY STUDENT EDITION, SURGICAL ANATOMY - STUDENT
EDITION,
DIGITAL EDITIONS OF ANATOMY TEXTBOOKS FOR THE IOS
(FREE)
AND ANDROID (PAID) * 236
12.2.2 ESSENTIAL SKELETON 4, DENTAL PATIENT EDUCATION LITE, 3D4MEDICAL
IMAGES
AND ANIMATIONS, FREE EDUCATIONAL SOFTWARE BY 3D4MEDICAL.COM,
AVAILABLE FOR IOS, ANDROID (ESSENTIAL SKELETON 3 - EARLIER VERSION;
PAID EDITIONS OF ESSENTIAL ANATOMY 3 AND IMUSCLE 2) 236
12.2.3 SPINEDECIDE - AN EXAMPLE OF POINT OF CARE PATIENT EDUCATION
FOR HEALTHCARE PROFESSIONALS, AVAILABLE FOR IOS 239
12.2.4 ISURF BRAINVIEW - VIRTUAL GUIDE TO THE HUMAN BRAIN,
AVAILABLE FOR IOS * 240
12.2.5 MONSTER ANATOMY LITE - KNEE - ORTHOPEDIC GUIDE, AVAILABLE FOR IOS
(MONSTER MINDS MEDIA) 241
12.2.6 AO SURGERY REFERENCE - ORTHOPEDIC GUIDEBOOK FOR DIAGNOSIS
AND TRAUMA TREATMENT, AVAILABLE FOR IOS AND ANDROID * 243
12.2.7 IORTHO+ - EDUCATIONAL AID FOR REHABILITATIONISTS, AVAILABLE FOR
IOS
AND ANDROID 245
12.2.8 DRAWMD - BASED ON GENERAL
SURGERY AND THORACIC SURGERY
BY VISIBLE HEALTH INC., AVAILABLE FOR IOS 247
12.2.9 MEDTUBE, AVAILABLE FOR IOS AND ANDROID 250
12.3 SPECIALIZED APPLICATIONS 254
12.3.1 APPLICATION DESCRIPTION 255
12.4 SIMULATORS 262
12.4.1 SELECTED EXAMPLES OF SURGICAL SIMULATORS 263
12.5 SUMMARY 265
XII
CONTENTS
PART VII:
SUPPORT OF THERAPY
TUKASZ CZEKIERDA, ANDRZEJ GACKOWSKI, MAREK KONIECZNY, FILIP MALAWSKI,
KORNEL SKATKOWSKI, TOMASZ SZYDTO, AND KRZYSZTOF ZIELINSKI
13 FROM TELEMEDIDNE TO MODELING AND
PROACTIVE MEDICINE
* 271
13.1 INTRODUCTION 271
13.2 ICT-DRIVEN TRANSFORMATION IN HEALTHCARE 272
13.2.1 OVERVIEW OF TELEMEDIDNE 272
13.2.2 TRADITIONAL MODEL OF HEALTHCARE SUPPORTED BY TELEMEDICINE 273
13.2.3 MODELING AS KNOWLEDGE REPRESENTATION IN MEDICINE 274
13.2.A TOWARDS A PERSONALIZED AND PROACTIVE APPROACH IN MEDICINE 275
13.2.5 MODEL OF PROACTIVE HEALTHCARE 277
13.3 COMPUTATIONAL METHODS FOR MODELS DEVELOPMENT * 278
13.3.1 COMPUTATIONAL METHODS FOR IMAGING DATA 281
13.3.2 COMPUTATIONAL METHODS FOR PARAMETRIC DATA 282
13.4 TELECARE - TELEMONITORING FRAMEWORK 282
13.4.1 OVERVIEW 282
13.4.2 CONTRIBUTION TO THE MODEL-BASED PROACTIVE MEDICINE CONCEPT 284
13.4.3 CASE STUDY 286
13.5 TELEDICOM - SYSTEM FOR REMOTE INTERACTIVE CONSULTATIONS 287
13.5.1 OVERVIEW 287
13.5.2 CONTRIBUTION TO THE MODEL-BASED PROACTIVE MEDICINE CONCEPT * 288
13.6 CONCLUSIONS 290
14 SERIOUS GAMES
IN MEDICINE 295
PAWEL W^GRZYN
14.1 SERIOUS GAMES FOR HEALTH - VIDEO GAMES AND HEALTH ISSUES 295
14.1.1 INTRODUCTION 295
14.1.2 PREVIOUS SURVEYS 296
14.1.3 EVIDENCE REVIEW 299
14.1.4 CONCLUSIONS 310
EWA GRABSKA
14.2 SERIOUS GAME GRAPHIC DESIGN BASED ON UNDERSTANDING OF A NEW MODEL
OF VISUAL PERCEPTION - COMPUTER GRAPHICS 318
14.2.1 INTRODUCTION 318
14.2.2 A NEW MODEL OF PERCEPTION FOR VISUAL COMMUNICATION 319
14.2.3 VISIBILITY ENHANCEMENT WITH THE USE OF ANIMATION 322
14.2.4 CONCLUSION 323
IRENA ROTERMAN-KONIECZNA
14.3 SERIOUS GAMING IN MEDICINE 324
14.3.1 THERAPEUTIC SUPPORT FOR CHILDREN 324
14.3.2 THERAPEUTIC SUPPORT FOR THE ELDERLY 327
INDEX * 329 |
| any_adam_object | 1 |
| author2 | Roterman-Konieczna, Irena |
| author2_role | edt |
| author2_variant | i r k irk |
| author_GND | (DE-588)1028535678 |
| author_facet | Roterman-Konieczna, Irena |
| building | Verbundindex |
| bvnumber | BV043192340 |
| classification_tum | MED 371f |
| ctrlnum | (OCoLC)903392650 (DE-599)DNB1066332819 |
| dewey-full | 610.11 |
| dewey-hundreds | 600 - Technology (Applied sciences) |
| dewey-ones | 610 - Medicine and health |
| dewey-raw | 610.11 |
| dewey-search | 610.11 |
| dewey-sort | 3610.11 |
| dewey-tens | 610 - Medicine and health |
| discipline | Medizintechnik Medizin |
| format | Book |
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| id | DE-604.BV043192340 |
| illustrated | Illustrated |
| indexdate | 2024-09-10T01:57:32Z |
| institution | BVB |
| isbn | 3110406268 9783110406269 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-028615938 |
| oclc_num | 903392650 |
| open_access_boolean | |
| owner | DE-578 DE-91 DE-BY-TUM |
| owner_facet | DE-578 DE-91 DE-BY-TUM |
| physical | XVII, 331 Seiten 247 Illustrationen, 5 Diagramme |
| publishDate | 2015 |
| publishDateSearch | 2015 |
| publishDateSort | 2015 |
| publisher | de Gruyter |
| record_format | marc |
| spelling | Simulations in medicine pre-clinical and clinical applications Irena Roterman-Konieczna (ed.) Berlin ; Boston de Gruyter [2015] © 2015 XVII, 331 Seiten 247 Illustrationen, 5 Diagramme txt rdacontent n rdamedia nc rdacarrier Medizinstudium (DE-588)4038291-6 gnd rswk-swf Diagnostik (DE-588)4113303-1 gnd rswk-swf Biologisches System (DE-588)4122930-7 gnd rswk-swf Medizin (DE-588)4038243-6 gnd rswk-swf Therapie (DE-588)4059798-2 gnd rswk-swf Computersimulation (DE-588)4148259-1 gnd rswk-swf Biologisches System (DE-588)4122930-7 s Computersimulation (DE-588)4148259-1 s Medizinstudium (DE-588)4038291-6 s DE-604 Medizin (DE-588)4038243-6 s Diagnostik (DE-588)4113303-1 s Therapie (DE-588)4059798-2 s 1\p DE-604 Roterman-Konieczna, Irena (DE-588)1028535678 edt Erscheint auch als Online-Ausgabe, EPUB 978-3-11-040644-3 Erscheint auch als Online-Ausgabe, PDF 978-3-11-040634-4 X:MVB text/html http://deposit.dnb.de/cgi-bin/dokserv?id=5145908&prov=M&dok_var=1&dok_ext=htm Inhaltstext DNB Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=028615938&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis 1\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk |
| spellingShingle | Simulations in medicine pre-clinical and clinical applications Medizinstudium (DE-588)4038291-6 gnd Diagnostik (DE-588)4113303-1 gnd Biologisches System (DE-588)4122930-7 gnd Medizin (DE-588)4038243-6 gnd Therapie (DE-588)4059798-2 gnd Computersimulation (DE-588)4148259-1 gnd |
| subject_GND | (DE-588)4038291-6 (DE-588)4113303-1 (DE-588)4122930-7 (DE-588)4038243-6 (DE-588)4059798-2 (DE-588)4148259-1 |
| title | Simulations in medicine pre-clinical and clinical applications |
| title_auth | Simulations in medicine pre-clinical and clinical applications |
| title_exact_search | Simulations in medicine pre-clinical and clinical applications |
| title_full | Simulations in medicine pre-clinical and clinical applications Irena Roterman-Konieczna (ed.) |
| title_fullStr | Simulations in medicine pre-clinical and clinical applications Irena Roterman-Konieczna (ed.) |
| title_full_unstemmed | Simulations in medicine pre-clinical and clinical applications Irena Roterman-Konieczna (ed.) |
| title_short | Simulations in medicine |
| title_sort | simulations in medicine pre clinical and clinical applications |
| title_sub | pre-clinical and clinical applications |
| topic | Medizinstudium (DE-588)4038291-6 gnd Diagnostik (DE-588)4113303-1 gnd Biologisches System (DE-588)4122930-7 gnd Medizin (DE-588)4038243-6 gnd Therapie (DE-588)4059798-2 gnd Computersimulation (DE-588)4148259-1 gnd |
| topic_facet | Medizinstudium Diagnostik Biologisches System Medizin Therapie Computersimulation |
| url | http://deposit.dnb.de/cgi-bin/dokserv?id=5145908&prov=M&dok_var=1&dok_ext=htm http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=028615938&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| work_keys_str_mv | AT rotermankoniecznairena simulationsinmedicinepreclinicalandclinicalapplications |