Seafood and freshwater toxins pharmacology, physiology, and detection (Marcel Dekker, 2000)
Includes bibliographical references and index
Scientists from many disciplines, most but not all of them biological, offer a broad reference for graduate and research pharmacologists, physiologists, biochemists, medical doctors, and food technologists. The original idea was to focus on seafood toxins, but cyanobacterial, or freshwater, toxins were included because of the many similarities between them, and because marine species living close to estuaries can be contaminated with toxins generated upstream. The sections cover general considerations; the epidemiological impact of toxic episodes; paralytic shellfish poisoning; enteric toxic episodes: DSP toxins, pecteno, and yessotoxins; amnesic toxic episodes; non-PSP neurotoxic episodes; palytoxin; freshwater toxins; new toxins and drugs; and economical considerations regarding toxic episodes. Annotation c. Book News, Inc., Portland, OR (booknews.com)
Historic considerations regarding seafood safety -- Diversity of marine and freshwater algal toxins -- Nonneurotoxic toxins -- Neurotoxic toxins -- Calcium channels for exocytosis: functional modulation with toxins -- Ecobiology, classification, and origin -- Chemistry and mechanism of action -- Chemical analysis of PSP toxins -- Biological detection methods -- Paralytic shellfish poisoning (PSP): toxicology and kinetics -- Detection methods for okadaic acid and analogues -- Mechanism of action and toxicology -- Neoplastic activity of DSP toxins: the effects of okadaic acid and related compounds on cell proliferation: tumor promotion or induction of apoptosis? -- Pectenotoxins and yessotoxins: chemistry, toxicology, pharmacology, and analysis -- Ecobiology, clinical symptoms, and mode of action of domoic acid, an amnesic shellfish toxin -- Pharmacology of domoic acid -- Molecular biology of kainate receptors: targets of domoic acid toxicity --
- Chemical and biological detection methods -- Ciguatera toxins: chemistry and detection -- Ciguatera toxins: pharmacology of toxins involved in ciguatera and related fish poisonings -- Ciguatera toxins: toxinology -- Ciguatera toxins: mechanism of action and pharmacology of maitotoxin -- Brevetoxins: chemistry, mechanism of action, and methods of detection -- Chemistry and detection -- Mechanism of action, pharmacology, and toxicology -- Freshwater cyanobacterial neurotoxins: ecobiology, chemistry, and detection -- Freshwater neurotoxins: mechanisms of action, pharmacology, toxicology, and impacts on aquaculture -- Freshwater hepatotoxins: ecobiology and classification -- Freshwater hepatotoxins: chemistry and detection -- Freshwater hepatotoxins: microcystin and nodularin, mechanisms of toxicity and effects on health -- Freshwater hepatotoxins: geographical distribution of toxic cyanobacteria -- New toxins on the horizon -- Marine toxins as a starting point for drugs --
- Incidence of marine toxins on industrial activity -- Remote sensing and computerized mapping for development of harmful algal bloom prediction methods