The dynamic neuron: a comprehensive survey of the neurochemical basis of synaptic plasticity
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Bibliographic Details
Main Author: Smythies, John R., (John Raymond) (Author)
Format: Electronic eBook
Language:English
Published: Cambridge, Mass. MIT Press ©2002
Series:Bradford book
Subjects:
Online Access:FAW01
FAW02
Volltext
Item Description:"A Bradford book."
Includes bibliographical references (pages 107-143) and index
1 - Synaptic biochemistry -- - 2 - Endocytosis and exocytosis -- - 3 - Special proteins -- - 4 - Miscellaneous items -- - 5 - Pharmoacological implications and clinical appications -- - 6 - Conclusions
The traditional model of synapses as fixed structures has been replaced by a dynamic one in which synapses are constantly being deleted and replaced. This book, written by a leading researcher on the neurochemistry of schizophrenia, integrates material from neuroscience and cell biology to provide a comprehensive account of our current knowledge of the neurochemical basis of synaptic plasticity.The book presents the evidence for synaptic plasticity, an account of the dendritic spine and the glutamate synapse with a focus on redox mechanisms, and the biochemical basis of the Hebbian synapse. It discusses the role of endocytosis, special proteins, and local protein synthesis. Additional topics include volume transmission, arachidonic acid signaling, hormonal modulation, and psychological stress. Finally, the book considers pharmacological and clinical implications of current research, particularly with reference to schizophrenia and Alzheimer's disease
Physical Description:1 Online-Ressource (viii, 150 pages)
ISBN:0262194732
0585442592
9780262194730
9780585442594

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