Hemodynamics and mechanobiology of endothelium (World Scientific, 2010)
Includes bibliographical references and index
Ch. 1. Flow and atherosclerosis / Ian Campbell and W. Robert Taylor -- ch. 2. Shear stress-mediated signal transduction / Jun-Ichi Abe [and others] -- ch. 3. Endothelial glycocalyx structure and role in mechanotransduction / John M. Tarbell and Eno E. Ebong -- ch. 4. Role of Kruppel-like factors in shear stress-mediated vasoprotection / Daiji Kawanami [and others] -- ch. 5. Rho family small GTPases in shear stress signaling / Daniel T. Sweet and Ellie Tzima -- ch. 6. Nitric oxide and endothelial mitochondrial function : Implications for ischemia/reperfusion / B.R. Alevriadou, C.I. Jones and R.J. Giedt -- ch. 7. Genomic approaches to endothelial cell phenotyping / Anthony G. Passerini -- ch. 8. Endothelial cell proliferation and differentiation in response to shear stress / Lingfang Zeng, Anna Zampetaki and Qingbo Xu -- ch. 9. Vascular differentiation of stem cells by mechanical forces / Timothy M. Maul, Alejandro Nieponice and David A Vorp -- ch. 10. Tissue engineered blood vessels : From the bench to the bedside and back again (Development of a vascular conduit for use in congenital heart surgery) / Bernard S. Salameh [and others] -- ch. 11. Design implications for endovascular stents and the endothelium / Juan M. Jimenez and Peter F. Davies -- ch. 12. Vascular mimetic microfluidic systems for the study of endothelial activation and leukocyte recruitment in models of atherogenesis / R. Michael Gower and Scott Simon -- ch. 13. Micro shear stress sensors : From in vitro to in vivo assessment of inflammatory responses / Lisong Ai [and others]
The book represents a paradigm shift from the traditional static model of investigation of oxidative biology to the dynamic model of vascular oxidative stress. The investigation of vascular biology and cardiovascular medicine is made possible by the use of fluid dynamics, molecular signaling, genomic approach, tissue engineering, stem cell biology, and microfluidics. This is the first book to target a wide readership from academia to industry and government agencies in the field of cardiovascular diseases