Use of high performance computing in meteorology: proceedings of the Twelfth ECMWF Workshop, Reading, UK, 30 October - 3 November 2006
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| Körperschaft: | |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Singapore
World Scientific
c2007
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| Schlagworte: | |
| Online-Zugang: | FAW01 FAW02 Volltext |
| Beschreibung: | Includes bibliographical references Adult or postnatal stem cells offer life-long cell replacement in tissues and organs, and are thus unavoidable targets of long-term and transient regenerative/epigenetic gene therapy for both inherited and acquired diseases; and effective anticancer therapy. In particular, autologous stem cells have been instrumental to the success of gene therapy, enabling breakthrough endonuclease-boosted gene targeting for gene correction (inherited diseases) or targeted integration of therapeutic transgenes (other disorders).This timely book highlights the pioneering translation of adult pluripotent stem cells as a substitute for tissue-specific stem cells, thereby pinpointing the invaluable potential for stem cell gene therapy applications of autologous cells to contribute to all three germ players. Pathologies are discussed in terms of stem cell repopulation dynamics, with appropriate niches (long-term engraftment) and tissues (cell turnover). Focus is also placed on the increasing number of identified tissue-specific cancer stem cells as the ultimate targets for recurrence-free cancer recovery, and on the development of armed stem cells as tumor-homing vectors for targeted anticancer stem cell gene therapy |
| Beschreibung: | 1 Online-Ressource (viii, 273 p.) |
| ISBN: | 1281928933 9781281928931 9789812775887 9789812775894 9812775889 9812775897 |
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| 245 | 1 | 0 | |a Use of high performance computing in meteorology |b proceedings of the Twelfth ECMWF Workshop, Reading, UK, 30 October - 3 November 2006 |c edited by George Mozdzynski |
| 246 | 1 | 3 | |a Proceedings of the Twelfth ECMWF Workshop |
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| 500 | |a Adult or postnatal stem cells offer life-long cell replacement in tissues and organs, and are thus unavoidable targets of long-term and transient regenerative/epigenetic gene therapy for both inherited and acquired diseases; and effective anticancer therapy. In particular, autologous stem cells have been instrumental to the success of gene therapy, enabling breakthrough endonuclease-boosted gene targeting for gene correction (inherited diseases) or targeted integration of therapeutic transgenes (other disorders).This timely book highlights the pioneering translation of adult pluripotent stem cells as a substitute for tissue-specific stem cells, thereby pinpointing the invaluable potential for stem cell gene therapy applications of autologous cells to contribute to all three germ players. Pathologies are discussed in terms of stem cell repopulation dynamics, with appropriate niches (long-term engraftment) and tissues (cell turnover). Focus is also placed on the increasing number of identified tissue-specific cancer stem cells as the ultimate targets for recurrence-free cancer recovery, and on the development of armed stem cells as tumor-homing vectors for targeted anticancer stem cell gene therapy | ||
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| spelling | ECMWF Workshop on the Use of High Performance Computing in Meteorology < 2006, Reading, Great Britain> Verfasser aut Use of high performance computing in meteorology proceedings of the Twelfth ECMWF Workshop, Reading, UK, 30 October - 3 November 2006 edited by George Mozdzynski Proceedings of the Twelfth ECMWF Workshop Singapore World Scientific c2007 1 Online-Ressource (viii, 273 p.) txt rdacontent c rdamedia cr rdacarrier Includes bibliographical references Adult or postnatal stem cells offer life-long cell replacement in tissues and organs, and are thus unavoidable targets of long-term and transient regenerative/epigenetic gene therapy for both inherited and acquired diseases; and effective anticancer therapy. In particular, autologous stem cells have been instrumental to the success of gene therapy, enabling breakthrough endonuclease-boosted gene targeting for gene correction (inherited diseases) or targeted integration of therapeutic transgenes (other disorders).This timely book highlights the pioneering translation of adult pluripotent stem cells as a substitute for tissue-specific stem cells, thereby pinpointing the invaluable potential for stem cell gene therapy applications of autologous cells to contribute to all three germ players. Pathologies are discussed in terms of stem cell repopulation dynamics, with appropriate niches (long-term engraftment) and tissues (cell turnover). Focus is also placed on the increasing number of identified tissue-specific cancer stem cells as the ultimate targets for recurrence-free cancer recovery, and on the development of armed stem cells as tumor-homing vectors for targeted anticancer stem cell gene therapy SCIENCE / Earth Sciences / Meteorology & Climatology bisacsh Atmospheric physics / Mathematical models / Data processing fast Meteorology / Mathematical models / Data processing fast Parallel processing (Electronic computers) fast Supercomputers fast Datenverarbeitung Geowissenschaften Mathematisches Modell Meteorology Mathematical models Data processing Congresses Atmospheric physics Mathematical models Data processing Congresses Parallel processing (Electronic computers) Congresses Supercomputers Congresses (DE-588)1071861417 Konferenzschrift gnd-content Mozdzynski, George Sonstige oth European Centre for Medium Range Weather Forecasts Sonstige oth http://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&db=nlabk&AN=235978 Aggregator Volltext |
| spellingShingle | Use of high performance computing in meteorology proceedings of the Twelfth ECMWF Workshop, Reading, UK, 30 October - 3 November 2006 SCIENCE / Earth Sciences / Meteorology & Climatology bisacsh Atmospheric physics / Mathematical models / Data processing fast Meteorology / Mathematical models / Data processing fast Parallel processing (Electronic computers) fast Supercomputers fast Datenverarbeitung Geowissenschaften Mathematisches Modell Meteorology Mathematical models Data processing Congresses Atmospheric physics Mathematical models Data processing Congresses Parallel processing (Electronic computers) Congresses Supercomputers Congresses |
| subject_GND | (DE-588)1071861417 |
| title | Use of high performance computing in meteorology proceedings of the Twelfth ECMWF Workshop, Reading, UK, 30 October - 3 November 2006 |
| title_alt | Proceedings of the Twelfth ECMWF Workshop |
| title_auth | Use of high performance computing in meteorology proceedings of the Twelfth ECMWF Workshop, Reading, UK, 30 October - 3 November 2006 |
| title_exact_search | Use of high performance computing in meteorology proceedings of the Twelfth ECMWF Workshop, Reading, UK, 30 October - 3 November 2006 |
| title_full | Use of high performance computing in meteorology proceedings of the Twelfth ECMWF Workshop, Reading, UK, 30 October - 3 November 2006 edited by George Mozdzynski |
| title_fullStr | Use of high performance computing in meteorology proceedings of the Twelfth ECMWF Workshop, Reading, UK, 30 October - 3 November 2006 edited by George Mozdzynski |
| title_full_unstemmed | Use of high performance computing in meteorology proceedings of the Twelfth ECMWF Workshop, Reading, UK, 30 October - 3 November 2006 edited by George Mozdzynski |
| title_short | Use of high performance computing in meteorology |
| title_sort | use of high performance computing in meteorology proceedings of the twelfth ecmwf workshop reading uk 30 october 3 november 2006 |
| title_sub | proceedings of the Twelfth ECMWF Workshop, Reading, UK, 30 October - 3 November 2006 |
| topic | SCIENCE / Earth Sciences / Meteorology & Climatology bisacsh Atmospheric physics / Mathematical models / Data processing fast Meteorology / Mathematical models / Data processing fast Parallel processing (Electronic computers) fast Supercomputers fast Datenverarbeitung Geowissenschaften Mathematisches Modell Meteorology Mathematical models Data processing Congresses Atmospheric physics Mathematical models Data processing Congresses Parallel processing (Electronic computers) Congresses Supercomputers Congresses |
| topic_facet | SCIENCE / Earth Sciences / Meteorology & Climatology Atmospheric physics / Mathematical models / Data processing Meteorology / Mathematical models / Data processing Parallel processing (Electronic computers) Supercomputers Datenverarbeitung Geowissenschaften Mathematisches Modell Meteorology Mathematical models Data processing Congresses Atmospheric physics Mathematical models Data processing Congresses Parallel processing (Electronic computers) Congresses Supercomputers Congresses Konferenzschrift |
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