Toxicity testing strategies to determine needs and priorities (National Academy Press, 1984)
Includes bibliographical references
Toxicity-testing needs in the select universe -- Sample selection -- Operating policies for identification, acquisition, and organization of data -- Data evaluation -- Results -- Setting priorities for toxicity testing -- Design of the priority system -- Briefly following a chemical through an illustrative system -- Detail description of the operation of an illustrative system -- Future development, implementation, and refinement of the system -- Conclusions and recommendations
Prepared at the request of the National Toxicology Program, this landmark report reveals that many chemicals used in pesticides, cosmetics, drugs, food, and commerce have not been sufficiently tested to allow a complete determination of their potential hazards. Given the vast number of chemical substances to which humans are exposed, the authors use a model to show how research priorities for toxicity testing can be set