The oncogene and tumour suppressor gene factsbook:
Gespeichert in:
| 1. Verfasser: | |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
San Diego, Calif.
Academic Press
c1997
|
| Ausgabe: | 2nd ed |
| Schriftenreihe: | Factsbook series
|
| Schlagworte: | |
| Online-Zugang: | FAW01 FAW02 Volltext |
| Beschreibung: | The Second Edition of The Oncogene and Tumour Suppressor Gene FactsBook has been completely revised, updated, and expanded by 60%. The book contains more than 80 entries on oncogenes including JUN, MYC, and RAS, as well as DNA tumour viruses, tumour suppressor genes, including p53, retinoblastoma, BRCA1, BRCA2, VHL, F2FL, and essential material on angiogenesis and metastasis, apoptosis, cell cycle control, and gene therapy. Key Features * Includes much new data on this fast-moving field, including newly discovered oncogenes * Summarizes the clinical association and molecular properties of all known oncogenes and tumor suppression genes * Contains more than 2000 terms for reference and further research * Revised to included signaling pathways, apoptosis, and metastasis The Introductory Chapters: -- Introduction: Identification of Oncogenes. -- Oncogene Activation in Humans. -- Proliferation Control Pathways: Oncoprotein Function. -- Growth Factor-Related Proteins. -- SRC. RAS and RAF. -- Nuclear Oncoproteins. -- ETS. FOS and JUN. MYB. MYC. REL. ERBA. -- Tumour Suppressor Genes: RB1. P53. -- Other Major Tumour Suppressor Genes. -- APC. BRCA1. NF1. VHL. WT1. -- Cell Cycle Control: Cyclin-Dependent Kinase Inhibitors (CDKIs). -- Apoptosis: Tumour Suppressor Genes and Apoptosis. -- DNA Repair. -- Angiogenesis and Metastasis: Angiogenesis. -- Angiogenic Promoters. -- Angiogenic Inhibitors. -- Metastasis: Correlations with Gene Expression. -- Cadherins. -- The Immunoglobulin Superfamily (IgSF), Neural Cell-Adhesion Molecule (NCAM). -- Integrins. -- CD44. -- Matrix Metalloproteinases (MMPS). -- Tissue Inhibitors of Metalloproteinases (TIMPs). -- Cysteine and Aspartic Proteinases and Heparanase. -- NME1 and NME2. -- - The Multi-step Nature of Cancer: Cervical Carcinoma. -- Colorectal Carcinoma. -- Breast Carcinoma. -- Prostate Carcinoma. -- Renal Cell Carcinoma. -- Lung Carcinoma. -- Lymphomas. -- Chronic Myeloid Leukemia. -- Gene Therapy for Cancer: Nucleotide Sequence-Targeted Strategies. -- Tumour Suppressor Gene Therapy. -- Cytokine Gene Therapy and Tumour Vaccination. -- Virally Directed Enzyme Prodrug Therapy (VDEPT). -- Antibody-directed Therapy. -- Tables: -- Oncogenes Transduced by Retroviruses. -- Oncogenes Activated by Retroviral Insertion. -- Oncogenes at Chromosomal Translocations. -- Tumour Suppressor Genes Detected in Human Tumours. -- Functions of Oncoproteins. -- Chromosome Locations of Human Proto-Oncogenes and Tumour Suppressor Genes. -- The Oncogenes: -- - ABL. AKT1 and AKT2. BCL2. BCL3. BCR. CBL. CDK4. CRK. CSFIR/FMS. D Cyclins. DBL. EGFR/ErbB. ELK1. EPH. ERG. ETS1 and ETS2. FGR. FLII. FOS. FOSB. FPS/FES. FRA1 and FRA2. FYN. HCK. HER2/ErbB-2/Neu. HER3/ErbB-3. HER4/ErbB-4. HSTF1/HST2. INT2. JUN. JUNB. JUND. KIT. LCK. LYN. MAS. MAX. MET. Mil. MOS. MYB. MYC. PDGF/Sis. PIM1. RAF. RAS. REL. RET. ROS1. SEA. SKI. SRC. TAL1. THRA/ErbA-1 and THRA2/ErbA-2. TIAM1. TRK. VAV. WNT1. WNT2 and WNT3. YES1. -- Tumour Suppressor Genes: -- APC and MCC. BRCA1 and BRCA2. DCC. DPC4. E2F1. E-cadherin/CDH1. MSH2. MSH3. MSH6/GTBP and MLHL. NF1 and NF2. P53, PTC. -- The Retinoblastoma Gene (RB1). TGFBR1 and TGFBR2. VHL; WT1. -- Cyclin-dependent Kinase Inhibitors: -- INK4A/MTS1/MTS2/CDK41/CDKN2. INK4B/MTS2. -- INK4C and INK4D. KIP1. KIP2. WAF1. -- DNA Tumour Viruses: -- Human Papillomaviruses. -- Epstein-Barr Virus. -- Subject Index Includes bibliographical references and index Sect. 1. The introductory chapters -- Genetic events in cancer delelopment -- Proliferation control pathways -- Tumour suppressor genes -- Cell cycle control -- Apoptosis -- DNA repair -- Angiogenesis and metastasis -- The multistep nature of cancer -- Gene therapy for cancer -- Sect. 2. Tables -- Oncogenes transduced by retroviruses -- Oncogenes activated by retroviral insertion -- Oncogenes at chromosomal translocations -- Tumour suppressor genes detected in human tumours -- Functions of oncoproteins -- Chromosome locations of human proto-oncogenes and tumour -- suppressor genes -- Sect. 3. The oncogenes -- Sect. 4. Tumour suppressor genes -- Sect. 5. Cyclin-dependent kinase inhibitors -- Sect. 6. DNA tumour viruses |
| Beschreibung: | 1 Online-Ressource (xiv, 549 p.) |
| ISBN: | 0080538002 0123445485 9780080538006 9780123445483 |
Internformat
MARC
| LEADER | 00000nmm a2200000zc 4500 | ||
|---|---|---|---|
| 001 | BV043044772 | ||
| 003 | DE-604 | ||
| 005 | 00000000000000.0 | ||
| 007 | cr|uuu---uuuuu | ||
| 008 | 151123s1997 |||| o||u| ||||||eng d | ||
| 020 | |a 0080538002 |c electronic bk. |9 0-08-053800-2 | ||
| 020 | |a 0123445485 |9 0-12-344548-5 | ||
| 020 | |a 9780080538006 |c electronic bk. |9 978-0-08-053800-6 | ||
| 020 | |a 9780123445483 |9 978-0-12-344548-3 | ||
| 035 | |a (OCoLC)162572729 | ||
| 035 | |a (DE-599)BVBBV043044772 | ||
| 040 | |a DE-604 |b ger |e aacr | ||
| 041 | 0 | |a eng | |
| 049 | |a DE-1046 |a DE-1047 | ||
| 082 | 0 | |a 616.99/4071 |2 22 | |
| 100 | 1 | |a Hesketh, Robin |e Verfasser |4 aut | |
| 245 | 1 | 0 | |a The oncogene and tumour suppressor gene factsbook |c Robin Hesketh |
| 250 | |a 2nd ed | ||
| 264 | 1 | |a San Diego, Calif. |b Academic Press |c c1997 | |
| 300 | |a 1 Online-Ressource (xiv, 549 p.) | ||
| 336 | |b txt |2 rdacontent | ||
| 337 | |b c |2 rdamedia | ||
| 338 | |b cr |2 rdacarrier | ||
| 490 | 0 | |a Factsbook series | |
| 500 | |a The Second Edition of The Oncogene and Tumour Suppressor Gene FactsBook has been completely revised, updated, and expanded by 60%. The book contains more than 80 entries on oncogenes including JUN, MYC, and RAS, as well as DNA tumour viruses, tumour suppressor genes, including p53, retinoblastoma, BRCA1, BRCA2, VHL, F2FL, and essential material on angiogenesis and metastasis, apoptosis, cell cycle control, and gene therapy. Key Features * Includes much new data on this fast-moving field, including newly discovered oncogenes * Summarizes the clinical association and molecular properties of all known oncogenes and tumor suppression genes * Contains more than 2000 terms for reference and further research * Revised to included signaling pathways, apoptosis, and metastasis | ||
| 500 | |a The Introductory Chapters: -- Introduction: Identification of Oncogenes. -- Oncogene Activation in Humans. -- Proliferation Control Pathways: Oncoprotein Function. -- Growth Factor-Related Proteins. -- SRC. RAS and RAF. -- Nuclear Oncoproteins. -- ETS. FOS and JUN. MYB. MYC. REL. ERBA. -- Tumour Suppressor Genes: RB1. P53. -- Other Major Tumour Suppressor Genes. -- APC. BRCA1. NF1. VHL. WT1. -- Cell Cycle Control: Cyclin-Dependent Kinase Inhibitors (CDKIs). -- Apoptosis: Tumour Suppressor Genes and Apoptosis. -- DNA Repair. -- Angiogenesis and Metastasis: Angiogenesis. -- Angiogenic Promoters. -- Angiogenic Inhibitors. -- Metastasis: Correlations with Gene Expression. -- Cadherins. -- The Immunoglobulin Superfamily (IgSF), Neural Cell-Adhesion Molecule (NCAM). -- Integrins. -- CD44. -- Matrix Metalloproteinases (MMPS). -- Tissue Inhibitors of Metalloproteinases (TIMPs). -- Cysteine and Aspartic Proteinases and Heparanase. -- NME1 and NME2. -- | ||
| 500 | |a - The Multi-step Nature of Cancer: Cervical Carcinoma. -- Colorectal Carcinoma. -- Breast Carcinoma. -- Prostate Carcinoma. -- Renal Cell Carcinoma. -- Lung Carcinoma. -- Lymphomas. -- Chronic Myeloid Leukemia. -- Gene Therapy for Cancer: Nucleotide Sequence-Targeted Strategies. -- Tumour Suppressor Gene Therapy. -- Cytokine Gene Therapy and Tumour Vaccination. -- Virally Directed Enzyme Prodrug Therapy (VDEPT). -- Antibody-directed Therapy. -- Tables: -- Oncogenes Transduced by Retroviruses. -- Oncogenes Activated by Retroviral Insertion. -- Oncogenes at Chromosomal Translocations. -- Tumour Suppressor Genes Detected in Human Tumours. -- Functions of Oncoproteins. -- Chromosome Locations of Human Proto-Oncogenes and Tumour Suppressor Genes. -- The Oncogenes: -- | ||
| 500 | |a - ABL. AKT1 and AKT2. BCL2. BCL3. BCR. CBL. CDK4. CRK. CSFIR/FMS. D Cyclins. DBL. EGFR/ErbB. ELK1. EPH. ERG. ETS1 and ETS2. FGR. FLII. FOS. FOSB. FPS/FES. FRA1 and FRA2. FYN. HCK. HER2/ErbB-2/Neu. HER3/ErbB-3. HER4/ErbB-4. HSTF1/HST2. INT2. JUN. JUNB. JUND. KIT. LCK. LYN. MAS. MAX. MET. Mil. MOS. MYB. MYC. PDGF/Sis. PIM1. RAF. RAS. REL. RET. ROS1. SEA. SKI. SRC. TAL1. THRA/ErbA-1 and THRA2/ErbA-2. TIAM1. TRK. VAV. WNT1. WNT2 and WNT3. YES1. -- Tumour Suppressor Genes: -- APC and MCC. BRCA1 and BRCA2. DCC. DPC4. E2F1. E-cadherin/CDH1. MSH2. MSH3. MSH6/GTBP and MLHL. NF1 and NF2. P53, PTC. -- The Retinoblastoma Gene (RB1). TGFBR1 and TGFBR2. VHL; WT1. -- Cyclin-dependent Kinase Inhibitors: -- INK4A/MTS1/MTS2/CDK41/CDKN2. INK4B/MTS2. -- INK4C and INK4D. KIP1. KIP2. WAF1. -- DNA Tumour Viruses: -- Human Papillomaviruses. -- Epstein-Barr Virus. -- Subject Index | ||
| 500 | |a Includes bibliographical references and index | ||
| 500 | |a Sect. 1. The introductory chapters -- Genetic events in cancer delelopment -- Proliferation control pathways -- Tumour suppressor genes -- Cell cycle control -- Apoptosis -- DNA repair -- Angiogenesis and metastasis -- The multistep nature of cancer -- Gene therapy for cancer -- Sect. 2. Tables -- Oncogenes transduced by retroviruses -- Oncogenes activated by retroviral insertion -- Oncogenes at chromosomal translocations -- Tumour suppressor genes detected in human tumours -- Functions of oncoproteins -- Chromosome locations of human proto-oncogenes and tumour -- suppressor genes -- Sect. 3. The oncogenes -- Sect. 4. Tumour suppressor genes -- Sect. 5. Cyclin-dependent kinase inhibitors -- Sect. 6. DNA tumour viruses | ||
| 650 | 7 | |a MEDICAL / Oncology |2 bisacsh | |
| 650 | 7 | |a HEALTH & FITNESS / Diseases / Cancer |2 bisacsh | |
| 650 | 7 | |a Oncogenen |2 gtt | |
| 650 | 7 | |a Suppressorgenen |2 gtt | |
| 650 | 7 | |a Antioncogenes |2 fast | |
| 650 | 7 | |a Oncogenes |2 fast | |
| 650 | 4 | |a Genes, Tumor Suppressor | |
| 650 | 4 | |a Oncogenes | |
| 650 | 4 | |a Medizin | |
| 650 | 4 | |a Oncogenes | |
| 650 | 4 | |a Antioncogenes | |
| 650 | 0 | 7 | |a Onkogen |0 (DE-588)4131118-8 |2 gnd |9 rswk-swf |
| 650 | 0 | 7 | |a Tumorsuppressor-Gen |0 (DE-588)4326903-5 |2 gnd |9 rswk-swf |
| 655 | 7 | |8 1\p |0 (DE-588)4148875-1 |a Datensammlung |2 gnd-content | |
| 689 | 0 | 0 | |a Onkogen |0 (DE-588)4131118-8 |D s |
| 689 | 0 | |8 2\p |5 DE-604 | |
| 689 | 1 | 0 | |a Tumorsuppressor-Gen |0 (DE-588)4326903-5 |D s |
| 689 | 1 | |8 3\p |5 DE-604 | |
| 856 | 4 | 0 | |u http://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&db=nlabk&AN=230851 |x Aggregator |3 Volltext |
| 912 | |a ZDB-4-EBA | ||
| 999 | |a oai:aleph.bib-bvb.de:BVB01-028469309 | ||
| 883 | 1 | |8 1\p |a cgwrk |d 20201028 |q DE-101 |u https://d-nb.info/provenance/plan#cgwrk | |
| 883 | 1 | |8 2\p |a cgwrk |d 20201028 |q DE-101 |u https://d-nb.info/provenance/plan#cgwrk | |
| 883 | 1 | |8 3\p |a cgwrk |d 20201028 |q DE-101 |u https://d-nb.info/provenance/plan#cgwrk | |
| 966 | e | |u http://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&db=nlabk&AN=230851 |l FAW01 |p ZDB-4-EBA |q FAW_PDA_EBA |x Aggregator |3 Volltext | |
| 966 | e | |u http://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&db=nlabk&AN=230851 |l FAW02 |p ZDB-4-EBA |q FAW_PDA_EBA |x Aggregator |3 Volltext | |
Datensatz im Suchindex
| _version_ | 1804175410925142016 |
|---|---|
| any_adam_object | |
| author | Hesketh, Robin |
| author_facet | Hesketh, Robin |
| author_role | aut |
| author_sort | Hesketh, Robin |
| author_variant | r h rh |
| building | Verbundindex |
| bvnumber | BV043044772 |
| collection | ZDB-4-EBA |
| ctrlnum | (OCoLC)162572729 (DE-599)BVBBV043044772 |
| dewey-full | 616.99/4071 |
| dewey-hundreds | 600 - Technology (Applied sciences) |
| dewey-ones | 616 - Diseases |
| dewey-raw | 616.99/4071 |
| dewey-search | 616.99/4071 |
| dewey-sort | 3616.99 44071 |
| dewey-tens | 610 - Medicine and health |
| discipline | Medizin |
| edition | 2nd ed |
| format | Electronic eBook |
| fullrecord | <?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>06750nmm a2200697zc 4500</leader><controlfield tag="001">BV043044772</controlfield><controlfield tag="003">DE-604</controlfield><controlfield tag="005">00000000000000.0</controlfield><controlfield tag="007">cr|uuu---uuuuu</controlfield><controlfield tag="008">151123s1997 |||| o||u| ||||||eng d</controlfield><datafield tag="020" ind1=" " ind2=" "><subfield code="a">0080538002</subfield><subfield code="c">electronic bk.</subfield><subfield code="9">0-08-053800-2</subfield></datafield><datafield tag="020" ind1=" " ind2=" "><subfield code="a">0123445485</subfield><subfield code="9">0-12-344548-5</subfield></datafield><datafield tag="020" ind1=" " ind2=" "><subfield code="a">9780080538006</subfield><subfield code="c">electronic bk.</subfield><subfield code="9">978-0-08-053800-6</subfield></datafield><datafield tag="020" ind1=" " ind2=" "><subfield code="a">9780123445483</subfield><subfield code="9">978-0-12-344548-3</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(OCoLC)162572729</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-599)BVBBV043044772</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-604</subfield><subfield code="b">ger</subfield><subfield code="e">aacr</subfield></datafield><datafield tag="041" ind1="0" ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="049" ind1=" " ind2=" "><subfield code="a">DE-1046</subfield><subfield code="a">DE-1047</subfield></datafield><datafield tag="082" ind1="0" ind2=" "><subfield code="a">616.99/4071</subfield><subfield code="2">22</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Hesketh, Robin</subfield><subfield code="e">Verfasser</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">The oncogene and tumour suppressor gene factsbook</subfield><subfield code="c">Robin Hesketh</subfield></datafield><datafield tag="250" ind1=" " ind2=" "><subfield code="a">2nd ed</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="a">San Diego, Calif.</subfield><subfield code="b">Academic Press</subfield><subfield code="c">c1997</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">1 Online-Ressource (xiv, 549 p.)</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="490" ind1="0" ind2=" "><subfield code="a">Factsbook series</subfield></datafield><datafield tag="500" ind1=" " ind2=" "><subfield code="a">The Second Edition of The Oncogene and Tumour Suppressor Gene FactsBook has been completely revised, updated, and expanded by 60%. The book contains more than 80 entries on oncogenes including JUN, MYC, and RAS, as well as DNA tumour viruses, tumour suppressor genes, including p53, retinoblastoma, BRCA1, BRCA2, VHL, F2FL, and essential material on angiogenesis and metastasis, apoptosis, cell cycle control, and gene therapy. Key Features * Includes much new data on this fast-moving field, including newly discovered oncogenes * Summarizes the clinical association and molecular properties of all known oncogenes and tumor suppression genes * Contains more than 2000 terms for reference and further research * Revised to included signaling pathways, apoptosis, and metastasis</subfield></datafield><datafield tag="500" ind1=" " ind2=" "><subfield code="a">The Introductory Chapters: -- Introduction: Identification of Oncogenes. -- Oncogene Activation in Humans. -- Proliferation Control Pathways: Oncoprotein Function. -- Growth Factor-Related Proteins. -- SRC. RAS and RAF. -- Nuclear Oncoproteins. -- ETS. FOS and JUN. MYB. MYC. REL. ERBA. -- Tumour Suppressor Genes: RB1. P53. -- Other Major Tumour Suppressor Genes. -- APC. BRCA1. NF1. VHL. WT1. -- Cell Cycle Control: Cyclin-Dependent Kinase Inhibitors (CDKIs). -- Apoptosis: Tumour Suppressor Genes and Apoptosis. -- DNA Repair. -- Angiogenesis and Metastasis: Angiogenesis. -- Angiogenic Promoters. -- Angiogenic Inhibitors. -- Metastasis: Correlations with Gene Expression. -- Cadherins. -- The Immunoglobulin Superfamily (IgSF), Neural Cell-Adhesion Molecule (NCAM). -- Integrins. -- CD44. -- Matrix Metalloproteinases (MMPS). -- Tissue Inhibitors of Metalloproteinases (TIMPs). -- Cysteine and Aspartic Proteinases and Heparanase. -- NME1 and NME2. -- </subfield></datafield><datafield tag="500" ind1=" " ind2=" "><subfield code="a"> - The Multi-step Nature of Cancer: Cervical Carcinoma. -- Colorectal Carcinoma. -- Breast Carcinoma. -- Prostate Carcinoma. -- Renal Cell Carcinoma. -- Lung Carcinoma. -- Lymphomas. -- Chronic Myeloid Leukemia. -- Gene Therapy for Cancer: Nucleotide Sequence-Targeted Strategies. -- Tumour Suppressor Gene Therapy. -- Cytokine Gene Therapy and Tumour Vaccination. -- Virally Directed Enzyme Prodrug Therapy (VDEPT). -- Antibody-directed Therapy. -- Tables: -- Oncogenes Transduced by Retroviruses. -- Oncogenes Activated by Retroviral Insertion. -- Oncogenes at Chromosomal Translocations. -- Tumour Suppressor Genes Detected in Human Tumours. -- Functions of Oncoproteins. -- Chromosome Locations of Human Proto-Oncogenes and Tumour Suppressor Genes. -- The Oncogenes: -- </subfield></datafield><datafield tag="500" ind1=" " ind2=" "><subfield code="a"> - ABL. AKT1 and AKT2. BCL2. BCL3. BCR. CBL. CDK4. CRK. CSFIR/FMS. D Cyclins. DBL. EGFR/ErbB. ELK1. EPH. ERG. ETS1 and ETS2. FGR. FLII. FOS. FOSB. FPS/FES. FRA1 and FRA2. FYN. HCK. HER2/ErbB-2/Neu. HER3/ErbB-3. HER4/ErbB-4. HSTF1/HST2. INT2. JUN. JUNB. JUND. KIT. LCK. LYN. MAS. MAX. MET. Mil. MOS. MYB. MYC. PDGF/Sis. PIM1. RAF. RAS. REL. RET. ROS1. SEA. SKI. SRC. TAL1. THRA/ErbA-1 and THRA2/ErbA-2. TIAM1. TRK. VAV. WNT1. WNT2 and WNT3. YES1. -- Tumour Suppressor Genes: -- APC and MCC. BRCA1 and BRCA2. DCC. DPC4. E2F1. E-cadherin/CDH1. MSH2. MSH3. MSH6/GTBP and MLHL. NF1 and NF2. P53, PTC. -- The Retinoblastoma Gene (RB1). TGFBR1 and TGFBR2. VHL; WT1. -- Cyclin-dependent Kinase Inhibitors: -- INK4A/MTS1/MTS2/CDK41/CDKN2. INK4B/MTS2. -- INK4C and INK4D. KIP1. KIP2. WAF1. -- DNA Tumour Viruses: -- Human Papillomaviruses. -- Epstein-Barr Virus. -- Subject Index</subfield></datafield><datafield tag="500" ind1=" " ind2=" "><subfield code="a">Includes bibliographical references and index</subfield></datafield><datafield tag="500" ind1=" " ind2=" "><subfield code="a">Sect. 1. The introductory chapters -- Genetic events in cancer delelopment -- Proliferation control pathways -- Tumour suppressor genes -- Cell cycle control -- Apoptosis -- DNA repair -- Angiogenesis and metastasis -- The multistep nature of cancer -- Gene therapy for cancer -- Sect. 2. Tables -- Oncogenes transduced by retroviruses -- Oncogenes activated by retroviral insertion -- Oncogenes at chromosomal translocations -- Tumour suppressor genes detected in human tumours -- Functions of oncoproteins -- Chromosome locations of human proto-oncogenes and tumour -- suppressor genes -- Sect. 3. The oncogenes -- Sect. 4. Tumour suppressor genes -- Sect. 5. Cyclin-dependent kinase inhibitors -- Sect. 6. DNA tumour viruses</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">MEDICAL / Oncology</subfield><subfield code="2">bisacsh</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">HEALTH & FITNESS / Diseases / Cancer</subfield><subfield code="2">bisacsh</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">Oncogenen</subfield><subfield code="2">gtt</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">Suppressorgenen</subfield><subfield code="2">gtt</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">Antioncogenes</subfield><subfield code="2">fast</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">Oncogenes</subfield><subfield code="2">fast</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Genes, Tumor Suppressor</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Oncogenes</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Medizin</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Oncogenes</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Antioncogenes</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Onkogen</subfield><subfield code="0">(DE-588)4131118-8</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Tumorsuppressor-Gen</subfield><subfield code="0">(DE-588)4326903-5</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="655" ind1=" " ind2="7"><subfield code="8">1\p</subfield><subfield code="0">(DE-588)4148875-1</subfield><subfield code="a">Datensammlung</subfield><subfield code="2">gnd-content</subfield></datafield><datafield tag="689" ind1="0" ind2="0"><subfield code="a">Onkogen</subfield><subfield code="0">(DE-588)4131118-8</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="0" ind2=" "><subfield code="8">2\p</subfield><subfield code="5">DE-604</subfield></datafield><datafield tag="689" ind1="1" ind2="0"><subfield code="a">Tumorsuppressor-Gen</subfield><subfield code="0">(DE-588)4326903-5</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="1" ind2=" "><subfield code="8">3\p</subfield><subfield code="5">DE-604</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">http://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&db=nlabk&AN=230851</subfield><subfield code="x">Aggregator</subfield><subfield code="3">Volltext</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">ZDB-4-EBA</subfield></datafield><datafield tag="999" ind1=" " ind2=" "><subfield code="a">oai:aleph.bib-bvb.de:BVB01-028469309</subfield></datafield><datafield tag="883" ind1="1" ind2=" "><subfield code="8">1\p</subfield><subfield code="a">cgwrk</subfield><subfield code="d">20201028</subfield><subfield code="q">DE-101</subfield><subfield code="u">https://d-nb.info/provenance/plan#cgwrk</subfield></datafield><datafield tag="883" ind1="1" ind2=" "><subfield code="8">2\p</subfield><subfield code="a">cgwrk</subfield><subfield code="d">20201028</subfield><subfield code="q">DE-101</subfield><subfield code="u">https://d-nb.info/provenance/plan#cgwrk</subfield></datafield><datafield tag="883" ind1="1" ind2=" "><subfield code="8">3\p</subfield><subfield code="a">cgwrk</subfield><subfield code="d">20201028</subfield><subfield code="q">DE-101</subfield><subfield code="u">https://d-nb.info/provenance/plan#cgwrk</subfield></datafield><datafield tag="966" ind1="e" ind2=" "><subfield code="u">http://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&db=nlabk&AN=230851</subfield><subfield code="l">FAW01</subfield><subfield code="p">ZDB-4-EBA</subfield><subfield code="q">FAW_PDA_EBA</subfield><subfield code="x">Aggregator</subfield><subfield code="3">Volltext</subfield></datafield><datafield tag="966" ind1="e" ind2=" "><subfield code="u">http://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&db=nlabk&AN=230851</subfield><subfield code="l">FAW02</subfield><subfield code="p">ZDB-4-EBA</subfield><subfield code="q">FAW_PDA_EBA</subfield><subfield code="x">Aggregator</subfield><subfield code="3">Volltext</subfield></datafield></record></collection> |
| genre | 1\p (DE-588)4148875-1 Datensammlung gnd-content |
| genre_facet | Datensammlung |
| id | DE-604.BV043044772 |
| illustrated | Not Illustrated |
| indexdate | 2024-07-10T07:15:51Z |
| institution | BVB |
| isbn | 0080538002 0123445485 9780080538006 9780123445483 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-028469309 |
| oclc_num | 162572729 |
| open_access_boolean | |
| owner | DE-1046 DE-1047 |
| owner_facet | DE-1046 DE-1047 |
| physical | 1 Online-Ressource (xiv, 549 p.) |
| psigel | ZDB-4-EBA ZDB-4-EBA FAW_PDA_EBA |
| publishDate | 1997 |
| publishDateSearch | 1997 |
| publishDateSort | 1997 |
| publisher | Academic Press |
| record_format | marc |
| series2 | Factsbook series |
| spelling | Hesketh, Robin Verfasser aut The oncogene and tumour suppressor gene factsbook Robin Hesketh 2nd ed San Diego, Calif. Academic Press c1997 1 Online-Ressource (xiv, 549 p.) txt rdacontent c rdamedia cr rdacarrier Factsbook series The Second Edition of The Oncogene and Tumour Suppressor Gene FactsBook has been completely revised, updated, and expanded by 60%. The book contains more than 80 entries on oncogenes including JUN, MYC, and RAS, as well as DNA tumour viruses, tumour suppressor genes, including p53, retinoblastoma, BRCA1, BRCA2, VHL, F2FL, and essential material on angiogenesis and metastasis, apoptosis, cell cycle control, and gene therapy. Key Features * Includes much new data on this fast-moving field, including newly discovered oncogenes * Summarizes the clinical association and molecular properties of all known oncogenes and tumor suppression genes * Contains more than 2000 terms for reference and further research * Revised to included signaling pathways, apoptosis, and metastasis The Introductory Chapters: -- Introduction: Identification of Oncogenes. -- Oncogene Activation in Humans. -- Proliferation Control Pathways: Oncoprotein Function. -- Growth Factor-Related Proteins. -- SRC. RAS and RAF. -- Nuclear Oncoproteins. -- ETS. FOS and JUN. MYB. MYC. REL. ERBA. -- Tumour Suppressor Genes: RB1. P53. -- Other Major Tumour Suppressor Genes. -- APC. BRCA1. NF1. VHL. WT1. -- Cell Cycle Control: Cyclin-Dependent Kinase Inhibitors (CDKIs). -- Apoptosis: Tumour Suppressor Genes and Apoptosis. -- DNA Repair. -- Angiogenesis and Metastasis: Angiogenesis. -- Angiogenic Promoters. -- Angiogenic Inhibitors. -- Metastasis: Correlations with Gene Expression. -- Cadherins. -- The Immunoglobulin Superfamily (IgSF), Neural Cell-Adhesion Molecule (NCAM). -- Integrins. -- CD44. -- Matrix Metalloproteinases (MMPS). -- Tissue Inhibitors of Metalloproteinases (TIMPs). -- Cysteine and Aspartic Proteinases and Heparanase. -- NME1 and NME2. -- - The Multi-step Nature of Cancer: Cervical Carcinoma. -- Colorectal Carcinoma. -- Breast Carcinoma. -- Prostate Carcinoma. -- Renal Cell Carcinoma. -- Lung Carcinoma. -- Lymphomas. -- Chronic Myeloid Leukemia. -- Gene Therapy for Cancer: Nucleotide Sequence-Targeted Strategies. -- Tumour Suppressor Gene Therapy. -- Cytokine Gene Therapy and Tumour Vaccination. -- Virally Directed Enzyme Prodrug Therapy (VDEPT). -- Antibody-directed Therapy. -- Tables: -- Oncogenes Transduced by Retroviruses. -- Oncogenes Activated by Retroviral Insertion. -- Oncogenes at Chromosomal Translocations. -- Tumour Suppressor Genes Detected in Human Tumours. -- Functions of Oncoproteins. -- Chromosome Locations of Human Proto-Oncogenes and Tumour Suppressor Genes. -- The Oncogenes: -- - ABL. AKT1 and AKT2. BCL2. BCL3. BCR. CBL. CDK4. CRK. CSFIR/FMS. D Cyclins. DBL. EGFR/ErbB. ELK1. EPH. ERG. ETS1 and ETS2. FGR. FLII. FOS. FOSB. FPS/FES. FRA1 and FRA2. FYN. HCK. HER2/ErbB-2/Neu. HER3/ErbB-3. HER4/ErbB-4. HSTF1/HST2. INT2. JUN. JUNB. JUND. KIT. LCK. LYN. MAS. MAX. MET. Mil. MOS. MYB. MYC. PDGF/Sis. PIM1. RAF. RAS. REL. RET. ROS1. SEA. SKI. SRC. TAL1. THRA/ErbA-1 and THRA2/ErbA-2. TIAM1. TRK. VAV. WNT1. WNT2 and WNT3. YES1. -- Tumour Suppressor Genes: -- APC and MCC. BRCA1 and BRCA2. DCC. DPC4. E2F1. E-cadherin/CDH1. MSH2. MSH3. MSH6/GTBP and MLHL. NF1 and NF2. P53, PTC. -- The Retinoblastoma Gene (RB1). TGFBR1 and TGFBR2. VHL; WT1. -- Cyclin-dependent Kinase Inhibitors: -- INK4A/MTS1/MTS2/CDK41/CDKN2. INK4B/MTS2. -- INK4C and INK4D. KIP1. KIP2. WAF1. -- DNA Tumour Viruses: -- Human Papillomaviruses. -- Epstein-Barr Virus. -- Subject Index Includes bibliographical references and index Sect. 1. The introductory chapters -- Genetic events in cancer delelopment -- Proliferation control pathways -- Tumour suppressor genes -- Cell cycle control -- Apoptosis -- DNA repair -- Angiogenesis and metastasis -- The multistep nature of cancer -- Gene therapy for cancer -- Sect. 2. Tables -- Oncogenes transduced by retroviruses -- Oncogenes activated by retroviral insertion -- Oncogenes at chromosomal translocations -- Tumour suppressor genes detected in human tumours -- Functions of oncoproteins -- Chromosome locations of human proto-oncogenes and tumour -- suppressor genes -- Sect. 3. The oncogenes -- Sect. 4. Tumour suppressor genes -- Sect. 5. Cyclin-dependent kinase inhibitors -- Sect. 6. DNA tumour viruses MEDICAL / Oncology bisacsh HEALTH & FITNESS / Diseases / Cancer bisacsh Oncogenen gtt Suppressorgenen gtt Antioncogenes fast Oncogenes fast Genes, Tumor Suppressor Oncogenes Medizin Antioncogenes Onkogen (DE-588)4131118-8 gnd rswk-swf Tumorsuppressor-Gen (DE-588)4326903-5 gnd rswk-swf 1\p (DE-588)4148875-1 Datensammlung gnd-content Onkogen (DE-588)4131118-8 s 2\p DE-604 Tumorsuppressor-Gen (DE-588)4326903-5 s 3\p DE-604 http://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&db=nlabk&AN=230851 Aggregator Volltext 1\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk 2\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk 3\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk |
| spellingShingle | Hesketh, Robin The oncogene and tumour suppressor gene factsbook MEDICAL / Oncology bisacsh HEALTH & FITNESS / Diseases / Cancer bisacsh Oncogenen gtt Suppressorgenen gtt Antioncogenes fast Oncogenes fast Genes, Tumor Suppressor Oncogenes Medizin Antioncogenes Onkogen (DE-588)4131118-8 gnd Tumorsuppressor-Gen (DE-588)4326903-5 gnd |
| subject_GND | (DE-588)4131118-8 (DE-588)4326903-5 (DE-588)4148875-1 |
| title | The oncogene and tumour suppressor gene factsbook |
| title_auth | The oncogene and tumour suppressor gene factsbook |
| title_exact_search | The oncogene and tumour suppressor gene factsbook |
| title_full | The oncogene and tumour suppressor gene factsbook Robin Hesketh |
| title_fullStr | The oncogene and tumour suppressor gene factsbook Robin Hesketh |
| title_full_unstemmed | The oncogene and tumour suppressor gene factsbook Robin Hesketh |
| title_short | The oncogene and tumour suppressor gene factsbook |
| title_sort | the oncogene and tumour suppressor gene factsbook |
| topic | MEDICAL / Oncology bisacsh HEALTH & FITNESS / Diseases / Cancer bisacsh Oncogenen gtt Suppressorgenen gtt Antioncogenes fast Oncogenes fast Genes, Tumor Suppressor Oncogenes Medizin Antioncogenes Onkogen (DE-588)4131118-8 gnd Tumorsuppressor-Gen (DE-588)4326903-5 gnd |
| topic_facet | MEDICAL / Oncology HEALTH & FITNESS / Diseases / Cancer Oncogenen Suppressorgenen Antioncogenes Oncogenes Genes, Tumor Suppressor Medizin Onkogen Tumorsuppressor-Gen Datensammlung |
| url | http://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&db=nlabk&AN=230851 |
| work_keys_str_mv | AT heskethrobin theoncogeneandtumoursuppressorgenefactsbook |