Self-perpetuating structural states in biology, disease, and genetics:
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Format: | Elektronisch E-Book |
Sprache: | English |
Veröffentlicht: |
Washington, DC
National Academy of Sciences
[2002]
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Schlagworte: | |
Online-Zugang: | FAW01 FAW02 Volltext |
Beschreibung: | Title from title screen Description based on version viewed January 12, 2015 |
Beschreibung: | 1 online resource illustrations |
ISBN: | 0309084458 030957045X 9780309084451 9780309570459 |
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505 | 8 | |a Over the past half-century, the central dogma, in which DNA makes RNA makes protein, has dominated thinking in biology, with continuing refinements in understanding of DNA inheritance, gene expression, and macromolecular interactions. However, we have also witnessed the elucidation of epigenetic phenomena that violate conventional notions of inheritance. Protein-only inheritance involves the transmission of phenotypes by self-perpetuating changes in protein conformation. Proteins that constitute chromatin can also transmit heritable information, for example, via posttranslational modifications of histones. Both the transmission of phenotypes via the formation of protein conformations and the inheritance of chromatin states involve self-perpetuating assemblies of proteins, and there is evidence for some common structural features and conceptual frameworks between them. To foster interactions between researchers in these two fields, the National Academy of Sciences convened an Arthur M.Sackler Colloquium entitled "Self-Perpetuating Structural States in Biology, Disease, and Genetics" in Washington, DC, on March 22-24, 2002. Participants described new phenomenology and provided insights into fundamental mechanisms of protein and chromatin inheritance. Perhaps most surprising to attendees was emerging evidence that these unconventional modes of inheritance may be common | |
650 | 4 | |a Chromatin / genetics / Congresses | |
650 | 4 | |a Epigenesis, Genetic / Congresses | |
650 | 4 | |a Histones / genetics / Congresses | |
650 | 4 | |a Protein Conformation / Congresses | |
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650 | 4 | |a Prions |v Congresses | |
650 | 4 | |a Chromatin |v Congresses | |
650 | 4 | |a Proteins |x Conformation |v Congresses | |
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776 | 0 | 8 | |i Erscheint auch als |n Druck-Ausgabe |a Arthur M. Sackler Colloquia of the National Academy of Sciences (2002 : Washington, D |t C.). Self-perpetuating structural states in biology, disease, and genetics |
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Datensatz im Suchindex
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---|---|
any_adam_object | |
author2 | Lindquist, Susan Henikoff, Steve |
author2_role | edt edt |
author2_variant | s l sl s h sh |
author_corporate | Arthur M. Sackler Colloquia of the National Academy of Sciences <2002, Washington, D.C.> |
author_corporate_role | aut |
author_facet | Lindquist, Susan Henikoff, Steve Arthur M. Sackler Colloquia of the National Academy of Sciences <2002, Washington, D.C.> |
author_sort | Arthur M. Sackler Colloquia of the National Academy of Sciences <2002, Washington, D.C.> |
building | Verbundindex |
bvnumber | BV043039006 |
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contents | Over the past half-century, the central dogma, in which DNA makes RNA makes protein, has dominated thinking in biology, with continuing refinements in understanding of DNA inheritance, gene expression, and macromolecular interactions. However, we have also witnessed the elucidation of epigenetic phenomena that violate conventional notions of inheritance. Protein-only inheritance involves the transmission of phenotypes by self-perpetuating changes in protein conformation. Proteins that constitute chromatin can also transmit heritable information, for example, via posttranslational modifications of histones. Both the transmission of phenotypes via the formation of protein conformations and the inheritance of chromatin states involve self-perpetuating assemblies of proteins, and there is evidence for some common structural features and conceptual frameworks between them. To foster interactions between researchers in these two fields, the National Academy of Sciences convened an Arthur M.Sackler Colloquium entitled "Self-Perpetuating Structural States in Biology, Disease, and Genetics" in Washington, DC, on March 22-24, 2002. Participants described new phenomenology and provided insights into fundamental mechanisms of protein and chromatin inheritance. Perhaps most surprising to attendees was emerging evidence that these unconventional modes of inheritance may be common |
ctrlnum | (OCoLC)70723111 (DE-599)BVBBV043039006 |
dewey-full | 572.8/7 500S |
dewey-hundreds | 500 - Natural sciences and mathematics |
dewey-ones | 572 - Biochemistry 500 - Natural sciences and mathematics |
dewey-raw | 572.8/7 500 s |
dewey-search | 572.8/7 500 s |
dewey-sort | 3572.8 17 |
dewey-tens | 570 - Biology 500 - Natural sciences and mathematics |
discipline | Allgemeine Naturwissenschaft Biologie |
format | Electronic eBook |
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spelling | Arthur M. Sackler Colloquia of the National Academy of Sciences <2002, Washington, D.C.> Verfasser aut Self-perpetuating structural states in biology, disease, and genetics edited by Susan Lindquist, Steve Henikoff Washington, DC National Academy of Sciences [2002] 1 online resource illustrations txt rdacontent c rdamedia cr rdacarrier Title from title screen Description based on version viewed January 12, 2015 Over the past half-century, the central dogma, in which DNA makes RNA makes protein, has dominated thinking in biology, with continuing refinements in understanding of DNA inheritance, gene expression, and macromolecular interactions. However, we have also witnessed the elucidation of epigenetic phenomena that violate conventional notions of inheritance. Protein-only inheritance involves the transmission of phenotypes by self-perpetuating changes in protein conformation. Proteins that constitute chromatin can also transmit heritable information, for example, via posttranslational modifications of histones. Both the transmission of phenotypes via the formation of protein conformations and the inheritance of chromatin states involve self-perpetuating assemblies of proteins, and there is evidence for some common structural features and conceptual frameworks between them. To foster interactions between researchers in these two fields, the National Academy of Sciences convened an Arthur M.Sackler Colloquium entitled "Self-Perpetuating Structural States in Biology, Disease, and Genetics" in Washington, DC, on March 22-24, 2002. Participants described new phenomenology and provided insights into fundamental mechanisms of protein and chromatin inheritance. Perhaps most surprising to attendees was emerging evidence that these unconventional modes of inheritance may be common Chromatin / genetics / Congresses Epigenesis, Genetic / Congresses Histones / genetics / Congresses Protein Conformation / Congresses Biology Proteins / Conformation SCIENCE / Essays bisacsh SCIENCE / Nanoscience bisacsh SCIENCE / Reference bisacsh Biology fast Cellular control mechanisms fast Chromatin fast DNA. fast Prions fast Proteins / Conformation fast Cellular control mechanisms Congresses Biology Congresses DNA Congresses Prions Congresses Chromatin Congresses Proteins Conformation Congresses (DE-588)1071861417 Konferenzschrift gnd-content Lindquist, Susan edt Henikoff, Steve edt National Academy of Sciences (U.S.) Sonstige oth Erscheint auch als Druck-Ausgabe Arthur M. Sackler Colloquia of the National Academy of Sciences (2002 : Washington, D C.). Self-perpetuating structural states in biology, disease, and genetics http://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&db=nlabk&AN=123502 Aggregator Volltext |
spellingShingle | Self-perpetuating structural states in biology, disease, and genetics Over the past half-century, the central dogma, in which DNA makes RNA makes protein, has dominated thinking in biology, with continuing refinements in understanding of DNA inheritance, gene expression, and macromolecular interactions. However, we have also witnessed the elucidation of epigenetic phenomena that violate conventional notions of inheritance. Protein-only inheritance involves the transmission of phenotypes by self-perpetuating changes in protein conformation. Proteins that constitute chromatin can also transmit heritable information, for example, via posttranslational modifications of histones. Both the transmission of phenotypes via the formation of protein conformations and the inheritance of chromatin states involve self-perpetuating assemblies of proteins, and there is evidence for some common structural features and conceptual frameworks between them. To foster interactions between researchers in these two fields, the National Academy of Sciences convened an Arthur M.Sackler Colloquium entitled "Self-Perpetuating Structural States in Biology, Disease, and Genetics" in Washington, DC, on March 22-24, 2002. Participants described new phenomenology and provided insights into fundamental mechanisms of protein and chromatin inheritance. Perhaps most surprising to attendees was emerging evidence that these unconventional modes of inheritance may be common Chromatin / genetics / Congresses Epigenesis, Genetic / Congresses Histones / genetics / Congresses Protein Conformation / Congresses Biology Proteins / Conformation SCIENCE / Essays bisacsh SCIENCE / Nanoscience bisacsh SCIENCE / Reference bisacsh Biology fast Cellular control mechanisms fast Chromatin fast DNA. fast Prions fast Proteins / Conformation fast Cellular control mechanisms Congresses Biology Congresses DNA Congresses Prions Congresses Chromatin Congresses Proteins Conformation Congresses |
subject_GND | (DE-588)1071861417 |
title | Self-perpetuating structural states in biology, disease, and genetics |
title_auth | Self-perpetuating structural states in biology, disease, and genetics |
title_exact_search | Self-perpetuating structural states in biology, disease, and genetics |
title_full | Self-perpetuating structural states in biology, disease, and genetics edited by Susan Lindquist, Steve Henikoff |
title_fullStr | Self-perpetuating structural states in biology, disease, and genetics edited by Susan Lindquist, Steve Henikoff |
title_full_unstemmed | Self-perpetuating structural states in biology, disease, and genetics edited by Susan Lindquist, Steve Henikoff |
title_short | Self-perpetuating structural states in biology, disease, and genetics |
title_sort | self perpetuating structural states in biology disease and genetics |
topic | Chromatin / genetics / Congresses Epigenesis, Genetic / Congresses Histones / genetics / Congresses Protein Conformation / Congresses Biology Proteins / Conformation SCIENCE / Essays bisacsh SCIENCE / Nanoscience bisacsh SCIENCE / Reference bisacsh Biology fast Cellular control mechanisms fast Chromatin fast DNA. fast Prions fast Proteins / Conformation fast Cellular control mechanisms Congresses Biology Congresses DNA Congresses Prions Congresses Chromatin Congresses Proteins Conformation Congresses |
topic_facet | Chromatin / genetics / Congresses Epigenesis, Genetic / Congresses Histones / genetics / Congresses Protein Conformation / Congresses Biology Proteins / Conformation SCIENCE / Essays SCIENCE / Nanoscience SCIENCE / Reference Cellular control mechanisms Chromatin DNA. Prions Cellular control mechanisms Congresses Biology Congresses DNA Congresses Prions Congresses Chromatin Congresses Proteins Conformation Congresses Konferenzschrift |
url | http://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&db=nlabk&AN=123502 |
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