Veterans and Agent Orange: update 2012
Gespeichert in:
| Körperschaft: | |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Washington (DC)
National Academies Press (US)
2014
|
| Schlagworte: | |
| Online-Zugang: | FAW01 FAW02 Volltext |
| Beschreibung: | Title from PDF title page Description based on version viewed June 2, 2014 |
| Beschreibung: | 1 online resource (1 PDF file (xix, 986 pages)) |
| ISBN: | 030928886X 0309288878 9780309288866 9780309288873 |
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| 505 | 8 | |a From 1962 to 1971, the US military sprayed herbicides over Vietnam to strip the thick jungle canopy that could conceal opposition forces, to destroy crops that those forces might depend on, and to clear tall grasses and bushes from the perimeters of US base camps and outlying fire-support bases. Mixtures of 2,4-dichlorophenoxyacetic acid (2,4-D), 2,4,5-trichlorophenoxyacetic acid (2,4,5-T), picloram, and cacodylic acid made up the bulk of the herbicides sprayed. The main chemical mixture sprayed was Agent Orange, a 50:50 mixture of 2,4-D and 2,4,5-T. At the time of the spraying, 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), the most toxic form of dioxin, was an unintended contaminant generated during the production of 2,4,5-T and so was present in Agent Orange and some other formulations sprayed in Vietnam. | |
| 505 | 8 | |a Because of complaints from returning Vietnam veterans about their own health and that of their children combined with emerging toxicologic evidence of adverse effects of phenoxy herbicides and TCDD, the National Academy of Sciences (NAS) was asked to perform a comprehensive evaluation of scientific and medical information regarding the health effects of exposure to Agent Orange, other herbicides used in Vietnam, and the various components of those herbicides, including TCDD. Updated evaluations are conducted every two years to review newly available literature and draw conclusions from the overall evidence.Veterans and Agent Orange: Update 2012 reviews peer-reviewed scientific reports concerning associations between health outcomes and exposure to TCDD and other chemicals in the herbicides used in Vietnam that were published in October 2010--September 2012 and integrates this information with the previously established evidence database. | |
| 505 | 8 | |a This report considers whether a statistical association with herbicide exposure exists, taking into account the strength of the scientific evidence and the appropriateness of the statistical and epidemiological methods used to detect the association; the increased risk of disease among those exposed to herbicides during service in the Republic of Vietnam during the Vietnam era; and whether there exists a plausible biological mechanism or other evidence of a causal relationship between herbicide exposure and the disease | |
| 505 | 8 | |a Summary -- 1. Introduction -- 2. Evaluating the evidence -- 3. Exposure to the herbicides used in Vietnam -- 4. Information related to biologic plausibility -- 5. Epidemiologic studies: compendium of new publications -- 6. Epidemiologic studies: background on multiply referenced populations -- 7. Immune-system disorders -- 8. Cancer -- 9. Fertility and gestational outcomes -- 10. Effects on future generations -- 11. Neurologic disorders -- 12. Cardiovascular and metabolic outcomes -- 13. Other chronic health outcomes -- 14. Conclusions and recommendations -- Appendix A: Issues raised by the public and agendas of public meetings held by the Commitee to Review the Health Effects in Vietnam Veterans of Exposure to Herbicides (Ninth Biennial Update) and other written submissions to the Committee -- Appendix B: Short-term adverse health responses -- Appendix C: Clarification of cancer groupings used in reporting results, with correspondence to National Institute for Occupational Safety and Health and health cause-of-death codes and international classification of diseases codes for cancers -- Appendix D: Biographies of Commitee to Review the Health Effects in Vietnam Veterans of Exposure to Herbicides (Ninth Biennial Update) and staff | |
| 610 | 1 | 7 | |a Vietnam War (1961-1975) |2 fast |
| 648 | 7 | |a 1961 - 1975 |2 fast | |
| 650 | 4 | |a Tetrachlorodibenzodioxin / adverse effects / United States | |
| 650 | 4 | |a Defoliants, Chemical / adverse effects / United States | |
| 650 | 4 | |a Occupational Exposure / United States | |
| 650 | 4 | |a Veterans Health / United States | |
| 650 | 4 | |a Vietnam Conflict / United States | |
| 650 | 7 | |a MEDICAL / Toxicology |2 bisacsh | |
| 650 | 7 | |a Agent Orange / Health aspects |2 fast | |
| 650 | 7 | |a Agent Orange / Toxicology |2 fast | |
| 650 | 7 | |a Veterans / Health risk assessment |2 fast | |
| 650 | 4 | |a Medizin | |
| 650 | 4 | |a Vietnamkrieg | |
| 650 | 4 | |a Agent Orange |x Toxicology | |
| 650 | 4 | |a Vietnam War, 1961-1975 |x Veterans |x Health aspects | |
| 650 | 4 | |a Vietnam War, 1961-1975 |x Veterans |x Diseases | |
| 650 | 4 | |a Herbicides |x Toxicology | |
| 650 | 4 | |a Epidemiology | |
| 651 | 4 | |a USA | |
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| 776 | 0 | 8 | |i Erscheint auch als |n Druck-Ausgabe |a Institute of Medicine (U.S.) Committee to Review the Health Effects in Vietnam Veterans of Exposure to Herbicides. Veterans and agent orange |
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| author_corporate | Institute of Medicine (U.S.) Committee to Review the Health Effects in Vietnam Veterans of Exposure to Herbicides |
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| author_facet | Institute of Medicine (U.S.) Committee to Review the Health Effects in Vietnam Veterans of Exposure to Herbicides |
| author_sort | Institute of Medicine (U.S.) Committee to Review the Health Effects in Vietnam Veterans of Exposure to Herbicides |
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| contents | From 1962 to 1971, the US military sprayed herbicides over Vietnam to strip the thick jungle canopy that could conceal opposition forces, to destroy crops that those forces might depend on, and to clear tall grasses and bushes from the perimeters of US base camps and outlying fire-support bases. Mixtures of 2,4-dichlorophenoxyacetic acid (2,4-D), 2,4,5-trichlorophenoxyacetic acid (2,4,5-T), picloram, and cacodylic acid made up the bulk of the herbicides sprayed. The main chemical mixture sprayed was Agent Orange, a 50:50 mixture of 2,4-D and 2,4,5-T. At the time of the spraying, 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), the most toxic form of dioxin, was an unintended contaminant generated during the production of 2,4,5-T and so was present in Agent Orange and some other formulations sprayed in Vietnam. Because of complaints from returning Vietnam veterans about their own health and that of their children combined with emerging toxicologic evidence of adverse effects of phenoxy herbicides and TCDD, the National Academy of Sciences (NAS) was asked to perform a comprehensive evaluation of scientific and medical information regarding the health effects of exposure to Agent Orange, other herbicides used in Vietnam, and the various components of those herbicides, including TCDD. Updated evaluations are conducted every two years to review newly available literature and draw conclusions from the overall evidence.Veterans and Agent Orange: Update 2012 reviews peer-reviewed scientific reports concerning associations between health outcomes and exposure to TCDD and other chemicals in the herbicides used in Vietnam that were published in October 2010--September 2012 and integrates this information with the previously established evidence database. This report considers whether a statistical association with herbicide exposure exists, taking into account the strength of the scientific evidence and the appropriateness of the statistical and epidemiological methods used to detect the association; the increased risk of disease among those exposed to herbicides during service in the Republic of Vietnam during the Vietnam era; and whether there exists a plausible biological mechanism or other evidence of a causal relationship between herbicide exposure and the disease Summary -- 1. Introduction -- 2. Evaluating the evidence -- 3. Exposure to the herbicides used in Vietnam -- 4. Information related to biologic plausibility -- 5. Epidemiologic studies: compendium of new publications -- 6. Epidemiologic studies: background on multiply referenced populations -- 7. Immune-system disorders -- 8. Cancer -- 9. Fertility and gestational outcomes -- 10. Effects on future generations -- 11. Neurologic disorders -- 12. Cardiovascular and metabolic outcomes -- 13. Other chronic health outcomes -- 14. Conclusions and recommendations -- Appendix A: Issues raised by the public and agendas of public meetings held by the Commitee to Review the Health Effects in Vietnam Veterans of Exposure to Herbicides (Ninth Biennial Update) and other written submissions to the Committee -- Appendix B: Short-term adverse health responses -- Appendix C: Clarification of cancer groupings used in reporting results, with correspondence to National Institute for Occupational Safety and Health and health cause-of-death codes and international classification of diseases codes for cancers -- Appendix D: Biographies of Commitee to Review the Health Effects in Vietnam Veterans of Exposure to Herbicides (Ninth Biennial Update) and staff |
| ctrlnum | (OCoLC)881019388 (DE-599)BVBBV043030731 |
| dewey-full | 615.9/5137 |
| dewey-hundreds | 600 - Technology (Applied sciences) |
| dewey-ones | 615 - Pharmacology and therapeutics |
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| discipline | Medizin |
| era | 1961 - 1975 fast |
| era_facet | 1961 - 1975 |
| format | Electronic eBook |
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| geographic | USA |
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| id | DE-604.BV043030731 |
| illustrated | Not Illustrated |
| indexdate | 2024-07-10T07:15:28Z |
| institution | BVB |
| isbn | 030928886X 0309288878 9780309288866 9780309288873 |
| language | English |
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| spelling | Institute of Medicine (U.S.) Committee to Review the Health Effects in Vietnam Veterans of Exposure to Herbicides Verfasser aut Veterans and Agent Orange update 2012 Committee to Review the Health Effects in Vietnam Veterans of Exposure to Herbicides (Ninth Biennial Update), Board on the Health of Select Populations, Institute of Medicine Washington (DC) National Academies Press (US) 2014 1 online resource (1 PDF file (xix, 986 pages)) txt rdacontent c rdamedia cr rdacarrier Title from PDF title page Description based on version viewed June 2, 2014 From 1962 to 1971, the US military sprayed herbicides over Vietnam to strip the thick jungle canopy that could conceal opposition forces, to destroy crops that those forces might depend on, and to clear tall grasses and bushes from the perimeters of US base camps and outlying fire-support bases. Mixtures of 2,4-dichlorophenoxyacetic acid (2,4-D), 2,4,5-trichlorophenoxyacetic acid (2,4,5-T), picloram, and cacodylic acid made up the bulk of the herbicides sprayed. The main chemical mixture sprayed was Agent Orange, a 50:50 mixture of 2,4-D and 2,4,5-T. At the time of the spraying, 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), the most toxic form of dioxin, was an unintended contaminant generated during the production of 2,4,5-T and so was present in Agent Orange and some other formulations sprayed in Vietnam. Because of complaints from returning Vietnam veterans about their own health and that of their children combined with emerging toxicologic evidence of adverse effects of phenoxy herbicides and TCDD, the National Academy of Sciences (NAS) was asked to perform a comprehensive evaluation of scientific and medical information regarding the health effects of exposure to Agent Orange, other herbicides used in Vietnam, and the various components of those herbicides, including TCDD. Updated evaluations are conducted every two years to review newly available literature and draw conclusions from the overall evidence.Veterans and Agent Orange: Update 2012 reviews peer-reviewed scientific reports concerning associations between health outcomes and exposure to TCDD and other chemicals in the herbicides used in Vietnam that were published in October 2010--September 2012 and integrates this information with the previously established evidence database. This report considers whether a statistical association with herbicide exposure exists, taking into account the strength of the scientific evidence and the appropriateness of the statistical and epidemiological methods used to detect the association; the increased risk of disease among those exposed to herbicides during service in the Republic of Vietnam during the Vietnam era; and whether there exists a plausible biological mechanism or other evidence of a causal relationship between herbicide exposure and the disease Summary -- 1. Introduction -- 2. Evaluating the evidence -- 3. Exposure to the herbicides used in Vietnam -- 4. Information related to biologic plausibility -- 5. Epidemiologic studies: compendium of new publications -- 6. Epidemiologic studies: background on multiply referenced populations -- 7. Immune-system disorders -- 8. Cancer -- 9. Fertility and gestational outcomes -- 10. Effects on future generations -- 11. Neurologic disorders -- 12. Cardiovascular and metabolic outcomes -- 13. Other chronic health outcomes -- 14. Conclusions and recommendations -- Appendix A: Issues raised by the public and agendas of public meetings held by the Commitee to Review the Health Effects in Vietnam Veterans of Exposure to Herbicides (Ninth Biennial Update) and other written submissions to the Committee -- Appendix B: Short-term adverse health responses -- Appendix C: Clarification of cancer groupings used in reporting results, with correspondence to National Institute for Occupational Safety and Health and health cause-of-death codes and international classification of diseases codes for cancers -- Appendix D: Biographies of Commitee to Review the Health Effects in Vietnam Veterans of Exposure to Herbicides (Ninth Biennial Update) and staff Vietnam War (1961-1975) fast 1961 - 1975 fast Tetrachlorodibenzodioxin / adverse effects / United States Defoliants, Chemical / adverse effects / United States Occupational Exposure / United States Veterans Health / United States Vietnam Conflict / United States MEDICAL / Toxicology bisacsh Agent Orange / Health aspects fast Agent Orange / Toxicology fast Veterans / Health risk assessment fast Medizin Vietnamkrieg Agent Orange Toxicology Vietnam War, 1961-1975 Veterans Health aspects Vietnam War, 1961-1975 Veterans Diseases Herbicides Toxicology Epidemiology USA Institute of Medicine (U.S.) Board on the Health of Select Populations Sonstige oth Erscheint auch als Druck-Ausgabe Institute of Medicine (U.S.) Committee to Review the Health Effects in Vietnam Veterans of Exposure to Herbicides. Veterans and agent orange http://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&db=nlabk&AN=867988 Aggregator Volltext |
| spellingShingle | Veterans and Agent Orange update 2012 From 1962 to 1971, the US military sprayed herbicides over Vietnam to strip the thick jungle canopy that could conceal opposition forces, to destroy crops that those forces might depend on, and to clear tall grasses and bushes from the perimeters of US base camps and outlying fire-support bases. Mixtures of 2,4-dichlorophenoxyacetic acid (2,4-D), 2,4,5-trichlorophenoxyacetic acid (2,4,5-T), picloram, and cacodylic acid made up the bulk of the herbicides sprayed. The main chemical mixture sprayed was Agent Orange, a 50:50 mixture of 2,4-D and 2,4,5-T. At the time of the spraying, 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), the most toxic form of dioxin, was an unintended contaminant generated during the production of 2,4,5-T and so was present in Agent Orange and some other formulations sprayed in Vietnam. Because of complaints from returning Vietnam veterans about their own health and that of their children combined with emerging toxicologic evidence of adverse effects of phenoxy herbicides and TCDD, the National Academy of Sciences (NAS) was asked to perform a comprehensive evaluation of scientific and medical information regarding the health effects of exposure to Agent Orange, other herbicides used in Vietnam, and the various components of those herbicides, including TCDD. Updated evaluations are conducted every two years to review newly available literature and draw conclusions from the overall evidence.Veterans and Agent Orange: Update 2012 reviews peer-reviewed scientific reports concerning associations between health outcomes and exposure to TCDD and other chemicals in the herbicides used in Vietnam that were published in October 2010--September 2012 and integrates this information with the previously established evidence database. This report considers whether a statistical association with herbicide exposure exists, taking into account the strength of the scientific evidence and the appropriateness of the statistical and epidemiological methods used to detect the association; the increased risk of disease among those exposed to herbicides during service in the Republic of Vietnam during the Vietnam era; and whether there exists a plausible biological mechanism or other evidence of a causal relationship between herbicide exposure and the disease Summary -- 1. Introduction -- 2. Evaluating the evidence -- 3. Exposure to the herbicides used in Vietnam -- 4. Information related to biologic plausibility -- 5. Epidemiologic studies: compendium of new publications -- 6. Epidemiologic studies: background on multiply referenced populations -- 7. Immune-system disorders -- 8. Cancer -- 9. Fertility and gestational outcomes -- 10. Effects on future generations -- 11. Neurologic disorders -- 12. Cardiovascular and metabolic outcomes -- 13. Other chronic health outcomes -- 14. Conclusions and recommendations -- Appendix A: Issues raised by the public and agendas of public meetings held by the Commitee to Review the Health Effects in Vietnam Veterans of Exposure to Herbicides (Ninth Biennial Update) and other written submissions to the Committee -- Appendix B: Short-term adverse health responses -- Appendix C: Clarification of cancer groupings used in reporting results, with correspondence to National Institute for Occupational Safety and Health and health cause-of-death codes and international classification of diseases codes for cancers -- Appendix D: Biographies of Commitee to Review the Health Effects in Vietnam Veterans of Exposure to Herbicides (Ninth Biennial Update) and staff Vietnam War (1961-1975) fast Tetrachlorodibenzodioxin / adverse effects / United States Defoliants, Chemical / adverse effects / United States Occupational Exposure / United States Veterans Health / United States Vietnam Conflict / United States MEDICAL / Toxicology bisacsh Agent Orange / Health aspects fast Agent Orange / Toxicology fast Veterans / Health risk assessment fast Medizin Vietnamkrieg Agent Orange Toxicology Vietnam War, 1961-1975 Veterans Health aspects Vietnam War, 1961-1975 Veterans Diseases Herbicides Toxicology Epidemiology |
| title | Veterans and Agent Orange update 2012 |
| title_auth | Veterans and Agent Orange update 2012 |
| title_exact_search | Veterans and Agent Orange update 2012 |
| title_full | Veterans and Agent Orange update 2012 Committee to Review the Health Effects in Vietnam Veterans of Exposure to Herbicides (Ninth Biennial Update), Board on the Health of Select Populations, Institute of Medicine |
| title_fullStr | Veterans and Agent Orange update 2012 Committee to Review the Health Effects in Vietnam Veterans of Exposure to Herbicides (Ninth Biennial Update), Board on the Health of Select Populations, Institute of Medicine |
| title_full_unstemmed | Veterans and Agent Orange update 2012 Committee to Review the Health Effects in Vietnam Veterans of Exposure to Herbicides (Ninth Biennial Update), Board on the Health of Select Populations, Institute of Medicine |
| title_short | Veterans and Agent Orange |
| title_sort | veterans and agent orange update 2012 |
| title_sub | update 2012 |
| topic | Vietnam War (1961-1975) fast Tetrachlorodibenzodioxin / adverse effects / United States Defoliants, Chemical / adverse effects / United States Occupational Exposure / United States Veterans Health / United States Vietnam Conflict / United States MEDICAL / Toxicology bisacsh Agent Orange / Health aspects fast Agent Orange / Toxicology fast Veterans / Health risk assessment fast Medizin Vietnamkrieg Agent Orange Toxicology Vietnam War, 1961-1975 Veterans Health aspects Vietnam War, 1961-1975 Veterans Diseases Herbicides Toxicology Epidemiology |
| topic_facet | Vietnam War (1961-1975) Tetrachlorodibenzodioxin / adverse effects / United States Defoliants, Chemical / adverse effects / United States Occupational Exposure / United States Veterans Health / United States Vietnam Conflict / United States MEDICAL / Toxicology Agent Orange / Health aspects Agent Orange / Toxicology Veterans / Health risk assessment Medizin Vietnamkrieg Agent Orange Toxicology Vietnam War, 1961-1975 Veterans Health aspects Vietnam War, 1961-1975 Veterans Diseases Herbicides Toxicology Epidemiology USA |
| url | http://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&db=nlabk&AN=867988 |
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