Predictive Methods in Percutaneous Absorption:
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Electronic eBook |
| Language: | English |
| Published: |
Berlin, Heidelberg
Springer
2015
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| Subjects: | |
| Online Access: | TUM01 UBT01 Volltext Inhaltsverzeichnis Abstract |
| Physical Description: | 1 Online-Ressource (XV, 199 p. 16 illus., 8 illus. in color) |
| ISBN: | 9783662473719 |
| DOI: | 10.1007/978-3-662-47371-9 |
Staff View
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Record in the Search Index
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| adam_text | PREDICTIVE METHODS IN PERCUTANEOUS ABSORPTION
/ MOSS, GARY P.
: 2015
TABLE OF CONTENTS / INHALTSVERZEICHNIS
SKIN STRUCTURE AND PHYSIOLOGY
METHODS FOR THE MEASUREMENT OF PERCUTANEOUS ABSORPTION
MATHEMATICAL TREATMENTS AND EARLY MODELS OF SKIN PERMEABILITY
“BUILDING ERROR UPON ERROR”: THE NEW BREADTH OF RESEARCH IN THE
FIELD
ALGORITHMS FOR ESTIMATING PERMEABILITY ACROSS ARTIFICIAL MEMBRANES
OTHER APPROACHES TO MODELLING PERCUTANEOUS ABSORPTION
“SQUIGGLY LINES AND RANDOM DOTS – YOU CAN FIT ANYTHING WITH A
NON-LINEAR MODEL”
FINITE-DOSE MODELS OF TRANSIENT EXPOSURES AND VOLATILE FORMULATION
COMPONENTS
“THE DEVIL IS IN THE DETAIL …”
CONCLUSIONS AND RECOMMENDATIONS FOR MODEL DEVELOPMENT AND USE
DIESES SCHRIFTSTUECK WURDE MASCHINELL ERZEUGT.
PREDICTIVE METHODS IN PERCUTANEOUS ABSORPTION
/ MOSS, GARY P.
: 2015
ABSTRACT / INHALTSTEXT
THIS BOOK SHEDS NEW LIGHT ON THE DEVELOPMENT AND USE OF QUANTITATIVE
MODELS TO DESCRIBE THE PROCESS OF SKIN PERMEATION. IT CRITICALLY REVIEWS
THE DEVELOPMENT OF QUANTITATIVE PREDICTIVE MODELS OF SKIN ABSORPTION AND
DISCUSSES KEY RECOMMENDATIONS FOR MODEL DEVELOPMENT. TOPICS PRESENTED
INCLUDE AN INTRODUCTION TO SKIN PHYSIOLOGY; THE UNDERLYING THEORIES OF
SKIN ABSORPTION; THE PHYSICAL LABORATORY-BASED PROCESSES USED TO
GENERATE SKIN ABSORPTION DATA, WHICH IS IN TURN USED TO CONSTRUCT
MATHEMATICAL MODELS DESCRIBING THE SKIN PERMEATION PROCESS; ALGORITHMS
OF SKIN PERMEABILITY INCLUDING QUANTITATIVE STRUCTURE-ACTIVITY (OR
PERMEABILITY) RELATIONSHIPS (QSARS OR QSPRS); RELATIONSHIPS BETWEEN
PERMEABILITY AND MOLECULAR PROPERTIES; THE DEVELOPMENT OF
FORMULATION-FOCUSED APPROACHES TO MODELS OF SKIN PERMEABILITY
PREDICTION; THE USE OF ARTIFICIAL MEMBRANES, E.G. POLYDIMETHYLSILOXANE
AS ALTERNATIVES TO MAMMALIAN SKIN; AND LASTLY, THE USE OF NOVEL MACHINE
LEARNING METHODS IN DEVELOPING THE NEXT GENERATION OF PREDICTIVE SKIN
PERMEABILITY MODELS. THE BOOK WILL BE OF INTEREST TO ALL RESEARCHERS IN
ACADEMIA AND INDUSTRY WORKING IN PHARMACEUTICAL DISCOVERY AND
DEVELOPMENT, AS WELL AS READERS FROM THE FIELD OF OCCUPATIONAL EXPOSURE
AND RISK ASSESSMENT, ESPECIALLY THOSE WHOSE WORK INVOLVES AGROCHEMICALS,
BULK CHEMICALS AND COSMETICS
DIESES SCHRIFTSTUECK WURDE MASCHINELL ERZEUGT.
|
| any_adam_object | 1 |
| author | Moss, Gary P. Gullick, Darren R. Wilkinson, Simon C. |
| author_facet | Moss, Gary P. Gullick, Darren R. Wilkinson, Simon C. |
| author_role | aut aut aut |
| author_sort | Moss, Gary P. |
| author_variant | g p m gp gpm d r g dr drg s c w sc scw |
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| dewey-full | 615 |
| dewey-hundreds | 600 - Technology (Applied sciences) |
| dewey-ones | 615 - Pharmacology and therapeutics |
| dewey-raw | 615 |
| dewey-search | 615 |
| dewey-sort | 3615 |
| dewey-tens | 610 - Medicine and health |
| discipline | Chemie / Pharmazie Biologie Medizin |
| doi_str_mv | 10.1007/978-3-662-47371-9 |
| format | Electronic eBook |
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| indexdate | 2024-07-10T07:08:23Z |
| institution | BVB |
| isbn | 9783662473719 |
| language | English |
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| physical | 1 Online-Ressource (XV, 199 p. 16 illus., 8 illus. in color) |
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| spelling | Moss, Gary P. Verfasser aut Predictive Methods in Percutaneous Absorption Gary P. Moss, Darren R. Gullick, Simon C. Wilkinson Berlin, Heidelberg Springer 2015 1 Online-Ressource (XV, 199 p. 16 illus., 8 illus. in color) txt rdacontent c rdamedia cr rdacarrier Medicine Human physiology Toxicology Dermatology Physiology / Mathematics Biomedicine Pharmacology/Toxicology Human Physiology Physiological, Cellular and Medical Topics Mathematik Medizin Gullick, Darren R. Verfasser aut Wilkinson, Simon C. Verfasser aut Erscheint auch als Druckausgabe 978-3-662-47370-2 https://doi.org/10.1007/978-3-662-47371-9 Verlag Volltext Springer Fremddatenuebernahme application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=028161185&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis Springer Fremddatenuebernahme application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=028161185&sequence=000003&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA Abstract |
| spellingShingle | Moss, Gary P. Gullick, Darren R. Wilkinson, Simon C. Predictive Methods in Percutaneous Absorption Medicine Human physiology Toxicology Dermatology Physiology / Mathematics Biomedicine Pharmacology/Toxicology Human Physiology Physiological, Cellular and Medical Topics Mathematik Medizin |
| title | Predictive Methods in Percutaneous Absorption |
| title_auth | Predictive Methods in Percutaneous Absorption |
| title_exact_search | Predictive Methods in Percutaneous Absorption |
| title_full | Predictive Methods in Percutaneous Absorption Gary P. Moss, Darren R. Gullick, Simon C. Wilkinson |
| title_fullStr | Predictive Methods in Percutaneous Absorption Gary P. Moss, Darren R. Gullick, Simon C. Wilkinson |
| title_full_unstemmed | Predictive Methods in Percutaneous Absorption Gary P. Moss, Darren R. Gullick, Simon C. Wilkinson |
| title_short | Predictive Methods in Percutaneous Absorption |
| title_sort | predictive methods in percutaneous absorption |
| topic | Medicine Human physiology Toxicology Dermatology Physiology / Mathematics Biomedicine Pharmacology/Toxicology Human Physiology Physiological, Cellular and Medical Topics Mathematik Medizin |
| topic_facet | Medicine Human physiology Toxicology Dermatology Physiology / Mathematics Biomedicine Pharmacology/Toxicology Human Physiology Physiological, Cellular and Medical Topics Mathematik Medizin |
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