Hyperbranched Polydendrons: A New Macromolecular Architecture
Saved in:
| Main Author: | |
|---|---|
| Format: | Thesis Electronic eBook |
| Language: | English |
| Published: |
Cham [u.a.]
Springer International Publishing
2015
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| Series: | Springer Theses, Recognizing Outstanding Ph.D. Research
|
| Subjects: | |
| Online Access: | FAW01 UBT01 Volltext Inhaltsverzeichnis Abstract |
| Physical Description: | 1 Online-Ressource (XXII, 260 p. 218 illus., 9 illus. in color) |
| ISBN: | 9783319187532 |
| DOI: | 10.1007/978-3-319-18753-2 |
Staff View
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Record in the Search Index
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| adam_text | HYPERBRANCHED POLYDENDRONS
/ HATTON, FIONA L.
: 2015
TABLE OF CONTENTS / INHALTSVERZEICHNIS
INTRODUCTION
SYNTHESIS AND CHARACTERISATION OF HYP-POLYDENDRON MATERIALS AND
SUBSEQUENT ANOPARTICLE FORMATION
MIXING DENDRON AND PEG INITIATORS FOR THE POLYMERISATION OF BRANCHED
PHPMA AND AQUEOUS NANOPARTICLE FORMATION
MIXING DENDRON AND PEG INITIATORS FOR THE POLYMERISATION OF BRANCHED
PHPMA AND FORMATION OF STERICALLY STABILISED NANOPARTICLES
HYP-POLYDENDRONS; STUDIES OF NANOPRECIPITATION BEHAVIOR
CONCLUSIONS AND FUTURE WORK
EXPERIMENTAL
DIESES SCHRIFTSTUECK WURDE MASCHINELL ERZEUGT.
HYPERBRANCHED POLYDENDRONS
/ HATTON, FIONA L.
: 2015
ABSTRACT / INHALTSTEXT
THIS THESIS OUTLINES THE FIRST SYNTHESIS OF A NEW COMPLEX BRANCHED
POLYMER ARCHITECTURE THAT AIMS TO COMBINE THE BENEFITS OF DENDRIMERS
WITH THE SIMPLICITY OF CONVENTIONAL POLYMERISATION. THERE IS NO OTHER
AVAILABLE LITERATURE ON THESE REMARKABLE MATERIALS, DUBBED HYPERBRANCHED
POLYDENDRONS, DUE TO THEIR NOVELTY. THE NEW MATERIALS WERE SHOWN TO HAVE
VERY HIGH MOLECULAR WEIGHTS ( 1,000,000 G/MOL), EXCEPTIONAL
SELF-ASSEMBLY AND ENCAPSULATION BEHAVIOUR AND UNPARALLELED
FUNCTIONALISATION CAPABILITIES, AND WERE STUDIED PHARMACOLOGICALLY TO
DETERMINE THEIR POTENTIAL AS ORAL NANOMEDICINE CANDIDATES. THE DETAILED
INVESTIGATION OF THE CHEMICAL VARIABLES INVOLVED IN SYNTHESISING
HYPERBRANCHED POLYDENDRONS HAS SHOWN THAT THEIR SELF-ASSEMBLY AND
PHARMACOLOGICAL BEHAVIOUR CAN BE TURNED ON AND OFF AND FINE-TUNED BY
ALTERING THE COMPOSITION OF THE MATERIALS. THE PERMEATION OF THE
SELF-ASSEMBLED PARTICLES THROUGH MODEL GUT EPITHELIUM SUGGESTS THE
POTENTIAL FOR ORAL DOSING OF DRUG LOADED NANOMEDICINES THAT RESULT IN
CIRCULATING NANOPARTICLES – A RESEARCH GOAL THAT IS CURRENTLY BEING
PURSUED BY SEVERAL GROUPS AROUND THE GLOBE
DIESES SCHRIFTSTUECK WURDE MASCHINELL ERZEUGT.
|
| any_adam_object | 1 |
| author | Hatton, Fiona L. |
| author_facet | Hatton, Fiona L. |
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| author_sort | Hatton, Fiona L. |
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| dewey-full | 615.19 |
| dewey-hundreds | 600 - Technology (Applied sciences) |
| dewey-ones | 615 - Pharmacology and therapeutics |
| dewey-raw | 615.19 |
| dewey-search | 615.19 |
| dewey-sort | 3615.19 |
| dewey-tens | 610 - Medicine and health |
| discipline | Medizin |
| doi_str_mv | 10.1007/978-3-319-18753-2 |
| format | Thesis Electronic eBook |
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| spelling | Hatton, Fiona L. Verfasser aut Hyperbranched Polydendrons A New Macromolecular Architecture Fiona L. Hatton Cham [u.a.] Springer International Publishing 2015 1 Online-Ressource (XXII, 260 p. 218 illus., 9 illus. in color) txt rdacontent c rdamedia cr rdacarrier Springer Theses, Recognizing Outstanding Ph.D. Research Zugl.: Liverpool, Univ., Diss. Chemistry Polymers Biochemistry Nanochemistry Medicinal Chemistry Polymer Sciences Chemie (DE-588)4113937-9 Hochschulschrift gnd-content Erscheint auch als Druckausgabe 978-3-319-18752-5 https://doi.org/10.1007/978-3-319-18753-2 Verlag Volltext Springer Fremddatenuebernahme application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=028025509&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis Springer Fremddatenuebernahme application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=028025509&sequence=000003&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA Abstract |
| spellingShingle | Hatton, Fiona L. Hyperbranched Polydendrons A New Macromolecular Architecture Chemistry Polymers Biochemistry Nanochemistry Medicinal Chemistry Polymer Sciences Chemie |
| subject_GND | (DE-588)4113937-9 |
| title | Hyperbranched Polydendrons A New Macromolecular Architecture |
| title_auth | Hyperbranched Polydendrons A New Macromolecular Architecture |
| title_exact_search | Hyperbranched Polydendrons A New Macromolecular Architecture |
| title_full | Hyperbranched Polydendrons A New Macromolecular Architecture Fiona L. Hatton |
| title_fullStr | Hyperbranched Polydendrons A New Macromolecular Architecture Fiona L. Hatton |
| title_full_unstemmed | Hyperbranched Polydendrons A New Macromolecular Architecture Fiona L. Hatton |
| title_short | Hyperbranched Polydendrons |
| title_sort | hyperbranched polydendrons a new macromolecular architecture |
| title_sub | A New Macromolecular Architecture |
| topic | Chemistry Polymers Biochemistry Nanochemistry Medicinal Chemistry Polymer Sciences Chemie |
| topic_facet | Chemistry Polymers Biochemistry Nanochemistry Medicinal Chemistry Polymer Sciences Chemie Hochschulschrift |
| url | https://doi.org/10.1007/978-3-319-18753-2 http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=028025509&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=028025509&sequence=000003&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA |
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