Verfügbarkeit: Pharmacology of Itch

Pharmacology of Itch:

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Bibliographische Detailangaben
Weitere Verfasser:	Yosipovitch, Gil (HerausgeberIn)
Format:	Elektronisch E-Book
Sprache:	English
Veröffentlicht:	Berlin, Heidelberg Springer 2015
Schriftenreihe:	Handbook of Experimental Pharmacology 226
Schlagworte:	Medicine Immunology Toxicology Allergy Anesthesiology Dermatology Pain Medicine Biomedicine Pharmacology/Toxicology Allergology Medizin
Online-Zugang:	FUBA2 TUM01 UBT01 URL des Erstveröffentlichers Inhaltsverzeichnis Abstract
Beschreibung:	1 Online-Ressource (VIII, 382 S.) Ill., graph. Darst.
ISBN:	9783662446058
DOI:	10.1007/978-3-662-44605-8

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Datensatz im Suchindex

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adam_text	PHARMACOLOGY OF ITCH / COWAN, ALAN : 2015 TABLE OF CONTENTS / INHALTSVERZEICHNIS HISTORICAL BACKGROUND EPIDEMIOLOGY OF THE BURDEN OF CHRONIC ITCH NEUROPHYSIOLOGY AND ITCH PATHWAYS BRAIN MECHANISMS OF CHRONIC ITCH MOUSE AND HUMAN MODELS OF ITCH. TRANSIENT RECEPTOR POTENTIAL CHANNELS AND ITCH CYTOKINES AND ITCH ROLE OF MRGPR FAMILY OF RECEPTORS AND ITCH PROTEASE-ACTIVATED RECEPTOR AGONISTS AND ITCH VGLUT2-DEPENDENT SENSORY NEURONS AND ITCH IDENTIFICATION AND CHARACTERIZATION OF SPINAL INHIBITORY NEURONS THAT INHIBIT ITCH NORADRENERGIC ITCH TRANSMISSION IN THE SPINAL CORD NK-1 ANTAGONISTS AND ITCH CANNABINOIDS AND ITCH ANTIHISTAMINES AND ITCH TARGETING ITCH WITH LIGANDS SELECTIVE FOR K OPIOID RECEPTORS NEURAXIAL OPIOID-INDUCED SCRATCHING AND ITS PHARMACOLOGICAL ANTAGONISM TOPICAL THERAPIES ALLERGIC ITCH IN DOGS DIESES SCHRIFTSTUECK WURDE MASCHINELL ERZEUGT. PHARMACOLOGY OF ITCH / COWAN, ALAN : 2015 ABSTRACT / INHALTSTEXT BASIC RESEARCH ON THE PHARMACOLOGY OF ITCH HAS EXPLODEDIN THE WAKEOF TWO VERY INFLUENTIAL PAPERS THAT WERE PUBLISHED IN NATURE (2007) AND SCIENCE (2009). LONG OVERLOOKED AS A MILDER FORM OF PAIN, ITCHING HAS RAPIDLY GAINED A NEW APPRECIATION IN BOTH RESEARCH AND CLINICAL COMMUNITIES BECAUSE OF ITS COMPLEXITY AND ITS NEGATIVE EFFECTS ON THE QUALITY OF LIFE OF THE DISTRESSED PATIENTS. LIKE PAIN, NOT ALL ITCHES ARE THE SAME. UNLIKE PAIN, THERE ARE NO STANDARD DRUGS EQUIVALENT TO ASPIRIN AND MORPHINE. EPIDEMIOLOGICAL STUDIES EMPHASIZE THE HIGH INCIDENCE AND ECONOMIC COSTS OF ITCH (PRURITUS). IT IS THE MOST PREVALENT SYMPTOM OF A WIDE VARIETY OF ALLERGIC AND INFLAMMATORY SKIN CONDITIONS (E.G., PSORIASIS, ATOPIC DERMATITIS), IS ASSOCIATED WITH SEVERAL SYSTEMIC DISEASES (E.G., CHRONIC KIDNEY AND LIVER DISEASE), AND OCCURS IN PATIENTS UNDERGOING HEMODIALYSIS, SPINAL ADMINISTRATION OF OPIOIDS, AND IN THOSE SUFFERING FROM AIDS. THE READER WILL LEARN ABOUT THE MULTIPLE PATHWAYS FOR ITCH AND THEIR INTERACTIONS WITH PAIN. THE RELATIONSHIP BETWEEN THESE CLOSELY RELATED, YET DISTINCT SENSORY PHENOMENA, WILL BE EMPHASIZED. BOTH ITCH AND PAIN USE SEVERAL COMMON MOLECULES TO SEND SIGNALS TO THE BRAIN. THUS, DRUGS THAT HAVE BEEN, AND ARE BEING, DEVELOPED AS ANALGESICS MAY ALSO ATTENUATE INTRACTABLE ITCH. THIS HAS BEEN AN EXCITING AND VERY NECESSARY TURN OF EVENTS SINCE TRADITIONAL H-1 RECEPTOR ANTAGONISTS ARE INEFFECTIVE IN BLOCKING THE PRURITUS ASSOCIATED WITH KIDNEY FAILURE AND CHOLESTASIS. THE CLINICAL CHAPTERS WILL PROVIDE INSIGHTS INTO CONTEMPORARY TREATMENT REGIMENS FOR PRURITUS IN DIFFERENT HUMAN SCENARIOS DIESES SCHRIFTSTUECK WURDE MASCHINELL ERZEUGT.
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spelling	Pharmacology of Itch Alan Cowan, Gil Yosipovitch, ed. Berlin, Heidelberg Springer 2015 1 Online-Ressource (VIII, 382 S.) Ill., graph. Darst. txt rdacontent c rdamedia cr rdacarrier Handbook of Experimental Pharmacology 226 Medicine Immunology Toxicology Allergy Anesthesiology Dermatology Pain Medicine Biomedicine Pharmacology/Toxicology Allergology Medizin Cowan, Alan 1942- Sonstige (DE-588)172034701 oth Yosipovitch, Gil edt Erscheint auch als Druck-Ausgabe 978-3-662-44604-1 Handbook of Experimental Pharmacology 226 (DE-604)BV041417603 226 https://doi.org/10.1007/978-3-662-44605-8 Verlag URL des Erstveröffentlichers Volltext Springer Fremddatenuebernahme application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=027978819&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis Springer Fremddatenuebernahme application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=027978819&sequence=000003&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA Abstract
spellingShingle	Pharmacology of Itch Handbook of Experimental Pharmacology Medicine Immunology Toxicology Allergy Anesthesiology Dermatology Pain Medicine Biomedicine Pharmacology/Toxicology Allergology Medizin
title	Pharmacology of Itch
title_auth	Pharmacology of Itch
title_exact_search	Pharmacology of Itch
title_full	Pharmacology of Itch Alan Cowan, Gil Yosipovitch, ed.
title_fullStr	Pharmacology of Itch Alan Cowan, Gil Yosipovitch, ed.
title_full_unstemmed	Pharmacology of Itch Alan Cowan, Gil Yosipovitch, ed.
title_short	Pharmacology of Itch
title_sort	pharmacology of itch
topic	Medicine Immunology Toxicology Allergy Anesthesiology Dermatology Pain Medicine Biomedicine Pharmacology/Toxicology Allergology Medizin
topic_facet	Medicine Immunology Toxicology Allergy Anesthesiology Dermatology Pain Medicine Biomedicine Pharmacology/Toxicology Allergology Medizin
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work_keys_str_mv	AT cowanalan pharmacologyofitch AT yosipovitchgil pharmacologyofitch

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