Principles of molecular virology:
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| Main Author: | |
|---|---|
| Format: | Book |
| Language: | English |
| Published: |
Amsterdam [u.a.]
Acad. Press
2016
|
| Edition: | 6. ed. |
| Subjects: | |
| Online Access: | Inhaltsverzeichnis |
| Item Description: | Literaturangaben |
| Physical Description: | IX, 308 S. Ill., graph. Darst. |
| ISBN: | 9780128019467 |
Staff View
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Record in the Search Index
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| adam_text | Titel: Principles of molecular virology
Autor: Cann, Alan J
Jahr: 2016
Contents
PREFACE TO THE SIXTH EDITION....................................................................
CHAPTER 1 Introduction...............................................................................
What Are Viruses?................................................................................
Are Viruses Alive?.................................................................................
The History of Virology.........................................................................
Living Host Systems.............................................................................
Cell Culture Methods...........................................................................
Serological/Immunological Methods..................................................
Ultrastructural Studies......................................................................1
Molecular Biology...............................................................................1
Further Reading..................................................................................2
CHAPTER 2 Particles...................................................................................2
The Function and Formation of Virus Particles...............................2
Capsid Symmetry and Virus Architecture........................................2
Helical Capsids...................................................................................3
Icosahedral (Isometric) Capsids........................................................3
Enveloped Viruses..............................................................................4
Complex Virus Structures..................................................................4
Protein—Nucleic Acid Interactions and Genome Packaging...........5
Virus Receptors: Recognition and Binding.......................................5
Other Interactions of the Virus Capsid with the Host Cell..............5
Summary.............................................................................................5
Further Reading..................................................................................5
CHAPTER 3 Genomes..................................................................................5
The Structure and Complexity of Virus Genomes............................5
Molecular Genetics.............................................................................6
Virus Genetics.....................................................................................6
Virus Mutants
Contents
Genetic Interactions between Viruses...............................................69
Nongenetic Interactions between Viruses........................................72
Small DNA Genomes..........................................................................76
Large DNA Genomes..........................................................................78
Positive-Strand RNA Viruses.............................................................81
Picornaviruses...............................................................................82
Togaviruses....................................................................................83
Flavivi ruses....................................................................................83
Coronavi ruses................................................................................83
Positive-Sense RNA Plant Viruses...............................................86
Negative-Strand RNA Viruses...........................................................85
Bunyaviruses..................................................................................86
Arenaviruses..................................................................................86
Orthomyxoviruses..........................................................................87
Paramyxoviruses............................................................................87
Rhabdovi ruses................................................................................87
Segmented and Multipartite Virus Genomes...................................87
Reverse Transcription and Transposition.........................................91
The Virome—Evolution and Epidemiology......................................100
Summary...........................................................................................103
Further Reading................................................................................103
CHAPTER A Replication.............................................................................105
Overview of Virus Replication..........................................................105
Investigation of Virus Replication....................................................106
The Replication Cycle.......................................................................112
Attachment...................................................................................112
Penetration...................................................................................118
Uncoating......................................................................................120
Genome Replication and Gene Expression................................122
Assembly......................................................................................127
Maturation....................................................................................128
Release.........................................................................................130
Summary...........................................................................................132
Further Reading................................................................................133
CHAPTERS Expression.............................................................................135
Expression of Genetic Information..................................................135
Control of Prokaryote Gene Expression.........................................136
Control of Expression in Bacteriophage ......................................137
Control of Eukaryote Gene Expression...........................................162
Contents
Genome Coding Strategies..............................................................145
Class I: Double-Stranded DNA...................................................145
Class II: Single-Stranded DNA...................................................148
Class III: Double-Stranded RNA.................................................149
Class IV: Single-Stranded (+)Sense RNA..................................151
Class V: Single-Stranded HSense RNA....................................154
Class VI: Single-Stranded (+)Sense RNA with DNA
Intermediate.................................................................................156
Class VII: Double-Stranded DNA with RNA
Intermediate.................................................................................156
Transcriptional Control of Expression............................................157
Posttranscriptional Control of Expression.....................................161
Summary...........................................................................................170
Further Reading................................................................................170
CHAPTER 6 Infection.................................................................................173
Virus Infections of Plants.................................................................173
Immune Responses to Virus Infections in Animals.......................178
Viruses and Apoptosis......................................................................183
Interferons.........................................................................................185
Evasion of Immune Responses by Viruses.....................................190
Inhibition of MHC-I-Restricted Antigen Presentation...............191
Inhibition of MHC-ll-Restricted Antigen Presentation..............191
Inhibition of NK Cell Lysis..........................................................191
Interference with Apoptosis........................................................191
Inhibition of Cytokine Action.......................................................191
Evasion of Humoral Immunity....................................................192
Evasion of the Complement Cascade........................................192
Virus—Host Interactions...................................................................192
The Course of Virus Infections........................................................202
Abortive Infection.........................................................................202
Acute Infection.............................................................................202
Chronic Infection..........................................................................202
Persistent Infection.....................................................................202
Latent Infection............................................................................204
Prevention and Therapy of Virus Infection.....................................205
RNA Interference..............................................................................209
Viruses as Therapeutics...................................................................212
Chemotherapy of Virus Infections...................................................214
Summary...........................................................................................219
Further Reading................................................................................219
Contents
CHAPTER 7 Pathogenesis.........................................................................221
Mechanisms of Cellular Injury........................................................222
Viruses and Immunodeficiency........................................................225
Virus-Related Diseases....................................................................230
Bacteriophages and Human Disease..............................................233
Cell Transformation by Viruses.......................................................234
Cell Transformation by Retroviruses..............................................239
Cell Transformation by DNA Viruses..............................................241
Viruses and Cancer..........................................................................244
New and Emergent Viruses.............................................................249
Zoonoses............................................................................................256
Bioterrorism......................................................................................257
Summary...........................................................................................258
Further Reading................................................................................258
CHAPTER 8 Subviral Agents: Genomes without Viruses, Viruses
without Genomes..................................................................261
Satellites and Viroids........................................................................261
Prions.................................................................................................265
Pathology of Prion Diseases............................................................266
TSE in Animals..................................................................................266
Scrapie..........................................................................................266
Transmissible Mink Encephalopathy (TME]..............................268
Feline Spongiform Encephalopathy (FSE).................................268
Chronic Wasting Disease (CWD].................................................268
Bovine Spongiform Encephalopathy...........................................269
Human TSEs......................................................................................270
Molecular Biology of Prions.............................................................273
Summary...........................................................................................279
Further Reading................................................................................279
APPENDIX 1: GLOSSARY AND ABBREVIATIONS........................................281
APPENDIX 2: CLASSIFICATION OF SUBCELLULAR
INFECTIOUS AGENTS.............................................................291
APPENDIX 3: THE HISTORY OF VIROLOGY..................................................295
INDEX..............................................................................................................301
|
| any_adam_object | 1 |
| author | Cann, Alan ca. 20./21. Jh |
| author_GND | (DE-588)1089177542 |
| author_facet | Cann, Alan ca. 20./21. Jh |
| author_role | aut |
| author_sort | Cann, Alan ca. 20./21. Jh |
| author_variant | a c ac |
| building | Verbundindex |
| bvnumber | BV042370528 |
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| ctrlnum | (OCoLC)909805170 (DE-599)BVBBV042370528 |
| dewey-full | 579.2 |
| dewey-hundreds | 500 - Natural sciences and mathematics |
| dewey-ones | 579 - Microorganisms, fungi & algae |
| dewey-raw | 579.2 |
| dewey-search | 579.2 |
| dewey-sort | 3579.2 |
| dewey-tens | 570 - Biology |
| discipline | Biologie Medizin |
| edition | 6. ed. |
| format | Book |
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| spelling | Cann, Alan ca. 20./21. Jh. Verfasser (DE-588)1089177542 aut Principles of molecular virology Alan J. Cann 6. ed. Amsterdam [u.a.] Acad. Press 2016 IX, 308 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Literaturangaben Maladies virales Maladies à virus - Aspect moléculaire ram Virologie moléculaire Virologie moléculaire ram Virologie Virus - Aspect moléculaire ram Molekulare Virologie (DE-588)4170393-5 gnd rswk-swf Molekularbiologie (DE-588)4039983-7 gnd rswk-swf Molekulargenetik (DE-588)4039987-4 gnd rswk-swf Virologie (DE-588)4063597-1 gnd rswk-swf Viren (DE-588)4063589-2 gnd rswk-swf (DE-588)4151278-9 Einführung gnd-content Viren (DE-588)4063589-2 s Molekulargenetik (DE-588)4039987-4 s DE-604 Molekularbiologie (DE-588)4039983-7 s Molekulare Virologie (DE-588)4170393-5 s Virologie (DE-588)4063597-1 s 1\p DE-604 HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=027806796&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis 1\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk |
| spellingShingle | Cann, Alan ca. 20./21. Jh Principles of molecular virology Maladies virales Maladies à virus - Aspect moléculaire ram Virologie moléculaire Virologie moléculaire ram Virologie Virus - Aspect moléculaire ram Molekulare Virologie (DE-588)4170393-5 gnd Molekularbiologie (DE-588)4039983-7 gnd Molekulargenetik (DE-588)4039987-4 gnd Virologie (DE-588)4063597-1 gnd Viren (DE-588)4063589-2 gnd |
| subject_GND | (DE-588)4170393-5 (DE-588)4039983-7 (DE-588)4039987-4 (DE-588)4063597-1 (DE-588)4063589-2 (DE-588)4151278-9 |
| title | Principles of molecular virology |
| title_auth | Principles of molecular virology |
| title_exact_search | Principles of molecular virology |
| title_full | Principles of molecular virology Alan J. Cann |
| title_fullStr | Principles of molecular virology Alan J. Cann |
| title_full_unstemmed | Principles of molecular virology Alan J. Cann |
| title_short | Principles of molecular virology |
| title_sort | principles of molecular virology |
| topic | Maladies virales Maladies à virus - Aspect moléculaire ram Virologie moléculaire Virologie moléculaire ram Virologie Virus - Aspect moléculaire ram Molekulare Virologie (DE-588)4170393-5 gnd Molekularbiologie (DE-588)4039983-7 gnd Molekulargenetik (DE-588)4039987-4 gnd Virologie (DE-588)4063597-1 gnd Viren (DE-588)4063589-2 gnd |
| topic_facet | Maladies virales Maladies à virus - Aspect moléculaire Virologie moléculaire Virologie Virus - Aspect moléculaire Molekulare Virologie Molekularbiologie Molekulargenetik Viren Einführung |
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