Ligand efficiency indices for drug discovery: towards an atlas-guided paradigm
Gespeichert in:
| 1. Verfasser: | |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Oxford
Elsevier
2013
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| Schlagworte: | |
| Online-Zugang: | Volltext |
| Beschreibung: | Includes bibliographical references The purpose of Ligand Efficiency Indices for Drug Discovery: Towards an Atlas-Guided Paradigm is to introduce in a concise and self-contained form the concepts, ideas, applications and examples of efficiency-driven drug discovery to the biomedical community at large. The book emphasizes the use of 'new variables' and more objective numerical methods to drive drug discovery in an encompassing way. These 'new variables' are based on Ligand Efficiency Indices (LEIs) formulated in a way that permits mapping Chemico-Biological Space (CBS) in an Atlas-like representation. It provides a practical and timely discussion of the concepts, ideas, applications and examples of efficiency-driven drug discovery. This book emphasizes the use of a graphical representation and objective numerical methods to drive drug discovery more effectively. It presents the definition of LEIs and the corresponding efficiency planes within an atlas-like environment to provide a robust graphical and numerical framework for medicinal chemists and drug-discoverers. Provides a practical and timely discussion of the concepts, ideas, applications and examples of efficiency-driven drug discoveryEmphasizes the use of 'new variables' and more objective numerical methods to drive quicker and more effective drug discoveryPresents the definition of Ligand Efficiency Indices (LEIs) and the corresponding efficiency planes as key concepts to provide a graphical and numerical framework |
| Beschreibung: | 1 Online-Ressource (xix, 158 p. :) |
| ISBN: | 9780124046825 0124046827 9780124046351 0124046355 |
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| 500 | |a The purpose of Ligand Efficiency Indices for Drug Discovery: Towards an Atlas-Guided Paradigm is to introduce in a concise and self-contained form the concepts, ideas, applications and examples of efficiency-driven drug discovery to the biomedical community at large. The book emphasizes the use of 'new variables' and more objective numerical methods to drive drug discovery in an encompassing way. These 'new variables' are based on Ligand Efficiency Indices (LEIs) formulated in a way that permits mapping Chemico-Biological Space (CBS) in an Atlas-like representation. It provides a practical and timely discussion of the concepts, ideas, applications and examples of efficiency-driven drug discovery. This book emphasizes the use of a graphical representation and objective numerical methods to drive drug discovery more effectively. It presents the definition of LEIs and the corresponding efficiency planes within an atlas-like environment to provide a robust graphical and numerical framework for medicinal chemists and drug-discoverers. Provides a practical and timely discussion of the concepts, ideas, applications and examples of efficiency-driven drug discoveryEmphasizes the use of 'new variables' and more objective numerical methods to drive quicker and more effective drug discoveryPresents the definition of Ligand Efficiency Indices (LEIs) and the corresponding efficiency planes as key concepts to provide a graphical and numerical framework | ||
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Datensatz im Suchindex
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|---|---|
| any_adam_object | |
| author | Abad Zapatero, Celerino |
| author_facet | Abad Zapatero, Celerino |
| author_role | aut |
| author_sort | Abad Zapatero, Celerino |
| author_variant | z c a zc zca |
| building | Verbundindex |
| bvnumber | BV042318159 |
| collection | ZDB-33-ESD ZDB-33-EBS |
| ctrlnum | (OCoLC)828743338 (DE-599)BVBBV042318159 |
| dewey-full | 615.19 |
| dewey-hundreds | 600 - Technology (Applied sciences) |
| dewey-ones | 615 - Pharmacology and therapeutics |
| dewey-raw | 615.19 |
| dewey-search | 615.19 |
| dewey-sort | 3615.19 |
| dewey-tens | 610 - Medicine and health |
| discipline | Medizin |
| format | Electronic eBook |
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| id | DE-604.BV042318159 |
| illustrated | Not Illustrated |
| indexdate | 2024-07-10T01:18:18Z |
| institution | BVB |
| isbn | 9780124046825 0124046827 9780124046351 0124046355 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-027755150 |
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| spelling | Abad Zapatero, Celerino Verfasser aut Ligand efficiency indices for drug discovery towards an atlas-guided paradigm Celerino Abad-Zapatero Oxford Elsevier 2013 1 Online-Ressource (xix, 158 p. :) txt rdacontent c rdamedia cr rdacarrier Includes bibliographical references The purpose of Ligand Efficiency Indices for Drug Discovery: Towards an Atlas-Guided Paradigm is to introduce in a concise and self-contained form the concepts, ideas, applications and examples of efficiency-driven drug discovery to the biomedical community at large. The book emphasizes the use of 'new variables' and more objective numerical methods to drive drug discovery in an encompassing way. These 'new variables' are based on Ligand Efficiency Indices (LEIs) formulated in a way that permits mapping Chemico-Biological Space (CBS) in an Atlas-like representation. It provides a practical and timely discussion of the concepts, ideas, applications and examples of efficiency-driven drug discovery. This book emphasizes the use of a graphical representation and objective numerical methods to drive drug discovery more effectively. It presents the definition of LEIs and the corresponding efficiency planes within an atlas-like environment to provide a robust graphical and numerical framework for medicinal chemists and drug-discoverers. Provides a practical and timely discussion of the concepts, ideas, applications and examples of efficiency-driven drug discoveryEmphasizes the use of 'new variables' and more objective numerical methods to drive quicker and more effective drug discoveryPresents the definition of Ligand Efficiency Indices (LEIs) and the corresponding efficiency planes as key concepts to provide a graphical and numerical framework MEDICAL / Drug Guides bisacsh MEDICAL / Nursing / Pharmacology bisacsh MEDICAL / Pharmacology bisacsh MEDICAL / Pharmacy bisacsh Drug development fast Medizin Drug development http://www.sciencedirect.com/science/book/9780124046351 Verlag Volltext |
| spellingShingle | Abad Zapatero, Celerino Ligand efficiency indices for drug discovery towards an atlas-guided paradigm MEDICAL / Drug Guides bisacsh MEDICAL / Nursing / Pharmacology bisacsh MEDICAL / Pharmacology bisacsh MEDICAL / Pharmacy bisacsh Drug development fast Medizin Drug development |
| title | Ligand efficiency indices for drug discovery towards an atlas-guided paradigm |
| title_auth | Ligand efficiency indices for drug discovery towards an atlas-guided paradigm |
| title_exact_search | Ligand efficiency indices for drug discovery towards an atlas-guided paradigm |
| title_full | Ligand efficiency indices for drug discovery towards an atlas-guided paradigm Celerino Abad-Zapatero |
| title_fullStr | Ligand efficiency indices for drug discovery towards an atlas-guided paradigm Celerino Abad-Zapatero |
| title_full_unstemmed | Ligand efficiency indices for drug discovery towards an atlas-guided paradigm Celerino Abad-Zapatero |
| title_short | Ligand efficiency indices for drug discovery |
| title_sort | ligand efficiency indices for drug discovery towards an atlas guided paradigm |
| title_sub | towards an atlas-guided paradigm |
| topic | MEDICAL / Drug Guides bisacsh MEDICAL / Nursing / Pharmacology bisacsh MEDICAL / Pharmacology bisacsh MEDICAL / Pharmacy bisacsh Drug development fast Medizin Drug development |
| topic_facet | MEDICAL / Drug Guides MEDICAL / Nursing / Pharmacology MEDICAL / Pharmacology MEDICAL / Pharmacy Drug development Medizin |
| url | http://www.sciencedirect.com/science/book/9780124046351 |
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