Autophagy, Volume 1 cancer, other pathologies, inflammation, immunity, infection, and aging (Elsevier Science, 2014)
6 The Role of Autophagy in Atherosclerosis
Includes bibliographical references and index
ReferencesI General Diseases; 2 Mechanisms of Regulation of p62 in Autophagy and Implications for Health and Diseases; Introduction; LC3 Recognition by p62; Interacting Region between LC3 and p62; Overall Structure of the LC3-p62-LRS Complex; Characterization of Atg8 Homologue-LRS Domain; Role of p62 as an Autophagy Receptor; Autophagic Degradation of p62; Requirement of the PB1 Domain for p62 Degradation; Ubiquitin-and p62-Positive Inclusion Formation; Discussion; References; 3 Molecular Mechanisms Underlying the Role of Autophagy in Neurodegenerative Diseases; Autophagy Overview and Types
Understanding the importance and necessity of the role of autophagy in health and disease is vital for the studies of cancer, aging, neurodegeneration, immunology, and infectious diseases. Comprehensive and forward thinking, these books offer a valuable guide to both cellular processes while inciting researchers to explore their potentially important connections