Optimization of chromatographic selectivity: a guide to method development
Saved in:
Main Author: | |
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Format: | Electronic eBook |
Language: | English |
Published: |
Amsterdam
Elsevier
1986
|
Series: | Journal of chromatography library
v. 35 |
Subjects: | |
Online Access: | Volltext |
Item Description: | This is the first detailed description of method development in chromatography - the overall process of which may be summarized as: method selection, phase selection, selectivity optimization, and system optimization. All four aspects receive attention in this book. Chapter 1 gives a short introduction, describes chromatographic theory and nomenclature, and outlines the method development process. Chapter 2 describes guidelines for method selection, and quantitative concepts for characterizing and classifying chromatographic phases. Selective separation methods, from both gas and liquid chromatography are given in Chapter 3; the main parameters of each method are identified and simple, quantitative relations are sought to describe their effects. Criteria by which to judge the quality of separation are discussed in Chapter 4 with clear recommendations for different situations. The specific problems involved in the optimization of chromatographic selectivity are explained in Chapter 5. Optimization procedures, illustrated by examples, are extensively described and compared on the basis of a number of criteria. Suggestions are made both for the application of different procedures and for further research. The optimization of programmed analysis receives special attention in Chapter 6, and the last chapter summarizes the optimization of the chromatographic system, including the optimization of the efficiency, sensitivity and instrumentation. Those involved in developing chromatographic methods or wishing to improve existing methods will value the detailed, structured way in which the subject is presented. Because optimization procedures and criteria are described as elements of a complete optimization package, the book will help the reader to understand, evaluate and select current and future commercial systems Includes bibliographical references and index |
Physical Description: | 1 Online-Ressource (xv, 345 p.) |
ISBN: | 9780444426819 0444426817 |
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author | Schoenmakers, Peter J. |
author_facet | Schoenmakers, Peter J. |
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spelling | Schoenmakers, Peter J. Verfasser aut Optimization of chromatographic selectivity a guide to method development Peter J. Schoenmakers Amsterdam Elsevier 1986 1 Online-Ressource (xv, 345 p.) txt rdacontent c rdamedia cr rdacarrier Journal of chromatography library v. 35 This is the first detailed description of method development in chromatography - the overall process of which may be summarized as: method selection, phase selection, selectivity optimization, and system optimization. All four aspects receive attention in this book. Chapter 1 gives a short introduction, describes chromatographic theory and nomenclature, and outlines the method development process. Chapter 2 describes guidelines for method selection, and quantitative concepts for characterizing and classifying chromatographic phases. Selective separation methods, from both gas and liquid chromatography are given in Chapter 3; the main parameters of each method are identified and simple, quantitative relations are sought to describe their effects. Criteria by which to judge the quality of separation are discussed in Chapter 4 with clear recommendations for different situations. The specific problems involved in the optimization of chromatographic selectivity are explained in Chapter 5. Optimization procedures, illustrated by examples, are extensively described and compared on the basis of a number of criteria. Suggestions are made both for the application of different procedures and for further research. The optimization of programmed analysis receives special attention in Chapter 6, and the last chapter summarizes the optimization of the chromatographic system, including the optimization of the efficiency, sensitivity and instrumentation. Those involved in developing chromatographic methods or wishing to improve existing methods will value the detailed, structured way in which the subject is presented. Because optimization procedures and criteria are described as elements of a complete optimization package, the book will help the reader to understand, evaluate and select current and future commercial systems Includes bibliographical references and index Chromatography / methods Chromatographie Chromatografie gtt Chromatographic analysis fast Chromatographic analysis Optimierung (DE-588)4043664-0 gnd rswk-swf Selektivität (DE-588)4251340-6 gnd rswk-swf Chromatographie (DE-588)4010153-8 gnd rswk-swf Methode (DE-588)4038971-6 gnd rswk-swf Chromatographie (DE-588)4010153-8 s Optimierung (DE-588)4043664-0 s Selektivität (DE-588)4251340-6 s Methode (DE-588)4038971-6 s 1\p DE-604 http://www.sciencedirect.com/science/book/9780444426819 Verlag Volltext 1\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk |
spellingShingle | Schoenmakers, Peter J. Optimization of chromatographic selectivity a guide to method development Chromatography / methods Chromatographie Chromatografie gtt Chromatographic analysis fast Chromatographic analysis Optimierung (DE-588)4043664-0 gnd Selektivität (DE-588)4251340-6 gnd Chromatographie (DE-588)4010153-8 gnd Methode (DE-588)4038971-6 gnd |
subject_GND | (DE-588)4043664-0 (DE-588)4251340-6 (DE-588)4010153-8 (DE-588)4038971-6 |
title | Optimization of chromatographic selectivity a guide to method development |
title_auth | Optimization of chromatographic selectivity a guide to method development |
title_exact_search | Optimization of chromatographic selectivity a guide to method development |
title_full | Optimization of chromatographic selectivity a guide to method development Peter J. Schoenmakers |
title_fullStr | Optimization of chromatographic selectivity a guide to method development Peter J. Schoenmakers |
title_full_unstemmed | Optimization of chromatographic selectivity a guide to method development Peter J. Schoenmakers |
title_short | Optimization of chromatographic selectivity |
title_sort | optimization of chromatographic selectivity a guide to method development |
title_sub | a guide to method development |
topic | Chromatography / methods Chromatographie Chromatografie gtt Chromatographic analysis fast Chromatographic analysis Optimierung (DE-588)4043664-0 gnd Selektivität (DE-588)4251340-6 gnd Chromatographie (DE-588)4010153-8 gnd Methode (DE-588)4038971-6 gnd |
topic_facet | Chromatography / methods Chromatographie Chromatografie Chromatographic analysis Optimierung Selektivität Methode |
url | http://www.sciencedirect.com/science/book/9780444426819 |
work_keys_str_mv | AT schoenmakerspeterj optimizationofchromatographicselectivityaguidetomethoddevelopment |