Introduction to biological and small molecule drug research and development theory and case studies (Academic Press, 2013)
The fundamental concept of the book is to provide, for the first time, an introduction to understand the science behind successful pharmaceutical research and development programs. As well as explaining the basic principles, the book compares and contrasts approaches to both biopharmaceuticals (proteins) and small molecule drugs and presents an overview of the business and management issues for these approaches. The second part of the book provides 9 carefully selected real life case studies to illustrate how the theory presented in the first part of the book is actually being put into practice. Introduction to Biological and Small Molecule Drug Research and Development is intended for late-stage undergraduates or postgraduates studying chemistry (at the biology interface), biochemistry, medicine, pharmacy, medicine or allied subjects. The book would be used as part of the reading matter for a wide variety of science degree courses, in post-graduate taught material (Masters and PhD) and as basic background reading for scientists in the pharmaceutical industry. . For the first time the fundamental principles of the science of biopharmaceutics and small molecule chemotherapeutics are discussed side-by-side at a basic level . Edited by three senior scientists with over 100 years experience in drug research who have compiled the best scientific comparison of small molecule and biopharmaceuticals approaches to new drugs . The book will be of broad interest to students of medicine, pharmacy, biochemistry and chemistry who wish to learn about drug discovery . Illustrated with key examples of important drugs that exemplify the basic principles of pharmaceutical drug research and development