Target validation in drug discovery:
Saved in:
| Format: | Electronic eBook |
|---|---|
| Language: | English |
| Published: |
Amsterdam
Academic Press
c2007
|
| Subjects: | |
| Online Access: | Volltext |
| Item Description: | This work presents a comprehensive contemporary framework for approaching target validation in drug discovery. It begins with a detailed description of new enabling technologies, including aptamers, RNA interference, functional genomics, and proteomics. The next section looks at biologic drug development with in-depth discussion of lessons learned from such well-known cases as Erbitux, Herceptin, and Avastin. Additional targets known as "second generation" drugs, which can be identified when disease pathways are validated by biologics, present new possible small molecule therapeutics and serve as the focus of the final section of the book Includes bibliographical references and index |
| Physical Description: | 1 Online-Ressource (xii, 279 p.) |
| ISBN: | 9780123693938 0123693934 9780080465975 0080465978 |
Staff View
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| dewey-ones | 615 - Pharmacology and therapeutics |
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| illustrated | Not Illustrated |
| indexdate | 2024-07-10T01:18:06Z |
| institution | BVB |
| isbn | 9780123693938 0123693934 9780080465975 0080465978 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-027749159 |
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| physical | 1 Online-Ressource (xii, 279 p.) |
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| spelling | Target validation in drug discovery editors, Brian W. Metcalf and Susan Dillon Amsterdam Academic Press c2007 1 Online-Ressource (xii, 279 p.) txt rdacontent c rdamedia cr rdacarrier This work presents a comprehensive contemporary framework for approaching target validation in drug discovery. It begins with a detailed description of new enabling technologies, including aptamers, RNA interference, functional genomics, and proteomics. The next section looks at biologic drug development with in-depth discussion of lessons learned from such well-known cases as Erbitux, Herceptin, and Avastin. Additional targets known as "second generation" drugs, which can be identified when disease pathways are validated by biologics, present new possible small molecule therapeutics and serve as the focus of the final section of the book Includes bibliographical references and index Médicaments / Développement Médicaments / Essais cliniques Criblage à haut débit (Développement des médicaments) MEDICAL / Drug Guides bisacsh MEDICAL / Pharmacology bisacsh MEDICAL / Pharmacy bisacsh MEDICAL / Nursing / Pharmacology bisacsh Médicaments / Mise au point ram Médicaments / Essais cliniques ram Criblage pharmacologique ram Drug development fast Drugs / Testing fast High throughput screening (Drug development) fast Drug Design Drug Delivery Systems Technology, Pharmaceutical Medizin Drug development Drugs Testing High throughput screening (Drug development) Metcalf, Brian W. Sonstige oth Dillon, Susan Sonstige oth http://www.sciencedirect.com/science/book/9780123693938 Verlag Volltext |
| spellingShingle | Target validation in drug discovery Médicaments / Développement Médicaments / Essais cliniques Criblage à haut débit (Développement des médicaments) MEDICAL / Drug Guides bisacsh MEDICAL / Pharmacology bisacsh MEDICAL / Pharmacy bisacsh MEDICAL / Nursing / Pharmacology bisacsh Médicaments / Mise au point ram Médicaments / Essais cliniques ram Criblage pharmacologique ram Drug development fast Drugs / Testing fast High throughput screening (Drug development) fast Drug Design Drug Delivery Systems Technology, Pharmaceutical Medizin Drug development Drugs Testing High throughput screening (Drug development) |
| title | Target validation in drug discovery |
| title_auth | Target validation in drug discovery |
| title_exact_search | Target validation in drug discovery |
| title_full | Target validation in drug discovery editors, Brian W. Metcalf and Susan Dillon |
| title_fullStr | Target validation in drug discovery editors, Brian W. Metcalf and Susan Dillon |
| title_full_unstemmed | Target validation in drug discovery editors, Brian W. Metcalf and Susan Dillon |
| title_short | Target validation in drug discovery |
| title_sort | target validation in drug discovery |
| topic | Médicaments / Développement Médicaments / Essais cliniques Criblage à haut débit (Développement des médicaments) MEDICAL / Drug Guides bisacsh MEDICAL / Pharmacology bisacsh MEDICAL / Pharmacy bisacsh MEDICAL / Nursing / Pharmacology bisacsh Médicaments / Mise au point ram Médicaments / Essais cliniques ram Criblage pharmacologique ram Drug development fast Drugs / Testing fast High throughput screening (Drug development) fast Drug Design Drug Delivery Systems Technology, Pharmaceutical Medizin Drug development Drugs Testing High throughput screening (Drug development) |
| topic_facet | Médicaments / Développement Médicaments / Essais cliniques Criblage à haut débit (Développement des médicaments) MEDICAL / Drug Guides MEDICAL / Pharmacology MEDICAL / Pharmacy MEDICAL / Nursing / Pharmacology Médicaments / Mise au point Criblage pharmacologique Drug development Drugs / Testing High throughput screening (Drug development) Drug Design Drug Delivery Systems Technology, Pharmaceutical Medizin Drugs Testing |
| url | http://www.sciencedirect.com/science/book/9780123693938 |
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