Manufacturing make or buy decision in the originating pharma industry:
Gespeichert in:
| 1. Verfasser: | |
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| Format: | Abschlussarbeit Buch |
| Sprache: | English |
| Veröffentlicht: |
[2014]
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| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | XI, 272 S. graph. Darst. |
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Datensatz im Suchindex
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| adam_text | Titel: Manufacturing make or buy decision in the originating pharma industry
Autor: Schliesing, Kathrin
Jahr: 2014
Table of contents
Table of contents......................................................................................................I
List of abbreviations and symbols.......................................................................VI
Table of figures....................................................................................................VIII
Table of tables.........................................................................................................X
1 Introduction...........................................................................................................1
1.1 Motivation of research topic...............................................................................1
1.2 Problem formulation..........................................................................................3
1.3 Objective and structure of work.........................................................................4
2 Necessity to develop a manufacturing Make or Buy decision framework for
science and practice.............................................................................................6
2.1 Introduction to the manufacturing Make or Buy phenomenon in the
originating Pharma industry...............................................................................6
2.1.1 Make or Buy phenomenon.......................................................................6
2.1.1.1 Definition and theories..................................................................6
2.1.1.2 Development and relevance.........................................................9
2.1.1.3 Functional focus..........................................................................10
2.1.2 Manufacturing Make or Buy phenomenon..............................................11
2.1.2.1 Definition and theories................................................................11
2.1.2.2 Development and relevance.......................................................12
2.1.2.3 Industry focus.............................................................................13
2.1.3 Manufacturing Make or Buy phenomenon in originating Pharma
industry...................................................................................................14
2.1.3.1 Pharma industry overview...........................................................14
2.1.3.2 Deep dive on originating Pharma industry...................................15
2.1.3.3 Manufacturing in originating Pharma industry.............................18
2.1.3.4 Manufacturing Make or Buy phenomenon in originating
Pharma industry..........................................................................19
2.2 Definition of scientific and practical manufacturing Make or Buy research
questions.........................................................................................................21
2.2.1 Manufacturing Make or Buy scientific research questions......................21
2.2.1.1 Actual state of manufacturing Make or Buy research interests
in science...................................................................................21
2.2.1.2 Selection of scientific research gaps...........................................24
2.2.1.3 Development of scientific research questions.............................25
2.2.2 Manufacturing Make or Buy practical research questions.......................27
2.2.2.1 Actual state of manufacturing Make or Buy research interests
in practice...................................................................................27
2.2.2.2 Selection of practical research gaps...........................................29
2.2.2.3 Development of practical research questions..............................30
2.2.3 Consolidation of scientific and practical research questions...................31
2.3 Summary and outlook.....................................................................................32
3 Theoretical manufacturing Make or Buy decision framework.........................34
3.1 Theoretical manufacturing Make or Buy decision tree.....................................34
3.1.1 Transaction Cost Economics and Resource Based View as theory
base.......................................................................................................34
3.1.1.1 Basic principle of Transaction Cost Economics...........................34
3.1.1.2 Basic principle of Resource Based View.....................................39
3.1.1.3 Complementarity of Transaction Cost Economics and
Resource Based View................................................................42
3.1.1.4 Contrariety of Transaction Cost Economics and Resource
Based View.................................................................................44
3.1.2 Manufacturing-specific extension of theory base....................................49
3.1.2.1 Manufacturing minimum requirements........................................49
3.1.2.2 Manufacturing-related remaining internal fixed costs..................51
3.1.3 Derivation of decision tree propositions and measures...........................54
3.1.3.1 Derivation of decision tree propositions......................................54
3.1.3.2 Derivation of decision tree measures..........................................57
3.2 Theoretical manufacturing Make or Buy decision timing..................................73
3.2.1 Outsourcing timing literature and Resource Based View as theory
base.......................................................................................................74
3.2.2 Manufacturing and originating Pharma-specific extension of theory
base.......................................................................................................77
3.2.3 Derivation of decision timing propositions and measures.......................84
3.2.3.1 Derivation of decision timing propositions...................................84
3.2.3.2 Derivation of decision timing measures.......................................87
3.3 Theoretical manufacturing Make or Buy decision tool......................................91
3.3.1 Theoretical decision tree and decision point findings as description
base.......................................................................................................91
3.3.2 Practical decision tool requirements as extension of description base....92
3.3.3 Derivation of decision tool descriptions and measures...........................94
3.3.3.1 Derivation of decision tool descriptions.......................................94
3.3.3.2 Derivation of decision tool measures........................................101
3.4 Theoretical manufacturing Make or Buy decision tool process integration.....102
3.4.1 Theoretical decision tool findings and existing decision preparation
process as description base.................................................................102
3.4.2 Derivation of decision tool process integration descriptions and
measures.............................................................................................104
3.4.2.1 Derivation of decision tool process integration descriptions......104
3.4.2.2 Derivation of decision tool process integration measures..........106
3.5 Summary and outlook...................................................................................107
4 Research strategy to validate the theoretical manufacturing Make or Buy
decision framework..........................................................................................110
4.1 Selection and design of the case study as preferred research method..........110
4.1.1 Selection of the preferred research method..........................................110
4.1.1.1 Research method selection criteria...........................................110
4.1.1.2 Research method selection.......................................................112
4.1.2 Design of the preferred research method.............................................113
4.1.2.1 Case study design criteria.........................................................113
4.1.2.2 Case study design....................................................................114
4.2 Specification of the case study data collection approach...............................117
4.2.1 Definition of data collection sources of evidence..................................117
4.2.2 Definition of data collection instances per source of evidence..............121
4.2.3 Definition of data collection procedure per source of evidence.............123
4.3 Specification of the case study data evaluation approach.............................123
4.3.1 Definition of data evaluation preparation technique..............................124
4.3.2 Definition of data evaluation technique.................................................125
4.3.3 Definition of data evaluation reporting technique..................................127
4.4 Specification of the case study research validity............................................128
4.4.1 Definition of the case study construct validity.......................................128
4.4.2 Definition of the case study internal validity..........................................129
4.4.3 Definition of the case study external validity.........................................129
4.4.4 Definition of the case study reliability....................................................130
4.5 Summary and outlook...................................................................................130
5 Evaluation of the theoretical manufacturing Make or Buy decision
framework..........................................................................................................133
5.1 Evaluation process overview.........................................................................133
5.2 Document review..........................................................................................136
5.2.1 Collection of document data.................................................................136
5.2.2 Evaluation of document data................................................................138
5.2.2.1 Document data coding..............................................................138
5.2.2.2 Document data pattern matching..............................................143
5.2.3 Document review evaluation results summary......................................146
5.3 Structured interviews.....................................................................................146
5.3.1 Collection of structured interview data..................................................147
5.3.2 Evaluation of structured interview data.................................................148
5.3.2.1 Structured interview data coding...............................................148
5.3.2.2 Structured interview data pattern matching...............................153
5.3.3 Structured interview evaluation results summary..................................156
5.4 Participant observation 1................................................................................157
5.4.1 Collection of participant observation I data...........................................157
5.4.2 Evaluation of participant observation I data..........................................160
5.4.2.1 Participant observation I data coding........................................160
5.4.2.2 Participant observation I data pattern matching........................168
5.4.3 Participant observation I evaluation results...........................................173
5.5 Participant observation II...............................................................................175
5.5.1 Collection of participant observation II data..........................................175
5.5.2 Evaluation of participant observation II data.........................................176
5.5.2.1 Participant observation II data coding.......................................176
5.5.2.2 Participant observation II data pattern matching.......................178
5.5.3 Participant observation II evaluation results..........................................181
5.6 Triangulation of evaluation results.................................................................182
5.7 Summary and outlook...................................................................................185
6 Summary and final discussion........................................................................188
6.1 Principal findings...........................................................................................188
6.2 Limitations and areas for future research......................................................191
Bibliography.........................................................................................................194
Appendix..............................................................................................................205
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