Handbook of laboratory animal bacteriology:
Saved in:
| Main Authors: | , |
|---|---|
| Format: | Book |
| Language: | English |
| Published: |
Boca Raton [u.a.]
CRC Press
2015
|
| Edition: | 2. ed. |
| Subjects: | |
| Online Access: | Inhaltsverzeichnis Klappentext |
| Physical Description: | XVI, 280 S. Ill., graph. Darst. 23 cm |
| ISBN: | 9781482215441 |
Staff View
MARC
| LEADER | 00000nam a2200000 c 4500 | ||
|---|---|---|---|
| 001 | BV042151317 | ||
| 003 | DE-604 | ||
| 005 | 20150504 | ||
| 007 | t | ||
| 008 | 141027s2015 ad|| |||| 00||| eng d | ||
| 020 | |a 9781482215441 |9 978-1-4822-1544-1 | ||
| 035 | |a (OCoLC)904075906 | ||
| 035 | |a (DE-599)BVBBV042151317 | ||
| 040 | |a DE-604 |b ger |e rakwb | ||
| 041 | 0 | |a eng | |
| 049 | |a DE-188 |a DE-355 | ||
| 050 | 0 | |a SF996.5 | |
| 082 | 0 | |a 636.088/5 |2 21 | |
| 084 | |a WC 6300 |0 (DE-625)148126: |2 rvk | ||
| 084 | |a WF 5300 |0 (DE-625)148381: |2 rvk | ||
| 084 | |a XX 3000 |0 (DE-625)153077:12905 |2 rvk | ||
| 100 | 1 | |a Hansen, Axel Kornerup |d 1958- |e Verfasser |0 (DE-588)1070478601 |4 aut | |
| 245 | 1 | 0 | |a Handbook of laboratory animal bacteriology |c Axel Kornerup Hansen ; Dennis Sandris Nielsen |
| 250 | |a 2. ed. | ||
| 264 | 1 | |a Boca Raton [u.a.] |b CRC Press |c 2015 | |
| 300 | |a XVI, 280 S. |b Ill., graph. Darst. |c 23 cm | ||
| 336 | |b txt |2 rdacontent | ||
| 337 | |b n |2 rdamedia | ||
| 338 | |b nc |2 rdacarrier | ||
| 650 | 7 | |a handbooks |2 cabt | |
| 650 | 7 | |a laboratory animals |2 cabt | |
| 650 | 7 | |a bacteriology |2 cabt | |
| 650 | 4 | |a Animaux de laboratoire - Maladies - Diagnostic | |
| 650 | 4 | |a Animaux de laboratoire - Santé | |
| 650 | 4 | |a Bactériologie vétérinaire - Technique | |
| 650 | 4 | |a Animal Diseases |x microbiology | |
| 650 | 4 | |a Bacterial Infections |x veterinary | |
| 650 | 4 | |a Laboratory Techniques and Procedures | |
| 650 | 4 | |a Laboratory animals |x Diseases |x Diagnosis | |
| 650 | 4 | |a Laboratory animals |x Health | |
| 650 | 4 | |a Veterinary bacteriology |x Technique | |
| 650 | 0 | 7 | |a Bakteriologie |0 (DE-588)4004304-6 |2 gnd |9 rswk-swf |
| 650 | 0 | 7 | |a Versuchstiere |0 (DE-588)4078861-1 |2 gnd |9 rswk-swf |
| 689 | 0 | 0 | |a Versuchstiere |0 (DE-588)4078861-1 |D s |
| 689 | 0 | 1 | |a Bakteriologie |0 (DE-588)4004304-6 |D s |
| 689 | 0 | |5 DE-604 | |
| 700 | 1 | |a Nielsen, Dennis Sandris |d 1977- |e Verfasser |0 (DE-588)1070481173 |4 aut | |
| 856 | 4 | 2 | |m Digitalisierung UB Regensburg - ADAM Catalogue Enrichment |q application/pdf |u http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=027591154&sequence=000003&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |3 Inhaltsverzeichnis |
| 856 | 4 | 2 | |m Digitalisierung UB Regensburg - ADAM Catalogue Enrichment |q application/pdf |u http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=027591154&sequence=000004&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA |3 Klappentext |
| 999 | |a oai:aleph.bib-bvb.de:BVB01-027591154 | ||
Record in the Search Index
| _version_ | 1804152643176628224 |
|---|---|
| adam_text | Contents
Preface
..............................................................................................................xiii
About the Authors
...........................................................................................xv
Chapter
1
Laboratory animal bacteriology: The past, the
present, and the future
..............................................................1
1.1
Foundation of the discipline of bacteriology
.......................................1
1.2
The need for securing the absence of zoonoses
..................................2
1.3
Eradication of bacterial pathogens
........................................................2
1.3.1
The early age of laboratory animal pathology
......................2
1.3.2
Specific pathogen-free animal breeding and health
monitoring
..................................................................................3
1.3.3
New agents with a research-interfering potential
................4
1.3.4
The development of health monitoring
..................................4
1.4
The impact of the symbiotic microbiota
...............................................5
1.4.1
The development of gnotobiotechnology
..............................5
1.4.2
Schaedler s flora
.........................................................................6
1.4.3
Microbiome studies
...................................................................7
1.5
The future of laboratory animal bacteriology
.....................................8
References
.........................................................................................................10
Chapter
2
Sampling animals for bacteriological examination
..........15
2.1
Examining healthy animals
.................................................................15
2.1.1
Sampling strategies
.................................................................17
2.1.1.1
Random sampling
...................................................17
2.1.1.2
Calculation of the sample size
..............................17
2.1.2
Sampling frequency
................................................................19
2.1.3
Defining the microbiological entity
......................................19
2.2
Characterization of the commensal microbiota
................................20
2.3
Sampling procedures
............................................................................21
2.3.1
Planning the work
................................................................... 21
2.3.2
Euthanasia
................................................................................21
2.3.3
Blood sampling
........................................................................24
2.3.4
Instruments and sterilizing procedures during sampling...
26
v
ΌΊ
Contents
2.3.5
Opening and inspecting the carcass
....................................27
2.3.6
Sampling from various organs
..............................................27
2.3.7
Sampling from diseased animals
..........................................34
2.3.8
Sampling from live animals
...................................................36
2.3.8.1
Sampling from the gut
...........................................36
2.3.8.2
Sampling from the respiratory pathways
...........39
References
.........................................................................................................45
Chapter
3
Cultivation and identification of bacteria
............................49
3.1
The basic steps in cultivation
...............................................................49
3.2
The choice of media
...............................................................................50
3.3
Incubation of media
..............................................................................51
3.4
Isolation of bacteria
...............................................................................52
3.5
Initial characterization of the isolates
.................................................52
3.6
Conclusive identification
......................................................................55
3.6.1
Specific techniques used for identification of bacteria
.......59
3.6.1.1
Gram-stainability tests
...........................................59
3.6.1.2
Other methods used for describing the
shape of bacteria
......................................................61
3.6.1.3
Motility tests
............................................................61
3.6.1.4
Test for aerobic and anaerobic growth
................62
3.6.1.5
Catalase test
.............................................................62
3.6.1.6
Cytochrome
oxidase
test
........................................62
3.6.1.7
Acid-fast or spore staining
....................................63
3.6.1.8
Carbohydrate fermentation and utilization
assays
........................................................................63
3.6.1.9
Disk methods
...........................................................64
3.6.1.10
Commercial test kits
...............................................64
3.7
Molecular biology-based methods for rapid identification of
microorganisms
.....................................................................................67
3.7.1
Extraction of
DNA...................................................................67
3.7.2
Grouping by repetitive
DNA
element PCR
.........................67
3.7.3
Identification by ribosomal
RNA gene
sequencing
............68
References
.........................................................................................................69
Chapter
4
Immunological methods
.........................................................71
4.1
Antigens and antibodies
.......................................................................71
4.2
Agglutination
.........................................................................................72
4.3
immunofluorescence techniques
.........................................................73
4.3.1
Diagnosing the presence of bacteria in a sample
................73
4.3.2
The immunofluorescence assay
.............................................75
4.4
Immunoenzymatic staining
.................................................................77
4.5
Enzvme-linked immunosorbent assav
..............................................79
Contents
vii
4.5.1
Principles
..................................................................................79
4.5.2
The microtiter plates
...............................................................79
4.5.3
The antigen
...............................................................................82
4.5.4
Antibodies, enzymes, and substrates
...................................82
4.5.5
Coating the wells
.....................................................................84
4.5.6
Blocking the wells
....................................................................85
4.5.7
Performing the assay
...............................................................86
4.5.8
Control sera
..............................................................................87
4.5.9
Interpretation of the
OD
value
...............................................87
4.6
Immunoblotting
.....................................................................................87
4.7
Multiplex
.................................................................................................89
References
.........................................................................................................90
Chapter
5
Molecular biology-based methods for microbiota
characterization
.........................................................................91
5.1
Why molecular biology-based methods?
...........................................91
5.2
RNA
and
DNA
storage and extraction
...............................................92
5.3
Denaturing and temperature gradient gel electrophoresis
.............92
5.4
Terminal restriction fragment length polymorphism analysis
......95
5.5
Clone library analysis
...........................................................................95
5.6
High-throughput sequencing
..............................................................97
5.7
Quantitative real-time PCR
..................................................................99
References
.......................................................................................................100
Chapter
6
Mechanisms behind bacterial impact on animal
models
.......................................................................................103
6.1
Mechanisms of pathogenicity and research interference from
specific bacteria
....................................................................................103
6.1.1
Pathogenicity versus research interference
.......................103
6.1.2
Epidemiological terms
..........................................................104
6.1.3
Host-bacterial interaction influencing pathogenicity
and research interference
.....................................................104
6.1.3.1
Adhesins and receptors
.......................................106
6.1.3.2
Toxins
......................................................................108
6.1.4
Host-environment interaction influencing
pathogenicity and research interference
............................109
6.2
Mechanisms of pathogenicity and research interference from
the commensal gut microbiota
...........................................................110
6.2Л
Host-microbial interactions within immunity
..................110
6.2.1.1
Interactions within acquired immunity
.............110
6.2.1.2
Interactions within innate immunity
.................113
6.2.2
Host-microbial interactions within metabolism
...............115
References
........................................................................................................116
viti
Contents
Chapter
7
Systematic classification of bacteria
...................................127
7.1
Domains of life
.....................................................................................127
7.1.1
Operational
taxonomic
units
...............................................127
7.1.2
Members of the mice and rat microbiome
.........................128
References
.......................................................................................................131
Chapter
8
Firmicutes
.................................................................................133
8.1
Introduction
..........................................................................................134
8.2
Streptococcaceae
..................................................................................134
8.2.1
Impact on the host
.................................................................136
8.2.1.1
Lanceŕiekťs
groups A, B, C, and
G
.....................136
8.2.1.2
Streptococcus pneumoniae
.......................................136
8.2.1.3
Lancefield s group
D
.............................................137
8.2.1.4
Lactococcus spp
.......................................................137
8.2.1.5
Gemella
....................................................................137
8.2.2
Characteristics of the agent
..................................................137
8.3
Enterococcaceae
...................................................................................139
8.4
Aerococcaceae
......................................................................................140
8.5
Lactobacillaceae
...................................................................................140
8.6
Leuconostaceae
.....................................................................................141
8.7
Staphylococcaceae
.................................................................................141
8.7.1
Impact on the host
..................................................................141
8.7.2
Characteristics of the agent
...................................................141
8.8
ВасШасеае
.............................................................................................144
8.8.1
Impact on the host
.................................................................144
8.8.2
Characteristics of the agent
..................................................144
8.9
Listeriaceae
...........................................................................................146
8.9.1
Impact on the host
.................................................................146
8.9.2
Characteristics of the agent
..................................................146
8.10
Erysipelotrichidae
................................................................................147
8.11
Clostridiaceae
.......................................................................................149
8.11.1
Impact on the host
.................................................................149
8.11.1.1
Clostridium difficile and
C. per/ringens
.................150
8.11.1.2
Clostridium
spiro/orme
............................................150
8.11.1.3
Clostridium
pili/orme
...............................................150
8.11.1.4
Segmented filamentous bacteria (Candidatus
savagella)
..................................................................151
8.11.1.5
Vaecalibacterium prausnitzii
....................................152
8.11.2
Characteristics of the agent
..................................................153
8.11.2.1
Clostridium difficile and C. perfringens
.................153
8.11.2.2
Clostridmm spiroforme
............................................156
8.11.2.3
Clostridium piliforme
...............................................156
8Л1.2.4
Segmented filamentous bacteria {Candidatus
savagella)
..................................................................157
Contents ix
8.12 Lachnospiraceae...................................................................................158
8.13 Eubacteriaceae......................................................................................158
8.14 Ruminococcaceae.................................................................................158
References
.......................................................................................................158
Chapter
9 Bacteroidetes............................................................................167
9.1
Introduction
...........................................................................................167
9.2
Bacteroicïales
.........................................................................................168
9.2.1
Bacteroidaceae
........................................................................168
9.2.1.1
Impact on the host
................................................168
9.2.1.2
Characteristics of the agent
.................................169
9.2.2
S24-7
.........................................................................................169
9.2.3
Prevotellaceae
.........................................................................169
9.2.3.1
Impact on the host
................................................169
9.2.3.2
Characteristics of the agent
.................................170
9.2.4
Rikenellaceae
..........................................................................170
9.2.5
Porphyromonadaceae
............................................................170
9.3
Flavobacteriales
....................................................................................170
9.4
Sphingobacteriales
...............................................................................171
9.4.1
Cilia-associated respiratory bacillus
...................................171
9.4.1.1
Impact on the host
................................................171
9.4.1.2
Characteristics of the agent
.................................172
References
.......................................................................................................172
Chapter
10
Proteobacteria
..........................................................................177
10.1
Gammaproteobacteria
........................................................................177
10.1.1
Enterobacteriaceae
.................................................................177
10.1.1.1
Impact on the host
................................................178
10.1.1.2
Characteristics of the agent
.................................180
10.1.2
Pasteurellaceae
.......................................................................186
10.1.2.1
Impact on the host
................................................186
10.1.2.2
Characteristics of the agent
.................................188
10.13
Pseudomonadacea
.................................................................191
10.13.1
Pseudomonas
.........................................................191
10.1.4
Francisellaceae
.......................................................................192
10.1 AI Francisella..............................................................192
10.1.5
Aeromonadaceae, Xanthomonadaceae,
Sphingomonadaceae, and Moraxcellaceae
.........................194
10.2
Betaproteobacteria
...............................................................................195
10.2Л
Alcaligenaceae
...............................-........................................195
10.2.1.1
Bordeteila
...............................................................195
10.2.2
Spirillaceae..
............................................................................196
10.2.2.1
Spirillum minus
.......................................................196
χ
Contents
10.3
Epsiłonproteobacteria
.........................................................................197
10.3.1
Campyłobacteraceae
..............................................................197
10.3.1.1
Campylobacter
......................................................197
10.3.2
Helicobacteraceae
..................................................................199
10.3.2.1
Helicobacter
...........................................................199
10.3.2.2
Rabbit-associated cilia-associated
respiratory
bacillus...............................................
203
10.4
Alphaproteobacteria
............................................................................203
References.......................................................................................................
204
Chapter
11
Actinobacteria
..........................................................................213
11.1
Introduction
..........................................................................................213
11.2
Micrococcaceae
....................................................................................213
11.3
Corynebacteriaceae
..............................................................................214
11.3.1
Characteristics of infection
...................................................215
11.3.2
Characteristics of the agent
...................................................216
11.4
Actinomycetaceae
.................................................................................216
11.4.1
Actinomyces
..............................................................................216
11.4.2
Arcanobacterium
......................................................................218
11.5
Mycobacteriaceae
.................................................................................219
11.5.1
Characteristics of infection
...................................................219
11.5.2
Characteristics of the agent
..................................................219
11.6
Bifidobacteriaceae
................................................................................222
References
.......................................................................................................223
Chapter
12
Spirochaetae
.............................................................................227
12.1
Introduction
..........................................................................................227
12.2
Treponema
..............................................................................................227
12.2.1
Impact on the host
.................................................................227
12.2.2
Characteristics of the agent
..................................................228
12.3
Bmchyspira
.............................................................................................229
12.4
Leptospira
...............................................................................................229
12.4.1
Impact on the host
.................................................................229
12.4.2
Characteristics of the agent
..................................................230
References
.......................................................................................................231
Chapter
13
Tenericutes
...............................................................................233
13.1
Introduction
..........................................................................................233
13.2
Mi/copksma
............................................................................................233
13.2.1
Impact on the host
.................................................................233
13.2.2
Characteristics of the agent
..................................................235
13.3
Acholeplasma
..........................................................................................238
References
.......................................................................................................239
Contents xi
Chapter
14
Verrucomicrobia, Deferribacteres, Fusobacterium,
andTM7
....................................................................................243
14.1
Verrucomicrobia
..................................................................................243
14.1
Л
Akkermansia
.............................................................................243
14.1.1.1
Impact on the host
................................................243
14.1.1.2
Characteristics of the agent
.................................244
14.2
Deferribacteres
.....................................................................................244
14.2.1
Mucispirillum schaedleri
..........................................................244
14.2.1.1
Impact on the host
................................................244
14.2.1.2
Characteristics of the agent
.................................245
14.3
Fusobacteria
..........................................................................................245
14.3.1
Fusobacterium necrophorum
....................................................245
14.3.1.1
Impact on the host
................................................245
14.3.1.2
Characteristics of the agent
.................................246
14.3.2
Streptobacillus moniliformis
.....................................................247
14.3.2.1
Impact on the host
................................................247
14.3.2.2
Characteristics of the agent
.................................248
14.4
Candidate phylum TM7
......................................................................248
References
.......................................................................................................249
Appendix A: Producers of reagents for laboratory animal
bacteriology
.....................................................................................................253
Appendix B: Biosafety levels for microbiological laboratories
................255
References
.......................................................................................................260
Appendix C: Media buffers and reagents commonly applied in
laboratory animal bacteriology
....................................................................261
Index
................................................................................................................273
The Handbook of Laboratory Animal Bacteriology, Second Edition
provides comprehensive information on all bacterial phylae found in
laboratory rodents and rabbits to assist managers, veterinary patholo-
gists, and laboratory animal veterinarians in the management of these
organisms. The book starts by examining the general aspects of bacteri¬
ology and how to sample and identify bacteria in animals. It then
describes the most relevant species within each phylum and discusses
the impact they may have on research. Emphasizing those bacteria
known to interfere with research protocols, the book offers methods for
isolation and differentiation among related bacteria. It discusses where
to purchase reagents for rodent bacteriology and outlines standards for
safety in a bacteriological laboratory.
Highlights of the second edition:
•
Focuses on modern sequencing techniques based on molecular
identification
•
Reorganizes content according to modern systematics based
on new identification methods
•
Presents new chapters on mechanisms behind bacterial impact on
animal models and on the systematic classification of bacteria
•
Provides information on a range of bacteria interfering with animal
models for human disease, not only for those bacteria which cause
disease in laboratory animal colonies
•
Includes new figures in color and with enhanced resolution
The book is essential reading for those interested in the management
of organisms known to interfere with the colony health of rabbits and
rodents used in research protocols—including facility managers, clinical
veterinarians, veterinary pathologists, and researchers.
|
| any_adam_object | 1 |
| author | Hansen, Axel Kornerup 1958- Nielsen, Dennis Sandris 1977- |
| author_GND | (DE-588)1070478601 (DE-588)1070481173 |
| author_facet | Hansen, Axel Kornerup 1958- Nielsen, Dennis Sandris 1977- |
| author_role | aut aut |
| author_sort | Hansen, Axel Kornerup 1958- |
| author_variant | a k h ak akh d s n ds dsn |
| building | Verbundindex |
| bvnumber | BV042151317 |
| callnumber-first | S - Agriculture |
| callnumber-label | SF996 |
| callnumber-raw | SF996.5 |
| callnumber-search | SF996.5 |
| callnumber-sort | SF 3996.5 |
| callnumber-subject | SF - Animal Culture |
| classification_rvk | WC 6300 WF 5300 XX 3000 |
| ctrlnum | (OCoLC)904075906 (DE-599)BVBBV042151317 |
| dewey-full | 636.088/5 |
| dewey-hundreds | 600 - Technology (Applied sciences) |
| dewey-ones | 636 - Animal husbandry |
| dewey-raw | 636.088/5 |
| dewey-search | 636.088/5 |
| dewey-sort | 3636.088 15 |
| dewey-tens | 630 - Agriculture and related technologies |
| discipline | Biologie Agrar-/Forst-/Ernährungs-/Haushaltswissenschaft / Gartenbau Medizin |
| edition | 2. ed. |
| format | Book |
| fullrecord | <?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>02503nam a2200565 c 4500</leader><controlfield tag="001">BV042151317</controlfield><controlfield tag="003">DE-604</controlfield><controlfield tag="005">20150504 </controlfield><controlfield tag="007">t</controlfield><controlfield tag="008">141027s2015 ad|| |||| 00||| eng d</controlfield><datafield tag="020" ind1=" " ind2=" "><subfield code="a">9781482215441</subfield><subfield code="9">978-1-4822-1544-1</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(OCoLC)904075906</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-599)BVBBV042151317</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-604</subfield><subfield code="b">ger</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1="0" ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="049" ind1=" " ind2=" "><subfield code="a">DE-188</subfield><subfield code="a">DE-355</subfield></datafield><datafield tag="050" ind1=" " ind2="0"><subfield code="a">SF996.5</subfield></datafield><datafield tag="082" ind1="0" ind2=" "><subfield code="a">636.088/5</subfield><subfield code="2">21</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">WC 6300</subfield><subfield code="0">(DE-625)148126:</subfield><subfield code="2">rvk</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">WF 5300</subfield><subfield code="0">(DE-625)148381:</subfield><subfield code="2">rvk</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">XX 3000</subfield><subfield code="0">(DE-625)153077:12905</subfield><subfield code="2">rvk</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Hansen, Axel Kornerup</subfield><subfield code="d">1958-</subfield><subfield code="e">Verfasser</subfield><subfield code="0">(DE-588)1070478601</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Handbook of laboratory animal bacteriology</subfield><subfield code="c">Axel Kornerup Hansen ; Dennis Sandris Nielsen</subfield></datafield><datafield tag="250" ind1=" " ind2=" "><subfield code="a">2. ed.</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="a">Boca Raton [u.a.]</subfield><subfield code="b">CRC Press</subfield><subfield code="c">2015</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">XVI, 280 S.</subfield><subfield code="b">Ill., graph. Darst.</subfield><subfield code="c">23 cm</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="b">n</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="b">nc</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">handbooks</subfield><subfield code="2">cabt</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">laboratory animals</subfield><subfield code="2">cabt</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">bacteriology</subfield><subfield code="2">cabt</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Animaux de laboratoire - Maladies - Diagnostic</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Animaux de laboratoire - Santé</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Bactériologie vétérinaire - Technique</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Animal Diseases</subfield><subfield code="x">microbiology</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Bacterial Infections</subfield><subfield code="x">veterinary</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Laboratory Techniques and Procedures</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Laboratory animals</subfield><subfield code="x">Diseases</subfield><subfield code="x">Diagnosis</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Laboratory animals</subfield><subfield code="x">Health</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Veterinary bacteriology</subfield><subfield code="x">Technique</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Bakteriologie</subfield><subfield code="0">(DE-588)4004304-6</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Versuchstiere</subfield><subfield code="0">(DE-588)4078861-1</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="689" ind1="0" ind2="0"><subfield code="a">Versuchstiere</subfield><subfield code="0">(DE-588)4078861-1</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="0" ind2="1"><subfield code="a">Bakteriologie</subfield><subfield code="0">(DE-588)4004304-6</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="0" ind2=" "><subfield code="5">DE-604</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Nielsen, Dennis Sandris</subfield><subfield code="d">1977-</subfield><subfield code="e">Verfasser</subfield><subfield code="0">(DE-588)1070481173</subfield><subfield code="4">aut</subfield></datafield><datafield tag="856" ind1="4" ind2="2"><subfield code="m">Digitalisierung UB Regensburg - ADAM Catalogue Enrichment</subfield><subfield code="q">application/pdf</subfield><subfield code="u">http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=027591154&sequence=000003&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA</subfield><subfield code="3">Inhaltsverzeichnis</subfield></datafield><datafield tag="856" ind1="4" ind2="2"><subfield code="m">Digitalisierung UB Regensburg - ADAM Catalogue Enrichment</subfield><subfield code="q">application/pdf</subfield><subfield code="u">http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=027591154&sequence=000004&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA</subfield><subfield code="3">Klappentext</subfield></datafield><datafield tag="999" ind1=" " ind2=" "><subfield code="a">oai:aleph.bib-bvb.de:BVB01-027591154</subfield></datafield></record></collection> |
| id | DE-604.BV042151317 |
| illustrated | Illustrated |
| indexdate | 2024-07-10T01:13:58Z |
| institution | BVB |
| isbn | 9781482215441 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-027591154 |
| oclc_num | 904075906 |
| open_access_boolean | |
| owner | DE-188 DE-355 DE-BY-UBR |
| owner_facet | DE-188 DE-355 DE-BY-UBR |
| physical | XVI, 280 S. Ill., graph. Darst. 23 cm |
| publishDate | 2015 |
| publishDateSearch | 2015 |
| publishDateSort | 2015 |
| publisher | CRC Press |
| record_format | marc |
| spelling | Hansen, Axel Kornerup 1958- Verfasser (DE-588)1070478601 aut Handbook of laboratory animal bacteriology Axel Kornerup Hansen ; Dennis Sandris Nielsen 2. ed. Boca Raton [u.a.] CRC Press 2015 XVI, 280 S. Ill., graph. Darst. 23 cm txt rdacontent n rdamedia nc rdacarrier handbooks cabt laboratory animals cabt bacteriology cabt Animaux de laboratoire - Maladies - Diagnostic Animaux de laboratoire - Santé Bactériologie vétérinaire - Technique Animal Diseases microbiology Bacterial Infections veterinary Laboratory Techniques and Procedures Laboratory animals Diseases Diagnosis Laboratory animals Health Veterinary bacteriology Technique Bakteriologie (DE-588)4004304-6 gnd rswk-swf Versuchstiere (DE-588)4078861-1 gnd rswk-swf Versuchstiere (DE-588)4078861-1 s Bakteriologie (DE-588)4004304-6 s DE-604 Nielsen, Dennis Sandris 1977- Verfasser (DE-588)1070481173 aut Digitalisierung UB Regensburg - ADAM Catalogue Enrichment application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=027591154&sequence=000003&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis Digitalisierung UB Regensburg - ADAM Catalogue Enrichment application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=027591154&sequence=000004&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA Klappentext |
| spellingShingle | Hansen, Axel Kornerup 1958- Nielsen, Dennis Sandris 1977- Handbook of laboratory animal bacteriology handbooks cabt laboratory animals cabt bacteriology cabt Animaux de laboratoire - Maladies - Diagnostic Animaux de laboratoire - Santé Bactériologie vétérinaire - Technique Animal Diseases microbiology Bacterial Infections veterinary Laboratory Techniques and Procedures Laboratory animals Diseases Diagnosis Laboratory animals Health Veterinary bacteriology Technique Bakteriologie (DE-588)4004304-6 gnd Versuchstiere (DE-588)4078861-1 gnd |
| subject_GND | (DE-588)4004304-6 (DE-588)4078861-1 |
| title | Handbook of laboratory animal bacteriology |
| title_auth | Handbook of laboratory animal bacteriology |
| title_exact_search | Handbook of laboratory animal bacteriology |
| title_full | Handbook of laboratory animal bacteriology Axel Kornerup Hansen ; Dennis Sandris Nielsen |
| title_fullStr | Handbook of laboratory animal bacteriology Axel Kornerup Hansen ; Dennis Sandris Nielsen |
| title_full_unstemmed | Handbook of laboratory animal bacteriology Axel Kornerup Hansen ; Dennis Sandris Nielsen |
| title_short | Handbook of laboratory animal bacteriology |
| title_sort | handbook of laboratory animal bacteriology |
| topic | handbooks cabt laboratory animals cabt bacteriology cabt Animaux de laboratoire - Maladies - Diagnostic Animaux de laboratoire - Santé Bactériologie vétérinaire - Technique Animal Diseases microbiology Bacterial Infections veterinary Laboratory Techniques and Procedures Laboratory animals Diseases Diagnosis Laboratory animals Health Veterinary bacteriology Technique Bakteriologie (DE-588)4004304-6 gnd Versuchstiere (DE-588)4078861-1 gnd |
| topic_facet | handbooks laboratory animals bacteriology Animaux de laboratoire - Maladies - Diagnostic Animaux de laboratoire - Santé Bactériologie vétérinaire - Technique Animal Diseases microbiology Bacterial Infections veterinary Laboratory Techniques and Procedures Laboratory animals Diseases Diagnosis Laboratory animals Health Veterinary bacteriology Technique Bakteriologie Versuchstiere |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=027591154&sequence=000003&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=027591154&sequence=000004&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA |
| work_keys_str_mv | AT hansenaxelkornerup handbookoflaboratoryanimalbacteriology AT nielsendennissandris handbookoflaboratoryanimalbacteriology |