Transcriptional Control of Lineage Differentiation in Immune Cells:
Insights into the regulation of immune cell lineage differentiation and specification as well as into the control of lineage integrity, stability and plasticity are of fundamental importance to understanding innate and adaptive immune responses. In this volume, leading experts provide an up-to-date...
Saved in:
| Format: | Electronic eBook |
|---|---|
| Language: | English |
| Published: |
Cham [u.a.]
Springer
2014
|
| Series: | Current Topics in Microbiology and Immunology
381 |
| Subjects: | |
| Online Access: | TUM01 UBT01 Volltext |
| Summary: | Insights into the regulation of immune cell lineage differentiation and specification as well as into the control of lineage integrity, stability and plasticity are of fundamental importance to understanding innate and adaptive immune responses. In this volume, leading experts provide an up-to-date and comprehensive overview of recent advances in the transcriptional control mechanisms and transcription factor networks that regulate these processes in a variety of different immune cell lineages. The chapters cover the regulation of T versus B cell lineage choice, discuss early B cell development and pre-B cell leukemia prevention, address transcriptional control mechanisms during Th differentiation, in regulatory T cells and iNKT cells, detail genomic switches in helper cell fate choice and plasticity, and highlight the role of the BTB-zinc finger family of transcription factors in T cells. Moreover, the chapters discuss transcriptional networks in DCs, NK cells and in innate lymphoid cells. Together, the reviews illustrate key transcriptional control mechanisms that regulate the development and function of immune cells and demonstrate the impressive advances made over the last decade |
| Physical Description: | 1 Online-Ressource |
| ISBN: | 9783319073958 |
| DOI: | 10.1007/978-3-319-07395-8 |
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| isbn | 9783319073958 |
| language | English |
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| series | Current Topics in Microbiology and Immunology |
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| spelling | Transcriptional Control of Lineage Differentiation in Immune Cells Wilfried Ellmeier ; Ichiro Taniuchi, ed. Cham [u.a.] Springer 2014 1 Online-Ressource txt rdacontent c rdamedia cr rdacarrier Current Topics in Microbiology and Immunology 381 Insights into the regulation of immune cell lineage differentiation and specification as well as into the control of lineage integrity, stability and plasticity are of fundamental importance to understanding innate and adaptive immune responses. In this volume, leading experts provide an up-to-date and comprehensive overview of recent advances in the transcriptional control mechanisms and transcription factor networks that regulate these processes in a variety of different immune cell lineages. The chapters cover the regulation of T versus B cell lineage choice, discuss early B cell development and pre-B cell leukemia prevention, address transcriptional control mechanisms during Th differentiation, in regulatory T cells and iNKT cells, detail genomic switches in helper cell fate choice and plasticity, and highlight the role of the BTB-zinc finger family of transcription factors in T cells. Moreover, the chapters discuss transcriptional networks in DCs, NK cells and in innate lymphoid cells. Together, the reviews illustrate key transcriptional control mechanisms that regulate the development and function of immune cells and demonstrate the impressive advances made over the last decade Medizin Medicine Immunology Immunologie (DE-588)4026637-0 gnd rswk-swf Immunologie (DE-588)4026637-0 s 1\p DE-604 Ellmeier, Wilfried 1966- Sonstige (DE-588)1059261162 oth Taniuchi, Ichiro Sonstige oth Erscheint auch als Druckausgabe 978-3-319-07394-1 Current Topics in Microbiology and Immunology 381 (DE-604)BV022782309 381 https://doi.org/10.1007/978-3-319-07395-8 Verlag Volltext 1\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk |
| spellingShingle | Transcriptional Control of Lineage Differentiation in Immune Cells Current Topics in Microbiology and Immunology Medizin Medicine Immunology Immunologie (DE-588)4026637-0 gnd |
| subject_GND | (DE-588)4026637-0 |
| title | Transcriptional Control of Lineage Differentiation in Immune Cells |
| title_auth | Transcriptional Control of Lineage Differentiation in Immune Cells |
| title_exact_search | Transcriptional Control of Lineage Differentiation in Immune Cells |
| title_full | Transcriptional Control of Lineage Differentiation in Immune Cells Wilfried Ellmeier ; Ichiro Taniuchi, ed. |
| title_fullStr | Transcriptional Control of Lineage Differentiation in Immune Cells Wilfried Ellmeier ; Ichiro Taniuchi, ed. |
| title_full_unstemmed | Transcriptional Control of Lineage Differentiation in Immune Cells Wilfried Ellmeier ; Ichiro Taniuchi, ed. |
| title_short | Transcriptional Control of Lineage Differentiation in Immune Cells |
| title_sort | transcriptional control of lineage differentiation in immune cells |
| topic | Medizin Medicine Immunology Immunologie (DE-588)4026637-0 gnd |
| topic_facet | Medizin Medicine Immunology Immunologie |
| url | https://doi.org/10.1007/978-3-319-07395-8 |
| volume_link | (DE-604)BV022782309 |
| work_keys_str_mv | AT ellmeierwilfried transcriptionalcontroloflineagedifferentiationinimmunecells AT taniuchiichiro transcriptionalcontroloflineagedifferentiationinimmunecells |