Regulated cell death: B Necroptotic, autophagic and other non-apoptotic mechanisms
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
Amsterdam [u.a.]
Elsevier, Acad. Press
2014
|
| Ausgabe: | 1. ed. |
| Schriftenreihe: | Methods in enzymology
545 |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | XIII, 337 S., [13] Bl. Ill., graph. Darst. |
| ISBN: | 9780128014301 |
Internformat
MARC
| LEADER | 00000nam a2200000 cc4500 | ||
|---|---|---|---|
| 001 | BV042067338 | ||
| 003 | DE-604 | ||
| 005 | 00000000000000.0 | ||
| 007 | t | ||
| 008 | 140910s2014 ad|| |||| 00||| eng d | ||
| 020 | |a 9780128014301 |9 978-0-12-801430-1 | ||
| 035 | |a (OCoLC)891513162 | ||
| 035 | |a (DE-599)BVBBV042067338 | ||
| 040 | |a DE-604 |b ger |e rakwb | ||
| 041 | 0 | |a eng | |
| 049 | |a DE-355 |a DE-19 | ||
| 245 | 1 | 0 | |a Regulated cell death |n B |p Necroptotic, autophagic and other non-apoptotic mechanisms |c ed. by Avi Ashkenazi ... |
| 250 | |a 1. ed. | ||
| 264 | 1 | |a Amsterdam [u.a.] |b Elsevier, Acad. Press |c 2014 | |
| 300 | |a XIII, 337 S., [13] Bl. |b Ill., graph. Darst. | ||
| 336 | |b txt |2 rdacontent | ||
| 337 | |b n |2 rdamedia | ||
| 338 | |b nc |2 rdacarrier | ||
| 490 | 1 | |a Methods in enzymology |v 545 | |
| 490 | 0 | |a Methods in enzymology |v ... | |
| 700 | 1 | |a Ashkenazi, Avi |e Sonstige |4 oth | |
| 773 | 0 | 8 | |w (DE-604)BV042034231 |g 2 |
| 830 | 0 | |a Methods in enzymology |v 545 |w (DE-604)BV000000938 |9 545 | |
| 856 | 4 | 2 | |m Digitalisierung UB Regensburg - ADAM Catalogue Enrichment |q application/pdf |u http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=027508087&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |3 Inhaltsverzeichnis |
| 999 | |a oai:aleph.bib-bvb.de:BVB01-027508087 | ||
Datensatz im Suchindex
| _version_ | 1804152509621600256 |
|---|---|
| adam_text | CONTENTS
Contributors
¡χ
Preface
xiii
1.
Assays for Necroptosis and Activity of RIP Kinases
1
Alexei Degterev, Wen Zhou, Jenny L.
Maki,
and Junying Yuan
1.
Introduction
2
2.
Cellular Models of Necroptosis
5
3.
Measurement of Necroptotic Cell Death
9
4.
Recapitulation of RIP! Kinase Expression in RIPl-Deficient Jurkat Cells
16
5.
Analysis of
Necrosome
Complex Formation
18
6.
Endogenous RIPK Autopbospborylation Assays
21
7.
Analysis of
Recombinant RIPK1
Kinase Activity and Inhibition
by Necrostatins
23
8.
Conclusions
28
Acknowledgments
29
References
29
2.
IAP Family of Cell Death and Signaling Regulators
35
John
Silke
and
Domagoj Vucic
1.
Identification of lAPs, Structure, and Domain Function
36
2.
IAP Proteins and Ceil Death Pathways
39
References
55
3.
Activation of the NLRP3 Inflammasome by Proteins
That Signal for Necroptosis
67
Tae-Bong Kang,
Seung
Hoon Yang,
Beata Toth,
Andrew Kovalenko,
and David
Wallach
1.
Introduction
68
2.
Altered Expression or Function of Enzymes That Control Induction
of Necroptosis Results in Altered Generation of
IL
1
β
and IL-18
by Mouse DCs
69
3.
Signaling Proteins Controlling Necroptosis Affect Assembly
of the NLRP3 Inflammasome
72
vi
Contents
4.
Does the Similarity Between the Regulation of Nocroptosis and of
Assembly of the NLRP3
Infla
m
ma some Reflect Activation of the
nflammasome by Products of Necrotic Cells7
75
5.
Concluding Remarks
78
Acknowledgments
/9
References
79
4.
Characterization of the Ripoptosome and Its Components:
Implications for Anti-inflammatory and Cancer Therapy
83
Ramon Schilling, Peter Geserick, and Martin Leverkus
1.
Introduction
84
2.
The Ripoptosome: Cellular Model Systems to Study Its Formation
87
3.
Biochemical Analysis of the Ripoptosome: Analysis of Ripoptosome
Formation and Identification of Novel Components via immunoprecipitation
and Mass Specirometry
94
4.
Outlook: Future ImolicatOns of the Function and Regulation
o f t
hi
e R i p o
pto s
ο
m e
9 7
References
100
5.
Tools and Techniques to Study Ligand-Receptor
Interactions and Receptor Activation by TNF
Superfamily Members
103
Pascal Schneider,
Laure
Willen,
and
Cristian
R. Smulski
1.
Introduction
104
2.
Methods
106
3.
Conclusions
123
Acknowledgments
124
References
124
6.
Necrotic Cell Death in Caenorhabditis
elegans
127
Vassiliki Nikoletopoulou and Nektarios Tavernarakis
1.
Introduction
128
2.
Necrotic Cell Death Paradigms During
C elegans
Development
130
3.
Nondevelopmental Necrotic Death
134
4.
Execution of Necrosis
140
5.
C. elegans
as a Model for Human Diseases Entailing Necrosis
142
6.
Concluding Remarks
147
Acknowledgments
149
References
149
Contents
vii
7.
Noncanonical Cell Death in the Nematode Caenorhabditis
elegans
157
Maxime
J.
Kinet and Shai Shaham
1.
Introduction
158
2.
Pathological
Ce .
Death Induced by Genome Lesions and
Environmental Stress
159
3.
Developmental Cell Deaths That Do not Follow the Canonical
Apoptotic Pathway
168
4.
Nonapoptotic, Caspase-lndependent Linker Cell Death
172
5.
Conclusion
175
Acknowledgments
175
References
175
8.
Autophagy and Cell Death in the Fly
181
Charles Nelson and Eric H. Baehrecke
1.
traduction
182
2.
Matenals a d
Methods
184
3.
Data Analyss and Interpretation
191
Acxnowlecgments
198
References
198
9.
Structural Studies of Death Receptors
201
Paul
С
Driscoll
1.
Introduction Signaling by the Tumor Necrosis Receptor Superfamily
202
2.
Outline Death Ligand and
DR
Domain Structure
204
3.
DR Ectodomain
Structure
206
4.
Physiological Complexes of Death Ligands with DRs
213
5.
A Decoy Receptor-Ligand Complex
214
6.
The
DR Preligand
Association Domain
215
7.
Death Ligand Structure-Activity Relationships
217
8.
Structural Analysis of AntiTNF Agents
219
9.
Structural Analysis of the Blockade of
DR
Function
220
10.
DR Cytoplasmic
Domains
221
1 1.
DD Structure
222
12.
The DD Superfamily
225
13.
DD Assembly Revealed by the Structure of the PIDDosome Core
226
14.
Structural Characterization of
CD9b:FADD-DD
Complexes
228
15.
Relevance of CD95TADD-DD Assemblies to Physiological CD95 Signaling
230
16.
Unanswered Questions and Future Prospects
233
Acknowledgments
234
References
234
viii
Contents
10.
Use of
E2^Ubiquitin
Conjugates for the Characterization of
Ubiquitin Transfer by RING E3
Ligases
Such as the Inhibitor
of Apoptosis Proteins
243
Adam J. Middleton, Rhesa Budhidarmo, and Catherine L. Day
1.
Introduction
244
2.
Synthesis of E2~Ub Conjugates
246
3.
Characterization of RING-E2~Ub Complexes
25
4.
Conclusion
259
Acknowledgments
/60
References
260
11.
Multidimensional Profiling in the Investigation of
Small Molecule Induced Cell Death
265
Adam J. Wolpaw and Brent R.
Stockwell
1.
introduci
on
2.
Gene Expression Profiling
3.
Protein Quantification
4.
Gene—Small
Molecu :e
interactions
5.
Small-Molecule Combination Interactions
6.
Ce!
Line Viability Profiling
7.
Quantitative Imaging
8.
Modulatory
Profiling
9.
Conclusions
References
Author
Index
Subject
Index
266
771
2/7
280
782
284
288
290
796
297
303
331
|
| any_adam_object | 1 |
| building | Verbundindex |
| bvnumber | BV042067338 |
| ctrlnum | (OCoLC)891513162 (DE-599)BVBBV042067338 |
| edition | 1. ed. |
| format | Book |
| fullrecord | <?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01310nam a2200325 cc4500</leader><controlfield tag="001">BV042067338</controlfield><controlfield tag="003">DE-604</controlfield><controlfield tag="005">00000000000000.0</controlfield><controlfield tag="007">t</controlfield><controlfield tag="008">140910s2014 ad|| |||| 00||| eng d</controlfield><datafield tag="020" ind1=" " ind2=" "><subfield code="a">9780128014301</subfield><subfield code="9">978-0-12-801430-1</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(OCoLC)891513162</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-599)BVBBV042067338</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-604</subfield><subfield code="b">ger</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1="0" ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="049" ind1=" " ind2=" "><subfield code="a">DE-355</subfield><subfield code="a">DE-19</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Regulated cell death</subfield><subfield code="n">B</subfield><subfield code="p">Necroptotic, autophagic and other non-apoptotic mechanisms</subfield><subfield code="c">ed. by Avi Ashkenazi ...</subfield></datafield><datafield tag="250" ind1=" " ind2=" "><subfield code="a">1. ed.</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="a">Amsterdam [u.a.]</subfield><subfield code="b">Elsevier, Acad. Press</subfield><subfield code="c">2014</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">XIII, 337 S., [13] Bl.</subfield><subfield code="b">Ill., graph. Darst.</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="b">n</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="b">nc</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="490" ind1="1" ind2=" "><subfield code="a">Methods in enzymology</subfield><subfield code="v">545</subfield></datafield><datafield tag="490" ind1="0" ind2=" "><subfield code="a">Methods in enzymology</subfield><subfield code="v">...</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Ashkenazi, Avi</subfield><subfield code="e">Sonstige</subfield><subfield code="4">oth</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="w">(DE-604)BV042034231</subfield><subfield code="g">2</subfield></datafield><datafield tag="830" ind1=" " ind2="0"><subfield code="a">Methods in enzymology</subfield><subfield code="v">545</subfield><subfield code="w">(DE-604)BV000000938</subfield><subfield code="9">545</subfield></datafield><datafield tag="856" ind1="4" ind2="2"><subfield code="m">Digitalisierung UB Regensburg - ADAM Catalogue Enrichment</subfield><subfield code="q">application/pdf</subfield><subfield code="u">http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=027508087&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA</subfield><subfield code="3">Inhaltsverzeichnis</subfield></datafield><datafield tag="999" ind1=" " ind2=" "><subfield code="a">oai:aleph.bib-bvb.de:BVB01-027508087</subfield></datafield></record></collection> |
| id | DE-604.BV042067338 |
| illustrated | Illustrated |
| indexdate | 2024-07-10T01:11:51Z |
| institution | BVB |
| isbn | 9780128014301 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-027508087 |
| oclc_num | 891513162 |
| open_access_boolean | |
| owner | DE-355 DE-BY-UBR DE-19 DE-BY-UBM |
| owner_facet | DE-355 DE-BY-UBR DE-19 DE-BY-UBM |
| physical | XIII, 337 S., [13] Bl. Ill., graph. Darst. |
| publishDate | 2014 |
| publishDateSearch | 2014 |
| publishDateSort | 2014 |
| publisher | Elsevier, Acad. Press |
| record_format | marc |
| series | Methods in enzymology |
| series2 | Methods in enzymology |
| spelling | Regulated cell death B Necroptotic, autophagic and other non-apoptotic mechanisms ed. by Avi Ashkenazi ... 1. ed. Amsterdam [u.a.] Elsevier, Acad. Press 2014 XIII, 337 S., [13] Bl. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Methods in enzymology 545 Methods in enzymology ... Ashkenazi, Avi Sonstige oth (DE-604)BV042034231 2 Methods in enzymology 545 (DE-604)BV000000938 545 Digitalisierung UB Regensburg - ADAM Catalogue Enrichment application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=027508087&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Regulated cell death Methods in enzymology |
| title | Regulated cell death |
| title_auth | Regulated cell death |
| title_exact_search | Regulated cell death |
| title_full | Regulated cell death B Necroptotic, autophagic and other non-apoptotic mechanisms ed. by Avi Ashkenazi ... |
| title_fullStr | Regulated cell death B Necroptotic, autophagic and other non-apoptotic mechanisms ed. by Avi Ashkenazi ... |
| title_full_unstemmed | Regulated cell death B Necroptotic, autophagic and other non-apoptotic mechanisms ed. by Avi Ashkenazi ... |
| title_short | Regulated cell death |
| title_sort | regulated cell death necroptotic autophagic and other non apoptotic mechanisms |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=027508087&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| volume_link | (DE-604)BV042034231 (DE-604)BV000000938 |
| work_keys_str_mv | AT ashkenaziavi regulatedcelldeathb |