Cerebral angiogenesis: methods and protocols
Saved in:
| Format: | Book |
|---|---|
| Language: | English |
| Published: |
New York
Humana Press
2014
|
| Series: | Methods in molecular biology
1135 |
| Subjects: | |
| Online Access: | Inhaltsverzeichnis |
| Physical Description: | XV, 442 S. Ill., graph. Darst. 26 cm |
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Record in the Search Index
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| adam_text | Titel: Cerebral angiogenesis
Autor: Milner, Richard
Jahr: 2014
Contents
Preface.......................................................... v
Contributors.......................................................... xi
Part I Overview of Cerebral Angiogenesis
1 Cerebral Angiogenesis During Development:
Who Is Conducting the Orchestra?................................. 3
Ina M. Wittko-Schneider, Fabian T. Schneider, and Karl H. Plate
2 Cerebral Angiogenesis: A Realistic Therapy for Ischemic Disease?.......... 21
David A. Greenberg
3 Vascular Normalization in Cerebral Angiogenesis: Friend or Foe?.......... 25
Jisook Lee, Andrew Baird, and Brian P. Eliceiri
4 Pericytes and Adaptive Angioplasticity: The Role of Tumor Necrosis
Factor-Like Weak Inducer of Apoptosis (TWEAK)..................... 35
Paula Dore-Duffy
Part II Animal Models of Cerebral Angiogenesis
5 Analysis of Angiogenesis in the Developing Mouse
Central Nervous System......................................... 55
Nicole Ziejjler, Karl H. Plate, and Stefan Liebner
6 Hypoxia-Induced Angiogenesis and Capillary Density Determination....... 69
Constantinos P. Tsipis, Xiaoyan Sun, Kui Xu, and Joseph C. LaManna
7 The Middle Cerebral Artery Occlusion Model of Transient Focal
Cerebral Ischemia.............................................. 81
Fudong Liu and Louise D. McCullough
8 A Mouse Model of Chronic Cerebral Hypoperfusion Characterizing
Features of Vascular Cognitive Impairment........................... 95
Masafumi Ihara, Akihiko Taguchi, Takakuni Maki, Kazuo Washida,
and Hidekazu Tomimoto
9 A Mouse Model of Permanent Focal Ischemia:
Distal Middle Cerebral Artery Occlusion............................. 103
Kristian P. Doyle and Marion S. Buckwalter
10 A Method of Inducing Global Cerebral Ischemia...................... Ill
Gina Hadley, Michaiis Papadakis, and Alastair M. Buchan
11 Induction of Cerebral Arteriogenesis in Mice......................... 121
André Duelsner, Nora Gatzke, Anja Bondke Persson,
and Ivo R. Buschmann
vii
viii
Contents
12 Vessel Painting Technique for Visualizing
the Cerebral Vascular Architecture of the Mouse....................... 127
Shea Hughes, Oleksandr Dashkin, and Richard Anthony DeFazio
13 Examining Cerebral Angiogenesis in Response to Physical Exercise......... 139
KierstenL. Berggren, Jacob J.M. Kay, and Rodney A. Swain
Part III Methods of Examining Cerebral Angiogenesis
14 Histological Assessment of Angiogenesis
in the Hypoxic Central Nervous System............................. 157
Moisés Freitas-Andrade, Jacqueline Slinn, Claudie Charlebois,
and Maria J. Moreno
15 Examining Vascular Remodeling in the Hypoxic Central Nervous System .... 177
Amin Boroujerdi, Jennifer V. Welser-Alves, and Richard Milner
16 Analysis of Cerebral Angiogenesis in Human Glioblastomas.............. 187
Michel Mittelbronn, Peter Baumgarten, Patrick N. Harter,
and Karl H. Plate
17 Quantitative Cerebral Blood Flow Measurements Using MRI............. 205
Eric R. Muir, Lora Talley Watts, Tash Vardhan Tiwari,
Andrew Bresnen, Qiang Shen, and Timothy Q. Duong
18 Fluorescent Angiogenesis Models Using Gelfoam®
Implanted in Transgenic Mice Expressing Fluorescent Proteins............ 213
Robert M. Hoffman
19 Laser Speckle Contrast Imaging to Measure Changes
in Cerebral Blood Flow.......................................... 223
Ian PL Winship
20 Laser Doppler Flowmetry to Measure Changes in Cerebral Blood Flow..... 237
Brad A. Sutherland, Tamer Rabie, and Alastair M. Buchau
Part IV Determining the Role of Candidate Genes
in Cerebral Angiogenesis
21 Defining the Role of HIF and Its Downstream Mediators
in Hypoxic-Induced Cerebral Angiogenesis........................... 251
Xiaoyan Sun, Constantinos P. Tsipis, Girriso F. Benderro, Kui Xu,
and Joseph C. LaManna
22 Inducible Gene Deletion in Glial Cells to Study Angiogenesis
in the Central Nervous System.................................... 261
Hye Shin Lee and Joseph H. McCarty
23 Bone Marrow Chimera Experiments to Determine the Contribution
of Hematopoietic Stem Cells to Cerebral Angiogenesis.................. 275
Marcia Regina Machein and Karl H. Plate
Contents ix
24 Novel Methods for Accurate Identification, Isolation, and Genomic
Analysis of Symptomatic Microenvironments in Atherosclerotic Arteries..... 289
Mark Slevin, Marthel Baldellou, Elspeth Hill, Yvonne Alexander,
Garry McDowell, Christopher Murgatroyd, Michael Carroll,
Hans Degens, Jerzy Krupinski, Norma Rovira,
Mohammad Chowdhury, Ferdinand Serracino-Inglott,
and Lina Badimon
Part V Stimulation of Cerebral Angiogenesis by Gene Delivery
25 Induction of Brain Arteriovenous Malformation in the Adult Mouse........ 309
Wanqiu Chen, William L. Young, and Hua Su
26 Stimulation of Cerebral Angiogenesis by Gene Delivery................. 317
Yaohui Tang, Yaning Li, Xiaojie Lin, Peng Miao, Yongting Wang,
and Guo-Yuan Yang
27 Investigating the Role of Perlecan Domain V
in Post-Ischemic Cerebral Angiogenesis............................. 331
Aileen Marcelo and Gregory Bix
Part VI Methods to Study Cerebral Angiogenesis In Vitro
28 Isolation and Culture of Primary Mouse Brain Endothelial Cells........... 345
Jennifer V. Welser-Alves, Amin Boroujerdi, and Richard Milner
29 Purification of Endothelial Cells from Rat Brain....................... 357
Jinhua Luo, Xiangling Yin, Alma Sanchez, Debjani Tripathy,
Joseph Martinez, and Paula Grammas
30 Generation of Primary Cultures of Bovine Brain Endothelial Cells
and Setup of Cocultures with Rat Astrocytes.......................... 365
Hans C. Helms and Birger Brodin
31 Isolation and Culture of Primary Pericytes from Mouse Brain............. 383
Amin Boroujerdi, Ulrich Tigges, Jennifer V. Welser-Alves,
and Richard Milner
32 Assays to Examine Endothelial Cell Migration,
Tube Formation, and Gene Expression Profiles........................ 393
Shuzhen Guo, Josephine Lok, Yi Liu, Kazuhide Hayakawa,
Wendy Leung, Changhong Xing, Xunming Ji, and Eng H. Lo
33 A Neurovascular Blood-Brain Barrier In Vitro Model................... 403
Christoph M. Zehendner, Robin White, Jana Hedrich,
and Heiko J. Luhmann
34 In Vitro Models of the Blood-Brain Barrier.......................... 415
Cathrin J. Czupalla, Stefan Liebner, and Kavi Devraj
Index............................................................... 439
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| title | Cerebral angiogenesis methods and protocols |
| title_auth | Cerebral angiogenesis methods and protocols |
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| title_full | Cerebral angiogenesis methods and protocols ed. by Richard Milner |
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