Generation and characterization of multi-specific antibodies for therapeutic applications in oncology:
Saved in:
| Main Author: | |
|---|---|
| Format: | Thesis Book |
| Language: | English |
| Published: |
2014
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| Subjects: | |
| Online Access: | Volltext http://d-nb.info/1048361969/34 kostenfrei Inhaltsverzeichnis |
| Physical Description: | 86 S. Ill., graph. Darst. |
| Format: | Langzeitarchivierung gewährleistet, LZA |
Staff View
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| 245 | 1 | 0 | |a Generation and characterization of multi-specific antibodies for therapeutic applications in oncology |c Raffaella Castoldi |
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Record in the Search Index
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| adam_text | TABLE OF CONTENTS
1. INTRODUCTION 3
1.1 THE PATHOGENESIS OF CANCER 3
1.2 CANCER DRUG TREATMENTS: MOLECULAR TARGETED THERAPIES 6
1.3 THE BIOLOGY OF THE RECEPTOR TYROSINE KINASES EGFR AND MET: TWO
MOLECULAR TARGETS FOR
ANTI-CANCER DRUGS 9
1.3.1 THE EPIDERMAL GROWTH FACTOR RECEPTOR (EGFR/HER1) A MEMBER OF THE
HER FAMILY OF
RECEPTOR TYROSINE KINASES 9
1.3.2 THE HGF RECEPTOR MET AND ITS ROLE IN TUMOR RESISTANCE TO EGFR
INHIBITION 11
1.4 ANTIBODIES AS DRUGS 15
1.4.1 BI- AND MULTI-SPECIFIC ANTIBODIES 16
1.5 ABBREVIATIONS 21
1.6 REFERENCES 23
2. SUMMARY OF THE PRESENTED PUBLICATIONS 33
3. ZUSAMMENFASSUNG DER PRAESENTIERTEN ARBEITEN 37
4. RESULTS (PUBLICATIONS) 41
4.1 PUBLICATION: CASTOLDI R ET AL. ONCOGENE. 2013 43
4.2 PUBLICATION: CASTOLDI R, JUCKNISCHKE U ET AL. PROTEIN ENG DES SEI.
2012 69
5. ACKNOWLEDGEMENTS 83
6. PUBLICATIONS 85
6.1 PAPERS 85
6.2 POSTERS
AND PRESENTATIONS AT CONFERENCES
85
6.3 PATENT APPLICATIONS 86
HTTP://D-NB.INFO/1049719832
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| any_adam_object | 1 |
| author | Castoldi, Raffaella |
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| dewey-full | 610 |
| dewey-hundreds | 600 - Technology (Applied sciences) |
| dewey-ones | 610 - Medicine and health |
| dewey-raw | 610 |
| dewey-search | 610 |
| dewey-sort | 3610 |
| dewey-tens | 610 - Medicine and health |
| discipline | Medizin |
| format | Thesis Book |
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| spelling | Castoldi, Raffaella Verfasser aut Generation and characterization of multi-specific antibodies for therapeutic applications in oncology Raffaella Castoldi 2014 86 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier München, Univ., Diss., 2014 Langzeitarchivierung gewährleistet, LZA Mit einer Zssfassung in dt. Sprache (DE-588)4113937-9 Hochschulschrift gnd-content Erscheint auch als Online-Ausgabe urn:nbn:de:bvb:19-166251 https://nbn-resolving.org/urn:nbn:de:bvb:19-166251 Resolving-System kostenfrei Volltext http://d-nb.info/1048361969/34 Langzeitarchivierung Nationalbibliothek http://edoc.ub.uni-muenchen.de/16625/ Verlag kostenfrei DNB Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=027255011&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Castoldi, Raffaella Generation and characterization of multi-specific antibodies for therapeutic applications in oncology |
| subject_GND | (DE-588)4113937-9 |
| title | Generation and characterization of multi-specific antibodies for therapeutic applications in oncology |
| title_auth | Generation and characterization of multi-specific antibodies for therapeutic applications in oncology |
| title_exact_search | Generation and characterization of multi-specific antibodies for therapeutic applications in oncology |
| title_full | Generation and characterization of multi-specific antibodies for therapeutic applications in oncology Raffaella Castoldi |
| title_fullStr | Generation and characterization of multi-specific antibodies for therapeutic applications in oncology Raffaella Castoldi |
| title_full_unstemmed | Generation and characterization of multi-specific antibodies for therapeutic applications in oncology Raffaella Castoldi |
| title_short | Generation and characterization of multi-specific antibodies for therapeutic applications in oncology |
| title_sort | generation and characterization of multi specific antibodies for therapeutic applications in oncology |
| topic_facet | Hochschulschrift |
| url | https://nbn-resolving.org/urn:nbn:de:bvb:19-166251 http://d-nb.info/1048361969/34 http://edoc.ub.uni-muenchen.de/16625/ http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=027255011&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
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