Implantable bioelectronics:
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| Format: | Book |
| Language: | English |
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Weinheim
Wiley-VCH
2014
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| Online Access: | Inhaltstext Inhaltsverzeichnis |
| Physical Description: | XXII, 449 S. 130 schw.-w. Ill., 20 farb. Ill. 244 mm x 170 mm |
| ISBN: | 3527335250 9783527335251 9783527673148 |
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MARC
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CONTENTS
PREFACE
XV
LIST OF CONTRIBUTORS XVII
1 IMPLANTABLE BIOELECTRONICS - EDITORIAL INTRODUCTION 1
EVGENY
KATZ
REFERENCES 5
2 MAGNETICALLY FUNCTIONALIZED CELLS: FABRICATION, CHARACTERIZATION,
AND BIOMEDICAL APPLICATIONS 7
EKATERINA A. NAUMENKO, MARIA R. DZAMUKOVA, AND RAWIL F. FAKHRULLIN
2.1 INTRODUCTION 7
2.2 MAGNETIC MICROBIAL CELLS 8
2.2.1 DIRECT DEPOSITION OF MNPS ONTO MICROBIAL CELLS 8
2.2.2 POLYMER-MEDIATED DEPOSITION OF MNPS ONTO MICROBIAL CELLS 9
2.2.2.1 LAYER-BY-LAYER MAGNETIC FUNCTIONALIZATION OF MICROBIAL CELLS 9
2.2.2.2 SINGLE-STEP POLYMER-MEDIATED MAGNETIC FUNCTIONALIZATION OF
MICROBIAL CELLS 11
2.2.3 APPLICATIONS OF MAGNETICALLY MODIFIED MICROBIAL CELLS 15
2.2.3.1 BIOSORBENTS AND BIOCATALYSTS 15
2.2.3.2 WHOLE-CELL BIOSENSORS AND MICROFLUIDIC DEVICES 15
2.2.3.3 REMOTELY CONTROLLED ORGANISMS 16
2.3 MAGNETIC LABELING OF MAMMAL (HUMAN) CELLS 18
2.3.1 INTRACELLULAR LABELING OF CELLS 18
2.3.1.1 LABELING WITH ANIONIC MAGNETIC NANOPARTICLES 18
2.3.1.2 LABELING WITH CATIONIC MAGNETIC NANOPARTICLES 19
2.3.2 EXTRACELLULAR LABELING OF CELLS 20
2.3.3 APPLICATIONS OF MAGNETICALLY LABELED CELLS IN BIOMEDICINE 20
2.3.3.1 MRI IMAGING OF MNPS-LABELED CELLS 21
2.3.3.2 MNPS-MEDIATED CELL DELIVERY AND TISSUE ENGINEERING 21
HTTP://D-NB.INFO/1042297460
VII CONTENTS
2.4 CONCLUSION 23
ACKNOWLEDGMENT 23
REFERENCES 23
3 UNTETHERED INSECT INTERFACES 27
AMOL JADHAV, MICHEL M. MAHARBIZ, AND HIROTAKA SATO
3.1 INTRODUCTION 27
3.2 SYSTEMS FOR TETHERLESS INSECT FLIGHT CONTROL 30
3.2.1 VARIOUS APPROACHES TO TETHERLESS FLIGHT CONTROL 30
3.2.2 NEUROSTIMULATION FOR INITIATION OF WING OSCILLATIONS 30
3.2.3 EXTRACELLULAR STIMULATION OF THE MUSCLES TO ELICIT TURNS 32
3.3 IMPLANTABLE BIOELECTRONICS IN INSECTS 33
3.3.1 EXAMPLE: INSERTION OF FLEXIBLE SUBSTRATES INTO THE DEVELOPING EYE
33
3.4 CONCLUSIONS 39
REFERENCES 39
4 MINIATURIZED BIOMEDICAL IMPLANTABLE DEVICES 45
ADA S.Y. POON
4.1 INTRODUCTION 45
4.2 ENERGY HARVESTING AS A PATHWAY TO MINIATURIZATION 47
4.3 IMPLEMENTATION OF IMPLANTABLE DEVICES 48
4.3.1 RF POWER HARVESTING 49
4.3.1.1 MATCHING NETWORK 49
4.3.1.2 RECTIFIER 49
4.3.1.3 REGULATOR AND BANDGAP REFERENCE 50
4.3.1.4 LOW-POWER CONTROLLER AND AUXILIARY CIRCUITS IN THE IMPLANT
FUNCTIONAL BLOCK 50
4.3.2 WIRELESS COMMUNICATION LINK 51
4.3.2.1 FORWARD DATA LINK 51
4.3.2.2 REVERSE DATA LINK 54
4.3.3 PAYLOAD AND APPLICATIONS: LOCOMOTIVE IMPLANT AND IMPLANTABLE
CARDIAC PROBE 56
4.3.3.1 ACTUATION FOR THERAPEUTICS: MILLIMETER-SIZED WIRELESSLY POWERED
AND
REMOTELY CONTROLLED LOCOMOTIVE IMPLANT 56
4.3.3.2 LOW-POWER SENSING FOR DIAGNOSTICS: IMPLANTABLE INTRACARDIAC
PROBE 59
4.4 CONCLUSION 62
REFERENCES 62
5 CROSS-HIERARCHY DESIGN EXPLORATION FOR IMPLANTABLE ELECTRONICS 65
MRIGANK SHARAD AND KAUSHIK ROY
5.1 INTRODUCTION 65
5.2 SYSTEM OVERVIEW OF A GENERIC BIOELECTRONIC IMPLANT 65
5.3 CIRCUIT DESIGN FOR LOW-POWER SIGNAL PROCESSING 67
5.3.1 DESIGN CHALLENGES FOR LOW-POWER BIOELECTRONIC SENSOR INTERFACE 67
CONTENTS
I VII
5.3.2 ANALOG SIGNAL PROCESSING USING SUBTHRESHOLD CIRCUITS 68
5.3.3 ANALOG-TO-DIGITAL CONVERSION 69
5.3.4 LOW-POWER DIGITAL SIGNAL PROCESSING 71
5.3.4.1 V
DD
SCALING AND PARALLEL PROCESSING 71
5.3.4.2 DYNAMIC VOLTAGE AND FREQUENCY SCALING 72
5.3.4.3 STANDBY MODE POWER REDUCTION 73
5.3.4.4 MINIMUM ENERGY SUBTHRESHOLD OPERATION 73
5.3.5 FINFETS FOR ULTRALOW VOLTAGE SUBTHRESHOLD CIRCUITS 74
5.4 ARCHITECTURE-LEVEL OPTIMIZATIONS FOR LOW-POWER DATA PROCESSING 76
5.4.1 OPTIMAL APPORTIONING OF COMPUTATION TASK TO ANALOG AND DIGITAL
BLOCKS 76
5.4.2 APPROXIMATE COMPUTING FOR LOW POWER 78
5.5 DESIGN OF ENERGY-EFFICIENT MEMORY 79
5.5.1 DESIGN CHALLENGES WITH SUBTHRESHOLD SRAM 79
5.5.1.1 ON-CURRENT TO OFF-CURRENT RATIO 79
5.5.1.2 SIZING CONSTRAINTS 79
5.5.1.3 VARIABILITY 80
5.5.2 SPIN TRANSFER TORQUE MRAM (STT-MRAM) FOR ENERGY-EFFICIENT
MEMORY DESIGN 80
5.6 WIRELESS COMMUNICATION POWER DELIVERY 81
5.6.1 NEAR-FIELD ELECTROMAGNETIC WIRELESS COMMUNICATION
82
5.6.2 FAR-FIELD ELECTROMAGNETIC WIRELESS COMMUNICATION 82
5.6.3 WIRELESS ENERGY TRANSFER 83
5.7 CONCLUSION 83
REFERENCES 84
6 NEURAL INTERFACES: FROM HUMAN NERVES TO ELECTRONICS 87
JESSICA
D. FALCONE, JOAV BITJINIUK, ROBERT KRETSCHMAR,
AND RAVI V. BELLAMKONDA
6.1 INTRODUCTION 87
6.2 FUSING ROBOTICS WITH THE HUMAN BODY: INTERFACING WITH THE
PERIPHERAL NERVOUS SYSTEM 87
6.2.1 THE ANATOMY OF PERIPHERAL NERVES 88
6.2.1.1 GLIAL CELLS OF THE PERIPHERAL NERVOUS SYSTEM 88
6.2.1.2 FUNCTIONAL AFFERENT AND EFFERENT PATHWAYS 88
6.2.2 INTERFACING WITH THE PERIPHERY FOR RECORDING AND STIMULATION 89
6.2.2.1 NONINVASIVE ELECTRODES 89
6.2.2.2 EXTRANEURAL ELECTRODES 90
6.2.2.3 INTRAFASCICULAR ELECTRODES 91
6.2.2.4 REGENERATION-BASED ELECTRODES 92
6.2.2.5 RESEARCH DESIGNS AND CHALLENGES 92
6.3 LISTENING TO THE BRAIN: INTERFACING WITH THE CENTRAL NERVOUS
SYSTEM 93
6.3.1 GLIAL CELLS OF THE CENTRAL NERVOUS SYSTEM 93
6.3.1.1 MICROGLIA - SENTINELS OF THE BRAIN 93
VIIII
CONTENTS
6.3.1.2 ASTROCYTES - CELLULAR SUPPORT FOR NEURONS 94
6.3.2 INTERFACING WITH THE BRAIN FOR RECORDINGS 94
6.3.2.1 NONINVASIVE ELECTRODES 94
6.3.2.2 EXTRACORTICAL ELECTRODES 95
6.3.2.3 INVASIVE INTRACORTICAL ELECTRODES 95
6.3.2.4 RESEARCH DESIGNS AND CHALLENGES 97
6.4 ELECTRICAL MODULATION OF THE HUMAN NERVOUS SYSTEM: STIMULATION
AND CLINICAL APPLICATIONS 99
6.4.1 DEEP BRAIN STIMULATION 100
6.4.1.1 BIOLOGICAL MECHANISMS 100
6.4.1.2 ELECTRODE DESIGN AND STIMULATION 100
6.4.1.3 RESEARCH DESIGNS AND CHALLENGES 101
6.4.2 ELECTRICAL MODULATION OF NERVE REGENERATION 101
6.4.2.1 BIOLOGICAL MECHANISMS 102
6.4.2.2 ELECTRODE STIMULATION 102
6.4.3 PAIN MODULATION 102
6.4.3.1 BIOLOGICAL MECHANISMS 102
6.4.3.2 CLINICAL OUTCOMES 103
6.4.4 ELECTRICAL MODULATION OF INFLAMMATION 103
6.4.4.1 THE VAGUS NERVE AND STIMULATION 103
6.4.4.2 CHOLINERGIC ANTI-INFLAMMATORY PATHWAY
6.5 FUTURE DIRECTIONS FOR NEURAL INTERFACING
REFERENCES 106
7 CYBORGS
- THE NEURO-TECH VERSION 115
KEVIN WARWICK
7.1 INTRODUCTION 115
7.2 BIOLOGICAL BRAINS IN A ROBOT BODY 116
7.3 DEEP BRAIN STIMULATION 120
7.4 GENERAL PURPOSE BRAIN IMPLANTS 123
7.5 NONINVASIVE BRAIN-COMPUTER INTERFACES
7.6 SUBDERMAL MAGNETIC IMPLANTS 127
7.7 RFID IMPLANTS 128
7.8 CONCLUSIONS 130
REFERENCES 131
8 INTERACTION WITH IMPLANTED DEVICES THROUGH IMPLANTED USER
INTERFACES 133
CHRISTIAN HOLZ, TOVI GROSSMAN, GEORGE FITZMAURICE, AND ANNE AGUR
8.1 IMPLANTED USER INTERFACES 135
8.1.1 DESIGN CONSIDERATIONS 136
8.1.1.1 INPUT THROUGH IMPLANTED INTERFACES 136
8.1.1.2 OUTPUT THROUGH IMPLANTED INTERFACES 136
8.1.1.3 COMMUNICATION AND SYNCHRONIZATION 137
8.1.1.4 POWER SUPPLY THROUGH IMPLANTED INTERFACES 137
104
105
CONTENTS
IIX
8.1.2 SUMMARY 137
8.2 EVALUATING BASIC IMPLANTED USER INTERFACES 137
8.2.1 DEVICES 138
8.2.2 EXPERIMENTERS 139
8.2.3 PROCEDURE 139
8.2.4 MEDICAL PROCEDURE 139
8.2.5 STUDY PROCEDURE AND RESULTS 140
8.2.5.1 TOUCH INPUT DEVICE (PRESSURE SENSOR, TAP SENSOR, BUTTON) 140
8.2.5.2 HOVER INPUT DEVICE (CAPACITIVE AND BRIGHTNESS SENSOR) 141
8.2.5.3 OUTPUT DEVICE (RED LED, VIBRATION MOTOR) 142
8.2.5.4 AUDIO DEVICE (SPEAKER AND MICROPHONE) 144
8.2.5.5 POWERING DEVICE (POWERMAT WIRELESS CHARGER) 145
8.2.5.6 WIRELESS COMMUNICATION DEVICE (BLUETOOTH CHIP) 146
8.2.6 DISCUSSION 147
8.2.7 EXPLORING EXPOSED COMPONENTS 147
8.3 QUALITATIVE EVALUATION 148
8.3.1 SIMULATING IMPLANTS: ARTIFICIAL SKIN 148
8.3.2 TASK AND PROCEDURE 149
8.3.3 PARTICIPANTS 150
8.3.4 RESULTS 150
8.4 MEDICAL CONSIDERATIONS 150
8.4.1 LOCATION 150
8.4.2 DEVICE PARAMETERS 151
8.4.3 RISKS 151
8.4.4 IMPLICATIONS AND FUTURE STUDIES 152
8.5 DISCUSSION AND LIMITATIONS 152
8.5.1 STUDY LIMITATIONS 152
8.6 CONCLUSIONS 153
REFERENCES 153
9 ULTRALOW POWER AND ROBUST ON-CHIP DIGITAL SIGNAL PROCESSING FOR
CLOSED-LOOP NEURO-PROSTHESIS 155
SWARUP BHUNIA, ABHISHEK BASAK, SEETHARAM NARASIMHAN,
AND MARYAM SADAT HASHEMIAN
9.1 INTRODUCTION 155
9.1.1 NEURAL INTERFACES 158
9.1.2 CLOSING THE NEURAL LOOP: SIGNIFICANCE OF ON-CHIP DSP 160
9.2 ALGORITHM: A VOCABULARY-BASED NEURAL SIGNAL 162
9.2.1 ANALYSIS 162
9.2.2 SPIKE-LEVEL VOCABULARY 163
9.2.3 SPIKE DETECTION 164
9.2.4 SPIKE CHARACTERIZATION AND SORTING 166
9.2.5 BURST-LEVEL VOCABULARY 167
9.2.6 MULTICHANNEL VOCABULARY FOR BEHAVIOR-SPECIFIC PATTERNS 167
9.2.7 OUTPUT PACKET GENERATION 169
X I
CONTENTS
9.3 HARDWARE IMPLEMENTATION 171
9.3.1 WAVELET MODULE 173
9.3.1.1 VOCABULARY MODULE 177
9.3.2 AREA, POWER REDUCTION METHODOLOGIES 179
9.3.2.1 SUBTHRESHOLD VERSUS SUPER-THRESHOLD
OPERATION 181
9.3.3 IMPACT OF PROCESS VARIATIONS ON YIELD 183
9.3.3.1 PREFERENTIAL DESIGN 185
9.3.4 OVERALL DESIGN FLOW 188
9.4 SUMMARY 191
REFERENCES 191
10 IMPLANTABLE CMOS IMAGING DEVICES 195
JUN OHTA
10.1 INTRODUCTION 195
10.2 FUNDAMENTALS OF CMOS IMAGING DEVICES 198
10.2.1 PHOTOSENSORS 198
10.2.2 ACTIVE PIXEL SENSOR 199
10.2.3 LOG SENSOR 201
10.2.4 PULSE WIDTH MODULATION SENSOR 202
10.2.5 SPAD SENSOR 203
10.3 ARTIFICIAL RETINA 203
10.3.1 PRINCIPLE OF ARTIFICIAL RETINA 203
10.3.2 ARTIFICIAL RETINA BASED ON CMOS IMAGING DEVICE 204
10.4 BRAIN-IMPLANTABLE CMOS IMAGING DEVICE 210
10.4.1 MEASUREMENT METHODS FOR BRAIN ACTIVITIES 210
10.4.2 FIBER ENDOSCOPE AND HEAD-MOUNTABLE DEVICE 211
10.4.3 BRAIN-IMPLANTABLE CMOS IMAGING DEVICE 212
10.5 SUMMARY AND FUTURE DIRECTIONS 215
ACKNOWLEDGMENTS 217
REFERENCES 217
11 IMPLANTED WIRELESS BIOTELEMETRY 221
MEHMEL RASIT YUCE AND JEAN-MICHEL REDOUTE
11.1 INTRODUCTION 221
11.2 BIOTELEMETRY 223
11.2.1 INDUCTIVE LINK FOR FORWARD DATA 225
11.2.2 WIRELESS POWER LINK 226
11.2.3 IMPLANTABLE TELEMETRY LINKS 228
11.2.3.1 WIDEBAND TELEMETRY LINK 228
11.2.3.2 MULTICHANNEL NEURAL RECORDING SYSTEMS 228
11.2.3.3 WIRELESS ENDOSCOPE 230
11.3 MICROELECTRODE ARRAYS AND INTERFACE ELECTRONICS 232
11.3.1 STIMULATION FRONT ENDS 233
11.3.2 RECORDING FRONT-ENDS 238
CONTENTS
XI
11.3.2.1 INSTRUMENTATION AMPLIFIER 239
11.4 CONCLUSION 242
REFERENCES 242
12 NANO-ENABLED IMPLANTABLE DEVICE FOR IN VIVO GLUCOSE
MONITORING 247
ESTEVE JUANOLA-FELIU,
JORDI COLOMER-FARRARONS, PERE
MIRIBD-CATALA,
MANEL GONZDLEZ-PIFIERO, AND JOSEP SAMITIER
12.1 INTRODUCTION 247
12.1.1 NANOTECHNOLOGY 247
12.1.2 NANOMEDICINE 248
12.2 BIOMEDICAL DEVICES FOR IN VIVO ANALYSIS 249
12.2.1 STATE OF THE ART 249
12.2.2 THE INNOVATIVE BIOMEDICAL DEVICE 250
12.2.3 ARCHITECTURE OF THE IMPLANTABLE DEVICE 251
12.2.4 IMPLANTABLE FRONT-END ARCHITECTURE FOR IN VIVO DETECTION
BIOSENSOR
APPLICATIONS 254
12.2.4.1 ARCHITECTURE OF THE ENVISAGED SUBCUTANEOUS DEVICE 254
12.2.4.2 IMPLEMENTATION AND RESULTS 258
12.2.5 THE DIABETES CARE DEVICES MARKET 260
12.3 CONCLUSIONS AND FINAL RECOMMENDATIONS 261
REFERENCES 262
13 IMPROVING THE BIOCOMPATIBILITY OF IMPLANTABLE BIOELECTRONICS
DEVICES 265
GYMAMA SLAUGHTER
13.1 INTRODUCTION 265
13.2 IMPLANTABLE BIOELECTRONIC DEVICE MATERIALS 267
13.3 SURFACE COMPOSITION 269
13.4 RESPONSE TO IMPLANTATION 273
13.5 CONCLUSION 278
REFERENCES 279
14 ABIOTIC (NONENZYMATIC) IMPLANTABLE BIOFUEL CELLS 285
SVEN KERZENMACHER
14.1 INTRODUCTION 285
14.1.1 THE HISTORY OF IMPLANTABLE ABIOTIC FUEL CELLS 285
14.2 BASIC PRINCIPLES 286
14.2.1 ELECTRODE REACTIONS AND THEORETICAL POTENTIALS 287
14.2.2 PRACTICAL FUEL CELL VOLTAGE, POWER DENSITY, AND EFFICIENCY 289
14.2.3 RELIABLE CHARACTERIZATION OF IMPLANTABLE GLUCOSE FUEL CELLS 291
14.3 ABIOTIC CATALYST MATERIALS AND SEPARATOR MEMBRANES 292
14.3.1 ELECTROCATALYSTS FOR GLUCOSE OXIDATION 292
14.3.2 ELECTROCATALYSTS FOR OXYGEN REDUCTION 293
14.3.3 SEPARATOR MEMBRANES 294
XII I CONTENTS
14.4 DESIGN CONSIDERATIONS 295
14.4.1 SITE OF IMPLANTATION 295
14.4.2 STRATEGIES TO COPE WITH THE PRESENCE OF MIXED REACTANTS 297
14.5 STATE-OF-THE-ART AND PRACTICAL EXAMPLES 299
14.5.1 COMPARISON OF FUEL CELL DESIGNS AND THEIR POWER DENSITIES 299
14.5.2 FACTORS AFFECTING LONG-TERM OPERATION 304
14.6 CONCLUSION AND OUTLOOK 307
14.6.1 STATE-OF THE-ART 307
14.6.2 APPLICATIONS 308
14.6.3 CHALLENGES AND FUTURE TRENDS 309
REFERENCES 309
15 DIRECT-ELECTRON-TRANSFER-BASED ENZYMATIC FUEL CELLS IN VITRO, EX
VIVO,
AND IN VIVO 315
MAGNUS FALK, DMITRY PANKRATOV, ZOLTAN BLUM, AND SERGEY SHLEEV
15.1 INTRODUCTION 315
15.2 OXIDOREDUCTASES FOR DIRECT-ELECTRON-TRANSFER-BASED BIODEVICES 316
15.2.1 ANODIC BIOELEMENTS 317
15.2.2 CATHODIC BIOELEMENTS 321
15.3 DESIGN OF ENZYME-BASED BIODEVICES 323
15.3.1 ELECTRODE MATERIAL 325
15.3.2 ELECTRODE FUNCTION 327
15.4 EXAMPLES OF DIRECT ELECTRON TRANSFER ENZYMATIC FUEL CELLS 329
15.4.1 ENZYMATIC FUEL CELLS OPERATING IN VITRO 329
15.4.2 BIODEVICES OPERATING IN VIVO 334
15.4.3 ENZYMATIC FUEL CELLS OPERATING EX VIVO 336
15.4.4 SUMMARY 339
15.5 OUTLOOK 340
REFERENCES 341
16 ENZYMATIC FUEL CELLS: FROM DESIGN TO IMPLANTATION IN MAMMALS 347
SERGE COSNIER, ALAN LE GOJF, AND MICHAEL
HOLZINGER
16.1 INTRODUCTION 347
16.2 DESIGN OF IMPLANTABLE BIOELECTRODES OF GLUCOSE BIOFUEL CELLS 352
16.3 PACKAGING OF IMPLANTED BIOFUEL CELLS 356
16.4 SURGERY 358
16.5 IMPLANTED BIOFUEL CELL PERFORMANCES 359
REFERENCES 361
17 IMPLANTED BIOFUEL CELLS OPERATING IN VIVO 363
EVGENY
KATZ
17.1 IMPLANTED BIOFUEL CELLS 363
ACKNOWLEDGMENT 377
REFERENCES 377
CONTENTS
J XIII
18 BIOMEDICAL IMPLANTABLE SYSTEMS - HISTORY, DESIGN, AND TRENDS 381
WEN H. KO AND PHILIP X.-L. FENG
18.1 INTRODUCTION 381
18.2 HISTORY: REVIEW OF IMPLANT SYSTEMS 383
18.2.1 HISTORICAL REVIEW OF EARLY IMPLANT SYSTEMS, 1950-1970 384
18.2.1.1 HISTORICAL REVIEW OF EARLY IMPLANT TELEMETRY SYSTEMS,
1950-1970 384
18.2.1.2 HISTORICAL REVIEW OF EARLY IMPLANT STIMULATION SYSTEMS,
1950-1970 391
18.2.1.3 HISTORICAL REVIEW OF EARLY IMPLANT CONTROL SYSTEMS, 1950-1970
391
18.2.2 HISTORICAL REVIEW OF IMPLANT SYSTEMS -1970-1990 394
18.2.3 HISTORICAL REVIEW OF IMPLANT SYSTEMS - 1990-2012 395
18.3 DESIGN OF IMPLANT SYSTEMS 396
18.3.1 BASIC CONSIDERATIONS AND CHARACTERISTICS OF RF MEMS IMPLANTABLE
SYSTEMS 397
18.3.1.1 LEGAL CONSIDERATIONS OF THE RADIO FREQUENCY (RF), FIELD
STRENGTH,
AND POWER LEVELS 397
18.3.1.2 BIOCOMPATIBILITY AND PROTECTION OF THE BIOMEDICAL IMPLANT
SYSTEMS 398
18.3.1.3 CHARACTERISTICS OF BIOLOGICAL AND MEDICAL SIGNALS 399
18.3.2 DESIGN CONSIDERATIONS OF IMPLANTABLE SYSTEMS 400
18.3.3 MICROPOWER ELECTRONIC DESIGN APPROACHES AND SAMPLES 401
18.3.4 POWER SUPPLY DESIGN 403
18.3.5 SYSTEM INTEGRATION AND MICRO-PACKAGING 404
18.4 PRESENT CHALLENGES 405
18.5 FUTURE TRENDS 406
ACKNOWLEDGMENTS 407
REFERENCES 407
19 BRAIN-COMPUTER INTERFACES: ETHICAL AND POLICY CONSIDERATIONS 411
ELLEN M. MCGEE
19.1 INTRODUCTION 411
19.2 NEUROETHICS 412
19.3 BRAIN-COMPUTER INTERFACES 412
19.4 NONINVASIVE INTERFACES 413
19.5 PARTIALLY INVASIVE INTERFACES 413
19.6 INVASIVE INTERFACES 413
19.7 DEVELOPMENT OF BRAIN-COMPUTER INTERFACES 414
19.8 THERAPY/ENHANCEMENT 418
19.9 ETHICAL ISSUES 419
19.10 BRAIN CHIPS AND CLONING 420
19.11 REGULATORY PROCEDURES 424
19.12 PRINCIPLES AND STANDARDS FOR ADOPTION 426
REFERENCES 430
XIV
|
CONTENTS
20 CONCLUSIONS AND PERSPECTIVES 435
EVGENY KATZ
REFERENCES 436
INDEX 437 |
| any_adam_object | 1 |
| author2 | Katz, Evgeny |
| author2_role | edt |
| author2_variant | e k ek |
| author_GND | (DE-588)1024192385 |
| author_facet | Katz, Evgeny |
| building | Verbundindex |
| bvnumber | BV041736009 |
| classification_rvk | YI 3200 |
| ctrlnum | (OCoLC)878007881 (DE-599)DNB1042297460 |
| dewey-full | 617.4830592 |
| dewey-hundreds | 600 - Technology (Applied sciences) |
| dewey-ones | 617 - Surgery & related medical specialties |
| dewey-raw | 617.4830592 |
| dewey-search | 617.4830592 |
| dewey-sort | 3617.4830592 |
| dewey-tens | 610 - Medicine and health |
| discipline | Chemie / Pharmazie Medizin |
| format | Book |
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| genre | (DE-588)4143413-4 Aufsatzsammlung gnd-content |
| genre_facet | Aufsatzsammlung |
| id | DE-604.BV041736009 |
| illustrated | Illustrated |
| indexdate | 2024-08-03T01:20:24Z |
| institution | BVB |
| isbn | 3527335250 9783527335251 9783527673148 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-027182707 |
| oclc_num | 878007881 |
| open_access_boolean | |
| owner | DE-29 |
| owner_facet | DE-29 |
| physical | XXII, 449 S. 130 schw.-w. Ill., 20 farb. Ill. 244 mm x 170 mm |
| publishDate | 2014 |
| publishDateSearch | 2014 |
| publishDateSort | 2014 |
| publisher | Wiley-VCH |
| record_format | marc |
| spelling | Implantable bioelectronics Weinheim Wiley-VCH 2014 XXII, 449 S. 130 schw.-w. Ill., 20 farb. Ill. 244 mm x 170 mm txt rdacontent n rdamedia nc rdacarrier Implantiertes medizinisches Gerät (DE-588)4161411-2 gnd rswk-swf Medizinische Elektronik (DE-588)4169214-7 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content Implantiertes medizinisches Gerät (DE-588)4161411-2 s Medizinische Elektronik (DE-588)4169214-7 s DE-604 Katz, Evgeny (DE-588)1024192385 edt Erscheint auch als Online-Ausgabe, EPUB 978-3-527-67316-2 Erscheint auch als Online-Ausgabe, MOBI 978-3-527-67315-5 Erscheint auch als Online-Ausgabe, PDF 978-3-527-67317-9 X:MVB text/html http://deposit.dnb.de/cgi-bin/dokserv?id=4462464&prov=M&dok_var=1&dok_ext=htm Inhaltstext DNB Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=027182707&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Implantable bioelectronics Implantiertes medizinisches Gerät (DE-588)4161411-2 gnd Medizinische Elektronik (DE-588)4169214-7 gnd |
| subject_GND | (DE-588)4161411-2 (DE-588)4169214-7 (DE-588)4143413-4 |
| title | Implantable bioelectronics |
| title_auth | Implantable bioelectronics |
| title_exact_search | Implantable bioelectronics |
| title_full | Implantable bioelectronics |
| title_fullStr | Implantable bioelectronics |
| title_full_unstemmed | Implantable bioelectronics |
| title_short | Implantable bioelectronics |
| title_sort | implantable bioelectronics |
| topic | Implantiertes medizinisches Gerät (DE-588)4161411-2 gnd Medizinische Elektronik (DE-588)4169214-7 gnd |
| topic_facet | Implantiertes medizinisches Gerät Medizinische Elektronik Aufsatzsammlung |
| url | http://deposit.dnb.de/cgi-bin/dokserv?id=4462464&prov=M&dok_var=1&dok_ext=htm http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=027182707&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| work_keys_str_mv | AT katzevgeny implantablebioelectronics |