The myc gene: methods and protocols
Saved in:
| Format: | Book |
|---|---|
| Language: | English |
| Published: |
New York
Humana Press
2013
|
| Series: | Methods in molecular biology
1012 |
| Subjects: | |
| Online Access: | Inhaltsverzeichnis |
| Item Description: | Includes bibliographical references and index |
| Physical Description: | XI, 282 S. Ill., graph. Darst. 26 cm |
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Record in the Search Index
| _version_ | 1804151873608876033 |
|---|---|
| adam_text | Titel: The Myc gene
Autor: Soucek, Laura
Jahr: 2013
Contents
Preface.................................................................................................................... v
Contributors.................................................................................................................... ix
1 The Myc World Within Reach.......................................................................... 1
Nicole M. Sodir and Laura Soucek
2 Methods for the Expression, Purification, Preparation,
and Biophysical Characterization of Constructs of the c-Myc
and Max b-HLH-LZs....................................................................................... 7
Marie-Eve Beaulieu, François-Olivier McDuff, Mikaël Bédard,
Martin Montagne, and Pierre Lavigne
3 Analyzing Myc in Cell Transformation and Evolution....................................... 21
Markus Hartl and Klaus Bister
4 Identifying Myc Interactors.............................................................................. 51
Romina Ponzielli, William B. Tu, Igor Jurisica, and Linda Z. Penn
5 Detection of c-Myc Protein-Protein Interactions and Phosphorylation
Status by Immunoprecipitation......................................................................... 65
Colin J. Daniel, Xiaoli Zhang, and Rosalie C. Sears
6 An Efficient Way of Studying Protein-Protein Interactions
Involving HIF-a, c-Myc, and Spi..................................................................... 77
Kenneth K.-W. To and L. Eric Huang
7 Methods for Determining Myc-Induced Apoptosis........................................... 85
Dan Lu and Trevor D. Littlewood
8 Methods to Study Myc-Regulated Cellular Senescence...................................... 99
Vedrana Tabor, Matteo Bocci, and Lars-Gunnar Larsson
9 Chromatin Immunoprecipitation Assays for Myc and N-Myc............................ 117
Bonnie L. Barrilleaux, Rebecca Cotterman, and Paul S. Knoepfler
10 Methods to Quantify microRNAs in the Myc Gene Network
for Posttranscriptional Gene Repression............................................................ 135
Rui Song, Nicole Sponer, and Lin He
11 Genome-Wide Analysis of c-MYC-Regulated mRNAs and miRNAs,
and c-MYC DNA Binding by Next-Generation Sequencing.............................. 145
Rene Jackstadt, Antje Menssen, and Heiko Hermeking
12 A High-Throughput siRNA Screening Platform to Identify MYC-Svnthetic
Lethal Genes as Candidate Therapeutic Targets................................................ 187
Carla Grandori
vii
viii
Contents
13 Investigating Myc-Dependent Translational Regulation in Normal
and Cancer Cells.............................................................................................. 201
John T. Cunningham, Michael Pourdehnad, Craig R. Stumpf,
and Davide Ruggero
14 Studying Myc s Role in Metabolism Regulation................................................ 213
Anne Le and Chi V. Dang
15 Generation of a Tetracycline Regulated Mouse Model of MYC-Induced
T-Cell Acute Lymphoblastic Leukemia............................................................. 221
Kavya Rakhra and Dean W. Felsher
16 Methods to Assess Myc Function in Intestinal Homeostasis, Regeneration,
and Tumorigenesis........................................................................................... 237
David J. Huels, Patrizia Cammareri, Rachel A. Ridgway,
Jan P. Medema, and Owen J. Sansom
17 Detection of c-myc Amplification in Formalin-Fixed Paraffin-Embedded
Tumor Tissue by Chromogenic In Situ Hybridization (CISH).......................... 249
Natasa Todorovic-Rakovic
18 Cell-Based Methods for the Identification
of MYC-Inhibitory Small Molecules................................................................. 255
Catherine A. Burkhart, Michelle Haber, Murray D. Norris,
Andrei V. Gudkov, and Mikhail A. Nikiforov
Index............................................................................................................................... 265
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| id | DE-604.BV041647410 |
| illustrated | Illustrated |
| indexdate | 2024-07-10T01:01:44Z |
| institution | BVB |
| language | English |
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| owner_facet | DE-12 |
| physical | XI, 282 S. Ill., graph. Darst. 26 cm |
| publishDate | 2013 |
| publishDateSearch | 2013 |
| publishDateSort | 2013 |
| publisher | Humana Press |
| record_format | marc |
| series | Methods in molecular biology |
| series2 | Methods in molecular biology Springer protocols |
| spelling | The myc gene methods and protocols ed. by Laura Soucek, Nicole M. Sodir New York Humana Press 2013 XI, 282 S. Ill., graph. Darst. 26 cm txt rdacontent n rdamedia nc rdacarrier Methods in molecular biology 1012 Springer protocols Includes bibliographical references and index Genes, myc / Laboratory Manuals Soucek, Laura Sonstige (DE-588)1047826712 oth Sodir, Nicole M. Sonstige oth Methods in molecular biology 1012 (DE-604)BV035362695 1012 HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=027088104&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | The myc gene methods and protocols Methods in molecular biology Genes, myc / Laboratory Manuals |
| title | The myc gene methods and protocols |
| title_auth | The myc gene methods and protocols |
| title_exact_search | The myc gene methods and protocols |
| title_full | The myc gene methods and protocols ed. by Laura Soucek, Nicole M. Sodir |
| title_fullStr | The myc gene methods and protocols ed. by Laura Soucek, Nicole M. Sodir |
| title_full_unstemmed | The myc gene methods and protocols ed. by Laura Soucek, Nicole M. Sodir |
| title_short | The myc gene |
| title_sort | the myc gene methods and protocols |
| title_sub | methods and protocols |
| topic | Genes, myc / Laboratory Manuals |
| topic_facet | Genes, myc / Laboratory Manuals |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=027088104&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
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