Biofabrication: micro- and nano-fabrication, printing, patterning and assemblies
Saved in:
| Other Authors: | |
|---|---|
| Format: | Book |
| Language: | English |
| Published: |
Amsterdam [u.a.]
William Andrew Elsevier
2013
|
| Series: | Micro & nano technologies series
|
| Subjects: | |
| Online Access: | Inhaltsverzeichnis Klappentext |
| Physical Description: | XVII, 265 S. |
| ISBN: | 9781455728527 |
Staff View
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| adam_text | Contents
Preface
............................................................................................................xi
List of Contributors
.....................................................................................xiii
CHAPTER
1
In Vitro
Biofabrication
of Tissues and Organs
...............
ι
Introduction
..............................................................................................1
1.1
Problems with scaffold-based tissue engineering
............................3
1.1.1
Immune reactions
..................................................................3
1.1.2
Degradation of scaffolds in vivo
..........................................3
1.1.3
Risk of infection
....................................................................4
1.2
Scaffold-free tissue engineering
...................................................5
1.2.1
Classification of present scaffold-free systems
....................6
1.2.2
In vitro self-produced ECM-rich
scaffold-free constructs
.......................................................10
1.2.3
The rotating wall vessel bioreactor system
........................11
13
Aggregation/spheroid-based approaches
.......................................11
1.3.1
Preparation of multicellular spheroids
................................12
1.3.2
Molding MCSs
....................................................................12
1.3.3
Bio-printing
.........................................................................12
1.3.4
Alternative approach for MCS assembly technique
for biofabrication
.................................................................13
Conclusion
..............................................................................................14
References
..............................................................................................16
CHAPTER
2
Biomaterials
for
Biofabrication
of
3D
Tissue Scaffolds
.........................................................23
Introduction
............................................................................................23
2.1
Materials for
3D
tissue scaffolds
...................................................24
2.1.1
Biodegradable synthetic polymers
......................................25
2.1.2
Natural polymers
.................................................................26
2.1.3
Biodegradable or resorbable ceramics
................................28
2.2
Fabrication methods for
3D
tissue scaffolds
.................................29
2.2.1
Conventional techniques for
3D
scaffolds
..........................29
2.2.2
Advanced techniques for
3D
scaffolds
...............................30
23
Application of
3D
tissue scaffolds
.................................................33
2.3.1
Decellularized iiving tissues and organs
............................34
2.3.2
Porous scaffolds with irregular pores
.................................34
vi
Contents
2.3.3
Nanofibrous
scaffolds
..........................................................35
2.3.4
Solid free-form (sff) scaffolds
............................................38
2.3.5
Hydrogel scaffolds
..............................................................40
2.4
Future perspectives of
biomaterials
for
3D
scaffolds
...................41
Conclusion
..............................................................................................42
Acknowledgment
...................................................................................42
References
..............................................................................................42
CHAPTER
3
Projection Printing of Three-Dimensional
Tissue Scaffolds with Tunable Poisson s Ratio
...........47
Introduction
............................................................................................47
3.1
Digital micromirror-assisted projection
printing stereolithography
..............................................................48
3.2
Negative Poisson s ratio
biomaterials
............................................50
3.3
Hybrid Poisson s ratio
biomaterial
................................................52
3.4
Zero Poisson s ratio
biomaterials
..................................................54
Conclusion
..............................................................................................55
References
..............................................................................................55
CHAPTER
4
Fabrication of
Microscale
Hydrogels
for
Tissue Engineering Applications
...................................59
Introduction
............................................................................................59
4.1
Technologies for fabrication of microengineered
hydrogels
........................................................................................61
4.1.1
Photolithography
.................................................................61
4.1.2
Soft lithography
...................................................................61
4.1.3
Bioprinting
...........................................................................63
4.1.4
Microfluidics
.......................................................................64
4.1.5
Emulsification
.....................................................................64
4.2
Tissue engineering applications
.....................................................65
4.2.1
Applications of photolithography in tissue
engineering
..........................................................................65
4.2.2
Applications of soft lithography in tissue
engineering
..........................................................................67
4.2.3
Applications of bioprinting in tissue engineering
..............70
4.2.4
Applications of microfluidics in tissue
engineering
..........................................................................71
4.2.5
Applications of emulsification in tissue
engineering
..........................................................................73
Contents
vìi
Conclusion
..............................................................................................74
Acknowledgments
..................................................................................75
References
..............................................................................................75
CHAPTER
5
Polymeric Membranes for the
Biofabrication
of Tissues and Organs
.....................................................81
Introduction
............................................................................................81
5.1
Properties of polymeric membranes
..............................................82
5.2
Membranes for tissue engineering
.................................................84
5.3
Hollow fiber polymeric membranes for cell
and tissue
perfusion
........................................................................87
5.4
Membrane bioreactors for tissue constructs
..................................88
5.5
Future perspectives
.........................................................................92
References
..............................................................................................92
CHAPTER
6
Laser-Assisted Bioprinting for Tissue
Engineering
.......................................................................95
Introduction
............................................................................................96
6.1
LAB s terms of reference
..............................................................98
6.1.1
Workstation requirements
...................................................98
6.1.2
Droplet ejection mechanism
.............................................101
6.2
LAB parameters for cell printing
.................................................105
6.2.1
Bioink composition considerations
...................................105
6.2.2
Viscosity of the bioink and laser energy
influence cell viability
.......................................................105
6.3
High-resolution/high-throughput trade-offs
.................................106
6.3.1
Tissue engineering needs versus LAB limits
...................106
6.3.2
Printing resolution
.............................................................106
6.3.3
High cell density printing with cell-level
resolution
...........................................................................107
6.4
Three-dimensional printing: the layer-by-layer
approach
.......................................................................................110
6A1 The bioink as a scaffold
....................................................110
6.4.2
Biopapers
...........................................................................11
1
6.5
Applications
..................................................................................112
6.5.1
Multicolor printing at the
microscale
...............................112
6.5.2
LAB engineered stem cell niche and tissue chips
............112
6.5.3
Addressing the
perfusion
issue in tissue
engineering
........................................................................112
viii Contents
6.5.4
Laser-assisted engineering of transplants
.........................113
6.5.5
In vivo printing
..................................................................113
Conclusion
............................................................................................114
Acknowledgments
................................................................................115
References
............................................................................................115
CHAPTER
7
The Modular Approach
..................................................119
Introduction
..........................................................................................119
7.1
Materials used to fabricate the modular building blocks
............121
7.1.1
ECM-based materials
........................................................123
7.1.2
PEG-based materials
.........................................................125
7.2
Intrinsically vascularized tissue constructs
..................................126
7.2.1
In vivo fate of endothelialized modules
...........................126
7.2.2
Cell sheet technology
........................................................131
7.2.3
In vitro modular tissue engineering
..................................132
7.3
Building tissue constructs by assembling building
blocks
............................................................................................133
7.3.1
Self-assembly of modules
.................................................133
7.3.2
Directed assembly of modules
..........................................136
7.4
Modular tissue engineering combined with microfluidics
..........141
Conclusion
............................................................................................143
References
............................................................................................144
CHAPTER
8
Formation of Multicellular
Microtissues
and Applications in
Biofabrication
..............................
И9
Introduction
..........................................................................................149
8.1
Materials and methods
.................................................................152
8.2
Results
..........................................................................................154
8.3
Discussion
.....................................................................................157
8.4
Future considerations
...................................................................162
References
............................................................................................164
CHAPTER
9
A Digital Microfabrication-Based System for
the Fabrication of Cancerous Tissue Models
.............167
Introduction
..........................................................................................167
9.1
Digital micro-mirroring
microfabrication
system
.......................169
9.1.1
Digital micro-mirroring projection system
.......................169
9.1.2
Photolithographic substrate alignment system
.................171
Contents ix
9.2 Multinozzle
biologies deposition system
...................................171
9.3
Methods and materials
...............................................................172
9.3.1
Fabrication protocols and cell cultures
...........................173
9.4
Results
........................................................................................175
9.4.1
Preliminary investigation
................................................175
9.4.2
Cancer model investigation
.............................................177
Conclusion
............................................................................................180
References
............................................................................................180
CHAPTER
10
Breast Reconstruction Using
Biofabrication-Based Tissue Engineering
Strategies
......................................................................183
introduction
..........................................................................................184
10.1
Anatomy of the breast
................................................................184
10.2
Current methods of breast reconstruction
..................................184
10.2.1
Prosthetic implant-based reconstruction
.......................185
10.2.2
Cellular breast reconstruction
.......................................186
10.3
Biofabrication-based tissue engineering strategy
......................189
10.3.1
Engineering challenges
.................................................189
10.3.2
Formation of tissue constructs
......................................196
Conclusion
............................................................................................205
References
............................................................................................207
CHAPTER
11
Fabrication of Artificial Bacteria for
Targeted Drug Delivery
................................................217
Introduction
..........................................................................................218
11.1
Drug delivery
..............................................................................218
11.1.1
Active and passive drug delivery
..................................219
11.1.2
Targeted drug delivery using microrobotics
.................219
11.1.3
Interaction with biomechanical
microstructures
of soft biological tissues
...............................................221
11.2
Bioinspired locomotion and microswimming
...........................222
11.2.1 Ragella..........................................................................222
11.3
Materials and methods
...............................................................225
11.3.1
Microswimmer fabrication
............................................226
11.3.2
Microswimmer structures
..............................................230
Conclusion
............................................................................................232
Contents
Acknowledgment
..............
,
..................................................................233
References
............................................................................................234
CHAPTER
12
Biofabricating the Bio-Device Interface Using
Biological Materials and Mechanisms
.....................239
Introduction
..........................................................................................239
12.1
Complementarity of
biofabrication
and
microfabrication
.........................................................................240
12.2
Biofabrication
methods
..............................................................241
12.2.1
Self-assembly
................................................................241
12.2.2
Enzymatic-assembly
......................................................243
12.2.3
Biomolecular engineering
.............................................246
123
Biofabrication
of a multifunctional matrix
................................246
12.4
Postfabrication biofunctionalization
of devices
.........................248
12.5
Test device
..................................................................................249
12.6
Electroaddressing a biosensing enzyme
....................................249
12.7
Creation of a spatially segregated bacterial
biofilm
........................................................................................252
Conclusion
............................................................................................253
Acknowledgment
.................................................................................254
References
............................................................................................254
Index
.............................................................................................................259
NANOTECHNOLOGY
BIOFABRICATION
Micro- and Nano-Fabrication, Printing, Patterning, and Assemblies
Edited by
Gabor
Forgács
and Wei Sun
Discover the multidisciplinary toolkit provided by
biofabrication
and apply it to
develop new products, techniques and therapies.
Biofabrication
is a novel, inherently cross-disciplinary scientific field that focuses
on biomanufacturing processes. This is the first book that presents the range
of biofabrication technologies
-
including cell printing, patterning, assembling,
3D
scaffold fabrication and cell/tissue-on-chips
-
as a coherent
тісго^/папо-
fabrication toolkit.
Written and edited by leaders in the field.
Biofabrication ¡s a
practical guide to
these key emerging technologies, with real-world examples to help readers gain
a working knowledge of how to apply biofabrication techniques in areas such as
regenerative medicine, Pharmaceuticals and tissue engineering.
The book introduces the most salient approaches and methods used by
practitioners of this discipline, which generates models, systems, devices,
interfaces, and products that can be used for a wide range of applications in
tissue science and tissue engineering, disease pathogeneses studies, and the
development of new drugs.
In addition to being a vital reference for scientists, engineers and technicians
seeking to apply biofabrication techniques, this book also provides an insight into
future developments in the field, and potential new applications.
Gabor
Forgács
is the George Vineyard Professor of Biological Physics at the
University of Missouri, Director of the Shipley Center for Innovation at
Clarkson
University and co-founder of the biotech companies Organovo and Modern
Meadow. He received his PhD in theoretical physics from the Roland Eotvos
University, Budapest, Hungary and the Landau institute for Theoretical Physics,
Moscow, Russia. His present research focuses on physical mechanisms in early
embryonic development, which he is applying to building functional living
structures using tissue engineering technologies, such as bioprinting, which
he pioneered. He has been recognized with numerous awards and citations,
in particular, by FastCompany as one of the
100
most innovative people in business
in
2010 .
Wei Sun received his PhD in Mechanical Engineering in
1992
from Drexel
University, USA. He is currently Albert
Soffa
Chair Professor at the Department of
Mechanical Engineering and Mechanics, Drexel University, USA, and Professor of
Mechanical Engineering and Director of Biomanufacturing Engineering Research
Institute in Tsinghua University, Beijing, China. Dr. Sun s research interests include
Biomanufacturing, Computer-Aided Tissue Engineering,
CAD
/САМ
and Additive
Manufacturing. He is currently an elected President of International Society of
Biofabrication, and serves as Editor-in-Chief for the journal Biofabrication.
Micro-Drops and Digital Microfluidics 2e
{2013),
Berthier,
9781455725502
Microffuidic Celt Culture Systems
(2013),
Bettinger, Borenstein and Tao,
9781437734591
William
Andrew
www.williarnandrewcum
|
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| bvnumber | BV041293749 |
| classification_rvk | YI 3200 ZM 9000 |
| ctrlnum | (OCoLC)855042151 (DE-599)OBVAC11036494 |
| dewey-full | 660.6 |
| dewey-hundreds | 600 - Technology (Applied sciences) |
| dewey-ones | 660 - Chemical engineering |
| dewey-raw | 660.6 |
| dewey-search | 660.6 |
| dewey-sort | 3660.6 |
| dewey-tens | 660 - Chemical engineering |
| discipline | Chemie / Pharmazie Werkstoffwissenschaften / Fertigungstechnik Medizin |
| format | Book |
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| id | DE-604.BV041293749 |
| illustrated | Not Illustrated |
| indexdate | 2024-07-10T00:53:34Z |
| institution | BVB |
| isbn | 9781455728527 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-026742682 |
| oclc_num | 855042151 |
| open_access_boolean | |
| owner | DE-703 DE-29T DE-20 |
| owner_facet | DE-703 DE-29T DE-20 |
| physical | XVII, 265 S. |
| publishDate | 2013 |
| publishDateSearch | 2013 |
| publishDateSort | 2013 |
| publisher | William Andrew Elsevier |
| record_format | marc |
| series2 | Micro & nano technologies series |
| spelling | Biofabrication micro- and nano-fabrication, printing, patterning and assemblies ed. by Gabor Forgacs ... Amsterdam [u.a.] William Andrew Elsevier 2013 XVII, 265 S. txt rdacontent n rdamedia nc rdacarrier Micro & nano technologies series Medizin-Technik (DE-588)2071813-5 gnd rswk-swf 3D-Druck (DE-588)1032223197 gnd rswk-swf Herstellung (DE-588)4159653-5 gnd rswk-swf Biopolymere (DE-588)4006893-6 gnd rswk-swf Werkstoff (DE-588)4065579-9 gnd rswk-swf Biomaterial (DE-588)4267769-5 gnd rswk-swf Rapid Prototyping Fertigung (DE-588)4389159-7 gnd rswk-swf Biomedizinische Technik (DE-588)4006882-1 gnd rswk-swf Bioengineering. Biomedizinische Technik (DE-588)4006882-1 s Biomaterial (DE-588)4267769-5 s Herstellung (DE-588)4159653-5 s DE-604 Rapid Prototyping Fertigung (DE-588)4389159-7 s Werkstoff (DE-588)4065579-9 s Medizin-Technik (DE-588)2071813-5 f Biopolymere (DE-588)4006893-6 s 3D-Druck (DE-588)1032223197 s Forgacs, Gabor edt Digitalisierung UB Bayreuth - ADAM Catalogue Enrichment application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=026742682&sequence=000003&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis Digitalisierung UB Bayreuth - ADAM Catalogue Enrichment application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=026742682&sequence=000004&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA Klappentext |
| spellingShingle | Biofabrication micro- and nano-fabrication, printing, patterning and assemblies Medizin-Technik (DE-588)2071813-5 gnd 3D-Druck (DE-588)1032223197 gnd Herstellung (DE-588)4159653-5 gnd Biopolymere (DE-588)4006893-6 gnd Werkstoff (DE-588)4065579-9 gnd Biomaterial (DE-588)4267769-5 gnd Rapid Prototyping Fertigung (DE-588)4389159-7 gnd Biomedizinische Technik (DE-588)4006882-1 gnd |
| subject_GND | (DE-588)2071813-5 (DE-588)1032223197 (DE-588)4159653-5 (DE-588)4006893-6 (DE-588)4065579-9 (DE-588)4267769-5 (DE-588)4389159-7 (DE-588)4006882-1 |
| title | Biofabrication micro- and nano-fabrication, printing, patterning and assemblies |
| title_auth | Biofabrication micro- and nano-fabrication, printing, patterning and assemblies |
| title_exact_search | Biofabrication micro- and nano-fabrication, printing, patterning and assemblies |
| title_full | Biofabrication micro- and nano-fabrication, printing, patterning and assemblies ed. by Gabor Forgacs ... |
| title_fullStr | Biofabrication micro- and nano-fabrication, printing, patterning and assemblies ed. by Gabor Forgacs ... |
| title_full_unstemmed | Biofabrication micro- and nano-fabrication, printing, patterning and assemblies ed. by Gabor Forgacs ... |
| title_short | Biofabrication |
| title_sort | biofabrication micro and nano fabrication printing patterning and assemblies |
| title_sub | micro- and nano-fabrication, printing, patterning and assemblies |
| topic | Medizin-Technik (DE-588)2071813-5 gnd 3D-Druck (DE-588)1032223197 gnd Herstellung (DE-588)4159653-5 gnd Biopolymere (DE-588)4006893-6 gnd Werkstoff (DE-588)4065579-9 gnd Biomaterial (DE-588)4267769-5 gnd Rapid Prototyping Fertigung (DE-588)4389159-7 gnd Biomedizinische Technik (DE-588)4006882-1 gnd |
| topic_facet | Medizin-Technik 3D-Druck Herstellung Biopolymere Werkstoff Biomaterial Rapid Prototyping Fertigung Biomedizinische Technik |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=026742682&sequence=000003&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=026742682&sequence=000004&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA |
| work_keys_str_mv | AT forgacsgabor biofabricationmicroandnanofabricationprintingpatterningandassemblies |