Metabolic syndrome: an important risk factor for stroke, Alzheimer disease, and depression
Saved in:
| Main Author: | |
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| Format: | Electronic eBook |
| Language: | English |
| Published: |
New York, NY
Springer
2013
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| Subjects: | |
| Online Access: | FAN01 UBT01 Volltext Inhaltsverzeichnis Abstract |
| Physical Description: | 1 Online-Ressource |
| ISBN: | 9781461473176 9781461473183 |
| DOI: | 10.1007/978-1-4614-7318-3 |
Staff View
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Record in the Search Index
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| adam_text | METABOLIC SYNDROME
/ FAROOQUI, AKHLAQ A.
: 2013
TABLE OF CONTENTS / INHALTSVERZEICHNIS
CHAPTER 1:THE EFFECT OF UNHEALTHY LIFESTYLE ON BRAIN METABOLISM AND
FUNCTION
CHAPTER 2: THEEFFECT OF METABOLIC SYNDROME ON THE BRAIN
CHAPTER 3: THE ASSOCIATION OF ESSENTIAL FATTY ACID METABOLISM IN THE
PATHOGENESIS OF METABOLIC SYNDROME AND NEUROLOGICAL DISORDERS
CHAPTER 4: CONTRIBUTION OF LIPID MEDIATORS TO THE PATHOGENESIS OF
METABOLIC SYNDROME AND NEUROLOGICAL DISORDERS
CHAPTER 5: MOLECULAR ASPECTS OF OBESITY AND INSULIN RESISTANCE IN
METABOLIC SYNDROME AND NEUROLOGICAL DISORDERS
CHAPTER 6: DIETARY INTERVENTIONS OF METABOLIC SYNDROME AND NEUROLOGICAL
DISORDERS
CHAPTER 7: SIGNAL TRANSDUCTION PROCESSES AND METABOLIC LINK AMONG
METABOLIC SYNDROME AND STROKE
CHAPTER 8: SIGNAL TRANSDUCTION PROCESSES AND METABOLIC LINK AMONG
METABOLIC SYNDROME AND ALZHEIMER’S DISEASE
CHAPTER 9: SIGNAL TRANSDUCTION PROCESSES AND METABOLIC LINK AMONG
METABOLIC SYNDROME AND DEPRESSION
CHAPTER 10: FUTURE RESEARCHPERSPECTIVES
DIESES SCHRIFTSTUECK WURDE MASCHINELL ERZEUGT.
METABOLIC SYNDROME
/ FAROOQUI, AKHLAQ A.
: 2013
ABSTRACT / INHALTSTEXT
THE METABOLIC SYNDROME IS A CLUSTER OF COMMON PATHOLOGIES: ABDOMINAL
OBESITY LINKED TO AN EXCESS OF VISCERAL FAT, INSULIN RESISTANCE,
DYSLIPIDEMIA AND HYPERTENSION. AT THE MOLECULAR LEVEL, METABOLIC
SYNDROME IS ACCOMPANIED NOT ONLY BY DYSREGULATION IN THE EXPRESSION OF
ADIPOKINES, CYTOKINES, AND CHEMOKINES BUT ALSO BY ALTERATIONS IN INSULIN
AND LEPTIN SIGNALING, OXIDATIVE STRESS, AND CHRONIC LOW GRADE
INFLAMMATION. THESE CHANGES AFFECT IMMUNE RESPONSES AND MEDIATE CHRONIC
INFLAMMATION LEADING TO ALTERATIONS IN THE HYPOTHALAMIC
‘BODYWEIGHT/APPETITE/SATIETY SET POINT’. IT IS BECOMING INCREASINGLY
EVIDENT THAT METABOLIC SYNDROME IS A RISK FACTOR FOR NEUROLOGICAL
DISORDERS SUCH AS STROKE, DEPRESSION, AND ALZHEIMER DISEASE (AD). FAMILY
HISTORY, AGE, ENVIRONMENTAL AND LIFESTYLE FACTORS (DIET AND PHYSICAL
INACTIVITY, AND EXPOSURE TO TOXINS) ARE CLOSELY ASSOCIATED WITH
PREDISPOSITION FOR THE DEVELOPMENT OF METABOLIC SYNDROME AS WELL AS
NEUROLOGICAL DISORDERS.THE INCIDENCES OF STROKE ARE 2 TO 4-FOLD HIGHER
IN PATIENTS WITH METABOLIC SYNDROME AND CARDIOVASCULAR DISEASES COMPARED
TO NORMAL SUBJECTS OF THE SAME AGE. SIMILARLY, PATIENTS WITH METABOLIC
SYNDROME HAVE A 2 TO 3-FOLD INCREASED RISK FOR DEVELOPING DEMENTIA AND
AD. METABOLIC SYNDROME DOUBLES THE RISK OF DEPRESSION. THE MOLECULAR
MECHANISM UNDERLYING THE MIRROR RELATIONSHIP BETWEEN METABOLIC SYNDROME
AND NEUROLOGICAL DISORDERS IS NOT FULLY UNDERSTOOD. HOWEVER, BIOCHEMICAL
ALTERATIONS OBSERVED IN METABOLIC SYNDROME LIKE INDUCTION OF CHRONIC
INFLAMMATION AND OXIDATIVE STRESS, IMPAIRMENT OF ENDOTHELIAL CELL
FUNCTION, INDUCTION OF INSULIN AND LEPTIN RESISTANCE,
HYPERGLYCEMIA-RELATED INCREASE IN ADVANCED GLYCATION END-PRODUCTS, AND
MICRO-VASCULAR INJURY MAY REPRESENT A PATHOLOGICAL BRIDGE BETWEEN
METABOLIC SYNDROME AND NEUROLOGICAL DISORDERS.IT IS HOPED THAT METABOLIC
SYNDROME: AN IMPORTANT RISK FACTOR FOR STROKE, ALZHEIMER DISEASE, AND
DEPRESSION WILL BE USEFUL TO POSTGRADUATE STUDENTS, FACULTY, RESEARCH
SCIENTISTS, PHARMACOLOGISTS, NUTRITIONISTS, AND PHYSICIANS, WHO ARE
CURIOUS ABOUT THE MOLECULAR MECHANISMS THAT LINK METABOLIC SYNDROME WITH
STROKE, ALZHEIMER DISEASE, AND DEPRESSION
DIESES SCHRIFTSTUECK WURDE MASCHINELL ERZEUGT.
|
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| spelling | Farooqui, Akhlaq A. Verfasser (DE-588)138987955 aut Metabolic syndrome an important risk factor for stroke, Alzheimer disease, and depression Akhlaq A. Farooqui New York, NY Springer 2013 1 Online-Ressource txt rdacontent c rdamedia cr rdacarrier Medicine Neurosciences Neurochemistry Neurology Biomedicine Metabolic syndrome Medizin https://doi.org/10.1007/978-1-4614-7318-3 Verlag Volltext Springer Fremddatenuebernahme application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=026092549&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis Springer Fremddatenuebernahme application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=026092549&sequence=000003&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA Abstract |
| spellingShingle | Farooqui, Akhlaq A. Metabolic syndrome an important risk factor for stroke, Alzheimer disease, and depression Medicine Neurosciences Neurochemistry Neurology Biomedicine Metabolic syndrome Medizin |
| title | Metabolic syndrome an important risk factor for stroke, Alzheimer disease, and depression |
| title_auth | Metabolic syndrome an important risk factor for stroke, Alzheimer disease, and depression |
| title_exact_search | Metabolic syndrome an important risk factor for stroke, Alzheimer disease, and depression |
| title_full | Metabolic syndrome an important risk factor for stroke, Alzheimer disease, and depression Akhlaq A. Farooqui |
| title_fullStr | Metabolic syndrome an important risk factor for stroke, Alzheimer disease, and depression Akhlaq A. Farooqui |
| title_full_unstemmed | Metabolic syndrome an important risk factor for stroke, Alzheimer disease, and depression Akhlaq A. Farooqui |
| title_short | Metabolic syndrome |
| title_sort | metabolic syndrome an important risk factor for stroke alzheimer disease and depression |
| title_sub | an important risk factor for stroke, Alzheimer disease, and depression |
| topic | Medicine Neurosciences Neurochemistry Neurology Biomedicine Metabolic syndrome Medizin |
| topic_facet | Medicine Neurosciences Neurochemistry Neurology Biomedicine Metabolic syndrome Medizin |
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