Peroxisome proliferator-activated receptors: discovery and recent advances
Saved in:
| Main Authors: | , |
|---|---|
| Format: | Electronic eBook |
| Language: | English |
| Published: |
Totowa, NJ
Humana Press
2013
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| Subjects: | |
| Online Access: | FAN01 UBT01 Volltext Inhaltsverzeichnis Abstract |
| Physical Description: | 1 Online-Ressource |
| ISBN: | 9781627034197 9781627034203 |
| DOI: | 10.1007/978-1-62703-420-3 |
Staff View
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Record in the Search Index
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| adam_text | PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS
/ YOUSSEF, JIHAN A.
: 2013
TABLE OF CONTENTS / INHALTSVERZEICHNIS
INTRODUCTION.-HISTORY OF PPAR DISCOVERY:PEROXISOMES
PEROXISOMAL BIOGENESIS AND DISEASES
PEROXISOME PROLIFERATION.-PEROXISOME PROLIFERATOR-ACTIVATED
RECEPTORS:CHROMOSOMAL LOCATION AND GENE POLYMORPHISM
PROTEIN STRUCTURE
PPAR LIGANDS:ENDOGENOUS LIGANDS
EXOGENOUS PPAR MODULATORS
TISSUE DISTRIBUTION AND VERSATILE FUNCTIONS OF PPARS:NEUROLOGICAL
FUNCTIONS OF PPARS.-PPARS AND THE CARDIOVASCULAR SYSTEM.-PPARS IN
PULMONARY PHYSIOLOGY AND DISEASE.-GASTROINTESTINAL ROLES OF
PPARS.-PPAR FUNCTIONS IN THE LIVER.-ROLES OF PPARS IN THE
PANCREAS.-PPARS IN THE URINARY TRACT PHYSIOLOGY AND
PATHOPHYSIOLOGY.-PPARS IN THE REPRODUCTIVE SYSTEM
BONE METABOLISM AND PPARS.-ROLES OF PPARS IN SKELETAL MUSCLE
BIOLOGY.-SKIN PPARS.-PPARS AND DRUG METABOLISM
MOLECULAR ASPECTS OF PPAR ACTIONS:POSTTRANSLATIONAL CONTROL OF
PPARS.-MECHANISM OF ACTION.-ANIMAL MODELS IN PPAR RESEARCH.-SAFETY
OF PPAR AGONISTS.-THE FUTURE OF PPAR RESEARCH
DIESES SCHRIFTSTUECK WURDE MASCHINELL ERZEUGT.
PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS
/ YOUSSEF, JIHAN A.
: 2013
ABSTRACT / INHALTSTEXT
ALL THREE PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR (PPAR) SUBTYPES
SHARE A HIGH DEGREE OF STRUCTURAL HOMOLOGY WHILE EXHIBITING DIFFERENCES
IN FUNCTION, TISSUE DISTRIBUTION, AND LIGAND SPECIFICITY. IN PEROXISOME
PROLIFERATOR-ACTIVATED RECEPTORS: DISCOVERY AND RECENT ADVANCES, THE
AUTHORS TRACE THE HISTORY OF PPAR DISCOVERY AND DETAIL THE RECEPTOR
STRUCTURE AND ITS POSTTRANSLATIONAL MODIFICATIONS. FURTHERMORE,
ENDOGENOUS LIGANDS AS WELL AS VARIOUS CLASSES OF EXOGENOUS LIGANDS,
SUBTYPE-SELECTIVE, DUAL AND PAN AGONISTS AS WELL AS ANTAGONISTS, ARE
DISCUSSED. IN ADDITION, THE TISSUE DISTRIBUTION AND VERSATILE FUNCTIONS
OF PPAR SUBTYPES IN MAJOR ORGANS ARE DESCRIBED. AS PPARS PLAY
CRITICAL ROLES AS REGULATORS OF NUMEROUS PHYSIOLOGICAL AS WELL AS
PATHOPHYSIOLOGICAL PATHWAYS, PEROXISOME PROLIFERATOR-ACTIVATED
RECEPTORS: DISCOVERY AND RECENT ADVANCES AIMS TO HELP RESEARCHERS TO
DEVELOP SAFER AND MORE EFFECTIVE PPAR MODULATORS AS THERAPEUTIC AGENTS
TO TREAT A MYRIAD OF DISEASES AND CONDITIONS
DIESES SCHRIFTSTUECK WURDE MASCHINELL ERZEUGT.
|
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| spelling | Youssef, Jihan A. Verfasser aut Peroxisome proliferator-activated receptors discovery and recent advances Jihan A. Youssef ; Mostafa Z. Badr Totowa, NJ Humana Press 2013 1 Online-Ressource txt rdacontent c rdamedia cr rdacarrier Biowissenschaften Life sciences Biochemistry Cell receptors Badr, Mostafa Z. Verfasser aut https://doi.org/10.1007/978-1-62703-420-3 Verlag Volltext Springer Fremddatenuebernahme application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=026014373&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis Springer Fremddatenuebernahme application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=026014373&sequence=000003&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA Abstract |
| spellingShingle | Youssef, Jihan A. Badr, Mostafa Z. Peroxisome proliferator-activated receptors discovery and recent advances Biowissenschaften Life sciences Biochemistry Cell receptors |
| title | Peroxisome proliferator-activated receptors discovery and recent advances |
| title_auth | Peroxisome proliferator-activated receptors discovery and recent advances |
| title_exact_search | Peroxisome proliferator-activated receptors discovery and recent advances |
| title_full | Peroxisome proliferator-activated receptors discovery and recent advances Jihan A. Youssef ; Mostafa Z. Badr |
| title_fullStr | Peroxisome proliferator-activated receptors discovery and recent advances Jihan A. Youssef ; Mostafa Z. Badr |
| title_full_unstemmed | Peroxisome proliferator-activated receptors discovery and recent advances Jihan A. Youssef ; Mostafa Z. Badr |
| title_short | Peroxisome proliferator-activated receptors |
| title_sort | peroxisome proliferator activated receptors discovery and recent advances |
| title_sub | discovery and recent advances |
| topic | Biowissenschaften Life sciences Biochemistry Cell receptors |
| topic_facet | Biowissenschaften Life sciences Biochemistry Cell receptors |
| url | https://doi.org/10.1007/978-1-62703-420-3 http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=026014373&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=026014373&sequence=000003&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA |
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