Holdings: Central nervous system metastasis, the biological basis and clinical considerations

Central nervous system metastasis, the biological basis and clinical considerations:

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Bibliographic Details
Format:	Book
Language:	English
Published:	Dordrecht [u.a.] Springer 2012
Series:	Cancer metastasis 18
Subjects:	Medizin Medicine Oncology Neurosciences Radiology, Medical Metastase Hirntumor Zentralnervensystem Aufsatzsammlung
Online Access:	Klappentext Inhaltsverzeichnis
Physical Description:	XI, 226 S. Ill., graph. Darst.
ISBN:	9400752903 9789400752900

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MARC


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adam_text	Cancer Metastasis - Biology and Treatment 18 Diane Palmieri Editor Central Nervous System Metastasis, the Biological Basis and Clinical Considerations This volume covers what is known regarding the natural history, basic biology, and clinical aspects, including imaging and treatment, ol ( NS metastasis. Three chapters cover the biology ol the brain and brain métastases: molecular biology, includes what is known about specific genes proteins involved in the process ol metastasis and model systems to study brain metastasis; brain microenvironment, locuses on the resident cells ol the microenvironment and their role in CNS metastasis; and the blood-brain barrier, includes a discussion ol permeability with respect to brain métastases. A discussion ol experimental imaging covers both the biology ol brain metastasis from an imaging perspective and the use oí imaging techniques to study brain métastases. lhe three clinical chapters discuss treatment options o ť surgery, chemotherapy, and radiation. The potential lor novel targeted therapies is also addressed. Because ol the uniqueness ot the disease, leptomeningeal metastasis is discussed separately. The last chapter is devoted to quality of lite issues associated with CNS metastasis. Contents 1 An Introduction to Brain Metastasis ..................................................... 1 Diane Palmieri 2 The Molecular Biology of Brain Metastasis ......................................... 15 Stephan Woditschka, Brunilde Gril. Lynda M. Evans. L. Tiffany Reed, and Patricia S. Stecg 3 The Brain Microenvironment................................................................ 43 Mami Noda 4 Vascular Permeability Within Brain Métastases ................................. 55 Chris E. Adkins. Rajendar K. Mittapalli. Касі A. Bohn. Amit Bansal. Vinay K. Venishctty. and Paul R. Lockman 5 Imaging Experimental Brain Métastases .............................................. 69 Amanda M. Hamilton and Paula J. Foster 6 Possibilities of Targeted Therapies for Brain Metastasis .................... 87 Frank Winkler 7 Surgery for Brain Metastasis ................................................................. 109 Douglas L. Stofko. Robert J. Weil, and Steven A. Toms 8 Is There a Role for Systemic Chemotherapy in the Treatment of Brain Métastases? ................................................. 133 Marc C. Chamberlain 9 Radiation Therapy of CNS Métastases ................................................. 153 DeeDee Smart vi Contents 10 Leptomeningeal Metastasis .................................................................... 187 Priscilla К. Brastianos, Charilaos H. Brastianos, and April F. Eichler 11 Quality of Life with CNS Metastasis..................................................... 201 Lauren A. Chandler and Kathleen L. Fuchs Index ................................................................................................................. 221
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discipline	Medizin
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isbn	9400752903 9789400752900
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physical	XI, 226 S. Ill., graph. Darst.
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series	Cancer metastasis
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spelling	Central nervous system metastasis, the biological basis and clinical considerations Diane Palmieri, ed. Dordrecht [u.a.] Springer 2012 XI, 226 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Cancer metastasis 18 Medizin Medicine Oncology Neurosciences Radiology, Medical Metastase (DE-588)4125915-4 gnd rswk-swf Hirntumor (DE-588)4072521-2 gnd rswk-swf Zentralnervensystem (DE-588)4067637-7 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content Hirntumor (DE-588)4072521-2 s Zentralnervensystem (DE-588)4067637-7 s Metastase (DE-588)4125915-4 s DE-604 Palmieri, Diane Sonstige oth Erscheint auch als Online-Ausgabe 978-94-007-5291-7 Cancer metastasis 18 (DE-604)BV013564604 18 Digitalisierung UB Regensburg application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=025969160&sequence=000003&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Klappentext Digitalisierung UB Regensburg application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=025969160&sequence=000004&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis
spellingShingle	Central nervous system metastasis, the biological basis and clinical considerations Cancer metastasis Medizin Medicine Oncology Neurosciences Radiology, Medical Metastase (DE-588)4125915-4 gnd Hirntumor (DE-588)4072521-2 gnd Zentralnervensystem (DE-588)4067637-7 gnd
subject_GND	(DE-588)4125915-4 (DE-588)4072521-2 (DE-588)4067637-7 (DE-588)4143413-4
title	Central nervous system metastasis, the biological basis and clinical considerations
title_auth	Central nervous system metastasis, the biological basis and clinical considerations
title_exact_search	Central nervous system metastasis, the biological basis and clinical considerations
title_full	Central nervous system metastasis, the biological basis and clinical considerations Diane Palmieri, ed.
title_fullStr	Central nervous system metastasis, the biological basis and clinical considerations Diane Palmieri, ed.
title_full_unstemmed	Central nervous system metastasis, the biological basis and clinical considerations Diane Palmieri, ed.
title_short	Central nervous system metastasis, the biological basis and clinical considerations
title_sort	central nervous system metastasis the biological basis and clinical considerations
topic	Medizin Medicine Oncology Neurosciences Radiology, Medical Metastase (DE-588)4125915-4 gnd Hirntumor (DE-588)4072521-2 gnd Zentralnervensystem (DE-588)4067637-7 gnd
topic_facet	Medizin Medicine Oncology Neurosciences Radiology, Medical Metastase Hirntumor Zentralnervensystem Aufsatzsammlung
url	http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=025969160&sequence=000003&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=025969160&sequence=000004&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA
volume_link	(DE-604)BV013564604
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