Collaboration and innovation in the pharmaceutical industry:
Gespeichert in:
| 1. Verfasser: | |
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| Format: | Abschlussarbeit Buch |
| Sprache: | English |
| Veröffentlicht: |
2012
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| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | XIV, 187 Bl. graph. Darst. 30 cm |
Internformat
MARC
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Datensatz im Suchindex
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|---|---|
| adam_text | IMAGE 1
C O N T E N T S
ACKNOWLEDGMENTS I I
C O N T E N T S I I I
LIST O F TABLES V I
LIST O F F I G U R E S V I I
LIST O F A B B R E V I A T I O N S V I I I
G E R M A N S U M M E R Y / D E U T S C H E Z U S A M M E N F A S S U N
G I X
1 I N T R O D U C T I O N 1
1.1 RELEVANCE OF PHARMACEUTICAL INNOVATION 1
1.2 CHANGING KNOWLEDGE BASES AND COLLABORATION PATTERNS 3
1.2.1 EARLY PHARMACEUTICAL RESEARCH 3
1.2.2 RANDOM SCREENING 5
1.2.3 GUIDED RESEARCH 7
1.2.4 T H E ADVENT OF BIOTECHNOLOGY 9
1.2.5 T H E EMERGENCE OF COLLABORATION NETWORKS 12
1.3 THESIS STRUCTURE AND RESEARCH QUESTIONS 15
1.3.1 THESIS STRUCTURE 15
1.3.2 INTERNATIONAL RESEARCH NETWORKS IN PHARMACEUTICALS: STRUCTURE AND
DYNAMICS 17
1.3.3 COLLABORATION IN PHARMACEUTICAL RESEARCH: EXPLORATION OF
COUNTRYLEVEL DETERMINANTS 19
1.3.4 DETERMINANTS OF PHARMACEUTICAL INNOVATION: T H E ROLE OF TECH
NOLOGICAL OPPORTUNITIES REVISITED 20
1.3.5 RESEARCH NETWORK POSITION AND INNOVATIVE PERFORMANCE: EVI DENCE
FROM THE PHARMACEUTICAL INDUSTRY 22
2 INTERNATIONAL R E S E A R C H N E T W O R K S I N P H A R M A C E U T
I C A L S : S T R U C T U R E A N D D Y N A M I C S 2 5
2.1 INTRODUCTION 25
2.2 RELATED LITERATURE 27
2.2.1 RESEARCH NETWORKS 27
2.2.2 NETWORK DYNAMICS 29
2.3 D A T A AND RESEARCH METHODOLOGY 33
2.3.1 SOCIAL NETWORK ANALYSIS 33
2.3.2 NETWORK REGRESSIONS 38
III
HTTP://D-NB.INFO/1031695400
IMAGE 2
2.3.3 D A T A 10
2.4 INTERNATIONAL RESEARCH NETWORKS 42
2.4.1 NETWORK DESCRIPTIVES AND VISUALIZATIONS 42
2.4.2 ENTRY AND EXIT 51
2.5 EMPIRICAL RESULTS NETWORK REGRESSIONS 52
2.5.1 VARIABLES 52
2.5.2 REGRESSION RESULTS 54
2.6 CONCLUSION 56
3 C O L L A B O R A T I O N I N P H A R M A C E U T I C A L RESEARCH: E
X P L O R A T I O N O F C O U N T R Y LEVEL D E T E R M I N A N T S 5 9
3.1 INTRODUCTION 59
3.2 RELATED LITERATURE 61
3.2.1 RESEARCH COLLABORATION IN THE PHARMACEUTICAL INDUSTRY 61
3.2.2 DETERMINANTS OF COLLABORATION 62
3.3 D A T A AND RESEARCH METHODOLOGY 65
3.3.1 GRAVITY MODEL 65
3.3.2 DATA 68
3.4 EMPIRICAL RESULTS GRAVITY REGRESSION MODEL 71
3.4.1 VARIABLES AND DESCRIPTIVES 71
3.4.2 REGRESSION RESULTS 74
3.5 CONCLUSION 81
4 D E T E R M I N A N T S O F P H A R M A C E U T I C A L INNOVATION: T
H E R O L E O F TECHNOLOG ICAL O P P O R T U N I T I E S R E V I S I T
E D 8 3
4.1 INTRODUCTION 83
4.2 RELATED LITERATURE 85
4.2.1 DEMAND AND INNOVATION 85
4.2.2 TECHNOLOGICAL OPPORTUNITIES ARID INNOVATION 88
4.3 EMPIRICAL STRATEGY 90
4.4 D A T A AND VARIABLE CONSTRUCTION 92
4.4.1 PHARMACEUTICAL INNOVATION 92
4.4.2 MARKET SIZE 93
4.4.3 TECHNOLOGICAL OPPORTUNITIES 95
4.4.4 REGULATORY STRINGENCY 96
4.4.5 PRE-SAMPLE VARIABLES 97
4.5 EMPIRICAL RESULTS 97
4.5.1 DETERMINANTS OF PHARMACEUTICAL INNOVATION 97
4.5.2 .TIME STRUCTURE 99
4.5.3 ROBUSTNESS CHECKS 102
4.5.4 REVERSE CAUSALITY 106
4.6 CONCLUSION 106
5 R E S E A R C H N E T W O R K P O S I T I O N A N D I N N O V A T I V
E PERFORMANCE: E V I D E N C E F R O M T H E P H A R M A C E U T I C A L
I N D U S T R Y 109
5.1 INTRODUCTION 109
5.2 RELATED LITERATURE I L L
5.2.1 COLLABORATION IN THE PHARMACEUTICAL INDUSTRY I L L
5.2.2 COLLABORATION AND INNOVATIVE PERFORMANCE 113
IV
IMAGE 3
5.2.3 NETWORK POSITION AND INNOVATIVE PERFORMANCE 114
5.3 D A T A AND EMPIRICAL STRATEGY 116
5.3.1 EMPIRICAL STRATEGY 110
5.3.2 D A T A 117
5.4 DESCRIPTION AND VISUALIZATIONS OF CANCER RESEARCH NETWORKS 119
5.5 EMPIRICAL RESULTS 121
5.5.1 VARIABLES AND DESCRIPTIVES -121
5.5.2 RESULTS CONCERNING COLLABORATION PARTNERS 126
5.5.3 RESULTS CONCERNING NETWORK POSITION 130
5.6 CONCLUSION 131
6 C O N C L U S I O N 135
6.1 MAIN RESULTS 135
6.2 IMPLICATIONS ARID FURTHER PERSPECTIVES 137
A A P P E N D I X 1 4 1
A . L T H E PHARMACEUTICAL INNOVATION AND APPROVAL PROCESS 141
A.2 PHARMACEUTICAL INNOVATION AND P A T E N T PROTECTION 143
A.3 APPENDICES CHAPTER 2 146
A.3.1 LIST OF THERAPEUTIC AREAS AND DESCRIPTION OF VARIABLES 146
A.3.2 NETWORK CORRELATIONS 147
A.4 APPENDICES CHAPTER 3 148
A.4.1 LIST OF THERAPEUTIC AREAS AND DESCRIPTION OF VARIABLES 148
A.4.2 DESCRIPTIVES, CORRELATIONS, AND ADDITIONAL REGRESSIONS 149
A.5 APPENDICES CHAPTER 4 154
A.5.1 DESCRIPTIVE STATISTICS 154
A.5.2 ADDITIONAL RESULTS 155
A.6 APPENDICES CHAPTER 5 156
A.6.1 MEDICAL INDICATIONS 156
A.6.2 VARIABLES AND CORRELATIONS 157
B I B L I O G R A P H Y 159
ERKLARUNG GEINAB D E R P R O M O T I O N S O R D I I U N G 1 8 4
C U R R I C U L U M V I T A E 185
V
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| spelling | Rake, Bastian 1983- Verfasser (DE-588)1035572885 aut Collaboration and innovation in the pharmaceutical industry von: Bastian Rake 2012 XIV, 187 Bl. graph. Darst. 30 cm txt rdacontent n rdamedia nc rdacarrier Jena, Univ., Diss., 2012 Forschungskooperation (DE-588)4236001-8 gnd rswk-swf Pharmazeutische Industrie (DE-588)4045696-1 gnd rswk-swf Innovation (DE-588)4027089-0 gnd rswk-swf (DE-588)4113937-9 Hochschulschrift gnd-content Pharmazeutische Industrie (DE-588)4045696-1 s Innovation (DE-588)4027089-0 s Forschungskooperation (DE-588)4236001-8 s DE-604 DNB Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=025951236&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Rake, Bastian 1983- Collaboration and innovation in the pharmaceutical industry Forschungskooperation (DE-588)4236001-8 gnd Pharmazeutische Industrie (DE-588)4045696-1 gnd Innovation (DE-588)4027089-0 gnd |
| subject_GND | (DE-588)4236001-8 (DE-588)4045696-1 (DE-588)4027089-0 (DE-588)4113937-9 |
| title | Collaboration and innovation in the pharmaceutical industry |
| title_auth | Collaboration and innovation in the pharmaceutical industry |
| title_exact_search | Collaboration and innovation in the pharmaceutical industry |
| title_full | Collaboration and innovation in the pharmaceutical industry von: Bastian Rake |
| title_fullStr | Collaboration and innovation in the pharmaceutical industry von: Bastian Rake |
| title_full_unstemmed | Collaboration and innovation in the pharmaceutical industry von: Bastian Rake |
| title_short | Collaboration and innovation in the pharmaceutical industry |
| title_sort | collaboration and innovation in the pharmaceutical industry |
| topic | Forschungskooperation (DE-588)4236001-8 gnd Pharmazeutische Industrie (DE-588)4045696-1 gnd Innovation (DE-588)4027089-0 gnd |
| topic_facet | Forschungskooperation Pharmazeutische Industrie Innovation Hochschulschrift |
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