Holdings: Protein-ligand interactions

Protein-ligand interactions: methods and applications

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Bibliographic Details
Format:	Book
Language:	English
Published:	New York [u.a.] Humana Press 2013
Edition:	2. ed.
Series:	Methods in molecular biology 1008
Subjects:	Molekularbiologische Methode Ligand > Biochemie Wechselwirkung Proteine Aufsatzsammlung
Online Access:	Inhaltsverzeichnis
Physical Description:	X, 530 S. Ill., graph. Darst.

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MARC


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adam_text	Contents Preface. .................................................................... -ρ Contributors ............................................................... ix Рант і Introduction and Overview 1 Protein-Ligand Interactions: Fundamentals .............................. 3 Mark A. Williams 2 Protein Sample Characterization ........................................ 35 Tina Daviter and Rémi Frenzes 3 Measurement of Protein-Ligand Complex Formation ..................... 63 Peter N. Lowe, Сага К. Vaußhan, and Tina Daviter Part II Quantitation of Thermodynamics and Kinetics 4 Isothermal Titration Calorimetry for Studying Protem-Ligand Interactions ............................................ 103 Luminiţa Damian 5 Rapid Mixing Kinetic Techniques ....................................... 119 Stephen JR.. Martin and Maria J. Schilstra 6 Protein-Ligand Interactions Using SPR Systems .......................... 139 Asa Fruiteli, Lena Vinterback, and Hans Sjöbom Part III Spectroscopic Methods 7 Fluorescence Techniques in Analysis of Protein-Ligand Interactions ......... 169 Gabor Mocz a-nd Justin A. Ross 8 Circular and Lmear Dichroism Spectroscopy for the Study of Protein-Ligand Interactions .......................................... 211 Tin» Daviter, Nikola. Chmel, and Alison Rodger 9 Analyzing Protein-Ligand Interactions by Dynamic NMR Spectroscopy .................................................... 243 Anthony Mittermaier and Erick Meneses 10 Studying Metal Ion-Protein Interactions: Electronic Absorption, Circular Dichroism, and Electron Paramagnetic Resonance ................. 267 Liliana Quintanar and Lina Rivillas-Acevedo 11 Monitoring Protein-Ligand Interactions by Time-Resolved FTIR Difference Spectroscopy .......................................... 299 Carsten Kottinß and Klaus Gerwert VII Contents Part IV Ligan d Discovery 12 Biophysical Methods in Drug Discovery from Small Molecule to Pharmaceutical ..................................................... 327 Geoffrey Holdgate, Stefan Geschwindner, Alex Breeze, Gareth Davies, Nicola Colclough, David Temesi, and Lara Ward 13 Biophysical Screening for the Discovery of Small Molecule Ligands ......... 357 Alessio Ciulii 14 Screening Protein-Small Molecule Interactions by NMR ................... 389 Ben Davis Part V Molecules in Native Environments 15 Model Membrane Systems ............................................. 417 Heiko Keller, Remigiusz Worch, and Petra Schwüle 16 Quantitative Fluorescence Co-localization to Study Protein-Receptor Complexes ........................................... 439 Shanica N. Pompey, Peter Michaely, and Katherine Luby-Phelps Part VI Structural and Computational Methods 17 Studying Protein-Ligand Interactions Using Х -Ray Crystallography ......... 457 Andrew P. Turnbull and Paul Emsley 18 Molecular Fields in Ligand Discovery .................................... 479 Paul J . Gane and A.W. Edith Chan 19 Structure-Based Virtual Screening for Novel Ligands ...................... 501 William R. Pitt, Mark D. Calmiano, Boris Kroeplien, Richard D. Taylor, James P. Turner, and Michael A. King Index ..................................................................... 521
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discipline	Biologie
edition	2. ed.
format	Book
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indexdate	2024-07-10T00:33:59Z
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language	English
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series	Methods in molecular biology
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spelling	Protein-ligand interactions methods and applications ed. by Mark A. Williams ... 2. ed. New York [u.a.] Humana Press 2013 X, 530 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Methods in molecular biology 1008 Springer protocols Molekularbiologische Methode (DE-588)7650063-9 gnd rswk-swf Ligand Biochemie (DE-588)4606532-5 gnd rswk-swf Wechselwirkung (DE-588)4064937-4 gnd rswk-swf Proteine (DE-588)4076388-2 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content Proteine (DE-588)4076388-2 s Ligand Biochemie (DE-588)4606532-5 s Wechselwirkung (DE-588)4064937-4 s Molekularbiologische Methode (DE-588)7650063-9 s b DE-604 Williams, Mark A. 1951- Sonstige (DE-588)172984386 oth Methods in molecular biology 1008 (DE-604)BV035362695 1008 Digitalisierung UB Regensburg application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=025773242&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis
spellingShingle	Protein-ligand interactions methods and applications Methods in molecular biology Molekularbiologische Methode (DE-588)7650063-9 gnd Ligand Biochemie (DE-588)4606532-5 gnd Wechselwirkung (DE-588)4064937-4 gnd Proteine (DE-588)4076388-2 gnd
subject_GND	(DE-588)7650063-9 (DE-588)4606532-5 (DE-588)4064937-4 (DE-588)4076388-2 (DE-588)4143413-4
title	Protein-ligand interactions methods and applications
title_auth	Protein-ligand interactions methods and applications
title_exact_search	Protein-ligand interactions methods and applications
title_full	Protein-ligand interactions methods and applications ed. by Mark A. Williams ...
title_fullStr	Protein-ligand interactions methods and applications ed. by Mark A. Williams ...
title_full_unstemmed	Protein-ligand interactions methods and applications ed. by Mark A. Williams ...
title_short	Protein-ligand interactions
title_sort	protein ligand interactions methods and applications
title_sub	methods and applications
topic	Molekularbiologische Methode (DE-588)7650063-9 gnd Ligand Biochemie (DE-588)4606532-5 gnd Wechselwirkung (DE-588)4064937-4 gnd Proteine (DE-588)4076388-2 gnd
topic_facet	Molekularbiologische Methode Ligand Biochemie Wechselwirkung Proteine Aufsatzsammlung
url	http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=025773242&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA
volume_link	(DE-604)BV035362695
work_keys_str_mv	AT williamsmarka proteinligandinteractionsmethodsandapplications

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