Coarse-Grained Modelling of DNA and DNA Self-Assembly:
Saved in:
| Format: | Electronic eBook |
|---|---|
| Language: | English |
| Published: |
Berlin, Heidelberg
Springer Berlin Heidelberg
2012
|
| Series: | Springer Theses, Recognizing Outstanding Ph.D. Research
|
| Subjects: | |
| Online Access: | TUM01 UBT01 Volltext |
| Item Description: | A Novel DNA Model -- Methods -- Finite Size Effects -- Structural and Mechanical Properties of Model DNA -- Thermodynamic Properties of Model DNA -- Modelling DNA Tweezers -- Modelling a DNA Walker This thesis presents a novel coarse-grained model of DNA, in which bases are represented as rigid nucleotides. The model is shown to quantitatively reproduce many phenomena, including elastic properties of the double-stranded state, hairpin formation in single strands and hybridization of pairs of strands to form duplexes, the first time such a wide range of properties has been captured by a coarse-grained model. The scope and potential of the model is demonstrated by simulating DNA tweezers, an iconic nanodevice, and a two-footed DNA walker — the first time that coarse-grained modelling has been applied to dynamic DNA nanotechnology |
| Physical Description: | 1 Online-Ressource |
| ISBN: | 9783642305177 |
| DOI: | 10.1007/978-3-642-30517-7 |
Staff View
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| 500 | |a This thesis presents a novel coarse-grained model of DNA, in which bases are represented as rigid nucleotides. The model is shown to quantitatively reproduce many phenomena, including elastic properties of the double-stranded state, hairpin formation in single strands and hybridization of pairs of strands to form duplexes, the first time such a wide range of properties has been captured by a coarse-grained model. The scope and potential of the model is demonstrated by simulating DNA tweezers, an iconic nanodevice, and a two-footed DNA walker — the first time that coarse-grained modelling has been applied to dynamic DNA nanotechnology | ||
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| id | DE-604.BV040751351 |
| illustrated | Not Illustrated |
| indexdate | 2024-07-10T00:33:09Z |
| institution | BVB |
| isbn | 9783642305177 |
| language | English |
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| physical | 1 Online-Ressource |
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| publishDate | 2012 |
| publishDateSearch | 2012 |
| publishDateSort | 2012 |
| publisher | Springer Berlin Heidelberg |
| record_format | marc |
| series2 | Springer Theses, Recognizing Outstanding Ph.D. Research |
| spelling | Coarse-Grained Modelling of DNA and DNA Self-Assembly by Thomas E. Ouldridge Berlin, Heidelberg Springer Berlin Heidelberg 2012 1 Online-Ressource txt rdacontent c rdamedia cr rdacarrier Springer Theses, Recognizing Outstanding Ph.D. Research A Novel DNA Model -- Methods -- Finite Size Effects -- Structural and Mechanical Properties of Model DNA -- Thermodynamic Properties of Model DNA -- Modelling DNA Tweezers -- Modelling a DNA Walker This thesis presents a novel coarse-grained model of DNA, in which bases are represented as rigid nucleotides. The model is shown to quantitatively reproduce many phenomena, including elastic properties of the double-stranded state, hairpin formation in single strands and hybridization of pairs of strands to form duplexes, the first time such a wide range of properties has been captured by a coarse-grained model. The scope and potential of the model is demonstrated by simulating DNA tweezers, an iconic nanodevice, and a two-footed DNA walker — the first time that coarse-grained modelling has been applied to dynamic DNA nanotechnology Physics Polymers Nanotechnology Biophysics and Biological Physics Polymer Sciences Statistical Physics, Dynamical Systems and Complexity Soft and Granular Matter, Complex Fluids and Microfluidics Ouldridge, Thomas E. Sonstige oth https://doi.org/10.1007/978-3-642-30517-7 Verlag Volltext |
| spellingShingle | Coarse-Grained Modelling of DNA and DNA Self-Assembly Physics Polymers Nanotechnology Biophysics and Biological Physics Polymer Sciences Statistical Physics, Dynamical Systems and Complexity Soft and Granular Matter, Complex Fluids and Microfluidics |
| title | Coarse-Grained Modelling of DNA and DNA Self-Assembly |
| title_auth | Coarse-Grained Modelling of DNA and DNA Self-Assembly |
| title_exact_search | Coarse-Grained Modelling of DNA and DNA Self-Assembly |
| title_full | Coarse-Grained Modelling of DNA and DNA Self-Assembly by Thomas E. Ouldridge |
| title_fullStr | Coarse-Grained Modelling of DNA and DNA Self-Assembly by Thomas E. Ouldridge |
| title_full_unstemmed | Coarse-Grained Modelling of DNA and DNA Self-Assembly by Thomas E. Ouldridge |
| title_short | Coarse-Grained Modelling of DNA and DNA Self-Assembly |
| title_sort | coarse grained modelling of dna and dna self assembly |
| topic | Physics Polymers Nanotechnology Biophysics and Biological Physics Polymer Sciences Statistical Physics, Dynamical Systems and Complexity Soft and Granular Matter, Complex Fluids and Microfluidics |
| topic_facet | Physics Polymers Nanotechnology Biophysics and Biological Physics Polymer Sciences Statistical Physics, Dynamical Systems and Complexity Soft and Granular Matter, Complex Fluids and Microfluidics |
| url | https://doi.org/10.1007/978-3-642-30517-7 |
| work_keys_str_mv | AT ouldridgethomase coarsegrainedmodellingofdnaanddnaselfassembly |