Tissue Functioning and Remodeling in the Circulatory and Ventilatory Systems:
Gespeichert in:
| 1. Verfasser: | |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
New York, NY [u.a.]
Springer
2013
|
| Schriftenreihe: | Biomathematical and Biomechanical Modeling of the Circulatory and Ventilatory Systems
5 |
| Schlagworte: | |
| Online-Zugang: | TUM01 UBT01 Volltext Inhaltsverzeichnis Abstract |
| Beschreibung: | The volumes in this authoritative series present a multidisciplinary approach to modeling and simulation of flows in the cardiovascular and ventilatory systems, especially multiscale modeling and coupled simulations. Volume 5 is devoted to cells, tissues, and organs of the cardiovascular and ventilatory systems with an emphasis on mechanotransduction-based regulation of flow. The blood vessel wall is a living tissue that quickly reacts to loads applied on it by the flowing blood. In any segment of a blood vessel, the endothelial and smooth muscle cells can sense unusual time variations in small-magnitude wall shear stress and large-amplitude wall stretch generated by abnormal hemodynamic stresses. These cells respond with a short-time scale (from seconds to hours) to adapt the vessel caliber. Since such adaptive cell activities can be described using mathematical models, a key objective of this volume is to identify the mesoscopic agents and nanoscopic mediators required to derive adequate mathematical models. The resulting biomathematical models and corresponding simulation software can be incorporated into platforms developed in virtual physiology for improved understanding and training.Reviews structure and function of major constituents of the circulatory and respiratory apparatusDescribes major cellular processes involved in signaling, interactions, and adaptive responses of physiological conduits. Integrates biology, chemistry, and physics for the multidisciplinary exploration and modeling of physiological flows. Focuses on mechanotransduction-induced regulation |
| Beschreibung: | 1 Online-Ressource |
| ISBN: | 9781461459668 |
| DOI: | 10.1007/978-1-4614-5966-8 |
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Datensatz im Suchindex
| _version_ | 1804150074433863680 |
|---|---|
| adam_text | TISSUE FUNCTIONING AND REMODELING IN THE CIRCULATORY AND VENTILATORY
SYSTEMS
/ THIRIET, MARC
: 2013
TABLE OF CONTENTS / INHALTSVERZEICHNIS
PREFACE
CHAPTER 1: BLOOD
CHAPTER 2: HEMATOPOIESIS
CHAPTER 3: BLOOD CELLS
CHAPTER 4: LYMPH DRAINAGE
CHAPTER 5: CARDIOMYOCYTES
CHAPTER 6: HEART WALL
CHAPTER 7: VESSEL WALL
CHAPTER 8: SMOOTH MYOCYTES
CHAPTER 9: VASCULAR ENDOTHELIUM
CHAPTER 10: VASCULAR GROWTH
CHAPTER 11: TISSUE DEVELOPMENT, REPAIR, AND REMODELING
CHAPTER 12: AIRWAY SURFACE LIQUID AND RESPIRATORY MUCUS
CHAPTER 13: SURFACTANT
CHAPTER 14: CONCLUSION
REFERENCES
LIST OF CURRENTLY USED PREFIXES AND SUFFIXES
LIST OF ALIASES
COMPLEMENTARY LISTS OF NOTATIONS
INDEX
DIESES SCHRIFTSTUECK WURDE MASCHINELL ERZEUGT.
TISSUE FUNCTIONING AND REMODELING IN THE CIRCULATORY AND VENTILATORY
SYSTEMS
/ THIRIET, MARC
: 2013
ABSTRACT / INHALTSTEXT
THE VOLUMES IN THIS AUTHORITATIVE SERIES PRESENT A MULTIDISCIPLINARY
APPROACH TO MODELING AND SIMULATION OF FLOWS IN THE CARDIOVASCULAR AND
VENTILATORY SYSTEMS, ESPECIALLY MULTISCALE MODELING AND COUPLED
SIMULATIONS. VOLUME 5 IS DEVOTED TO CELLS, TISSUES, AND ORGANS OF THE
CARDIOVASCULAR AND VENTILATORY SYSTEMS WITH AN EMPHASIS ON
MECHANOTRANSDUCTION-BASED REGULATION OF FLOW. THE BLOOD VESSEL WALL IS A
LIVING TISSUE THAT QUICKLY REACTS TO LOADS APPLIED ON IT BY THE FLOWING
BLOOD. IN ANY SEGMENT OF A BLOOD VESSEL, THE ENDOTHELIAL AND SMOOTH
MUSCLE CELLS CAN SENSE UNUSUAL TIME VARIATIONS IN SMALL-MAGNITUDE WALL
SHEAR STRESS AND LARGE-AMPLITUDE WALL STRETCH GENERATED BY ABNORMAL
HEMODYNAMIC STRESSES. THESE CELLS RESPOND WITH A SHORT-TIME SCALE (FROM
SECONDS TO HOURS) TO ADAPT THE VESSEL CALIBER. SINCE SUCH ADAPTIVE CELL
ACTIVITIES CAN BE DESCRIBED USING MATHEMATICAL MODELS, A KEY OBJECTIVE
OF THIS VOLUME IS TO IDENTIFY THE MESOSCOPIC AGENTS AND NANOSCOPIC
MEDIATORS REQUIRED TO DERIVE ADEQUATE MATHEMATICAL MODELS. THE
RESULTING BIOMATHEMATICAL MODELS AND CORRESPONDING SIMULATION SOFTWARE
CAN BE INCORPORATED INTO PLATFORMS DEVELOPED IN VIRTUAL PHYSIOLOGY FOR
IMPROVED UNDERSTANDING AND TRAINING. REVIEWS STRUCTURE AND FUNCTION OF
MAJOR CONSTITUENTS OF THE CIRCULATORY AND RESPIRATORY APPARATUS
DESCRIBES MAJOR CELLULAR PROCESSES INVOLVED IN SIGNALING, INTERACTIONS,
AND ADAPTIVE RESPONSES OF PHYSIOLOGICAL CONDUITS INTEGRATES BIOLOGY,
CHEMISTRY, AND PHYSICS FOR THE MULTIDISCIPLINARY EXPLORATION AND
MODELING OF PHYSIOLOGICAL FLOWS FOCUSES ON MECHANOTRANSDUCTION-INDUCED
REGULATION
DIESES SCHRIFTSTUECK WURDE MASCHINELL ERZEUGT.
|
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| series2 | Biomathematical and Biomechanical Modeling of the Circulatory and Ventilatory Systems |
| spelling | Thiriet, Marc Verfasser (DE-588)1019322721 aut Tissue Functioning and Remodeling in the Circulatory and Ventilatory Systems Marc Thiriet New York, NY [u.a.] Springer 2013 1 Online-Ressource txt rdacontent c rdamedia cr rdacarrier Biomathematical and Biomechanical Modeling of the Circulatory and Ventilatory Systems 5 The volumes in this authoritative series present a multidisciplinary approach to modeling and simulation of flows in the cardiovascular and ventilatory systems, especially multiscale modeling and coupled simulations. Volume 5 is devoted to cells, tissues, and organs of the cardiovascular and ventilatory systems with an emphasis on mechanotransduction-based regulation of flow. The blood vessel wall is a living tissue that quickly reacts to loads applied on it by the flowing blood. In any segment of a blood vessel, the endothelial and smooth muscle cells can sense unusual time variations in small-magnitude wall shear stress and large-amplitude wall stretch generated by abnormal hemodynamic stresses. These cells respond with a short-time scale (from seconds to hours) to adapt the vessel caliber. Since such adaptive cell activities can be described using mathematical models, a key objective of this volume is to identify the mesoscopic agents and nanoscopic mediators required to derive adequate mathematical models. The resulting biomathematical models and corresponding simulation software can be incorporated into platforms developed in virtual physiology for improved understanding and training.Reviews structure and function of major constituents of the circulatory and respiratory apparatusDescribes major cellular processes involved in signaling, interactions, and adaptive responses of physiological conduits. Integrates biology, chemistry, and physics for the multidisciplinary exploration and modeling of physiological flows. Focuses on mechanotransduction-induced regulation Physics Cardiology Biological models Hydraulic engineering Biomedical engineering Biophysics and Biological Physics Biomedical Engineering Mathematical and Computational Biology Systems Biology Engineering Fluid Dynamics Erscheint auch als Druckausgabe 978-1-4614-5965-1 Biomathematical and Biomechanical Modeling of the Circulatory and Ventilatory Systems 5 (DE-604)BV041546699 5 https://doi.org/10.1007/978-1-4614-5966-8 Verlag Volltext Springer Fremddatenuebernahme application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=025730931&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis Springer Fremddatenuebernahme application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=025730931&sequence=000003&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA Abstract |
| spellingShingle | Thiriet, Marc Tissue Functioning and Remodeling in the Circulatory and Ventilatory Systems Biomathematical and Biomechanical Modeling of the Circulatory and Ventilatory Systems Physics Cardiology Biological models Hydraulic engineering Biomedical engineering Biophysics and Biological Physics Biomedical Engineering Mathematical and Computational Biology Systems Biology Engineering Fluid Dynamics |
| title | Tissue Functioning and Remodeling in the Circulatory and Ventilatory Systems |
| title_auth | Tissue Functioning and Remodeling in the Circulatory and Ventilatory Systems |
| title_exact_search | Tissue Functioning and Remodeling in the Circulatory and Ventilatory Systems |
| title_full | Tissue Functioning and Remodeling in the Circulatory and Ventilatory Systems Marc Thiriet |
| title_fullStr | Tissue Functioning and Remodeling in the Circulatory and Ventilatory Systems Marc Thiriet |
| title_full_unstemmed | Tissue Functioning and Remodeling in the Circulatory and Ventilatory Systems Marc Thiriet |
| title_short | Tissue Functioning and Remodeling in the Circulatory and Ventilatory Systems |
| title_sort | tissue functioning and remodeling in the circulatory and ventilatory systems |
| topic | Physics Cardiology Biological models Hydraulic engineering Biomedical engineering Biophysics and Biological Physics Biomedical Engineering Mathematical and Computational Biology Systems Biology Engineering Fluid Dynamics |
| topic_facet | Physics Cardiology Biological models Hydraulic engineering Biomedical engineering Biophysics and Biological Physics Biomedical Engineering Mathematical and Computational Biology Systems Biology Engineering Fluid Dynamics |
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