Planar cell polarity during development:
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
Amsterdam [u.a.]
Elsevier/Acad. Press
2012
|
| Schriftenreihe: | Current topics in developmental biology
101 |
| Schlagworte: | |
| Online-Zugang: | http://scans.hebis.de/HEBCGI/show.pl?31213687_kub.html http://scans.hebis.de/HEBCGI/show.pl?31213687_aub.html http://scans.hebis.de/HEBCGI/show.pl?31213687_toc.pdf Inhaltsverzeichnis |
| Beschreibung: | Hardback. - Literaturangaben |
| Beschreibung: | XIII, 341 S. Ill. 23x15 cm |
| ISBN: | 9780123945921 0123945925 |
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Datensatz im Suchindex
| _version_ | 1804150068860682240 |
|---|---|
| adam_text | VOLUME ONE HUNDRED AND ONE
CURRENT TOPICS IN
DEVELOPMENTAL
BIOLOGY
Planar Cell Polarity During
Development
Edited by
YINGZI YANG
Bethesda, MD, USA
ELSEVIER
AMSTERDAM • BOSTON • HEIDELBERG • LONDON
NEW YORK • OXFORD • PARIS • SAN DIEGO
SAN FRANCISCO • SINGAPORE • SYDNEY • TOKYO
Acadumt Press is an imprint of Elsevier
CONTENTS
Contributors ix
Preface xi
1 The frizzled/stan Pathway and Planar Cell Polarity
in the Drosophila Wing 1
Paul N Adler
1 Introduction to Drosophila Planar Cell Polarity 2
2 The Cellular Basis for PCP 3
3 PCP Genes 9
4 What is the Basis for the Asymmetric Localization of fz/stan Pathway Proteins? 16
5 Directional Cell Nonautonomy 20
6 Downstream Effectors 22
Acknowledgments 24
References 24
2 Asymmetric Protein Localization in Planar Cell Polarity:
Mechanisms, Puzzles, and Challenges 33
Ying Peng and Jeffrey D Axelrod
1 Introduction 34
2 Revisiting the Three-Tiered Hierarchy of PCP 35
3 Asymmetric Protein Localization: A Hallmark of PCP 40
4 The Ways and Means to Planar Polarize a Cell: Mechanisms of Achieving
Asymmetry 42
Acknowledgments 50
References 50
3 Control of Cell Polarity and Asymmetric Division in C elegans 55
Hitoshi Sawa
1 Cortical Asymmetry of Wnt Signaling Components 56
2 Connecting Cell Cortex to Nuclei 58
3 Asymmetric Regulation of Transcription in Nuclei 59
4 Spindle Orientation and MTOC Positioning 61
5 Wnts Instructively Orient Polarity of the EMS and T Cells 62
6 Coordination of Spindle Orientation by MOM-2/Wnt 63
7 Coordination of Asymmetric Cell Divisions During Embryogenesis 65
vi Contents
8 Coordination of Asymmetric Cell Divisions During Postembryonic
Development 67
9 Polarity Reversal in Normal Development 69
10 Functions of PCP Components in C elegans 70
11 Summary and Perspective 72
Acknowledgments 73
References 73
4 Planar Cell Polarity in Coordinated and Directed Movements 77
Masazumi Tada and Masatake Kai
1 Introduction 78
2 Coordinated and Directed Movements During Vertebrate Gastrulation 79
3 Planar Cell Polarity Signaling in Vertebrates 84
4 PCP Regulating CE and Collective Cell Migration in Other Contexts 94
5 PCP in Mediating Collectiveness and Polarized Behaviors 98
6 Concluding Remarks 101
Acknowledgments 101
References 102
5 Planar Cell Polarity in the Inner Ear 111
Helen May-Simera and Matthew W Kelley
1 Introduction to the Inner Ear 112
2 Development of the Inner Ear 113
3 Molecular Mechanism of Planar Cell Polarity 118
4 Upstream Regulators of PCP 128
5 Cilia and Their Role in PCP 129
6 Looking Forward: PCP Signaling in the Inner Ear, Where Do We Go
from Here? 133
References 135
6 Does Planar Cell Polarity Signaling Steer Growth Cones? 141
Yimin Zou
1 Outline of Review 142
2 PCP Signaling Components Mediate Axon Guidance 142
3 Can PCP Signaling Be Used in Motile Growth Cones? 145
4 Is the Growth Cone Polarized? 147
5 Biochemistry and Cell Biology of PCP Signaling 149
6 Localization of Vangl2 Puncta on Filopodia Tips Suggests That PCP
Signaling May Steer Growth Cones 151
Contents vii
7 Are There Growth Cone-Growth Cone Interactions During
PCP-Mediated Turning? 152
8 Is This Cell Polarity-Based Signaling System a General Growth
Cone Steering Mechanism? 153
9 Summary 156
References 157
7 Celsr1-3 Cadherins in PCP and Brain Development 161
Camille Boutin, Andre M Goffinet, and Fadel Tissir
1 Celsrl —3 Expression Patterns 164
2 Celsrl: A Major Player in Vertebrate PCP 165
3 Celsr2 and 3 in Ciliogenesis 169
4 Celsrl-3 in Neuronal Migration 171
5 Celsr2 and Celsr3 in Brain Wiring 174
References 179
8 The Kidney and Planar Cell Polarity 185
Thomas J Carroll and Jing Yu
1 Introduction 186
2 Planar Cell Polarity 186
3 Kidney Development 191
4 PCP in Kidney Development 195
5 PCP and Tubular Repair 204
6 Conclusion 205
References 206
9 Dishevelled: In Vivo Roles of a Multifunctional Gene Family
During Development 213
Anthony Wynshaw-Boris
1 Canonical Wnt Pathway
2 PCP Pathway, a Noncanonical Wnt Pathway
3 Conserved Mammalian PCP Pathway
4 Dvl Genes: Crossroads of Wnt and PCP Pathways
5 Single Mutants for Dvl Genes in the Mouse: Unique Phenotypes
6 Dvll Null Mice: Social Interaction Defects
7 Dvl2 Mutant Mice: Cardiac, Neurulation, and Skeletal Defects
8 Dvl3 Mutant Mice
9 Dvl Double Mutants: Redundancy Among the Dvl Genes
10 Dvl 1/2 Double Mutants
viii Contents
11 Dvl 1/3 Double Mutants 226
12 Dvl2/3 Double Mutants 227
13 Dvll,2,3 Triple Mutants Display Defects in the Posterior Placement
of Nodal Cilia 227
14 Dvl Conditional Tagged Alleles 228
15 Dvl Transgenes Demonstrate Functional Redundancy 229
16 Dvl2 Allelic Series to Distinguish Wnt and PCP Pathway Phenotypes
In Vivo 229
17 Conclusions and Future Studies 231
References 232
10 An Expanding Role of Vang I Proteins in Embryonic
Development 237
Elena Torban, Alexandra lliescu, and Philippe Gros
1 Vangl Proteins, Neurulation, and Neural Tube Defects 238
2 Vangl Proteins, Planar Cell Polarity, and Tissue Patterning 242
3 Role of Vangl2 in Structure and Function of Ciliated Cells 248
4 Cellular and Molecular Mechanism of Action of Vangl2 in Vertebrates 252
5 Conclusions 255
Acknowledgments 255
References 256
11 Wnt Regulation of Planar Cell Polarity (PCP) 263
Bo Gao
1 Introduction 264
2 Wnt and Planar Cell Polarity 265
3 Missing Link Between Wnt and PCP 280
4 Conclusion 284
Acknowledgment 285
References 286
Index
Contents of Previous Volumes
|
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| spelling | Planar cell polarity during development ed. by Yingzi Yang Amsterdam [u.a.] Elsevier/Acad. Press 2012 XIII, 341 S. Ill. 23x15 cm txt rdacontent n rdamedia nc rdacarrier Current topics in developmental biology 101 Hardback. - Literaturangaben Polarität (DE-588)4126483-6 gnd rswk-swf Entwicklungsphysiologie (DE-588)4152449-4 gnd rswk-swf Zelle (DE-588)4067537-3 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content Entwicklungsphysiologie (DE-588)4152449-4 s Zelle (DE-588)4067537-3 s Polarität (DE-588)4126483-6 s DE-188 Yang, Yingzi 1981- Sonstige (DE-588)139812334 oth Current topics in developmental biology 101 (DE-604)BV002685390 101 X:Nielsen text/html http://scans.hebis.de/HEBCGI/show.pl?31213687_kub.html X:Nielsen text/html http://scans.hebis.de/HEBCGI/show.pl?31213687_aub.html V:DE-603;B:DE-30 application/pdf http://scans.hebis.de/HEBCGI/show.pl?31213687_toc.pdf HEBIS Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=025726233&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
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| title | Planar cell polarity during development |
| title_auth | Planar cell polarity during development |
| title_exact_search | Planar cell polarity during development |
| title_full | Planar cell polarity during development ed. by Yingzi Yang |
| title_fullStr | Planar cell polarity during development ed. by Yingzi Yang |
| title_full_unstemmed | Planar cell polarity during development ed. by Yingzi Yang |
| title_short | Planar cell polarity during development |
| title_sort | planar cell polarity during development |
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