Die Bedeutung der Gefäßheilung nach vaskulärer Intervention: = The importance of vascular healing after percutaneous interventions
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| Main Author: | |
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| Format: | Thesis Book |
| Language: | English |
| Published: |
2012
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| Subjects: | |
| Online Access: | Inhaltsverzeichnis |
| Physical Description: | 35 Bl. Ill., graph. Darst. |
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| adam_text | IMAGE 1
INHALTSVERZEICHNIS - TABLE OF CONTENTS
TABLE OF CONTENTS
1. INTRODUCTION 5
1.1 THE RELEVANCE OF DELAYED ARTERIAL HEALING IN CORONARY ARTERY DISEASE
5 1.2 THE CLINICAL PROBLEM OF LATE STENT THROMBOSIS 5
1.3 THE ROLE OF INTEGRINS IN VASCULAR HEALING 6
2. STUDY AIMS 7
3. SYNOPSIS OF ORIGINAL CONTRIBUTIONS IN RESEARCH CONTEXT 9
3.1 THE PATHOLOGY OF DRUG ELUTING STENTS IN HUMANS: DELAYED ARTERIAL
HEALING AND LATE THROMBOTIC RISK 9
3.1.1 THE FOUR HISTOPATHOLOGIC PRINCIPLES UNDERLYING DELAYED ARTERIAL
HEALING 9
3.1.2 PATHOLOGIC SUBSTRATES OF LATE STENT THROMBOSIS. STRUT COVERAGE AS
A MARKER OF ENDOTHELIALIZATION 11
3.1.3 DELAYED ARTERIAL HEALING AND INCREASED LATE STENT THROMBOSIS AT
CULPRIT SITES AFTER DRUG ELUTING STENT PLACEMENT FOR ACUTE MYOCARDIAL
INFARCTION PATIENTS: AN AUTOPSY STUDY 13
3.2 PRECLINICAL STUDIES INVESTIGATING DELAYED ARTERIAL HEALING 14
3.2.1 COMPARATOR ANALYSIS OF HEALING BETWEEN FDA-APPROVED DES PLATFORMS
IN A PRECLINICAL ANIMAL MODEL 14
3.2.2 VASCULAR HEALING IN DRUG ELUTING STENTS: DIFFERENTIAL
DRUG-ASSOCIATED RESPONSE OF LIMUS-ELUTING STENTS IN A PRECLINICAL MODEL
OF STENT IMPLANTATION 16 3.3 NOVEL STRATEGIES TO.REDUCE IN-STENT
RESTENOSIS 18
3.3.1 PIOGLITAZONE INHIBITS IN-STENT RESTENOSIS IN ATHEROSCLEROTIC
RABBITS BY TARGETING TRANSFORMING GROWTH FACTOR-BETA AND MCP-1 18
3.3.2 SITE SPECIFIC TARGETING OF NANOPARTICLE PREDNISOLONE REDUCES
IN-STENT RESTENOSIS IN A RABBIT MODEL OF ESTABLISHED ATHEROMA 20
3.3.3 COMPARATIVE ASSESSMENT O F DRUG ELUTING BALLOONS IN AN ADVANCED
MODEL OF CORONARY RESTENOSIS 22
3.4 NOVEL STRATEGIES TO FOSTER VASCULAR HEALING 24
3.4.1 POLYMER-FREE IMMOBILIZATION OF A CYCLIC RGD PEPTIDE ON A NITINOL
STENT PROMOTES INTEGRIN-DEPENDENT ENDOTHELIAL COVERAGE OF STRUT SURFACES
24
4. SUMMARY 26
5. LIST OF OWN PUBLICATIONS IN CHRONOLOGICAL ORDER 27
6. PUBLICATIONS REPRINTED IN APPENDIX 30
7. DANKSAGUNG 31
8. REFERENCES 32
4
HTTP://D-NB.INFO/1032412097
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| spelling | Joner, Michael Verfasser aut Die Bedeutung der Gefäßheilung nach vaskulärer Intervention = The importance of vascular healing after percutaneous interventions von Michael Joner The importance of vascular healing after percutaneous interventions 2012 35 Bl. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier München, Techn. Univ., Habil.-Schr., 2012 (DE-588)4113937-9 Hochschulschrift gnd-content DNB Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=025686071&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Joner, Michael Die Bedeutung der Gefäßheilung nach vaskulärer Intervention = The importance of vascular healing after percutaneous interventions |
| subject_GND | (DE-588)4113937-9 |
| title | Die Bedeutung der Gefäßheilung nach vaskulärer Intervention = The importance of vascular healing after percutaneous interventions |
| title_alt | The importance of vascular healing after percutaneous interventions |
| title_auth | Die Bedeutung der Gefäßheilung nach vaskulärer Intervention = The importance of vascular healing after percutaneous interventions |
| title_exact_search | Die Bedeutung der Gefäßheilung nach vaskulärer Intervention = The importance of vascular healing after percutaneous interventions |
| title_full | Die Bedeutung der Gefäßheilung nach vaskulärer Intervention = The importance of vascular healing after percutaneous interventions von Michael Joner |
| title_fullStr | Die Bedeutung der Gefäßheilung nach vaskulärer Intervention = The importance of vascular healing after percutaneous interventions von Michael Joner |
| title_full_unstemmed | Die Bedeutung der Gefäßheilung nach vaskulärer Intervention = The importance of vascular healing after percutaneous interventions von Michael Joner |
| title_short | Die Bedeutung der Gefäßheilung nach vaskulärer Intervention |
| title_sort | die bedeutung der gefaßheilung nach vaskularer intervention the importance of vascular healing after percutaneous interventions |
| title_sub | = The importance of vascular healing after percutaneous interventions |
| topic_facet | Hochschulschrift |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=025686071&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
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