Human genetics: concepts and applications
Saved in:
| Main Author: | |
|---|---|
| Format: | Book |
| Language: | English |
| Published: |
New York
McGraw-Hill
2012
|
| Edition: | 10. ed., internat. student ed. |
| Subjects: | |
| Online Access: | Inhaltsverzeichnis |
| Physical Description: | Getr. Zählung Ill., graph. Darst., Kt. 28 cm |
| ISBN: | 9780071315838 0071315837 |
Staff View
MARC
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| 250 | |a 10. ed., internat. student ed. | ||
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| 300 | |a Getr. Zählung |b Ill., graph. Darst., Kt. |c 28 cm | ||
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Record in the Search Index
| _version_ | 1804149997497745408 |
|---|---|
| adam_text | Titel: Human genetics
Autor: Lewis, Ricki
Jahr: 2012
About the Author iii
Preface xi
Applying Human Genetics xiv
The Human Touch xv
The Lewis Guided Learning System xvi
PART
I Introduction 1
1
H A P T E R
EGG
DONORS
WANTED
510,000 PLUS
EXPENSES
CHAPTER
Overview of Genetics 1 IfiSi Meiosis and
Introducing Genes 2 Development 44
1.2 Levels of Genetics 4
. _ ._. . _ . ^ _ 3.1 The Reproductive System 45
1.3 Genes and Their Environment 8
1.1
1.4 Applications of Genetics 9
3.2 Meiosis 46
3.3 Gamete Maturation 49
3.4 Prenatal Development 53
3.5 BirthDefects 60
CeilS 18 3.6 Maturation and Aging 62
CHAPTER
2.1 Introducing Cells 19
2.2 Cell Components 19
2.3 Cell Division and Death 30
2.4 Cell-Cell Interactions 35
2.5 Stern Cells 36
part 2. Transmission Genetics 69
CHAPTER H Hl C H A P T E R D
Single-Gene Inheritance 69 EJB Beyond Mendel s Laws 89
4.1 Following the Inheritance of One Gene 70 5.1 A New View of Mendelian Genetics 90
4.2 Single-Gene Inheritance Is Rare 73 5.2 When Gene Expression Appears to Alter
4.3 Following the Inheritance of More Than Mendelian Ratios 90
One Gene 79 5#3 Mitochondrial Genes 98
4.4 Pedigree Analysis 82 5.4 Linkage 101
4.5 Family Genome Analysis 84
vi
CHAPTER O ^^^H CHAPTER ö
Matters of Sex 110 139 Genetics of Behavior 149
6.1 Our Sexual Selves 111 8.1 Genes and Behavior 150
6.2 Traits Inherited on Sex Chromosomes 116 8.2 Eating Disorders 151
6.3 Sex-Limited and Sex-Influenced Traits 121 8.3 Sleep 152
6.4 X Inactivation 122 8.4 Intelligence 153
6.5 Genomic Imprinting 124 8.5 Drug Addiction 154
CHAPTER /
Multifactorial Traits 131
7.1 Genes and the Environment Mold Traits 132
7.2 Polygenic Traits Are Continuously Varying 132
7.3 Traditional Ways to Investigate Multifactorial
Traits 137
7.4 Genome-Wide Association Studies 141
7.5 ACIoser Look: Body Weight 144
8.6 Mood Disorders 156
8.7 Schizophrenia 157
8.8 Autism 159
8.9 How Are Behavioral Disorders Related? 160
PART
DNA and Chromosomes 164
10
CHAPTER -• IH^H C H A p T E R
DNA Structure and IKB Gene Action: From
Replication 164 DNA to Protein 179
9.1 Experiments Identify and Describe the 10.1 From DNA to Protein 180
Genetic Material 165
9.2 DNA Structure 169
10.2 Transcription 180
10.3 Translation ofa Protein 185
93 Sft^!?^ l,tol,,l,ll,,lngG n*,IC 104 ProcessingaProtein 191
Contents vii
11
El
R 13
C H A P T E
Chromosomes 235
CHAPTER
Gene Expression
and EpigenetiCS 199 13.1 PortraitofaChromosome 236
11.1 Gene Expression Through Time and Tissue 200 13-2 Visualizing Chromosomes 238
11.2 Control of Gene Expression 203 13 3 Atypical Chromosome Number 243
11.3 Maximizing Genetic Information 205 13-4 Atypical Chromosome Structure 250
11.4 Most ofthe Human Genome Does Not 135 Uniparental Disomy-A Double Dose from
Encode Protein 207 OneParent 255
12
CHAPTER
Gene Mutation 211
12.1 The Nature of Mutations 212
12.2 Two Mutations 212
12.3 Causes of Mutation 216
12.4 Types of Mutations 219
12.5 The Importance of Position 225
12.6 DNARepair 227
PART
Population Genetics 260
14 rsnc .PTER 15
CHAPTER
Constant Allele I. ^SSlI Changing Allele
Frequencies 260 Frequencies 278
14.1 Population Genetics Underlies Evolution 261 15.1 Nonrandom Mating 279
14.2 Constant Allele Frequencies 262 15.2 Migration 280
14.3 Applying Hardy-Weinberg Equilibrium 264 15.3 Genetic Drift 282
14.4 DNA Profiling Ilses Hardy-Weinberg 15.4 Mutation 285
Assumptions 265 15 5 Natura| Select|on 286
15.6 Putting It All Together: PKU 292
15.7 Eugenics 294
viii Contents
16
CHAPTER
Human Ancestry 301
16.1 Human Origins 302
16.2 Molecular Evolution 310
16.3 The Peopling ofthe Planet 317
part D Immunity and Cancer 325
CHAPTER I / *B||H CHAPTER I O
Genetics of Immunity 325 UHU Genetics of Cancer 348
17.1 The Importance of Cell Surfaces 326 18.1 Cancer Is Genetic, But Usually Not
Inherited 349
17.2 The Human Immune System 328
17.3 Abnormal Immunity 333
17.4 Altering Immunity 340
18.2 Characteristics of Cancer Cells 352
18.3 Origins of Cancer Cells 354
18.4 Cancer Genes and MicroRNAs 356
17.5 AGenomic View of Immunity-The
Pathogen s Perspective 344 18.5 Many Genes Contribute to Cancer 362
18.6 Environmental Causes of Cancer 364
18.7 The Personalization of Cancer Diagnosis
andTreatment 366
PART
Genetic Technology 371
I -7 BMH CHAPTER JlXJ
CHAPTER
Genetic Technologies: Hl Genetic Testing
Amplifying, Modifying, and Treatment 388
and Monitoring DNA 371 20.1 GeneticCounseling 389
19.1 PatentingDNA 372 20 2 Genetic Testing 391
19.2 Amplifying DNA 373 203 Treating Genetic Disease 395
19.3 Modifying DNA 375
19.4 Monitoring Gene Function 382
19.5 SilencingDNA 382
Contents ix
CHAPTER 2.1 ^¦H9 CHAPTER / /
Reproductive EBB Genomics 423
Technologies 406 22.1 From Genetics to Genomics 424
21.1 SaviorSiblingsandMore 407 22-2 DNA Sequencing and Genome Synthesis 428
21.2 Infertility and Subfertility 407 22-3 Wavs of Looking at Genomes 430
21.3 Assisted Reproductive Technologies 410 224 Personal Genome Sequencing 434
21.4 Extra Embryos 417
Glossary G-1
Credits C-1
Index 1-1
Contents
|
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| edition | 10. ed., internat. student ed. |
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| id | DE-604.BV040696892 |
| illustrated | Illustrated |
| indexdate | 2024-07-10T00:31:55Z |
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| isbn | 9780071315838 0071315837 |
| language | English |
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| physical | Getr. Zählung Ill., graph. Darst., Kt. 28 cm |
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| publisher | McGraw-Hill |
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| spelling | Lewis, Ricki Verfasser aut Human genetics concepts and applications Ricki Lewis 10. ed., internat. student ed. New York McGraw-Hill 2012 Getr. Zählung Ill., graph. Darst., Kt. 28 cm txt rdacontent n rdamedia nc rdacarrier Humangenetik (DE-588)4072653-8 gnd rswk-swf Human genetics Human genetics / Problems, exercises, etc Humangenetik (DE-588)4072653-8 s DE-604 HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=025677504&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Lewis, Ricki Human genetics concepts and applications Humangenetik (DE-588)4072653-8 gnd |
| subject_GND | (DE-588)4072653-8 |
| title | Human genetics concepts and applications |
| title_auth | Human genetics concepts and applications |
| title_exact_search | Human genetics concepts and applications |
| title_full | Human genetics concepts and applications Ricki Lewis |
| title_fullStr | Human genetics concepts and applications Ricki Lewis |
| title_full_unstemmed | Human genetics concepts and applications Ricki Lewis |
| title_short | Human genetics |
| title_sort | human genetics concepts and applications |
| title_sub | concepts and applications |
| topic | Humangenetik (DE-588)4072653-8 gnd |
| topic_facet | Humangenetik |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=025677504&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
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