Culture negative orthopedic biofilm infections:
Saved in:
| Format: | Book |
|---|---|
| Language: | English |
| Published: |
Berlin ; Heidelberg [u.a.]
Springer
2012
|
| Series: | Springer series on biofilms
7 |
| Subjects: | |
| Online Access: | Inhaltsverzeichnis Klappentext |
| Physical Description: | X, 144 S. Ill., graph. Darst. |
| ISBN: | 9783642295539 |
Staff View
MARC
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Record in the Search Index
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| adam_text | Contents
The Problem
of Culture-Negative Infections
.................... 1
G.D.
Ehrlich,
P.J. DeMeo, and J.W. Costerton
Culture-Negative Infections in Orthopedic Surgery
............... 17
G.D.
Ehrlich,
Patrick DeMeo, Michael Palmer,
T.J. Sauber, Dan
Altman.
Greg
Altman,
Nick Sotereanos,
Stephen Conti,
Mark Baratz, Gerhard Maale.
Fen
Z. Hu, J.
Christopher Post, Laura
Ništico,
Rachael Kreft. Luanne
Hall-Stoodley, J.W. Costerton, and Paul Stoodley
Improved
Diagnosis of
Biofilm
Infections Using Various Molecular
Methods
................................................ 29
Trine
Rolighed
Thomsen, Yijuan Xu, Jan Lorenzen, Per Halkjasr Nielsen,
and
Henrik
Carl Sch0nheyder
Improved Outcomes Via Integrated Molecular Diagnostics and
Biofilm
Targeted Therapeutics
..................................... 43
John P. Kennedy and Curtis E. Jones
Immunological Methods for Staphylococcus aureus Infection Diagnosis
and Prevention
........................................... 61
Nathan K. Archer, J. William Costerton, Jeff G.
Leid,
and Mark E. Shirtliff
Diagnosing Periprosthetic Joint Infection: Cultures, Molecular Markers,
and the Ibis Technology
.................................... 77
Javad Parvizi
Infections
Associated with Severe Open
Tibial
Fractures
.......... 87
Robert V. O Toole
Second-Generation Molecular Diagnostics and Strategies for Preventing
Periprosthetic Joint Infections
............................... 97
Nicholas Sotereanos
χ
Contents
Treatment of Orthopedic Infections: Addressing the
Biofilm
Issue
...
Ill
Heinz
Winkler
Towards a New Paradigm in the Diagnosis and Treatment
of Orthopedic Infections
................................... 129
G.D.
Ehrlich,
J.W.
Costerton,
D.
Altman, G. Altman,
M.
Palmer, C.
Post,
P. Stoodley, and P.J. DeMeo
Index
.................................................. 141
Springer
Series
on
Biofilms
Garth
D.
Ehrlich ■ Patrick
J.
DeMeo ■
J.
William Costerton
· Heinz Winkler Editors
Culture
Negative
Orthopedic
Biofilm
Infections
During the recent transition between acute diseases caused by swarms of single
planktonic
bacteria, and chronic infections caused by bacteria growing in slime-enclosed
biofilms,
a general clinical consensus has emerged that pathologies with bacterial etiologies are
frequently culture negative. Because
biofilm
infections now affect
17
million Americans
per year (killing approximately
450,000),
the suggestion that these common and lethal
infections regularly go unnoticed by the only FDA-approved method for their detection
and characterization is a matter of urgent concern. Biologically, we would expect that
planktonic
bacterial cells would colonize any new surface, including the surface of an
agar
plate, while the specialized sessile cells of
a biofilm
community would have no
such proclivity. In the study of
biofilm
diseases ranging from
otitis
media to prostatitis,
it was found that direct microscopy and
DNA-
and RNA-based molecular methods
regularly document the presence of living bacteria in tissues and samples that are cul¬
ture negative. The editors selected orthopedic
biofilm
infections as the subject of this
book because these infections occur against a background of microbiological sterility
in which modern molecular methods would be expected to find bacterial
DNA, RNA-
based
microscopic methods would be expected to locate bacterial cells, and cultures
would be negative. Moreover, in Orthopedics we find an already biofilm-adapted surgical
group in which current strategies are based on the meticulous removal of compromised
tissues, antibiotic options are based on high biofilm-killing local doses, and there are
practical bedside strategies for dealing with
biofilm
infections. So here is where the new
paradigm of
biofilm
infection meets the equally new paradigm of the culture negativity
of
biofilms,
and this volume presents a conceptual synthesis that may soon combine
the most effective molecular methods for the detection and identification of bacteria
with a surgical discipline that is ready to help patients.
|
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| dewey-raw | 579 |
| dewey-search | 579 |
| dewey-sort | 3579 |
| dewey-tens | 570 - Biology |
| discipline | Biologie Medizin |
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| spelling | Culture negative orthopedic biofilm infections Garth D. Ehrlich ..., ed. Berlin ; Heidelberg [u.a.] Springer 2012 X, 144 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Springer series on biofilms 7 Biowissenschaften Life sciences Microbial ecology Microbiology Bacteriology Bewegungsapparat (DE-588)4006318-5 gnd rswk-swf Infektion (DE-588)4161650-9 gnd rswk-swf Bakterielle Infektion (DE-588)4004301-0 gnd rswk-swf Orthopädische Chirurgie (DE-588)4075710-9 gnd rswk-swf Biofilm (DE-588)4232790-8 gnd rswk-swf 1\p (DE-588)4143413-4 Aufsatzsammlung gnd-content Orthopädische Chirurgie (DE-588)4075710-9 s Infektion (DE-588)4161650-9 s Biofilm (DE-588)4232790-8 s DE-604 Bewegungsapparat (DE-588)4006318-5 s Bakterielle Infektion (DE-588)4004301-0 s 2\p DE-604 Ehrlich, Garth D. Sonstige oth Erscheint auch als Online-Ausgabe 978-3-642-29554-6 Springer series on biofilms 7 (DE-604)BV022504995 7 Digitalisierung UB Regensburg application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=025510860&sequence=000003&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis Digitalisierung UB Regensburg application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=025510860&sequence=000004&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA Klappentext 1\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk 2\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk |
| spellingShingle | Culture negative orthopedic biofilm infections Springer series on biofilms Biowissenschaften Life sciences Microbial ecology Microbiology Bacteriology Bewegungsapparat (DE-588)4006318-5 gnd Infektion (DE-588)4161650-9 gnd Bakterielle Infektion (DE-588)4004301-0 gnd Orthopädische Chirurgie (DE-588)4075710-9 gnd Biofilm (DE-588)4232790-8 gnd |
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| title | Culture negative orthopedic biofilm infections |
| title_auth | Culture negative orthopedic biofilm infections |
| title_exact_search | Culture negative orthopedic biofilm infections |
| title_full | Culture negative orthopedic biofilm infections Garth D. Ehrlich ..., ed. |
| title_fullStr | Culture negative orthopedic biofilm infections Garth D. Ehrlich ..., ed. |
| title_full_unstemmed | Culture negative orthopedic biofilm infections Garth D. Ehrlich ..., ed. |
| title_short | Culture negative orthopedic biofilm infections |
| title_sort | culture negative orthopedic biofilm infections |
| topic | Biowissenschaften Life sciences Microbial ecology Microbiology Bacteriology Bewegungsapparat (DE-588)4006318-5 gnd Infektion (DE-588)4161650-9 gnd Bakterielle Infektion (DE-588)4004301-0 gnd Orthopädische Chirurgie (DE-588)4075710-9 gnd Biofilm (DE-588)4232790-8 gnd |
| topic_facet | Biowissenschaften Life sciences Microbial ecology Microbiology Bacteriology Bewegungsapparat Infektion Bakterielle Infektion Orthopädische Chirurgie Biofilm Aufsatzsammlung |
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