Mammography screening: truth, lies and controversy
Saved in:
| Main Author: | |
|---|---|
| Format: | Book |
| Language: | English |
| Published: |
London
Radcliffe Publishing
2012
|
| Online Access: | Inhaltsverzeichnis |
| Physical Description: | XI, 388 S. Ill., graph. Darst. |
| ISBN: | 9781846195853 |
Staff View
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Record in the Search Index
| _version_ | 1804149523729088512 |
|---|---|
| adam_text | Titel: Mammography screening
Autor: Gøtzsche, Peter C
Jahr: 2012
Contents
Foreword by lona Heath vii
Foreword by Fran Visco ix
Acknowledgements xi
1 Introduction 1
• What it really means to be controversial 5
• Our collaboration with the media 10
2 Important issues in cancer screening 13
• What it means to have cancer 13
• Overdiagnosis and overtreatment 15
• Erroneous diagnoses and carcinoma in situ 16
• Basic issues in cancer epidemiology 19
• Randomised trials, observational studies and a little statistics 20
• Why screening leads to misleading survival statistics 22
• Why 10-year survival is also misleading 23
3 Does screening work in Sweden? 29
4 Stonewalling the Cochrane report on screening 34
• The Danish National Board of Health interferes with our report 40
5 Troubling results in the Lancet 46
• The Canadian trials 50
• Media storm 52
• Email from researchers 5 5
• Our collaboration with the trialists 56
• Ten letters to the editor 58
• Creative manipulations in Sweden 60
• Peter Dean, a remarkable character 63
Contents
• Bad manners also in Norway 66
• Continued troubles in Denmark 68
6 Harms dismissed by the Cochrane Breast Cancer Group 73
• The process with the Cochrane review 75
• Of mites and men 77
• Confusion over who is in charge 78
7 The Lancet publishes the harms of screening 85
• Vitriolic mass email from Peter Dean 90
• Beating about the bush in the United Kingdom 93
• Condemnations in Sweden 95
• Contempt of science in Denmark and Norway 99
8 Delayed media storm in the United States after our 2001 reviews 103
• Miettinen and Henschke s cherry-picking in the Lancet 107
• Additional reactions in the United States 108
9 The Danish National Board of Health circles the wagons 114
10 US and Swedish 2002 meta-analyses 120
• US Preventive Services Task Force s meta-analysis 120
• Nyström s updated Swedish meta-analysis 121
11 Scientific debates in the United States 126
• Peter Dean is wrong again 126
• Multiple errors in the International Journal of Epidemiology 130
12 Publication of entire Cochrane review obstructed for 5 years 136
• Cochrane editors stonewall our Cochrane review 138
• Lessons for the future 143
• Welcome results in France 145
13 Editorial misconduct in the European Journal of Cancer 147
• Editorial misconduct 151
• Threats, intimidation and falsehoods 155
• Debates in the Scientist and the Cancer Letter 158
14 Tabár s beyond reason studies 163
• Criticism of our work in the Journal of Surgical Oncology 168
• iv •
Contents
15 Other observational studies of breast cancer mortality 173
• The United States and the United Kingdom 174
• Denmark, Lynge s 2005 study 175
• Denmark, our 2010 study 177
16 Overdiagnosis and overtreatment 185
• Cancers that regress spontaneously 186
• The 1986 UK Forrest report 188
• Overdiagnosis in the randomised trials 189
• Systematic review of overdiagnosis in observational studies 194
• Observational studies from Denmark and New South Wales 200
• The doubt industry 202
• Duffy s studies on overdiagnosis 205
• Lynge s studies on overdiagnosis 207
• Carcinoma in situ and the increase in mastectomies 210
17 Ad hominem attacks: a measure of desperation? 220
• UK statistician publishes in Danish 222
• Inappropriate name-dropping 223
• Further ad hominem arguments 226
• Lynge s unholy mixture of politics and science 227
• Ad hominem attacks ad infinitum 230
18 US recommendations for women aged 40-49 years 238
19 What have women been told? 245
• Website information on screening 245
• Invitations to screening 247
• A scandalous revision of the Danish screening leaflet 252
• Our screening leaflet 254
• Breast screening: the facts, or maybe not 255
• American Cancer Society 262
• Information from other cancer societies 267
• Getting funding or not getting funding 271
• What do women believe? 272
20 Extraordinary exaggerations 279
• What is the ratio between benefits and harms? 280
• v •
Contents
• Duffy s funny numbers 282
• Exaggerating 25-fold 287
• The exaggerations finally backfire 292
• The ultimate exaggeration 294
21 Tabár threatens the BMJ with litigation 298
22 Falsehoods and perceived censorship in Sweden 306
23 Celebrating 20 years of breast screening in the United Kingdom 311
24 Can screening work? 320
• Plausible effect based on tumour sizes in the trials 320
• Lead time 323
• Plausible effect based on tumour stages in the trials 324
• No decrease in advanced cancers 326
25 Where is screening at today? 331
• Problems with reading mammograms 332
• False promises 333
• Important information is being ignored 336
• Beliefs warp evidence at conferences 338
• Does breast screening make women live longer? 340
26 Where next? 347
• Is screening a religion? 351
• A press release from Radiology that wasn t 352
• Has all my struggle achieved anything? 353
• Why has so much evidence about screening been distorted? 357
• Time to stop breast cancer screening 358
Appendix 1 : Tabár s explanations in the Cancer Letter and our replies 363
Appendix 2: Our 2008 mammography screening leaflet 369
Appendix 3: The press release Radiology withdrew at the last minute 381
Index 384
• vi •
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| isbn | 9781846195853 |
| language | English |
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| spelling | Gøtzsche, Peter C. 1949- Verfasser (DE-588)1061093158 aut Mammography screening truth, lies and controversy Peter C. Gøtzsche London Radcliffe Publishing 2012 XI, 388 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=025306838&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Gøtzsche, Peter C. 1949- Mammography screening truth, lies and controversy |
| title | Mammography screening truth, lies and controversy |
| title_auth | Mammography screening truth, lies and controversy |
| title_exact_search | Mammography screening truth, lies and controversy |
| title_full | Mammography screening truth, lies and controversy Peter C. Gøtzsche |
| title_fullStr | Mammography screening truth, lies and controversy Peter C. Gøtzsche |
| title_full_unstemmed | Mammography screening truth, lies and controversy Peter C. Gøtzsche |
| title_short | Mammography screening |
| title_sort | mammography screening truth lies and controversy |
| title_sub | truth, lies and controversy |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=025306838&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
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