Bioinformatics and drug discovery:
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
New York, NY [u.a.]
Humana Press
2012
|
| Ausgabe: | 2. ed. |
| Schriftenreihe: | Methods in molecular biology
910 |
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | XII, 374 S. Ill., graph. Darst. |
| ISBN: | 9781617799648 |
Internformat
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| 245 | 1 | 0 | |a Bioinformatics and drug discovery |c ed. by Richard S. Larson |
| 250 | |a 2. ed. | ||
| 264 | 1 | |a New York, NY [u.a.] |b Humana Press |c 2012 | |
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| 650 | 4 | |a Médicaments - Développement | |
| 650 | 4 | |a Drug development | |
| 650 | 4 | |a Bioinformatics | |
| 650 | 4 | |a High throughput screening (Drug development) | |
| 650 | 4 | |a Combinatorial chemistry | |
| 650 | 4 | |a Drug Design | |
| 650 | 4 | |a Computational Biology |x methods | |
| 650 | 4 | |a Drug Evaluation, Preclinical | |
| 650 | 4 | |a Genetic Techniques | |
| 650 | 4 | |a Microarray Analysis | |
| 650 | 4 | |a Pharmacogenetics |x methods | |
| 650 | 0 | 7 | |a Bioinformatik |0 (DE-588)4611085-9 |2 gnd |9 rswk-swf |
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| 999 | |a oai:aleph.bib-bvb.de:BVB01-025213802 | ||
Datensatz im Suchindex
| _version_ | 1804149400873730048 |
|---|---|
| adam_text | Titel: Bioinformatics and drug discovery
Autor: Larson, Richard S
Jahr: 2012
Contents
Preface.......................................................... v
Acknowledgments...................................................... vü
Contributors...................................................... xi
1 Cell Perturbation Screens for Target Identification by RNAi.............. 1
Kubilay Demir and Michael Boutros
2 Using Functional Genomics to Identify Drug Targets: A Dupuytren s
Disease Example............................................... 15
Mirela Sedic, Sandra Kraljevic Pavelic, and Karlo Hock
3 Functional Characterization of Human Genes from Exon Expression
and RNA Interference Results..................................... 33
Dorothea Emig, Hagen Blankenburg, Fidel Ramirez, and Mario Albrecht
4 Barcode Sequencing for Understanding Drug-gene Interactions........... 55
Andrew M. Smith, Tanja Durbic, Saranya Kittanakom,
Guri Giaever, and Corey Nislow
5 High-Throughput Sequencing of the Methylome Using Two-Base Encoding . 71
Christina A. Bormann Chung
6 Applications and Limitations of In Silico Models in Drug Discovery........ 87
Ahmet Sacan, Sean Ekins, and Sandhya Kortagere
7 Compound Collection Preparation for Virtual Screening................. 125
Cristian G. Bologa and Tudor I. Oprea
8 Mapping Between Databases of Compounds and Protein Targets.......... 145
Sovel Muresan, Markus Sitzmann, and Christopher Southan
9 Predictive Cheminformatics in Drug Discovery: Statistical Modeling
for Analysis of Micro-array and Gene Expression Data................... 165
N. Sukumar, Michael P. Krein, and Mark J. Embrechts
10 Advances in Nuclear Magnetic Resonance for Drug Discovery............. 195
Laurel O. Sillerud and Richard S. Larson
11 Human ABC Transporter ABCG2 in Cancer Chemotherapy:
Drug Molecular Design to Circumvent Multidrug Resistance............. 267
Toshihisa Ishikawa, Hikaru Saito, Hiroyuki Hirano,
Yutaka Inoue, and Yoji Ikegami
12 Protein Interactions: Mapping Interactome Networks to Support
Drug Target Discovery and Selection............................... 279
Javier De Las Rivas and Carlos Prieto
IX
x Contents
13 Linking Variants from Genome-Wide Association Analysis to
Function via Transcriptional Network Analysis........................ 297
Benjamin J. Keller, Sebastian Martini, and Viji Nair
14 Models of Excitation-Contraction Coupling in Cardiac Ventricular Myocytes . 309
M. Saleet Jafri
15 Integration of Multiple Ubiquitin Signals in Proteasome Regulation........ 337
Marta Isasa, Alice Zuin, and Bernât Crosas
Index............................................................... 371
|
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| dewey-full | 615/.19 |
| dewey-hundreds | 600 - Technology (Applied sciences) |
| dewey-ones | 615 - Pharmacology and therapeutics |
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| dewey-search | 615/.19 |
| dewey-sort | 3615 219 |
| dewey-tens | 610 - Medicine and health |
| discipline | Biologie Informatik Chemie-Ingenieurwesen Medizin |
| edition | 2. ed. |
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| id | DE-604.BV040359936 |
| illustrated | Illustrated |
| indexdate | 2024-07-10T00:22:26Z |
| institution | BVB |
| isbn | 9781617799648 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-025213802 |
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| physical | XII, 374 S. Ill., graph. Darst. |
| publishDate | 2012 |
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| publisher | Humana Press |
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| series | Methods in molecular biology |
| series2 | Methods in molecular biology Springer protocols |
| spelling | Bioinformatics and drug discovery ed. by Richard S. Larson 2. ed. New York, NY [u.a.] Humana Press 2012 XII, 374 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Methods in molecular biology 910 Springer protocols Bio-informatique Chimie combinatoire Criblage à haut débit (Développement des médicaments) Médicaments - Développement Drug development Bioinformatics High throughput screening (Drug development) Combinatorial chemistry Drug Design Computational Biology methods Drug Evaluation, Preclinical Genetic Techniques Microarray Analysis Pharmacogenetics methods Bioinformatik (DE-588)4611085-9 gnd rswk-swf Arzneimittelentwicklung (DE-588)4143176-5 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content Bioinformatik (DE-588)4611085-9 s Arzneimittelentwicklung (DE-588)4143176-5 s b DE-604 Larson, Richard S. Sonstige oth Methods in molecular biology 910 (DE-604)BV035362695 910 HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=025213802&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Bioinformatics and drug discovery Methods in molecular biology Bio-informatique Chimie combinatoire Criblage à haut débit (Développement des médicaments) Médicaments - Développement Drug development Bioinformatics High throughput screening (Drug development) Combinatorial chemistry Drug Design Computational Biology methods Drug Evaluation, Preclinical Genetic Techniques Microarray Analysis Pharmacogenetics methods Bioinformatik (DE-588)4611085-9 gnd Arzneimittelentwicklung (DE-588)4143176-5 gnd |
| subject_GND | (DE-588)4611085-9 (DE-588)4143176-5 (DE-588)4143413-4 |
| title | Bioinformatics and drug discovery |
| title_auth | Bioinformatics and drug discovery |
| title_exact_search | Bioinformatics and drug discovery |
| title_full | Bioinformatics and drug discovery ed. by Richard S. Larson |
| title_fullStr | Bioinformatics and drug discovery ed. by Richard S. Larson |
| title_full_unstemmed | Bioinformatics and drug discovery ed. by Richard S. Larson |
| title_short | Bioinformatics and drug discovery |
| title_sort | bioinformatics and drug discovery |
| topic | Bio-informatique Chimie combinatoire Criblage à haut débit (Développement des médicaments) Médicaments - Développement Drug development Bioinformatics High throughput screening (Drug development) Combinatorial chemistry Drug Design Computational Biology methods Drug Evaluation, Preclinical Genetic Techniques Microarray Analysis Pharmacogenetics methods Bioinformatik (DE-588)4611085-9 gnd Arzneimittelentwicklung (DE-588)4143176-5 gnd |
| topic_facet | Bio-informatique Chimie combinatoire Criblage à haut débit (Développement des médicaments) Médicaments - Développement Drug development Bioinformatics High throughput screening (Drug development) Combinatorial chemistry Drug Design Computational Biology methods Drug Evaluation, Preclinical Genetic Techniques Microarray Analysis Pharmacogenetics methods Bioinformatik Arzneimittelentwicklung Aufsatzsammlung |
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