The neuroscience of tinnitus:
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| Main Author: | |
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| Format: | Book |
| Language: | English |
| Published: |
Oxford
Oxford Univ. Press
2012
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| Edition: | 1. ed. |
| Subjects: | |
| Online Access: | Inhaltsverzeichnis |
| Physical Description: | XV, 301 S. Ill., graph. Darst. |
| ISBN: | 9780199605606 |
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| 245 | 1 | 0 | |a The neuroscience of tinnitus |c Jos J. Eggermont |
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Record in the Search Index
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| adam_text | Titel: The neuroscience of tinnitus
Autor: Eggermont, Jos J
Jahr: 2012
Contents
Preface ix
List of abbreviations xiii
1 What is tinnitus? 1
1.1 Objective tinnitus 2
1.2 Subjective tinnitus 3
1.3 How does tinnitus sound? 3
1.4 Is tinnitus a form of pain? 6
1.5 Is tinnitus aberrant spontaneous activity? 7
1.6 Mechanisms that may be involved in SFR changes 12
1.7 Summary 14
2 Epidemiology and etiology 15
2.1 What is significant tinnitus? 15
2.2 Tinnitus prevalence across the life span 16
2.3 Tinnitus in children 18
2.4 Tinnitus in the elderly 19
2.5 Body sounds (objective tinnitus) 20
2.6 Subjective tinnitus of peripheral origin 2/
2.7 Tinnitus of somatic origin 27
2.8 Genetics of tinnitus 28
2.9 Vestibular schwannoma and gaze-evoked tinnitus 31
2.10 Stress and tinnitus 32
2.11 Tinnitus of unknown etiology 32
2.12 Summary 34
3 Listening to tinnitus 35
3.1 Pitch 35
3.2 Loudness 36
3.3 Loudness recruitment 39
3.4 Hyperacusis 43
3.5 Masking 44
3.6 Residual inhibition 46
3.7 Psychological aspects 48
3.8 Summary 54
4 Objective assessment of tinnitus 55
4.1 Otoacoustic emissions 55
4.2 Metabolism- and blood-flow-based non-invasive measures
of brain function 56
Vi CONTENTS
4.3 Imaging of tinnitus 57
4.4 Extracranial^ recorded neuronal activity of auditory cortex 64
AS Summary 72
5 Do animals have tinnitus? 73
5.1 Commonly used animal models 74
5.2 Validity criteria for animal models 75
5.3 Behavioral animal models of tinnitus 75
5.4 Summary 91
6 The salicylate model of tinnitus 92
6.1 Structural changes caused by salicylate 93
6.2 Physiological and neural changes 95
6.3 Molecular changes 105
6.4 Summary 112
7 The sensorineural hearing loss model of tinnitus 114
7.1 Structural changes in the auditory system following noise trauma 114
7.2 Physiological and neural changes 119
7.3 Molecular changes 133
7.4 Summary 141
8 The somatic tinnitus model 143
8.1 The trigeminal ganglion and cochlear blood flow 144
8.2 Somatosensory innervation of the auditory brainstem and midbrain 146
8.3 Physiological and neural changes 150
8.4 Summary 153
9 The neural synchrony model of tinnitus 154
9.1 What is neural synchrony? 155
9.2 Measuring neural micro synchrony 156
9.3 Where do the common inputs to cortical neurons originate? 160
9.4 Neural synchrony measures depend on firing rates 161
9.5 Consequences of neural synchrony 161
9.6 Burst firing: serial firing synchrony 163
9.7 Increased neural synchrony in animal brains 165
9.8 Macroscopic synchrony in tinnitus patients 170
9.9 Role of neural synchrony in tinnitus perception 172
9.10 Summary 173
10 Tinnitus and aging 174
10.1 Causes of aging 174
10.2 Structural changes 177
10.3 Electrophysiological changes iS3
10.4 Molecular biology of aging in relation to tinnitus 185
10.5 Comparison of ARHL with NIHL 192
CONTENTS vii
11 Hyperactivity and hypersynchrony in neural networks as
substrates for tinnitus? 195
11.1 Summary of bottom-up mechanisms: salicylate, noise trauma, aging 195
11.2 Top-down aspects of perception 200
11.3 The resting brain networks 205
11.4 Imagery, hallucinations, and tinnitus 208
11.5 Similarities between tinnitus and epilepsy mechanisms 209
11.6 The limbic system, prefrontal cortex, and tinnitus 210
11.7 Can hyperacusis and tinnitus both result from an auditory
system gain change? 214
12 Management of tinnitus 217
12.1 Sound therapy (passive) 217
12.2 Direct stimulation of auditory cortex and deep brain structures 223
12.3 Transcranial magnetic stimulation 224
12.4 Tinnitus retraining therapy and cognitive behavioral therapy 226
12.5 Drugs, clinical trials 227
13 Future directions 230
13.1 Molecular and cellular mechanisms 230
13.2 Modeling and theoretical aspects 230
13.3 Physiological mechanisms 230
13.4 Psychophysical and functional consequences of tinnitus 232
13.5 Targeted treatment requires a typology of tinnitus 232
13.6 Outlook to new treatment options? 233
References 235
Author index 285
Subject index 287
|
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| author | Eggermont, Jos J. |
| author_facet | Eggermont, Jos J. |
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| dewey-tens | 610 - Medicine and health |
| discipline | Medizin |
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| indexdate | 2024-07-10T00:21:18Z |
| institution | BVB |
| isbn | 9780199605606 |
| language | English |
| lccn | 2012933691 |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-025163154 |
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| physical | XV, 301 S. Ill., graph. Darst. |
| publishDate | 2012 |
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| spelling | Eggermont, Jos J. Verfasser aut The neuroscience of tinnitus Jos J. Eggermont 1. ed. Oxford Oxford Univ. Press 2012 XV, 301 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Ohrgeräusch (DE-588)4121423-7 gnd rswk-swf Neurowissenschaften (DE-588)7555119-6 gnd rswk-swf Ohrgeräusch (DE-588)4121423-7 s Neurowissenschaften (DE-588)7555119-6 s DE-604 HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=025163154&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Eggermont, Jos J. The neuroscience of tinnitus Ohrgeräusch (DE-588)4121423-7 gnd Neurowissenschaften (DE-588)7555119-6 gnd |
| subject_GND | (DE-588)4121423-7 (DE-588)7555119-6 |
| title | The neuroscience of tinnitus |
| title_auth | The neuroscience of tinnitus |
| title_exact_search | The neuroscience of tinnitus |
| title_full | The neuroscience of tinnitus Jos J. Eggermont |
| title_fullStr | The neuroscience of tinnitus Jos J. Eggermont |
| title_full_unstemmed | The neuroscience of tinnitus Jos J. Eggermont |
| title_short | The neuroscience of tinnitus |
| title_sort | the neuroscience of tinnitus |
| topic | Ohrgeräusch (DE-588)4121423-7 gnd Neurowissenschaften (DE-588)7555119-6 gnd |
| topic_facet | Ohrgeräusch Neurowissenschaften |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=025163154&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
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