Holdings: Apicomplexan parasites

Apicomplexan parasites: molecular approaches toward targeted drug development

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Bibliographic Details
Other Authors:	Becker, Katja 1965- (Editor)
Format:	Book
Language:	English
Published:	Weinheim Wiley-Blackwell 2011
Series:	Drug discovery in infectious diseases 2
Subjects:	Parasitäre Krankheit Sporentierchen Arzneimittelentwicklung Protozoan vaccines / Development Apicomplexa Aufsatzsammlung
Online Access:	Inhaltsverzeichnis
Physical Description:	XXI, 528 S. Ill., graph. Darst.
ISBN:	9783527327317 3527327312

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MARC


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adam_text	IMAGE 1 VII CONTENTS FOREWORD V PREFACE XI LIST OF CONTRIBUTORS XIII PART ONE SCREENING, BIOINFORMATICS, CHEMOINFORMATICS, AND DRUG DESIGN 1 1 DRUG DISCOVERY APPROACHES TOWARD ANTI-PARASITIC AGENTS 3 ANDREAS ROHWER, RICHARDJ. MARHOEFER, CONOR R. CAFFREY, AND PAUL M. SEHER 2 NEW BIOINFORMATIC STRATEGIES AGAINST APICOMPLEXAN PARASITES 21 THOMAS DANDEKAR AND KE XIAO 3 SORTING POTENTIAL THERAPEUTIC TARGETS IN APICOMPLEXA 35 JAN A. HISS AND CISBERT SCHNEIDER 4 ALTERNATIVES TO DRUG DEVELOPMENT IN THE APICOMPLEXA 53 THEO P.M. SCHETTERS PART TWO METABOLIC PATHWAYS AND PROCESSES ADDRESSED BY CURRENT DRUG-DISCOVERY APPROACHES 75 5 ENERGY METABOLISM AS AN ANTIMALARIAL DRUG TARGET 77 ESTHERJORTZIK AND KATJA BECKER 6 POLYAMINES IN APICOMPLEXAN PARASITES 97 INGRID B. MUELLER, ROBIN DAS GUPTA, KAI LUEERSEN, CARSTEN WRENGER, AND ROLFD. WALTER BIBLIOGRAFISCHE INFORMATIONEN HTTP://D-NB.INFO/1006150196 DIGITALISIERT DURCH IMAGE 2 VIII I CONTENTS 7 THE REDUCING MILIEU OF PARASITIZED CELLS AS A TARGET OF ANTIMALARIAL AGENTS: METHYLENE BLUE AS AN ETHICAL DRUG 215 PETER MEISSNER, HEIKE ADLER, DENIS KASOZI, KARIN FRITZ-WOLF AND R. HEINER SCHIRMER 8 LIPIDS AS DRUG TARGETS FOR MALARIA THERAPY 137 HENRIJ. VIAL, DIANA PENARETE, SHARON WEIN, SERGIO CALDARELLI, LAURENT FRAISSE, AND SUZANNE PEYROTTES 9 TARGETING APICOPLAST PATHWAYS IN PLASMODIUM 163 SNOBER S. MIR, SUBIR BISWAS, AND SAMAN HABIB 10 LIPOIC ACID ACQUISITION AND CLUTATHIONE BIOSYNTHESIS IN APICOMPLEXAN PARASITES 187 JANET STORM, EVA-MARIA PATZEWITZ, AND SYLKE MUELLER 11 ANTIMALARIAL DRUGS AND MOLECULES INHIBITING HEMOZOIN FORMATION 205 UDAY BANDYOPADHYAY AND SUMANTA DEY 12 EXPLOITING THE VITAMIN METABOLISM OF APICOMPLEXA AS DRUG TARGETS 235 CARSTEN WRENGER AND INGRID B. MUELLER 13 VITAMIN BIOSYNTHETIC PATHWAYS, THE PLP SYNTHASE COMPLEX, AND THE POTENTIAL FOR TARGETING PROTEIN-PROTEIN INTERACTION 251 IVO TEWS AND IRMGARD SINNING 14 TARGETING PROKARYOTIC ENZYMES IN THE EUKARYOTIC PATHOGEN CRYPTOSPORIDIUM 271 SURESH KUMAR CORLA, COREY JOHNSON, JIHAN KHAN, XIN SUN, LISA SHARLING, BORIS STRIEPEN, AND LIZBETH HEDSTROM PART THREE DRUG TARGETS IN APICOMPLEXAN PARASITES 287 15 NOVEL APICOMPLEXAN PHOSPHATASES AND IMMUNOPHILINS AS DOMAIN-SPECIFIC DRUG TARGETS 289 SAILEN BARIK 16 DEHYDROGENASES AND ENZYMES OF THE MITOCHONDRIAL ELECTRON TRANSPORT CHAIN AS ANTI-APICOMPLEXAN DRUG TARGETS 307 KATHLEEN ZOCHER, STEFAN RAHLFS, AND KATJA BECKER 17 CALCIUM-DEPENDENT PROTEIN KINASES AS DRUG TARGETS IN APICOMPLEXAN PARASITES 319 DOMINIK KUGELSTADT, BIANCA DERRER, AND BARBARA KAPPES IMAGE 3 CONTENTS IX 18 PROTEIN ACYLATION: NEW POTENTIAL TARGETS FOR INTERVENTION AGAINST THE APICOMPLEXA 335 JOANA M. SANTOS, CHRISTIAN HEDBERG, AND DOMINIQUE SOLDATI-FAVRE 19 DRUGS AND DRUG TARGETS IN NEOSPORA CANINUM AND RELATED APICOMPLEXANS 359 JOACHIM MUELLER, NORBERT MUELLER, AND ANDREW HEMPHILL PART FOUR COMPOUNDS 373 20 SUBVERSIVE SUBSTRATES OF CLUTATHIONE REDUCTASES FROM PLASMODIUM FALCIPARUM- NFECTED RED BLOOD CELLS AS ANTIMALARIAL AGENTS 375 ELISABETH DAVIOUD-CHARVET AND DON ANTOINE LANFRANCHI 21 FERROQUINE: A CONCEALED WEAPON 397 CHRISTOPHE BIOT, BRUNO PRADINES, AND DANIEL DIVE 22 CURRENT ASPECTS OF ENDOPEROXIDES IN ANTIPARASITIC CHEMOTHERAPY 413 DENIS MATOVU KASOZI, STEFAN RAHLFI, AND KATJA BECKER 23 PLASMODIUM HSP90 AS AN ANTIMALARIAL TARGET 431 C. SRIDHAR PRASAD, NICHOLAS D.P. COSFORD, AND SAILEN BARIK 24 DRUG DISCOVERY AGAINST BABESIA AND TOXOPLASMA 453 MOHAMAD ALAA TERKAWI AND IKUO IGARASHI 25 SEARCH FOR DRUGS AND DRUG TARGETS AGAINST BABESIA BOVIS, BABESIA BIGEMINA, BABESIA CABALLI, AND BABESIA [THEILERIA) EQUI 469 SABINE BORK-MIMM 26 ORLISTAT: A REPOSITIONING OPPORTUNITY AS A GROWTH INHIBITOR OF APICOMPLEXAN PARASITES? 481 CHRISTIAN MICULKA, HON Q. TRAN, THORSTEN MEYER, ANJA R. HECKEROTH, STEFAN BAUMEISTER, FRANK SEEBER, AND PAUL M. SELZER 27 RECENT DRUG DISCOVERY AGAINST CRYPTOSPORIDIUM 493 JEAN-FRANGOIS ROSSIGNOL,J. EDWARD SEMPLE, ANDREW V. STACHULSKI, AND CILLES GARGALA INDEX 513
any_adam_object	1
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dewey-raw	615.19
dewey-search	615.19
dewey-sort	3615.19
dewey-tens	610 - Medicine and health
discipline	Medizin
format	Book
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isbn	9783527327317 3527327312
language	English
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series	Drug discovery in infectious diseases
series2	Drug discovery in infectious diseases
spelling	Apicomplexan parasites molecular approaches toward targeted drug development ed. by Katja Becker Weinheim Wiley-Blackwell 2011 XXI, 528 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Drug discovery in infectious diseases 2 Parasitäre Krankheit (DE-588)4044638-4 gnd rswk-swf Sporentierchen (DE-588)4319742-5 gnd rswk-swf Arzneimittelentwicklung (DE-588)4143176-5 gnd rswk-swf Protozoan vaccines / Development Apicomplexa (DE-588)4143413-4 Aufsatzsammlung gnd-content Parasitäre Krankheit (DE-588)4044638-4 s Sporentierchen (DE-588)4319742-5 s Arzneimittelentwicklung (DE-588)4143176-5 s DE-604 Becker, Katja 1965- (DE-588)120316390 edt Drug discovery in infectious diseases 2 (DE-604)BV040160480 2 DNB Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=024989684&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis
spellingShingle	Apicomplexan parasites molecular approaches toward targeted drug development Drug discovery in infectious diseases Parasitäre Krankheit (DE-588)4044638-4 gnd Sporentierchen (DE-588)4319742-5 gnd Arzneimittelentwicklung (DE-588)4143176-5 gnd
subject_GND	(DE-588)4044638-4 (DE-588)4319742-5 (DE-588)4143176-5 (DE-588)4143413-4
title	Apicomplexan parasites molecular approaches toward targeted drug development
title_auth	Apicomplexan parasites molecular approaches toward targeted drug development
title_exact_search	Apicomplexan parasites molecular approaches toward targeted drug development
title_full	Apicomplexan parasites molecular approaches toward targeted drug development ed. by Katja Becker
title_fullStr	Apicomplexan parasites molecular approaches toward targeted drug development ed. by Katja Becker
title_full_unstemmed	Apicomplexan parasites molecular approaches toward targeted drug development ed. by Katja Becker
title_short	Apicomplexan parasites
title_sort	apicomplexan parasites molecular approaches toward targeted drug development
title_sub	molecular approaches toward targeted drug development
topic	Parasitäre Krankheit (DE-588)4044638-4 gnd Sporentierchen (DE-588)4319742-5 gnd Arzneimittelentwicklung (DE-588)4143176-5 gnd
topic_facet	Parasitäre Krankheit Sporentierchen Arzneimittelentwicklung Aufsatzsammlung
url	http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=024989684&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA
volume_link	(DE-604)BV040160480
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