Verfügbarkeit: TNF pathophysiology

TNF pathophysiology: molecular and cellular mechanisms

TNF is a multifunctional proinflammatory cytokine central to the development and homeostasis of the immune system and a regulator of cell activation, differentiation and death. Recent decades have seen an enormous scientific and clinical interest in the function of TNF in physiology and disease. A v...

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Weitere Verfasser:	Kollias, George 1958- (HerausgeberIn), Sfikakis, Petros P. (HerausgeberIn)
Format:	Elektronisch E-Book
Sprache:	English
Veröffentlicht:	Basel Karger 2010
Schriftenreihe:	Current directions in autoimmunity Vol. 11
Schlagworte:	Pathophysiologie Tumor-Nekrose-Faktor Aufsatzsammlung
Online-Zugang:	BFB01 BSB01 BTW01 EUV01 FAN01 FAW01 FFW01 FHI01 FHM01 FHN01 FHR01 FKE01 FNU01 FWS01 FWS02 GEM01 LCO01 SAB01 SAM01 SBG01 SBR01 SND01 TUM01 UBA01 UBG01 UBM01 UBR01 UBT01 UBW01 UER01 UPA01 Volltext
Zusammenfassung:	TNF is a multifunctional proinflammatory cytokine central to the development and homeostasis of the immune system and a regulator of cell activation, differentiation and death. Recent decades have seen an enormous scientific and clinical interest in the function of TNF in physiology and disease. A vast amount of data has been accumulated at the biochemical, molecular and cellular level, establishing TNF as a prototype for in-depth understanding of the physiological and pathogenic functions of cytokines. This volume covers several current aspects of TNF regulation and function, including transcriptional and posttranscriptional control mechanisms, cellular modes of action, signaling networks that mediate its effect, involvement in pathogenesis and clinical outcomes of TNF antagonists. It combines basic science at the molecular and cellular level with research in animal models of disease and clinical findings to provide a comprehensive review of recent developments in TNF biology. A thorough understanding of the mechanisms by which this key molecular player is produced and functions to regulate cell biology, immunity and disease postulates novel paradigms on how genes contribute to the development and physiology of biological systems. This book is mandatory reading for molecular and cell biologists, immunologists and clinicians interested in TNF function
Beschreibung:	Fascinating insights into the multiple roles of this key cytokine
Beschreibung:	1 Online-Ressource (VIII, 216 Seiten) Illustrationen, Diagramme
ISBN:	9783805593847

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genre	(DE-588)4143413-4 Aufsatzsammlung gnd-content
genre_facet	Aufsatzsammlung
id	DE-604.BV039887140
illustrated	Not Illustrated
indexdate	2024-08-01T11:46:26Z
institution	BVB
isbn	9783805593847
language	English
oai_aleph_id	oai:aleph.bib-bvb.de:BVB01-024746236
oclc_num	747899868
open_access_boolean
owner	DE-1049 DE-92 DE-898 DE-BY-UBR DE-863 DE-BY-FWS DE-862 DE-BY-FWS DE-521 DE-522 DE-526 DE-12 DE-384 DE-473 DE-BY-UBG DE-703 DE-29 DE-19 DE-BY-UBM DE-739 DE-355 DE-BY-UBR DE-20 DE-1102 DE-573 DE-859 DE-M347 DE-91 DE-BY-TUM DE-1028 DE-128 DE-54 DE-22 DE-BY-UBG DE-150 DE-155 DE-BY-UBR DE-11 DE-83 DE-M382 DE-70 DE-578 DE-1046
owner_facet	DE-1049 DE-92 DE-898 DE-BY-UBR DE-863 DE-BY-FWS DE-862 DE-BY-FWS DE-521 DE-522 DE-526 DE-12 DE-384 DE-473 DE-BY-UBG DE-703 DE-29 DE-19 DE-BY-UBM DE-739 DE-355 DE-BY-UBR DE-20 DE-1102 DE-573 DE-859 DE-M347 DE-91 DE-BY-TUM DE-1028 DE-128 DE-54 DE-22 DE-BY-UBG DE-150 DE-155 DE-BY-UBR DE-11 DE-83 DE-M382 DE-70 DE-578 DE-1046
physical	1 Online-Ressource (VIII, 216 Seiten) Illustrationen, Diagramme
psigel	ZDB-1-KEB ZDB-1-KEB10
publishDate	2010
publishDateSearch	2010
publishDateSort	2010
publisher	Karger
record_format	marc
series	Current directions in autoimmunity
series2	Current directions in autoimmunity
spellingShingle	TNF pathophysiology molecular and cellular mechanisms Current directions in autoimmunity Pathophysiologie (DE-588)4044898-8 gnd Tumor-Nekrose-Faktor (DE-588)4202932-6 gnd
subject_GND	(DE-588)4044898-8 (DE-588)4202932-6 (DE-588)4143413-4
title	TNF pathophysiology molecular and cellular mechanisms
title_auth	TNF pathophysiology molecular and cellular mechanisms
title_exact_search	TNF pathophysiology molecular and cellular mechanisms
title_full	TNF pathophysiology molecular and cellular mechanisms volume editors: G. Kollias, P. P. Sfikakis
title_fullStr	TNF pathophysiology molecular and cellular mechanisms volume editors: G. Kollias, P. P. Sfikakis
title_full_unstemmed	TNF pathophysiology molecular and cellular mechanisms volume editors: G. Kollias, P. P. Sfikakis
title_short	TNF pathophysiology
title_sort	tnf pathophysiology molecular and cellular mechanisms
title_sub	molecular and cellular mechanisms
topic	Pathophysiologie (DE-588)4044898-8 gnd Tumor-Nekrose-Faktor (DE-588)4202932-6 gnd
topic_facet	Pathophysiologie Tumor-Nekrose-Faktor Aufsatzsammlung
url	https://karger.com/books/book/2686
volume_link	(DE-604)BV039142746
work_keys_str_mv	AT kolliasgeorge tnfpathophysiologymolecularandcellularmechanisms AT sfikakispetrosp tnfpathophysiologymolecularandcellularmechanisms

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