Biochemistry for sport and exercise metabolism:
Gespeichert in:
| Hauptverfasser: | , |
|---|---|
| Format: | Buch |
| Sprache: | English |
| Veröffentlicht: |
Chichester, West Sussex
Wiley
2012
|
| Ausgabe: | 1. publ. |
| Schriftenreihe: | Wiley SportTexts Series
|
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | XIII, 249 S. Ill., zahlr. graph. Darst. |
| ISBN: | 9780470091845 9780470091852 |
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| 100 | 1 | |a MacLaren, Don |e Verfasser |4 aut | |
| 245 | 1 | 0 | |a Biochemistry for sport and exercise metabolism |c Don MacLaren ; James Morton |
| 250 | |a 1. publ. | ||
| 264 | 1 | |a Chichester, West Sussex |b Wiley |c 2012 | |
| 300 | |a XIII, 249 S. |b Ill., zahlr. graph. Darst. | ||
| 336 | |b txt |2 rdacontent | ||
| 337 | |b n |2 rdamedia | ||
| 338 | |b nc |2 rdacarrier | ||
| 490 | 0 | |a Wiley SportTexts Series | |
| 650 | 4 | |a Medizin | |
| 650 | 4 | |a Human mechanics | |
| 650 | 4 | |a Biochemistry | |
| 650 | 4 | |a Sports |x Physiological aspects | |
| 650 | 4 | |a Exercise |x Physiological aspects | |
| 650 | 4 | |a Energy metabolism | |
| 650 | 4 | |a Muscles |x Metabolism | |
| 650 | 7 | |a MEDICAL / Sports Medicine |2 bisacsh | |
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| 999 | |a oai:aleph.bib-bvb.de:BVB01-024745098 | ||
Datensatz im Suchindex
| _version_ | 1804148832597966848 |
|---|---|
| adam_text | Contents
Preface
xi
One Basic Muscle Physiology and Energetics
1
1
Energy sources for muscular activity
3
1.1
Adenosine triphosphate: the energy currency
3
1.2
Energy continuum
4
1.3
Energy supply for muscle contraction
4
1.4
Energy systems and running speed
7
1.5
Why can t a marathon be sprinted?
7
1.6
Energy sources and muscle
8
1.7
Can muscle use protein for energy?
9
1.8
Key points
10
2
Skeletal muscle structure and function
11
2.1
Skeletal muscle structure
12
2.1.1
Gross anatomical structure
12
2.1.2
The muscle fibre
13
2.2
Muscle contraction
18
2.2.1
Propagation of the action potential
18
2.2.2
Excitation-contraction coupling
18
2.2.3
The sliding filament mechanism
20
2.3
Muscle fibre types
21
2.3.1
General classification of muscle fibres
21
2.3.2
Muscle fibre distribution
23
2.3.3
Muscle fibre recruitment
24
2.4
Muscles in action
26
2.4.1
Types of muscle contraction
26
2.4.2
The twitch contraction
26
2.4.3
The length-tension relationship
27
vi
CONTENTS
2.4.4
Tetanus
contractions
27
2.4.5
Force-velocity
relationship
28
2.4.6
Muscle fatigue
29
2.5
Key points
29
3
Biochemical concepts
31
3.1
Organization of matter
32
32
32
34
34
34
35
36
36
38
39
40
40
41
42
43
45
45
46
46
47
3.6.1
Acids, bases and salts
47
3.6.2 pH
Scale
48
3.6.3
Buffers
49
3.7
Cell structure
49
3.7.1
The plasma membrane
50
3.7.2
The nucleus
51
3.7.3
Cytoplasm and
organdíes
51
3.8
Key points
53
Two Fundamentals of Sport and Exercise Biochemistry
55
4
Proteins
57
4.1
Protein function
58
4.1.1
General protein function
59
4.2
Amino
acids
62
4.2.1
Amino
acid structure
62
4.3
Protein structure
62
4.3.1
Primary structure
62
4.3.2
Secondary structure
65
4.3.3
Tertiary structure
65
3.1.1
Matter and elements
3.1.2
Atoms and atomic structure
3.1.3
Atomic number and mass number
3.1.4
Atomic mass
3.1.5
Ions, molecules, compounds and macronutrients
3.2
Chemical bonding
3.2.1
Ionic bonds
3.2.2
Covalent bonds
3.2.3
Molecular formulae and structures
3.2.4
Functional groups
3.3
Chemical reactions, ATP and energy
3.3.1
Energy
3.3.2
ATP
3.3.3
Units of energy
3.3.4
Types of chemical reactions
3.4
Water
3.4.1
General functions of water
3.4.2
Water as a solvent
3.5
Solutions and concentrations
3.6
Acid-base balance
CONTENTS
vii
65
67
67
68
70
70
72
73
73
73
74
74
76
78
79
79
80
82
82
82
85
85
87
88
^o
5.2.1 Monosaccharides 90
5.2.2 Disaccharides and polysaccharides 91
5.3
Metabolism
of carbohydrates
92
5.3.1 Glycogenolysis 93
5.3.2 Glycolysis 95
5.3.3
Lactate metabolism
98
5.3.4
The link reaction; production of acetyl-CoA
98
5.3.5
The TCA (or
Krebs)
cycle
98
5.3.6
Electron transport chain
98
5.3.7
Oxidative phosphorylation
100
5.3.8
Calculation of ATP generated in glucose oxidation
101
5.3.9
Overview of glucose oxidation
102
5.3.10
Fructose metabolism
102
5.3.11
Gluconeogenesis
102
5.3.12
Glycogenesis
103
5.4
Key points
107
Lipids
109
6.1
Relevance of lipids for sport and exercise
110
6.2
Structure of lipids
112
6.2.1
Classification of lipids
112
4.3.4
Quaternary structure
4.4
Proteins as enzymes
4.4.1
Mechanisms of enzyme action
4.4.2
Factors affecting rates of enzymatic reactions
4.4.3
Coenzymes and cofactors
4.4.4
Classification of enzymes
4.4.5
Regulation of enzyme activity
4.5
Protein
turnover
4.5.1
Overview of protein turnover
4.5.2
DNA
structure
4.5.3
Transcription
4.5.4
The genetic code
4.5.5
Translation
4.6
Amino
acid metabolism
4.6.1
Free
amino
acid pool
4.6.2
Transamination
4.6.3
Deamination
4.6.4
Branched chain
amino
acids
4.6.5
Glucose-alanine cycle
4.6.6
Glutaminę
4.6.7
The urea cycle
4.7
Key points
Carbohydrates
5.1
Relevance of carbohydrates for sport and exercise
5.2
TvDes and structure of carbohvdrates
Viii
CONTENTS
6.2.2
Compound lipids
115
6.2.3
Derived
lipids
115
6.3
Metabolism of lipids
115
6.3.1
Lipolysis
115
6.3.2 ß-oxidation 118
6.3.3
Ketone
body formation
119
6.3.4
Formation of fatty acids
119
6.3.5
Triglycéride
synthesis
122
6.4
Key points
124
Three Metabolic Regulation in Sport and Exercise
127
7
Principles of metabolic regulation
129
7.1
How are catabolic and anabolic reactions controlled?
130
7.2
Hormones
130
7.3
Peptide
hormones,
neurotransmitters
and regulation
133
7.3.1
Adrenaline activation of glycogenolysis
134
7.3.2
Adrenaline activation of lipolysis
135
7.3.3
Insulin activation of glycogen synthase
135
7.3.4
Insulin inhibition of lipolysis
137
7.3.5
Insulin stimulation of protein synthesis
137
7.4
Steroid hormones and regulation
138
7.5
Allosteric effectors
140
7.5.1
Regulation of glycogen phosphorylase
140
7.5.2
Regulation of PFK
140
7.5.3
Regulation of PDH
140
7.5.4
Regulation of CPT1
142
7.5.5
AMPK as a metabolic regulator
142
7.6
Key points
144
8
High-intensity exercise
145
8.1
Overview of energy production and metabolic regulation in high-intensity exercise
145
8.1.1
Definition of high-intensity exercise
145
8.1.2
Energy production during high-intensity exercise
146
8.1.3
Evidence of energy sources used in HIE
148
8.1.4
Metabolic regulation during high-intensity exercise
152
8.2
Effects of exercise duration
152
8.3
Effects of nutritional status
153
8.3.1
Can nutritional ergogenic aids help HIE?
154
8.4
Effects of training
155
8.5
Mechanisms of fatigue
157
8.5.1
Reduced ATP
158
8.5.2
Reduced PCr
159
8.5.3
Increased
P¡
159
8.5.4
Lactate
and H+
160
8.6
Key points
161
CONTENTS ix
9
Endurance exercise
163
9.1
Overview of energy production and metabolic regulation in endurance exercise
164
9.1.1
Definition and models of endurance exercise
164
9.1.2
Energy production in endurance exercise
164
9.1.3
Overview of metabolic regulation in endurance exercise
165
9.2
Effects of exercise intensity
166
9.2.1
CHO metabolism
166
9.2.2
Lipid
metabolism
168
9.3
Effects of exercise duration
172
9.4
Effects of nutritional status
174
9.4.1
CHO-loading and muscle glycogen availability
174
9.4.2
Fat-loading strategies
176
9.4.3
Pre-exercise and during-exercise CHO
ingestion
178
9.4.4
Pre-exercise FFA availability
181
9.5
Effects of training status
183
9.5.1
CHO metabolism
183
9.5.2
Lipid
metabolism
184
9.5.3
Protein metabolism
188
9.6
Mechanisms of fatigue
189
9.7
Key points
192
10
High-intensity intermittent exercise
195
10.1
Overview of energy production in intermittent exercise
196
10.1.1
Definition and models of intermittent exercise
196
10.1.2
Energy systems utilized in intermittent exercise
197
10.2
Metabolic regulation in intermittent exercise
197
10.3
Effects of manipulating work-rest intensity and ratio
202
10.4
Effects of nutritional status
206
10.4.1
Muscle glycogen availability
207
10.4.2
Pre-exercise CHO
ingestion
207
10.4.3
CHO
ingestion
during exercise
209
10.5
Muscle adaptations to interval training
210
10.6
Mechanisms of fatigue
215
10.6.1
Carbohydrate availability
216
10.6.2
PCr depletion
217
10.6.3
Acidosis
218
10.6.4
Extracellular potassium
220
10.6.5
Reactive oxygen species
(ROS)
221
10.6.6
Ρ,-
accumulation and impaired Ca2+ release
223
10.7
Key points
224
References and suggested readings
227
Index
241
|
| any_adam_object | 1 |
| author | MacLaren, Don Morton, James |
| author_facet | MacLaren, Don Morton, James |
| author_role | aut aut |
| author_sort | MacLaren, Don |
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| bvnumber | BV039885974 |
| classification_rvk | ZX 9400 |
| classification_tum | SPO 633 |
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| discipline | Sport Sportwissenschaft |
| edition | 1. publ. |
| format | Book |
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| id | DE-604.BV039885974 |
| illustrated | Illustrated |
| indexdate | 2024-07-10T00:13:24Z |
| institution | BVB |
| isbn | 9780470091845 9780470091852 |
| language | English |
| lccn | 2011030216 |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-024745098 |
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| physical | XIII, 249 S. Ill., zahlr. graph. Darst. |
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| publisher | Wiley |
| record_format | marc |
| series2 | Wiley SportTexts Series |
| spelling | MacLaren, Don Verfasser aut Biochemistry for sport and exercise metabolism Don MacLaren ; James Morton 1. publ. Chichester, West Sussex Wiley 2012 XIII, 249 S. Ill., zahlr. graph. Darst. txt rdacontent n rdamedia nc rdacarrier Wiley SportTexts Series Medizin Human mechanics Biochemistry Sports Physiological aspects Exercise Physiological aspects Energy metabolism Muscles Metabolism MEDICAL / Sports Medicine bisacsh Stoffwechsel (DE-588)4057699-1 gnd rswk-swf Medizin (DE-588)4038243-6 gnd rswk-swf Sport (DE-588)4056366-2 gnd rswk-swf Sport (DE-588)4056366-2 s Medizin (DE-588)4038243-6 s Stoffwechsel (DE-588)4057699-1 s DE-604 Morton, James Verfasser aut Digitalisierung UB Regensburg application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=024745098&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | MacLaren, Don Morton, James Biochemistry for sport and exercise metabolism Medizin Human mechanics Biochemistry Sports Physiological aspects Exercise Physiological aspects Energy metabolism Muscles Metabolism MEDICAL / Sports Medicine bisacsh Stoffwechsel (DE-588)4057699-1 gnd Medizin (DE-588)4038243-6 gnd Sport (DE-588)4056366-2 gnd |
| subject_GND | (DE-588)4057699-1 (DE-588)4038243-6 (DE-588)4056366-2 |
| title | Biochemistry for sport and exercise metabolism |
| title_auth | Biochemistry for sport and exercise metabolism |
| title_exact_search | Biochemistry for sport and exercise metabolism |
| title_full | Biochemistry for sport and exercise metabolism Don MacLaren ; James Morton |
| title_fullStr | Biochemistry for sport and exercise metabolism Don MacLaren ; James Morton |
| title_full_unstemmed | Biochemistry for sport and exercise metabolism Don MacLaren ; James Morton |
| title_short | Biochemistry for sport and exercise metabolism |
| title_sort | biochemistry for sport and exercise metabolism |
| topic | Medizin Human mechanics Biochemistry Sports Physiological aspects Exercise Physiological aspects Energy metabolism Muscles Metabolism MEDICAL / Sports Medicine bisacsh Stoffwechsel (DE-588)4057699-1 gnd Medizin (DE-588)4038243-6 gnd Sport (DE-588)4056366-2 gnd |
| topic_facet | Medizin Human mechanics Biochemistry Sports Physiological aspects Exercise Physiological aspects Energy metabolism Muscles Metabolism MEDICAL / Sports Medicine Stoffwechsel Sport |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=024745098&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
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